-
1
-
-
77649202241
-
Reoperation for bleeding in patients undergoing coronary artery bypass surgery: Incidence, risk factors, time trends, and outcomes
-
Mehta RH, Sheng S, O'Brien SM, et al. Reoperation for bleeding in patients undergoing coronary artery bypass surgery: incidence, risk factors, time trends, and outcomes. Circ Cardiovasc Qual Outcomes 2009; 2: 583-90
-
(2009)
Circ Cardiovasc Qual Outcomes
, vol.2
, pp. 583-590
-
-
Mehta, R.H.1
Sheng, S.2
O'Brien, S.M.3
-
2
-
-
36549084598
-
Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery
-
Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 2007; 116: 2544-52
-
(2007)
Circulation
, vol.116
, pp. 2544-2552
-
-
Murphy, G.J.1
Reeves, B.C.2
Rogers, C.A.3
Rizvi, S.I.4
Culliford, L.5
Angelini, G.D.6
-
4
-
-
85016248438
-
Normal haemostasis
-
Hoffbrand AV, Catovsky D, Tuddenham EGD, eds,Oxford: Wiley-Blackwell
-
Gomez K, Tuddenham EGD, McVey JH. Normal haemostasis. In: Hoffbrand AV, Catovsky D, Tuddenham EGD, eds. Postgraduate Haematology. Oxford: Wiley-Blackwell, 2011
-
(2011)
Postgraduate Haematology
-
-
Gomez, K.1
Tuddenham, E.G.D.2
McVey, J.H.3
-
5
-
-
0010973257
-
Therapy with antifibrinolytic agents
-
ColmanRW, Hirsch J, Marder V, Clowes A, George J, eds, Philadelphia: Lippincott Williams & Wilkins
-
Hedner U, Hirsch J, Marder V. Therapy with Antifibrinolytic Agents. In: ColmanRW, Hirsch J, Marder V, Clowes A, George J, eds. Hemostasis and Thrombosis : Basic Principles and Clinical Practice. Philadelphia: Lippincott Williams & Wilkins, 2001
-
(2001)
Hemostasis and Thrombosis : Basic Principles and Clinical Practice
-
-
Hedner, U.1
Hirsch, J.2
Marder, V.3
-
6
-
-
0030060802
-
Reducing thrombinformation during cardiopulmonary bypass: Is there a benefit of the additional anticoagulant action of aprotinin?
-
DietrichW. Reducing thrombinformation during cardiopulmonary bypass: is there a benefit of the additional anticoagulant action of aprotinin? J Cardiovasc Pharmacol 1996; 27 (Suppl. 1): S50-7
-
(1996)
J Cardiovasc Pharmacol
, vol.27
, Issue.SUPPL.1
-
-
Dietrich, W.1
-
7
-
-
0027300477
-
Aprotinin in perspective
-
Westaby S. Aprotinin in perspective. Ann Thorac Surg 1993; 55: 1033-41
-
(1993)
Ann Thorac Surg
, vol.55
, pp. 1033-1041
-
-
Westaby, S.1
-
8
-
-
0034778665
-
The effects of aprotininandsteroidson generation of cytokines during coronary artery surgery
-
Turkoz A, Cigli A, But K, et al. The effects of aprotininandsteroidson generation of cytokines during coronary artery surgery. J Cardiothorac Anesth 2001; 15: 603-10
-
(2001)
J Cardiothorac Anesth
, vol.15
, pp. 603-610
-
-
Turkoz, A.1
Cigli, A.2
But, K.3
-
9
-
-
0345356441
-
Antifibrinolytic therapy during cardiopulmonary bypass reduces proinflammatory cytokine levels: A randomized, double-blind, placebo-controlled study of epsilon-aminocaproic acid and aprotinin
-
Greilich PE, Brouse CF, Whitten CW, Chi L, Dimaio JM, Jessen ME. Antifibrinolytic therapy during cardiopulmonary bypass reduces proinflammatory cytokine levels: a randomized, double-blind, placebo-controlled study of epsilon-aminocaproic acid and aprotinin. J Thorac Cardiovasc Surg 2003; 126: 1498-503
-
(2003)
J Thorac Cardiovasc Surg
, vol.126
, pp. 1498-1503
-
-
Greilich, P.E.1
Brouse, C.F.2
Whitten, C.W.3
Chi, L.4
Dimaio, J.M.5
Jessen, M.E.6
-
10
-
-
42449095077
-
Differential effects of epsilon-aminocaproic acidand aprotinin onmatrix metalloproteinase release in patients following cardiopulmonary bypass
-
Dorman BH, Stroud RE, Wyckoff MM, et al. Differential effects of epsilon-aminocaproic acidand aprotinin onmatrix metalloproteinase release in patients following cardiopulmonary bypass. J Cardiovasc Pharmacol 2008; 51: 418-23
-
(2008)
J Cardiovasc Pharmacol
, vol.51
, pp. 418-423
-
-
Dorman, B.H.1
Stroud, R.E.2
Wyckoff, M.M.3
-
11
-
-
0028972012
-
Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans
-
Hill GE, Alonso A, Spurzem JR,Stammers AH, Robbins RA. Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans. J Thorac Cardiovasc Surg 1995; 110: 1658-62
-
(1995)
J Thorac Cardiovasc Surg
, vol.110
, pp. 1658-1662
-
-
Hill, G.E.1
Alonso, A.2
Spurzem, J.R.3
Stammers, A.H.4
Robbins, R.A.5
-
12
-
-
0035908926
-
Aprotinin but not epsilon-aminocaproic acid decreases interleukin-10 after cardiac surgery with extracorporeal circulation: Randomized, double-blind, placebo-controlled study in patients receiving aprotinin and epsilon-aminocaproic acid
-
Greilich PE,Okada K, LathamP, KumarRR, Jessen ME. Aprotinin but not epsilon-aminocaproic acid decreases interleukin-10 after cardiac surgery with extracorporeal circulation: randomized, double-blind, placebo-controlled study in patients receiving aprotinin and epsilon-aminocaproic acid. Circulation 2001; 104: I265-9
-
(2001)
Circulation
, vol.104
-
-
Greilich, P.E.1
Okada, K.2
Latham, P.3
Kumar, R.R.4
Jessen, M.E.5
-
13
-
-
77954674960
-
Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass
-
Homi HM, Sheng H, Arepally GM, Mackensen GB, Grocott HP. Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass. Anesth Analg 2010; 111: 38-45
-
(2010)
Anesth Analg
, vol.111
, pp. 38-45
-
-
Homi, H.M.1
Sheng, H.2
Arepally, G.M.3
Mackensen, G.B.4
Grocott, H.P.5
-
15
-
-
0023204701
-
