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Volumn 14, Issue 4, 2010, Pages

Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: A retrospective analysis

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; BIOLOGICAL MARKER; CREATINE KINASE; CREATINE KINASE ISOENZYME; FRESH FROZEN PLASMA; THROMBOCYTE CONCENTRATE; TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

EID: 77955117750     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9216     Document Type: Article
Times cited : (91)

References (30)
  • 1
    • 31344467254 scopus 로고    scopus 로고
    • The risk associated with aprotinin in cardiac surgery
    • 10.1056/NEJMoa051379, 16436767, Group MSoPIR, Foundation IRaE
    • Mangano D, Tudor IC, Dietzel C, . Group MSoPIR, Foundation IRaE The risk associated with aprotinin in cardiac surgery. N Engl J Med 2006, 354:353-365. 10.1056/NEJMoa051379, 16436767, Group MSoPIR, Foundation IRaE.
    • (2006) N Engl J Med , vol.354 , pp. 353-365
    • Mangano, D.1    Tudor, I.C.2    Dietzel, C.3
  • 2
    • 33846885901 scopus 로고    scopus 로고
    • Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery
    • 10.1001/jama.297.5.471, 17284697, Group IoTMSoPIR, Foundation IRaE
    • Mangano D, Miao Y, Vuylsteke A, Tudor IC, Juneja R, Filipescu D, Hoeft A, Fontes ML, Hillel Z, Ott E, Titov T, Dietzel C, Levin J, . Group IoTMSoPIR, Foundation IRaE Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery. JAMA 2007, 297:471-479. 10.1001/jama.297.5.471, 17284697, Group IoTMSoPIR, Foundation IRaE.
    • (2007) JAMA , vol.297 , pp. 471-479
    • Mangano, D.1    Miao, Y.2    Vuylsteke, A.3    Tudor, I.C.4    Juneja, R.5    Filipescu, D.6    Hoeft, A.7    Fontes, M.L.8    Hillel, Z.9    Ott, E.10    Titov, T.11    Dietzel, C.12    Levin, J.13
  • 3
    • 33644680067 scopus 로고    scopus 로고
    • A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery
    • 10.1111/j.1537-2995.2006.00724.x, 16533273
    • Karkouti K, Beattie WS, Dattilo KM, McCluskey SA, Ghannam M, Hamdy A, Wijeysundera DN, Fedorko L, Yau TM. A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery. Transfusion 2006, 46:327-338. 10.1111/j.1537-2995.2006.00724.x, 16533273.
    • (2006) Transfusion , vol.46 , pp. 327-338
    • Karkouti, K.1    Beattie, W.S.2    Dattilo, K.M.3    McCluskey, S.A.4    Ghannam, M.5    Hamdy, A.6    Wijeysundera, D.N.7    Fedorko, L.8    Yau, T.M.9
  • 5
    • 39549100109 scopus 로고    scopus 로고
    • Aprotinin during coronary-artery bypass grafting and risk of death
    • 10.1056/NEJMoa0707571, 18287600
    • Schneeweiss S, Seeger JD, Landon J, Walker AM. Aprotinin during coronary-artery bypass grafting and risk of death. N Engl J Med 2008, 358:771-783. 10.1056/NEJMoa0707571, 18287600.
    • (2008) N Engl J Med , vol.358 , pp. 771-783
    • Schneeweiss, S.1    Seeger, J.D.2    Landon, J.3    Walker, A.M.4
  • 7
    • 58149293358 scopus 로고    scopus 로고
    • The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients
    • 10.1213/ane.0b013e318184bc20, 19020118
    • Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients. Anesth Analg 2008, 107:1783-1790. 10.1213/ane.0b013e318184bc20, 19020118.
    • (2008) Anesth Analg , vol.107 , pp. 1783-1790
    • Martin, K.1    Wiesner, G.2    Breuer, T.3    Lange, R.4    Tassani, P.5
  • 8
    • 57549085150 scopus 로고    scopus 로고
    • The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery
    • author reply, 171, 10.1016/j.ejcts.2008.09.038, 19027313
