-
1
-
-
33846531356
-
The tumour microenvironment as a target for chemoprevention
-
Albini, A.; Sporn, M. B. The tumour microenvironment as a target for chemoprevention. Nat. Rev. Cancer 2007, 7 (2), 139-147.
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.2
, pp. 139-147
-
-
Albini, A.1
Sporn, M.B.2
-
2
-
-
78651073833
-
The role of tumor stroma in cancer progression and prognosis: Emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer
-
Bremnes, R. M.; Donnem, T.; Al-Saad, S.; Al-Shibli, K.; Andersen, S.; Sirera, R.; Camps, C.; Marinez, I.; Busund, L. T. The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer. J. Thorac. Oncol. 2011, 6 (1), 209-217.
-
(2011)
J. Thorac. Oncol
, vol.6
, Issue.1
, pp. 209-217
-
-
Bremnes, R.M.1
Donnem, T.2
Al-Saad, S.3
Al-Shibli, K.4
Andersen, S.5
Sirera, R.6
Camps, C.7
Marinez, I.8
Busund, L.T.9
-
3
-
-
8144228952
-
Friends or foes - bipolar effects of the tumour stroma in cancer
-
Mueller, M. M.; Fusenig, N. E. Friends or foes - bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 2004, 4 (11), 839-849.
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.11
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
4
-
-
20444412646
-
Therapeutic targeting of the tumor microenvironment
-
Joyce, J. A. Therapeutic targeting of the tumor microenvironment. Cancer Cell 2005, 7(6), 513-520.
-
(2005)
Cancer Cell
, vol.7
, Issue.6
, pp. 513-520
-
-
Joyce, J.A.1
-
5
-
-
79955870488
-
Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer
-
Schauer, I. G.; Sood, A. K.; Mok, S.; Liu, J. Cancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer. Neoplasia 2011, 13 (5), 393-405.
-
(2011)
Neoplasia
, vol.13
, Issue.5
, pp. 393-405
-
-
Schauer, I.G.1
Sood, A.K.2
Mok, S.3
Liu, J.4
-
6
-
-
84861186736
-
Jekyll and Hyde: The role of the microenvironment on the progression of cancer
-
Allen, M.; Louise Jones, J. Jekyll and Hyde: the role of the microenvironment on the progression of cancer. J. Pathol. 2011, 223(2), 162-176.
-
(2011)
J. Pathol
, vol.223
, Issue.2
, pp. 162-176
-
-
Allen, M.1
Louise Jones, J.2
-
7
-
-
33749434794
-
Contact stimulation of fibroblasts for tenascin production by melanoma cells
-
Adam, B.; Toth, L.; Pasti, G.; Balazs, M.; Adany, R. Contact stimulation of fibroblasts for tenascin production by melanoma cells. Melanoma Res. 2006, 16 (5), 385-391.
-
(2006)
Melanoma Res
, vol.16
, Issue.5
, pp. 385-391
-
-
Adam, B.1
Toth, L.2
Pasti, G.3
Balazs, M.4
Adany, R.5
-
8
-
-
77956280130
-
Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness
-
Giannoni, E.; Bianchini, F.; Masieri, L.; Serni, S.; Torre, E.; Calorini, L.; Chiarugi, P. Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res. 2010, 70(17), 6945-6956.
-
(2010)
Cancer Res
, vol.70
, Issue.17
, pp. 6945-6956
-
-
Giannoni, E.1
Bianchini, F.2
Masieri, L.3
Serni, S.4
Torre, E.5
Calorini, L.6
Chiarugi, P.7
-
9
-
-
1042279670
-
Population pharmacokinetics of sibrotuzumab, a novel therapeutic monoclonal antibody, in cancer patients
-
Kloft, C.; Graefe, E. U.; Tanswell, P.; Scott, A. M.; Hofheinz, R.; Amelsberg, A.; Karlsson, M. O. Population pharmacokinetics of sibrotuzumab, a novel therapeutic monoclonal antibody, in cancer patients. Invest. New Drugs 2004, 22 (1), 39-52.