Effect of aprotinin on need for blood transfusion after repeat open- heart surgery
-
Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open- heart surgery. Lancet 1987; 2: 1289-91
-
(1987)
Lancet
, vol.2
, pp. 1289-1291
-
-
Royston, D.1
Bidstrup, B.P.2
Taylor, K.M.3
Sapsford, R.N.4
-
16
-
-
34548681125
-
Aprotinin and anaphylaxis: Analysis of 12,403 exposures to aprotinin in zardiac surgery
-
DietrichW, Ebell A, Busley R, Boulesteix AL. Aprotinin and anaphylaxis: analysis of 12,403 exposures to aprotinin in zardiac surgery. Ann Thorac Surg 2007; 84: 1144-50
-
(2007)
Ann Thorac Surg
, vol.84
, pp. 1144-1150
-
-
Dietrich, W.1
Ebell, A.2
Busley, R.3
Boulesteix, A.L.4
-
17
-
-
4444380033
-
Effect of aprotininonclinical outcomes in coronary artery bypass graft surgery: A systematic review and meta-analysis of randomized clinical trials
-
SedrakyanA, Treasure T, Elefteriades JA. Effect of aprotininonclinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials. J Thorac Cardiovasc Surg 2004; 128: 442-8
-
(2004)
J Thorac Cardiovasc Surg
, vol.128
, pp. 442-448
-
-
Sedrakyan, A.1
Treasure, T.2
Elefteriades, J.A.3
-
18
-
-
31344467254
-
The risk associated with aprotinin in cardiac surgery
-
ManganoDT, Tudor IC, Dietzel C. The risk associated with aprotinin in cardiac surgery. N Engl J Med 2006; 354: 353-65
-
(2006)
N Engl J Med
, vol.354
, pp. 353-365
-
-
Mangano, D.T.1
Tudor, I.C.2
Dietzel, C.3
-
19
-
-
44349089188
-
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery
-
Fergusson DA, Hebert PC, Mazer CD, et al. A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med 2008; 358: 2319-31
-
(2008)
N Engl J Med
, vol.358
, pp. 2319-2331
-
-
Fergusson, D.A.1
Hebert, P.C.2
Mazer, C.D.3
-
20
-
-
79952270874
-
Anti-fibrinolytic use for minimizing perioperative allogeneic blood transfusion
-
HenryDA, Carless PA,Moxey AJ, et al. Anti-fibrinolytic use for minimizing perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2011; 1: CD001886
-
(2011)
Cochrane Database Syst Rev
, vol.1
-
-
Henry, D.A.1
Carless, P.A.2
Moxey, A.J.3
-
21
-
-
84856965398
-
-
Health Canada, Available from, (accessed 7 April 2012)
-
Health Canada. Health Canada decision on Trasylol (aprotinin). Available from http://www.hc-sc.gc.ca/ahc-asc/media/advisoriesavis/-2011/2011-124-eng.php (accessed 7 April 2012)
-
Health Canada decision on Trasylol (aprotinin)
-
-
-
24
-
-
79952270874
-
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
-
Henry DA, Carless PA, Moxey AJ, et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2007; 4: CD001886
-
(2007)
Cochrane Database Syst Rev
, vol.4
-
-
Henry, D.A.1
Carless, P.A.2
Moxey, A.J.3
-
25
-
-
84888217287
-
-
Okamoto S. British Patent Specification No. 770,693. London: Her Majesty's Stationery Office, 1957
-
Okamoto S. British Patent Specification No. 770,693. London: Her Majesty's Stationery Office, 1957
-
-
-
-
26
-
-
0021954364
-
Clinical application of inhibitors of fibrinolysis
-
Verstraete M. Clinical application of inhibitors of fibrinolysis. Drugs 1985; 29: 236-61
-
(1985)
Drugs
, vol.29
, pp. 236-261
-
-
Verstraete, M.1
-
27
-
-
0004195999
-
-
4th edn. Philadelphia:Lippincott Williams
-
Coleman R, Hirsch J, Marder V, Clowes A, George J. Hemostasis and Thrombosis, Principles and Practice, 4th edn. Philadelphia: Lippincott Williams, 2000
-
(2000)
Hemostasis and Thrombosis, Principles and Practice
-
-
Coleman, R.1
Hirsch, J.2
Marder, V.3
Clowes, A.4
George, J.5
-
28
-
-
0026005804
-
Hemostatic effects of tranexamic acid and desmopressin during cardiac surgery
-
Horrow JC, Van Riper DF, Strong MD, Brodsky I, Parmet JL. Hemostatic effects of tranexamic acid and desmopressin during cardiac surgery. Circulation 1991; 84: 2063-70
-
(1991)
Circulation
, vol.84
, pp. 2063-2070
-
-
Horrow, J.C.1
Van Riper, D.F.2
Strong, M.D.3
Brodsky, I.4
Parmet, J.L.5
-
29
-
-
0030004024
-
Tranexamic acid reduces transfusions and mediastinal drainage in repeat cardiac surgery
-
Shore-Lesserson L, Reich DL, Vela-Cantos F, Ammar T, Ergin MA. Tranexamic acid reduces transfusions and mediastinal drainage in repeat cardiac surgery. Anesth Analg 1996; 83: 18-26
-
(1996)
Anesth Analg
, vol.83
, pp. 18-26
-
-
Shore-Lesserson, L.1
Reich, D.L.2
Vela-Cantos, F.3
Ammar, T.4
Ergin, M.A.5
-
30
-
-
0029102222
-
Prevention of bleedingafter cardiopulmonarybypass with high-dose tranexamic acid. Doubleblind, randomizedclinical trial
-
Karski JM, Teasdale SJ,NormanP, et al. Prevention of bleedingafter cardiopulmonarybypass with high-dose tranexamic acid. Doubleblind, randomizedclinical trial. J ThoracCardiovasc Surg 1995;110: 835-42
-
(1995)
J ThoracCardiovasc Surg
, vol.110
, pp. 835-842
-
-
Karski, J.M.1
Teasdale, S.J.2
Norman, P.3
-
31
-
-
0028797713
-
The dose-response relationship of tranexamic acid
-
Horrow JC, Van Riper DF, Strong MD, Grunewald KE, Parmet JL. The dose-response relationship of tranexamic acid. Anesthesiology 1995; 82: 383-92
-
(1995)
Anesthesiology
, vol.82
, pp. 383-392
-
-
Horrow, J.C.1
Van Riper, D.F.2
Strong, M.D.3
Grunewald, K.E.4
Parmet, J.L.5
-
32
-
-
0032587586
-
Pharmacokinetics of epsilon-aminocaproic acid in patients undergoing aortocoronary bypass surgery
-