    • Breuer T, Martin K, Wilhelm M, Wiesner G, Schreiber C, Hess J, Lange R, Tassani P. The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery. Eur J Cardiothorac Surg 2009, 35:167-171. author reply, 171, 10.1016/j.ejcts.2008.09.038, 19027313.
    • (2009) Eur J Cardiothorac Surg , vol.35 , pp. 167-171
    • Breuer, T.1    Martin, K.2    Wilhelm, M.3    Wiesner, G.4    Schreiber, C.5    Hess, J.6    Lange, R.7    Tassani, P.8
  • 9
    • 76249100902 scopus 로고    scopus 로고
    • High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients
    • 10.1213/ANE.0b013e3181c92b23, 19996135
    • Murkin JM, Falter F, Granton J, Young B, Burt C, Chu M. High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients. Anesth Analg 2010, 110:350-353. 10.1213/ANE.0b013e3181c92b23, 19996135.
    • (2010) Anesth Analg , vol.110 , pp. 350-353
    • Murkin, J.M.1    Falter, F.2    Granton, J.3    Young, B.4    Burt, C.5    Chu, M.6
  • 10
    • 74049141396 scopus 로고    scopus 로고
    • The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery
    • 10.1213/ANE.0b013e3181c0ea6d, 19910626
    • Karkouti K, Wijeysundera DN, Yau TM, McCluskey SA, Tait G, Beattie WS. The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. Anesth Analg 2010, 110:21-29. 10.1213/ANE.0b013e3181c0ea6d, 19910626.
    • (2010) Anesth Analg , vol.110 , pp. 21-29
    • Karkouti, K.1    Wijeysundera, D.N.2    Yau, T.M.3    McCluskey, S.A.4    Tait, G.5    Beattie, W.S.6
  • 13
    • 26844576373 scopus 로고    scopus 로고
    • Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials
    • 10.1186/1471-2261-5-19, 1185524, 15992412
    • Carless PA, Moxey AJ, Stokes BJ, Henry DA. Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials. BMC Cardiovasc Disord 2005, 5:19. 10.1186/1471-2261-5-19, 1185524, 15992412.
    • (2005) BMC Cardiovasc Disord , vol.5 , pp. 19
    • Carless, P.A.1    Moxey, A.J.2    Stokes, B.J.3    Henry, D.A.4
  • 14
    • 56149094734 scopus 로고    scopus 로고
    • Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin
    • 10.1213/ane.0b013e318182252b, 18931201
    • Dietrich W, Spannagl M, Boehm J, Hauner K, Braun S, Schuster T, Busley R. Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin. Anesth Analg 2008, 107:1469-1478. 10.1213/ane.0b013e318182252b, 18931201.
    • (2008) Anesth Analg , vol.107 , pp. 1469-1478
    • Dietrich, W.1    Spannagl, M.2    Boehm, J.3    Hauner, K.4    Braun, S.5    Schuster, T.6    Busley, R.7
  • 17
    • 0037772629 scopus 로고    scopus 로고
    • About dosage schemes and safety of tranexamic acid in cardiac surgery
    • author reply, 236, 10.1097/00000542-200307000-00039, 12826869
    • Casati V. About dosage schemes and safety of tranexamic acid in cardiac surgery. Anesthesiology 2003, 99:236. author reply, 236, 10.1097/00000542-200307000-00039, 12826869.
    • (2003) Anesthesiology , vol.99 , pp. 236
    • Casati, V.1
  • 18
    • 0033662348 scopus 로고    scopus 로고
    • Convulsive seizures following subdural application of fibrin sealant containing tranexamic acid in a rat model
    • 10.1097/00006123-200012000-00048, 11126922
    • Schlag MG, Hopf R, Redl H. Convulsive seizures following subdural application of fibrin sealant containing tranexamic acid in a rat model. Neurosurgery 2000, 47:1463-1467. 10.1097/00006123-200012000-00048, 11126922.
    • (2000) Neurosurgery , vol.47 , pp. 1463-1467
    • Schlag, M.G.1    Hopf, R.2    Redl, H.3
  • 19
    • 0036164926 scopus 로고    scopus 로고
    • Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats
    • 10.1007/s701-002-8275-z, 11807648
