Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing

Mechanisms of Ageing and Development

Volumn 134, Issue 10, 2013, Pages 478-485

  Han, Jeehae ^a   Ryu, Seungjin ^a   Moskowitz, David M ^b   Rothenberg, Devorah ^a   Leahy, Daniel J ^c   Atzmon, Gil ^a   Barzilai, Nir ^a   Suh, Yousin ^a,d  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Candidate genes; Centenarian; Functional variant; Human longevity; Target capture and next generation sequencing

Indexed keywords

APOE GENE; ARTICLE; COGNITION; GENE; GENE DELETION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; LONGEVITY; MAJOR CLINICAL STUDY; NERVE DEGENERATION; PILOT STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY;

CANDIDATE GENES; CENTENARIAN; FUNCTIONAL VARIANT; HUMAN LONGEVITY; TARGET CAPTURE AND NEXT-GENERATION SEQUENCING;

AGED, 80 AND OVER; FEMALE; GENOTYPE; HUMANS; LONGEVITY; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 84888132534     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2013.01.005     Document Type: Article

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