Butterworth J, James RL, Lin Y, Prielipp RC, Hudspeth AS. Pharmacokinetics of epsilon-aminocaproic acid in patients undergoing aortocoronary bypass surgery. Anesthesiology 1999; 90: 1624-35
-
(1999)
Anesthesiology
, vol.90
, pp. 1624-1635
-
-
Butterworth, J.1
James, R.L.2
Lin, Y.3
Prielipp, R.C.4
Hudspeth, A.S.5
-
33
-
-
58149293358
-
The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients
-
Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients. Anesth Analg 2008; 107: 1783-90
-
(2008)
Anesth Analg
, vol.107
, pp. 1783-1790
-
-
Martin, K.1
Wiesner, G.2
Breuer, T.3
Lange, R.4
Tassani, P.5
-
34
-
-
76249100902
-
High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients
-
Murkin JM, Falter F, Granton J, Young B, Burt C, Chu M. High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients. Anesth Analg 2010; 110: 350-3
-
(2010)
Anesth Analg
, vol.110
, pp. 350-353
-
-
Murkin, J.M.1
Falter, F.2
Granton, J.3
Young, B.4
Burt, C.5
Chu, M.6
-
35
-
-
66349098659
-
Polymyoclonus seizure resulting fromaccidental injection of tranexamic acid in spinal anesthesia
-
Mohseni K, Jafari A, Nobahar MR, Arami A. Polymyoclonus seizure resulting fromaccidental injection of tranexamic acid in spinal anesthesia. Anesth Analg 2009; 108: 1984-6
-
(2009)
Anesth Analg
, vol.108
, pp. 1984-1986
-
-
Mohseni, K.1
Jafari, A.2
Nobahar, M.R.3
Arami, A.4
-
36
-
-
33847678904
-
Death after an inadvertent intrathecal injection of tranexamic acid
-
Garcha PS, Mohan CV, Sharma RM. Death after an inadvertent intrathecal injection of tranexamic acid. Anesth Analg 2007; 104: 241-2
-
(2007)
Anesth Analg
, vol.104
, pp. 241-242
-
-
Garcha, P.S.1
Mohan, C.V.2
Sharma, R.M.3
-
37
-
-
0037219816
-
LauHP, Lin PL, SunWZ,MokMS.Convulsionsandrefractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid
-
YehHM,LauHP, Lin PL, SunWZ,MokMS.Convulsionsandrefractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid. Anesthesiology 2003; 98: 270-2
-
(2003)
Anesthesiology
, vol.98
, pp. 270-272
-
-
Yeh, H.M.1
-
38
-
-
79251578607
-
Seizures after open heart surgery: Comparison of epsilon-aminocaproic acid and tranexamic acid
-
Martin K, Knorr J, Breuer T, et al. Seizures after open heart surgery: comparison of epsilon-aminocaproic acid and tranexamic acid. J Cardiothorac Anesth 2011; 25: 20-5
-
(2011)
J Cardiothorac Anesth
, vol.25
, pp. 20-25
-
-
Martin, K.1
Knorr, J.2
Breuer, T.3
-
39
-
-
57549085150
-
The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery
-
Breuer T, Martin K, Wilhelm M, et al. The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery. Eur J Cardiothorac Surg 2009; 35: 167-71
-
(2009)
Eur J Cardiothorac Surg
, vol.35
, pp. 167-171
-
-
Breuer, T.1
Martin, K.2
Wilhelm, M.3
-
40
-
-
79954600429
-
High-dose tranexamic acid is related to increased risk of generalized seizures after aortic valve replacement
-
Keyl C, Uhl R, Beyersdorf F, et al. High-dose tranexamic acid is related to increased risk of generalized seizures after aortic valve replacement. Eur J Cardiothorac Surg 2011; 39: e114-21
-
(2011)
Eur J Cardiothorac Surg
, vol.39
-
-
Keyl, C.1
Uhl, R.2
Beyersdorf, F.3
-
41
-
-
84055192250
-
High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass
-
Kalavrouziotis D, Voisine P, Mohammadi S, Dionne S, Dagenais F. High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass. Ann Thorac Surg 2012; 93: 148-54
-
(2012)
Ann Thorac Surg
, vol.93
, pp. 148-154
-
-
Kalavrouziotis, D.1
Voisine, P.2
Mohammadi, S.3
Dionne, S.4
Dagenais, F.5
-
42
-
-
84856953707
-
Seizures following cardiac surgery: The impact of tranexamic acid and other risk factors
-
Manji RA, Grocott HP, Leake J, et al. Seizures following cardiac surgery: the impact of tranexamic acid and other risk factors. Can J Anaesth 2012; 59: 6-13
-
(2012)
Can J Anaesth
, vol.59
, pp. 6-13
-
-
Manji, R.A.1
Grocott, H.P.2
Leake, J.3
-
43
-
-
78049239997
-
Safetyand efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: Review of 200 patients
-
BermanM, Cardone D, Sharples L, et al. Safetyand efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients. Ann Thorac Surg 2010; 90: 1432-6
-
(2010)
Ann Thorac Surg
, vol.90
, pp. 1432-1436
-
-
Berman, M.1
Cardone, D.2
Sharples, L.3
-
44
-
-
84870526551
-
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors
-
Lecker I,Wang DS, Romaschin AD, Peterson M, Mazer CD, Orser BA. Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. J Clin Invest 2012; 122: 4654-66
-
(2012)
J Clin Invest
, vol.122
, pp. 4654-4666
-
-
Lecker, I.1
Wang, D.S.2
Romaschin, A.D.3
Peterson, M.4
Mazer, C.D.5
Orser, B.A.6
-
45
-
-
0017040994
-
Fibrinolysis and disseminated intravascular coagulation in open heart surgery
-
Umlas J. Fibrinolysis and disseminated intravascular coagulation in open heart surgery. Transfusion 1976; 16: 460-3
-
(1976)
Transfusion
, vol.16
, pp. 460-463
-
-
Umlas, J.1
-
46
-
-
0024598672
-
Alterations in coagulation and fibrinolysis associated with cardiopulmonary bypass during open heart surgery
-
TanakaK, TakaoM,YadaI,YuasaH,KusagawaM,DeguchiK. Alterations in coagulation and fibrinolysis associated with cardiopulmonary bypass during open heart surgery. J Cardiothorac Anesth 1989; 3: 181-8
-
(1989)
J Cardiothorac Anesth
, vol.3
, pp. 181-188
-
-
Tanaka, K.1
Takao, M.2
Yada, I.3
Yuasa, H.4
Kusagawa, M.5
Deguchi, K.6
-
