Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 12, 2013, Pages 2858-2866

  Renault, Marie Ange ^a,b   Robbesyn, Fanny ^a,b   Chapouly, Candice ^a,b,c   Yao, Qinyu ^a,b   Vandierdonck, Soizic ^a,b,c   Reynaud, Annabel ^a,b   Belloc, Isabelle ^a,b   Traiffort, Elisabeth ^d   Ruat, Martial ^d   Desgranges, Claude ^a,b   Gadeau, Alain Pierre ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b Bordeaux Segalen University   (France)

^c BORDEAUX UNIVERSITY HOSPITAL   (France)

^d CNRS   (France)

Author keywords

Aging; Angiogenesis effect; Angiogenesis, pathological; Hedgehogs; Peripheral arterial disease; Regeneration

Indexed keywords

MESSENGER RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

AGED; ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENE THERAPY; HAPLOINSUFFICIENCY; LEG ISCHEMIA; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIBIALIS ANTERIOR MUSCLE; UPREGULATION;

AGING; ANGIOGENESIS EFFECT; ANGIOGENESIS, PATHOLOGICAL; HEDGEHOGS; PERIPHERAL ARTERIAL DISEASE; REGENERATION;

AGE FACTORS; AGING; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENETIC THERAPY; HEDGEHOG PROTEINS; HINDLIMB; IMMUNOGLOBULIN G; ISCHEMIA; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; REGENERATION; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84888204058     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.302494     Document Type: Article

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