Gene expression analysis of mTOR pathway: Association with human longevity

Aging Cell

Volumn 12, Issue 1, 2013, Pages 24-31

  Passtoors, Willemijn M ^a   Beekman, Marian ^a,b   Deelen, Joris ^a,b   van der Breggen, Ruud ^a   Maier, Andrea B ^a   Guigas, Bruno ^a   Derhovanessian, Evelyna ^c   van Heemst, Diana ^a   de Craen, Anton J M ^a   Gunn, David A ^d   Pawelec, Graham ^c   Slagboom, Pieternella E ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Consortium for Healthy Ageing   (Netherlands)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNILEVER RESEARCH   (United Kingdom)

Author keywords

Aging; Gene expression; Human; Longevity; MTOR

Indexed keywords

AMINO ACID; GLUCOSE; GROWTH FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 4B; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; PROTEIN P14; PROTEIN P18; RHEB PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; S6 KINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR YY1; TUBERIN; VASCULOTROPIN; WNT PROTEIN;

AGED; AGING; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOGENESIS; BLOOD SAMPLING; COHORT ANALYSIS; CONTROLLED STUDY; CYTOSKELETON; DNA DAMAGE; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HEREDITY; HUMAN; HYPOXIA; LIPOGENESIS; LONGEVITY; MALE; METABOLISM; MITOCHONDRION; MORBIDITY; NEOPLASM; NETHERLANDS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROGENY; RIBOSOME; RNA TRANSLATION; SENESCENCE; SIGNAL TRANSDUCTION; SURVIVAL;

AGED, 80 AND OVER; AGING; GENE EXPRESSION; HUMANS; LONGEVITY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

ANIMALIA; RAPTORES;

EID: 84872620350     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12015     Document Type: Article

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