47
-
-
34249913425
-
Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery
-
Brown JR, Birkmeyer NJ, O'Connor GT. Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery. Circulation 2007; 115: 2801-13
-
(2007)
Circulation
, vol.115
, pp. 2801-2813
-
-
Brown, J.R.1
Birkmeyer, N.J.2
O'Connor, G.T.3
-
48
-
-
77952582367
-
Lessons from aprotinin: Is the routine use and inconsistent dosing of tranexamic acid prudent? Meta-analysis of randomised and large matched observational studies
-
Ngaage DL, Bland JM. Lessons from aprotinin: is the routine use and inconsistent dosing of tranexamic acid prudent? Meta-analysis of randomised and large matched observational studies. Eur J Cardiothorac Surg 2010; 37: 1375-83
-
(2010)
Eur J Cardiothorac Surg
, vol.37
, pp. 1375-1383
-
-
Ngaage, D.L.1
Bland, J.M.2
-
49
-
-
74049141396
-
The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery
-
Karkouti K, Wijeysundera DN, Yau TM, McCluskey SA, Tait G, Beattie WS. The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. Anesth Analg 2010; 110: 21-9
-
(2010)
Anesth Analg
, vol.110
, pp. 21-29
-
-
Karkouti, K.1
Wijeysundera, D.N.2
Yau, T.M.3
McCluskey, S.A.4
Tait, G.5
Beattie, W.S.6
-
50
-
-
77955117750
-
Mortalityassociated withadministrationof high-dose tranexamic acid and aprotinin in primary open-heart procedures: A retrospective analysis
-
Sander M, Spies CD, Martiny V, Rosenthal C, Wernecke KD, von HeymannC. Mortalityassociated withadministrationof high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis. Crit Care 2010; 14: R148
-
(2010)
Crit Care
, vol.14
-
-
Sander, M.1
Spies, C.D.2
Martiny, V.3
Rosenthal, C.4
Wernecke, K.D.5
Von Heymann, C.6
-
51
-
-
67650081255
-
Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: A non-sponsored, double-blind, randomised, placebo-controlled trial
-
Later AF, Maas JJ, Engbers FH, et al. Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: a non-sponsored, double-blind, randomised, placebo-controlled trial. Eur J Cardiothorac Surg 2009; 36: 322-9
-
(2009)
Eur J Cardiothorac Surg
, vol.36
, pp. 322-329
-
-
Later, A.F.1
Maas, J.J.2
Engbers, F.H.3
-
52
-
-
67650687046
-
The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: A randomized, double-blind, placebocontrolled, noninferiority trial
-
Greilich PE, Jessen ME, Satyanarayana N, et al. The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebocontrolled, noninferiority trial. Anesth Analg 2009; 109: 15-24
-
(2009)
Anesth Analg
, vol.109
, pp. 15-24
-
-
Greilich, P.E.1
Jessen, M.E.2
Satyanarayana, N.3
-
53
-
-
84862784609
-
Comparative analysis of antifibrinolytic medications in pediatric heart surgery
-
Pasquali SK, Li JS, He X, et al. Comparative analysis of antifibrinolytic medications in pediatric heart surgery. J ThoracCardiovasc Surg 2012; 143: 550-7
-
(2012)
J ThoracCardiovasc Surg
, vol.143
, pp. 550-557
-
-
Pasquali, S.K.1
Li, J.S.2
He, X.3
-
54
-
-
84255205031
-
Effect of tranexamic acid on blood loss in pediatric cardiac surgery: A randomized trial
-
Shimizu K, Toda Y, Iwasaki T, et al. Effect of tranexamic acid on blood loss in pediatric cardiac surgery: a randomized trial. J Anesth 2011; 25: 823-30
-
(2011)
J Anesth
, vol.25
, pp. 823-830
-
-
Shimizu, K.1
Toda, Y.2
Iwasaki, T.3
-
55
-
-
79955619126
-
Tranexamic acid versus varepsilon-aminocaproic acid: Efficacy and safety in paediatric cardiac surgery
-
Martin K, Breuer T, Gertler R, et al. Tranexamic acid versus varepsilon-aminocaproic acid: efficacy and safety in paediatric cardiac surgery. Eur J Cardiothorac Surg 2011; 39: 892-7
-
(2011)
Eur J Cardiothorac Surg
, vol.39
, pp. 892-897
-
-
Martin, K.1
Breuer, T.2
Gertler, R.3
-
56
-
-
81855206568
-
Switch from aprotinin to epsilon-aminocaproic acid: Impact on blood loss, transfusion, and clinical outcome in neonates undergoing cardiac surgery
-
Martin K, Gertler R, Liermann H, et al. Switch from aprotinin to epsilon-aminocaproic acid: impact on blood loss, transfusion, and clinical outcome in neonates undergoing cardiac surgery. Br J Anaesth 2011; 107: 934-9
-
(2011)
Br J Anaesth
, vol.107
, pp. 934-939
-
-
Martin, K.1
Gertler, R.2
Liermann, H.3
-
57
-
-
84875638067
-
Replacement of aprotinin by {varepsilon}-aminocaproic acid in infants undergoing cardiac surgery: Consequences for blood loss and outcome
-
Martin K, Gertler R, Macguill M, et al. Replacement of aprotinin by {varepsilon}-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome. Br J Anaesth 2013; 110: 615-21
-
(2013)
Br J Anaesth
, vol.110
, pp. 615-621
-
-
Martin, K.1
Gertler, R.2
Macguill, M.3
-
58
-
-
11444268290
-
Does off-pump coronaryarterybypass reduce mortality, morbidity, andresource utilization when compared with conventional coronary artery bypass? A meta-analysis of randomized trials
-
Cheng DC, Bainbridge D, Martin JE, Novick RJ. Does off-pump coronaryarterybypass reduce mortality, morbidity,andresource utilization when compared with conventional coronary artery bypass? A meta-analysis of randomized trials. Anesthesiology 2005; 102: 188-203
-
(2005)
Anesthesiology
, vol.102
, pp. 188-203
-
-
Cheng, D.C.1
Bainbridge, D.2
Martin, J.E.3
Novick, R.J.4
-
59
-
-
37349098162
-
Off-pump coronary artery bypass leads to a regional hypercoagulable state not detectable using systemic markers