    • Schlag MG, Hopf R, Zifko U, Redl H. Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats. Acta Neurochir (Wien) 2002, 144:63-69. 10.1007/s701-002-8275-z, 11807648.
    • (2002) Acta Neurochir (Wien) , vol.144 , pp. 63-69
    • Schlag, M.G.1    Hopf, R.2    Zifko, U.3    Redl, H.4
  • 20
    • 0037219816 scopus 로고    scopus 로고
    • Convulsions and refractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid
    • 10.1097/00000542-200301000-00042, 12503009
    • Yeh HM, Lau HP, Lin PL, Sun WZ, Mok MS. Convulsions and refractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid. Anesthesiology 2003, 98:270-272. 10.1097/00000542-200301000-00042, 12503009.
    • (2003) Anesthesiology , vol.98 , pp. 270-272
    • Yeh, H.M.1    Lau, H.P.2    Lin, P.L.3    Sun, W.Z.4    Mok, M.S.5
  • 21
    • 0036196828 scopus 로고    scopus 로고
    • Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect
    • 10.1124/jpet.301.1.168, 11907171
    • Furtmüller R, Schlag MG, Berger M, Hopf R, Huck S, Sieghart W, Redl H. Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. J Pharmacol Exp Ther 2002, 301:168-173. 10.1124/jpet.301.1.168, 11907171.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 168-173
    • Furtmüller, R.1    Schlag, M.G.2    Berger, M.3    Hopf, R.4    Huck, S.5    Sieghart, W.6    Redl, H.7
  • 24
    • 0027232602 scopus 로고
    • Renal dysfunction and intravascular coagulation with aprotinin and hypothermic circulatory arrest
    • 10.1016/0003-4975(93)91082-X, 7685587
    • Sundt TM, Kouchoukos NT, Saffitz JE, Murphy SF, Wareing TH, Stahl DJ. Renal dysfunction and intravascular coagulation with aprotinin and hypothermic circulatory arrest. Ann Thorac Surg 1993, 55:1418-1424. 10.1016/0003-4975(93)91082-X, 7685587.
    • (1993) Ann Thorac Surg , vol.55 , pp. 1418-1424
    • Sundt, T.M.1    Kouchoukos, N.T.2    Saffitz, J.E.3    Murphy, S.F.4    Wareing, T.H.5    Stahl, D.J.6
  • 25
    • 34249913425 scopus 로고    scopus 로고
    • Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery
    • 10.1161/CIRCULATIONAHA.106.671222, 17533182
    • Brown JR, Birkmeyer NJ, O'Connor GT. Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery. Circulation 2007, 115:2801-2813. 10.1161/CIRCULATIONAHA.106.671222, 17533182.
    • (2007) Circulation , vol.115 , pp. 2801-2813
    • Brown, J.R.1    Birkmeyer, N.J.2    O'Connor, G.T.3
  • 26
  • 28
    • 4444380033 scopus 로고    scopus 로고
    • Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials
    • 10.1016/j.jtcvs.2004.03.041, 15354106
    • Sedrakyan A, Treasure T, Elefteriades JA. Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials. J Thorac Cardiovasc Surg 2004, 128:442-448. 10.1016/j.jtcvs.2004.03.041, 15354106.
    • (2004) J Thorac Cardiovasc Surg , vol.128 , pp. 442-448
    • Sedrakyan, A.1    Treasure, T.2    Elefteriades, J.A.3
  • 29
    • 0023204701 scopus 로고
    • Effect of aprotinin on need for blood transfusion after repeat open-heart surgery
    • 10.1016/S0140-6736(87)91190-1, 2446091
    • Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. Lancet 1987, 2:1289-1291. 10.1016/S0140-6736(87)91190-1, 2446091.
    • (1987) Lancet , vol.2 , pp. 1289-1291
    • Royston, D.1    Bidstrup, B.P.2    Taylor, K.M.3    Sapsford, R.N.4
  • 30
    • 62249196771 scopus 로고    scopus 로고
    • Aprotinin: 1 year on
    • 10.1097/ACO.0b013e32831c833f, 19295302
    • Dietrich W. Aprotinin: 1 year on. Curr Opin Anaesthesiol 2009, 22:121-127. 10.1097/ACO.0b013e32831c833f, 19295302.
    • (2009) Curr Opin Anaesthesiol , vol.22 , pp. 121-127
    • Dietrich, W.1


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