-
Kon ZN, Kwon MH, Collins MJ, et al. Off-pump coronary artery bypass leads to a regional hypercoagulable state not detectable using systemic markers. Innovations (Phila) 2006; 1: 232-8
-
(2006)
Innovations (Phila)
, vol.1
, pp. 232-238
-
-
Kon, Z.N.1
Kwon, M.H.2
Collins, M.J.3
-
60
-
-
79959215875
-
Hypercoagulable state after off-pump coronary artery bypass grafting: Evidence, mechanisms and implications
-
Raja SG, Akhtar S. Hypercoagulable state after off-pump coronary artery bypass grafting: evidence, mechanisms and implications. Expert Rev Cardiovasc Ther 2011; 9: 599-608
-
(2011)
Expert Rev Cardiovasc Ther
, vol.9
, pp. 599-608
-
-
Raja, S.G.1
Akhtar, S.2
-
61
-
-
49549087337
-
Is aprotinin safe to use in a cohort at increased risk for thrombotic events: Results from a randomized, prospective trial in off-pump coronary artery bypass
-
discussion 815-22
-
Grant MC, Kon Z, Joshi A, et al. Is aprotinin safe to use in a cohort at increased risk for thrombotic events: results from a randomized, prospective trial in off-pump coronary artery bypass. Ann Thorac Surg 2008; 86: 815-22; discussion 815-22
-
(2008)
Ann Thorac Surg
, vol.86
, pp. 815-822
-
-
Grant, M.C.1
Kon, Z.2
Joshi, A.3
-
62
-
-
70350719521
-
A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery
-
Desai PH, Kurian D, Thirumavalavan N, et al. A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery. Anesth Analg 2009; 109: 1387-94
-
(2009)
Anesth Analg
, vol.109
, pp. 1387-1394
-
-
Desai, P.H.1
Kurian, D.2
Thirumavalavan, N.3
-
63
-
-
79251598195
-
Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: A systematic review and meta-analysis
-
Adler Ma SC, Brindle W, Burton G, et al. Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: a systematic review and meta-analysis. J Cardiothorac Vasc Anesth 2011; 25: 26-35
-
(2011)
J Cardiothorac Vasc Anesth
, vol.25
, pp. 26-35
-
-
Adler Ma, S.C.1
Brindle, W.2
Burton, G.3
-
64
-
-
84864414281
-
Tranexamic acid reduces blood loss after off-pump coronary surgery: A prospective, randomized, double-blind, placebo-controlled study
-
Wang G, Xie G, Jiang T, et al. Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study. Anesth Analg 2012; 115: 239-43
-
(2012)
Anesth Analg
, vol.115
, pp. 239-243
-
-
Wang, G.1
Xie, G.2
Jiang, T.3
-
65
-
-
79951486084
-
Tranexamic acid partially improves platelet function in patients treated with dual antiplatelet therapy
-
Weber CF, Gorlinger K, Byhahn C, et al. Tranexamic acid partially improves platelet function in patients treated with dual antiplatelet therapy. Eur J Anaesthesiol 2011; 28: 57-62
-
(2011)
Eur J Anaesthesiol
, vol.28
, pp. 57-62
-
-
Weber, C.F.1
Gorlinger, K.2
Byhahn, C.3
-
66
-
-
81855194434
-
First-line therapy with coagulation factor concentrates combined with point- of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: A retrospective, singlecenter cohort study
-
Gorlinger K, Dirkmann D, Hanke AA, et al. First-line therapy with coagulation factor concentrates combined with point- of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, singlecenter cohort study. Anesthesiology 2011; 115: 1179-91
-
(2011)
Anesthesiology
, vol.115
, pp. 1179-1191
-
-
Gorlinger, K.1
Dirkmann, D.2
Hanke, A.A.3
-
67
-
-
33847264379
-
Earlycoagulopathyin multiple injury: An analysis from the German Trauma registry on 8724 patients
-
MaegeleM, Lefering R,Yucel N, et al.Earlycoagulopathyin multiple injury: an analysis from the German Trauma Registry on 8724 patients. Injury 2007; 38: 298-304
-
(2007)
Injury
, vol.38
, pp. 298-304
-
-
Maegele, M.1
Lefering, R.2
Yucel, N.3
-
68
-
-
0038448077
-
Early coagulopathy predicts mortality in trauma
-
MacLeod JB, Lynn M, McKenney MG, Cohn SM, Murtha M. Early coagulopathy predicts mortality in trauma. J Trauma 2003; 55: 39-44
-
(2003)
J Trauma
, vol.55
, pp. 39-44
-
-
MacLeod, J.B.1
Lynn, M.2
McKenney, M.G.3
Cohn, S.M.4
Murtha, M.5
-
69
-
-
67650645257
-
The coagulopathy of trauma: A review of mechanisms
-
Hess JR, Brohi K, Dutton RP, et al. The coagulopathy of trauma: a review of mechanisms. J Trauma 2008; 65: 748-54
-
(2008)
J Trauma
, vol.65
, pp. 748-754
-
-
Hess, J.R.1
Brohi, K.2
Dutton, R.P.3
-
70
-
-
44649109632
-
Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients
-
Levrat A, Gros A, Rugeri L, et al. Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients. Br J Anaesth 2008; 100: 792-7
-
(2008)
Br J Anaesth
, vol.100
, pp. 792-797
-
-
Levrat, A.1
Gros, A.2
Rugeri, L.3
-
71
-
-
70350459505
-
Hyperfibrinolysis after major trauma: Differential diagnosis of lysis patterns and prognostic value of thrombelastometry
-
Schochl H, Frietsch T, Pavelka M, Jambor C. Hyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombelastometry. J Trauma 2009; 67: 125-31
-
(2009)
J Trauma
, vol.67
, pp. 125-131
-
-
Schochl, H.1
Frietsch, T.2
Pavelka, M.3
Jambor, C.4
-
72
-
-
80051737043
-
Prevalence and impact of abnormal rotem(R) assays in severe blunt trauma: Results of the 'diagnosis and treatment of trauma-induced coagulopathy (DIA-TRE-TIC) study'
-
Tauber H, Innerhofer P, Breitkopf R, et al. Prevalence and impact of abnormal ROTEM(R) assays in severe blunt trauma: results of the 'Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC) study'. Br J Anaesth 2011; 107: 378-87
-
(2011)
Br J Anaesth
, vol.107
, pp. 378-387
-
-
Tauber, H.1
Innerhofer, P.2
Breitkopf, R.3
-
73
-
-
80055079344
-
Hyperfibrinolysis diagnosed by rotational thromboelastometry (ROTEM) is associated with higher mortality in patients with severe trauma
-
Theusinger OM, Wanner GA, Emmert MY, et al. Hyperfibrinolysis diagnosed by rotational thromboelastometry (ROTEM) is associated with higher mortality in patients with severe trauma. Anesth Analg 2011; 113: 1003-12
-
(2011)
Anesth Analg
, vol.113
, pp. 1003-1012
-
-
Theusinger, O.M.1
Wanner, G.A.2
Emmert, M.Y.3
-
74
-
-
72249118386
-
Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy
-
Brenni M,Worn M, Bruesch M, Spahn DR, Ganter MT. Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. Acta Anaesthesiol Scand 2010; 54: 111-7
-
(2010)
Acta Anaesthesiol Scand
, vol.54
, pp. 111-117
-
-
Brenni, M.1
Worn, M.2
Bruesch, M.3
Spahn, D.R.4
Ganter, M.T.5
-
75
-
-
77954717667
-
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): A randomised, placebo-controlled trial
-
Shakur H, Roberts I, Bautista R, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23-32
-
(2010)
Lancet
, vol.376
, pp. 23-32
-
-
Shakur, H.1
Roberts, I.2
Bautista, R.3
-
76
-
-
79953163189
-
The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trial
-
Roberts I, Shakur H, Afolabi A, et al. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 2011; 377: 1096-101
-
(2011)
Lancet
, vol.377
, pp. 1096-1101
-
-
Roberts, I.1
Shakur, H.2
Afolabi, A.3
-
78
-
-
79960688357
-
Effect of tranexamic acid in traumatic brain injury:A nested randomised, placebo controlled trial (CRASH-2 intracranial bleeding study)
-
Effect of tranexamic acid in traumatic brain injury:a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study). Br Med J 2011; 343: d3795
-
(2011)
Br Med J
, vol.343
-
-
-
79
-
-
77950525508
-
Management of bleeding following major trauma: An updated European guideline
-
Rossaint R, Bouillon B, Cerny V, et al. Management of bleeding following major trauma: an updated European guideline. Crit Care 2010; 14: R52
-
(2010)
Crit Care
, vol.14
-
-
Rossaint, R.1
Bouillon, B.2
Cerny, V.3
-
81
-
-
56149092917
-
Tranexamic acid reduces perioperative blood loss in adult patients having spinal fusion surgery
-
Wong J, El Beheiry H, Rampersaud YR, et al. Tranexamic acid reduces perioperative blood loss in adult patients having spinal fusion surgery. Anesth Analg 2008; 107: 1479-86
-
(2008)
Anesth Analg
, vol.107
, pp. 1479-1486
-
-
Wong, J.1
El Beheiry, H.2
Rampersaud, Y.R.3
-
82
-
-
84860342335
-
Are antifibrinolytics helpful in decreasing blood loss and transfusions during spinal fusion surgery in children with cerebral palsy scoliosis?
-
Dhawale AA, Shah SA, Sponseller PD, et al. Are antifibrinolytics helpful in decreasing blood loss and transfusions during spinal fusion surgery in children with cerebral palsy scoliosis? Spine 2012; 37: E549-55
-
(2012)
Spine
, vol.37
-
-
Dhawale, A.A.1
Shah, S.A.2
Sponseller, P.D.3
-
83
-
-
77951468688
-
A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery
-
Verma K, Errico TJ, Vaz KM, Lonner BS. A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery. BMC Surg 2010; 10: 13
-
(2010)
BMC Surg
, vol.10
, pp. 13
-
-
Verma, K.1
Errico, T.J.2
Vaz, K.M.3
Lonner, B.S.4
-
84
-
-
33750468330
-
Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?
-
Zufferey P, Merquiol F, Laporte S, et al. Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery? Anesthesiology 2006; 105: 1034-46
-
(2006)
Anesthesiology
, vol.105
, pp. 1034-1046
-
-
Zufferey, P.1
Merquiol, F.2
Laporte, S.3
-
85
-
-
60449090703
-
Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: A systematic review of randomized trials
-
Kagoma YK, Crowther MA, Douketis J, Bhandari M, Eikelboom J, Lim W. Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: a systematic review of randomized trials. Thromb Res 2009; 123: 687-96
-
(2009)
Thromb Res
, vol.123
, pp. 687-696
-
-
Kagoma, Y.K.1
Crowther, M.A.2
Douketis, J.3
Bhandari, M.4
Eikelboom, J.5
Lim, W.6
-
86
-
-
0035013868
-
Hyperfibrinolytic activity in hospitalized cirrhotic patients in a referral liver unit
-
Hu KQ, Yu AS, Tiyyagura L, Redeker AG, Reynolds TB. Hyperfibrinolytic activity in hospitalized cirrhotic patients in a referral liver unit. Am J Gastroenterol 2001; 96: 1581-6
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 1581-1586
-
-
Hu, K.Q.1
Yu, A.S.2
Tiyyagura, L.3
Redeker, A.G.4
Reynolds, T.B.5
-
87
-
-
77949413099
-
Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation
-
Roullet S, Pillot J, Freyburger G, et al. Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation. Br J Anaesth 2010; 104: 422-8
-
(2010)
Br J Anaesth
, vol.104
, pp. 422-428
-
-
Roullet, S.1
Pillot, J.2
Freyburger, G.3
-
88
-
-
0034655629
-
Aprotinin and transfusion requirements in orthotopic liver transplantation: A multicentre randomised double-blind study
-
EMSALT Study Group
-
Porte RJ, Molenaar IQ, Begliomini B, et al. Aprotinin and transfusion requirements in orthotopic liver transplantation: a multicentre randomised double-blind study. EMSALT Study Group. Lancet 2000; 355: 1303-9
-
(2000)
Lancet
, vol.355
, pp. 1303-1309
-
-
Porte, R.J.1
Molenaar, I.Q.2
Begliomini, B.3
-
89
-
-
0033917175
-
Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation
-
Dalmau A, Sabate A, Acosta F, et al. Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation. Anesth Analg 2000; 91: 29-34
-
(2000)
Anesth Analg
, vol.91
, pp. 29-34
-
-
Dalmau, A.1
Sabate, A.2
Acosta, F.3
-
90
-
-
1242306991
-
The prophylactic use of tranexamic acid and aprotinin in orthotopic liver transplantation: A comparative study
-
Dalmau A, Sabate A, Koo M, et al. The prophylactic use of tranexamic acid and aprotinin in orthotopic liver transplantation: a comparative study. Liver Transpl 2004; 10: 279-84
-
(2004)
Liver Transpl
, vol.10
, pp. 279-284
-
-
Dalmau, A.1
Sabate, A.2
Koo, M.3
-
91
-
-
33845651348
-
Efficacy and safety of antifibrinolytic drugs in liver transplantation: A systematic review and meta-analysis
-
Molenaar IQ, Warnaar N, Groen H, Tenvergert EM, Slooff MJ, Porte RJ. Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysis. Am J Transplant 2007; 7: 185-94
-
(2007)
Am J Transplant
, vol.7
, pp. 185-194
-
-
Molenaar, I.Q.1
Warnaar, N.2
Groen, H.3
Tenvergert, E.M.4
Slooff, M.J.5
Porte, R.J.6
-
92
-
-
79958250005
-
Aprotinin versus tranexamic acid during liver transplantation: Impact on blood product requirements and survival
-
Massicotte L, Denault AY, Beaulieu D, Thibeault L, Hevesi Z, Roy A. Aprotinin versus tranexamic acid during liver transplantation: impact on blood product requirements and survival. Transplantation 2011; 91: 1273-8
-
(2011)
Transplantation
, vol.91
, pp. 1273-1278
-
-
Massicotte, L.1
Denault, A.Y.2
Beaulieu, D.3
Thibeault, L.4
Hevesi, Z.5
Roy, A.6
-
93
-
-
33645321129
-
Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation
-
Ickx BE, van der Linden PJ, Melot C, et al. Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation. Transfusion 2006; 46: 595-605
-
(2006)
Transfusion
, vol.46
, pp. 595-605
-
-
Ickx, B.E.1
Van Der Linden, P.J.2
Melot, C.3
-
94
-
-
84856344486
-
Methods to decrease blood loss and transfusion requirements for liver transplantation
-
Gurusamy KS, Pissanou T, Pikhart H, Vaughan J, Burroughs AK, Davidson BR. Methods to decrease blood loss and transfusion requirements for liver transplantation. Cochrane Database Syst Rev 2011; 12: CD009052
-
(2011)
Cochrane Database Syst Rev
, vol.12
-
-
Gurusamy, K.S.1
Pissanou, T.2
Pikhart, H.3
Vaughan, J.4
Burroughs, A.K.5
Davidson, B.R.6
-
95
-
-
68349131341
-
Aprotinin and the risk of thromboticcomplicationsafter liver transplantation:A retrospective analysis of 1492 patients
-
Warnaar N, Mallett SV, Klinck JR, et al. Aprotinin and the risk of thromboticcomplicationsafter liver transplantation:a retrospective analysis of 1492 patients. Liver Transpl 2009; 15: 747-53
-
(2009)
Liver Transpl
, vol.15
, pp. 747-753
-
-
Warnaar, N.1
Mallett, S.V.2
Klinck, J.R.3
-
96
-
-
79953218118
-
The use of thromboelastometry in the assessment of hemostasis during orthotopic liver transplantation reduces the demand for blood products
-
Trzebicki J, Flakiewicz E, Kosieradzki M, et al. The use of thromboelastometry in the assessment of hemostasis during orthotopic liver transplantation reduces the demand for blood products. Ann Transplant 2010; 15: 19-24
-
(2010)
Ann Transplant
, vol.15
, pp. 19-24
-
-
Trzebicki, J.1
Flakiewicz, E.2
Kosieradzki, M.3
-
97
-
-
33749055499
-
Coagulation management during liver transplantation
-
Gorlinger K. Coagulation management during liver transplantation. Hamostaseologie 2006; 26: S64-76
-
(2006)
Hamostaseologie
, vol.26
-
-
Gorlinger, K.1
-
98
-
-
31844435169
-
Perioperative parenteral tranexamic acid in liver tumor resection: A prospective randomized trial toward a "blood transfusion" free hepatectomy
-
Wu CC,Ho WM,Cheng SB, et al.Perioperative parenteral tranexamic acid in liver tumor resection: a prospective randomized trial toward a "blood transfusion"-free hepatectomy. Ann Surg 2006; 243: 173-80
-
(2006)
Ann Surg
, vol.243
, pp. 173-180
-
-
Wu, C.C.1
Ho, W.M.2
Cheng, S.B.3
-
99
-
-
33748957178
-
Maternal mortality: Who, when, where, and why
-
Ronsmans C, GrahamWJ. Maternal mortality: who, when, where, and why. Lancet 2006; 368: 1189-200
-
(2006)
Lancet
, vol.368
, pp. 1189-1200
-
-
Ronsmans, C.1
Graham, W.J.2
-
100
-
-
79952504686
-
Saving mothers' lives: Reviewing maternal deaths to make motherhood safer: 2006-2008
-
Theeighth report of theconfidential enquiries intomaternal deaths in the United Kingdom
-
Cantwell R, Clutton-Brock T, Cooper G, et al. Saving mothers' lives: reviewing maternal deaths to make motherhood safer: 2006- 2008.Theeighth report of theconfidential enquiries intomaternal deaths in the United Kingdom. BJOG 2011; 118 (Suppl. 1): 1-203
-
(2011)
BJOG
, vol.118
, Issue.SUPPL.1
, pp. 1-203
-
-
Cantwell, R.1
Clutton-Brock, T.2
Cooper, G.3
-
101
-
-
1642463932
-
Clinical observation of blood loss reduced by tranexamic acid during and after caesarean section: A multi-center, randomized trial
-
Gai MY, Wu LF, Su QF, Tatsumoto K. Clinical observation of blood loss reduced by tranexamic acid during and after caesarean section: a multi-center, randomized trial. Eur J Obstet Gynecol Reprod Biol 2004; 112: 154-7
-
(2004)
Eur J Obstet Gynecol Reprod Biol
, vol.112
, pp. 154-157
-
-
Gai, M.Y.1
Wu, L.F.2
Su, Q.F.3
Tatsumoto, K.4
-
102
-
-
68949206483
-
Antifibrinolytic agents in post partum haemorrhage: A systematic review
-
Ferrer P, Roberts I, Sydenham E, Blackhall K, Shakur H. Antifibrinolytic agents in post partum haemorrhage: a systematic review. BMC Pregnancy Childbirth 2009; 9: 29
-
(2009)
BMC Pregnancy Childbirth
, vol.9
, pp. 29
-
-
Ferrer, P.1
Roberts, I.2
Sydenham, E.3
Blackhall, K.4
Shakur, H.5
-
103
-
-
61649121391
-
Efficacy of tranexamic acid in decreasing blood loss during and after cesarean section: A randomized case controlled prospective study
-
Gohel M, Patel P, Ashoo G, Desai P. Efficacy of tranexamic acid in decreasing blood loss during and after cesarean section: a randomized case controlled prospective study. J Obstet Gynaecol India 2007; 57: 227-30
-
(2007)
J Obstet Gynaecol India
, vol.57
, pp. 227-230
-
-
Gohel, M.1
Patel, P.2
Ashoo, G.3
Desai, P.4
-
104
-
-
1642470423
-
Clinical study on the efficacy of tranexamic acid in reducing postpartum blood loss: A randomized comparative multicenter trial
-
Yang H, Zheng S, Shi C. Clinical study on the efficacy of tranexamic acid in reducing postpartum blood loss: a randomized, comparative, multicenter trial.Zhonghua Fu Chan Ke Za Zhi 2001;36:590-2
-
(2001)
Zhonghua Fu Chan Ke Za Zhi
, vol.36
, pp. 590-592
-
-
Yang, H.1
Zheng, S.2
Shi, C.3
-
106
-
-
79955076605
-
High-dose tranexamic acid reduces blood loss in postpartum haemorrhage
-
Ducloy-Bouthors AS, Jude B, Duhamel A, et al. High-dose tranexamic acid reduces blood loss in postpartum haemorrhage. Critical Care 2011; 15: R117
-
(2011)
Critical Care
, vol.15
-
-
Ducloy-Bouthors, A.S.1
Jude, B.2
Duhamel, A.3
-
107
-
-
79952311766
-
Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: A prospective, randomized, double-blind, placebo-controlled study
-
Gungorduk K, Yildirim G, Asicioglu O, Gungorduk OC, Sudolmus S, Ark C. Efficacy of intravenous tranexamic acid in reducing blood loss after elective cesarean section: a prospective, randomized, double-blind, placebo-controlled study. Am J Perinatol 2011; 28: 233-40
-
(2011)
Am J Perinatol
, vol.28
, pp. 233-240
-
-
Gungorduk, K.1
Yildirim, G.2
Asicioglu, O.3
Gungorduk, O.C.4
Sudolmus, S.5
Ark, C.6
-
108
-
-
77952605810
-
The WOMAN Trial (World Maternal Antifibrinolytic Trial): Tranexamic acid for the treatment of postpartum haemorrhage: An international randomised, double blind placebo controlled trial
-
Shakur H, Elbourne D, Gulmezoglu M, et al. The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial. Trials 2010; 11: 40
-
(2010)
Trials
, vol.11
, pp. 40
-
-
Shakur, H.1
Elbourne, D.2
Gulmezoglu, M.3
-
109
-
-
0023199110
-
The risk of rebleeding from ruptured intracranial aneurysms
-
Rosenorn J, Eskesen V, Schmidt K, Ronde F. The risk of rebleeding from ruptured intracranial aneurysms. J Neurosurg 1987; 67: 329-32
-
(1987)
J Neurosurg
, vol.67
, pp. 329-332
-
-
Rosenorn, J.1
Eskesen, V.2
Schmidt, K.3
Ronde, F.4
-
110
-
-
84855891431
-
Rebleeding after aneurysmal subarachnoid hemorrhage
-
Starke RM, Connolly ES Jr. Rebleeding after aneurysmal subarachnoid hemorrhage. Neurocritical Care 2011; 15: 241-6
-
(2011)
Neurocritical Care
, vol.15
, pp. 241-246
-
-
Starke, R.M.1
Connolly, Jr.E.S.2
-
111
-
-
84893373135
-
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage
-
Roos YB, Rinkel GJ,VermeulenM, AlgraA, vanGijn J. Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev 2003; 2: CD001245
-
(2003)
Cochrane Database Syst Rev
, vol.2
-
-
Roos, Y.B.1
Rinkel, G.J.2
Vermeulen, M.3
Algra, A.4
Van Gijn, J.5
-
112
-
-
0033962206
-
Antifibrinolytic treatment in subarachnoid hemorrhage: A randomizedplacebo-controlled trial.STAR study group
-
Roos Y. Antifibrinolytic treatment in subarachnoid hemorrhage: a randomizedplacebo-controlled trial.STARStudyGroup.Neurology 2000; 54: 77-82
-
(2000)
Neurology
, vol.54
, pp. 77-82
-
-
Roos, Y.1
-
113
-
-
0036801577
-
Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: A prospective randomized study
-
Hillman J, Fridriksson S, Nilsson O, Yu Z, Saveland H, Jakobsson KE. Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study. J Neurosurg 2002; 97: 771-8
-
(2002)
J Neurosurg
, vol.97
, pp. 771-778
-
-
Hillman, J.1
Fridriksson, S.2
Nilsson, O.3
Yu, Z.4
Saveland, H.5
Jakobsson, K.E.6
-
114
-
-
52449109704
-
Impact of a protocol for acute antifibrinolytic therapy on aneurysm rebleeding after subarachnoid hemorrhage
-
Starke RM, Kim GH, Fernandez A, et al. Impact of a protocol for acute antifibrinolytic therapy on aneurysm rebleeding after subarachnoid hemorrhage. Stroke 2008; 39: 2617-21
-
(2008)
Stroke
, vol.39
, pp. 2617-2621
-
-
Starke, R.M.1
Kim, G.H.2
Fernandez, A.3
-
115
-
-
77957988787
-
Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: Effects on rehemorrhage, cerebral ischemia, andhydrocephalus
-
935-9 discussion
-
Harrigan MR, Rajneesh KF, Ardelt AA, FisherWS III. Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, andhydrocephalus. Neurosurgery 2010; 67: 935-9; discussion 9-40
-
(2010)
Neurosurgery
, vol.67
, pp. 9-40
-
-
Harrigan, M.R.1
Rajneesh, K.F.2
Ardelt, A.A.3
Fisher III, W.S.4
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