-
(2004)
Invest. New Drugs
, vol.22
, Issue.1
, pp. 39-52
-
-
Kloft, C.1
Graefe, E.U.2
Tanswell, P.3
Scott, A.M.4
Hofheinz, R.5
Amelsberg, A.6
Karlsson, M.O.7
-
10
-
-
0037989982
-
A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer
-
Scott, A. M.; Wiseman, G.; Welt, S.; Adjei, A.; Lee, F. T.; Hopkins, W.; Divgi, C. R.; Hanson, L. H.; Mitchell, P.; Gansen, D. N.; Larson, S. M.; Ingle, J. N.; Hoffman, E. W.; Tanswell, P.; Ritter, G.; Cohen, L. S.; Bette, P.; Arvay, L.; Amelsberg, A.; Vlock, D.; Rettig, W. J.; Old, L. J. A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clin. Cancer Res. 2003, 9 (5), 1639-1647.
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.5
, pp. 1639-1647
-
-
Scott, A.M.1
Wiseman, G.2
Welt, S.3
Adjei, A.4
Lee, F.T.5
Hopkins, W.6
Divgi, C.R.7
Hanson, L.H.8
Mitchell, P.9
Gansen, D.N.10
Larson, S.M.11
Ingle, J.N.12
Hoffman, E.W.13
Tanswell, P.14
Ritter, G.15
Cohen, L.S.16
Bette, P.17
Arvay, L.18
Amelsberg, A.19
Vlock, D.20
Rettig, W.J.21
Old, L.J.22
more..
-
11
-
-
0037219532
-
Stromal antigen targeting by a humanised monoclonal antibody: An early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer
-
Hofheinz, R. D.; al-Batran, S. E.; Hartmann, F.; Hartung, G.; Jager, D.; Renner, C.; Tanswell, P.; Kunz, U.; Amelsberg, A.; Kuthan, H.; Stehle, G. Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer. Onkologie 2003, 26 (1), 44-48.
-
(2003)
Onkologie
, vol.26
, Issue.1
, pp. 44-48
-
-
Hofheinz, R.D.1
Al-Batran, S.E.2
Hartmann, F.3
Hartung, G.4
Jager, D.5
Renner, C.6
Tanswell, P.7
Kunz, U.8
Amelsberg, A.9
Kuthan, H.10
Stehle, G.11
-
12
-
-
1342287074
-
Novel angiogenic signaling pathways and vascular targets
-
Bicknell, R.; Harris, A. L. Novel angiogenic signaling pathways and vascular targets. Annu.Rev. Pharmacol. Toxicol. 2004, 44 219-238.
-
(2004)
Annu.Rev. Pharmacol. Toxicol
, vol.44
, pp. 219-238
-
-
Bicknell, R.1
Harris, A.L.2
-
13
-
-
0035866779
-
Angiogenesis and prostate cancer: Identification of a molecular progression switch
-
Huss, W. J.; Hanrahan, C. F.; Barrios, R. J.; Simons, J. W.; Greenberg, N. M. Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res. 2001, 61 (6), 2736-2743.
-
(2001)
Cancer Res
, vol.61
, Issue.6
, pp. 2736-2743
-
-
Huss, W.J.1
Hanrahan, C.F.2
Barrios, R.J.3
Simons, J.W.4
Greenberg, N.M.5
-
14
-
-
49349086143
-
Circulating endothelial cells as biomarkers of prostate cancer
-
Georgiou, H. D.; Namdarian, B.; Corcoran, N. M.; Costello, A. J.; Hovens, C. M. Circulating endothelial cells as biomarkers of prostate cancer. Nat. Clin. Pract. Urol. 2008, 5 (8), 445-454.
-
(2008)
Nat. Clin. Pract. Urol
, vol.5
, Issue.8
, pp. 445-454
-
-
Georgiou, H.D.1
Namdarian, B.2
Corcoran, N.M.3
Costello, A.J.4
Hovens, C.M.5
-
15
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet, P.; Jain, R. K. Angiogenesis in cancer and other diseases. Nature 2000, 407 (6801), 249-257.
-
(2000)
Nature
, vol.407
, Issue.6801
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
16
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman, J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 1971, 285 (21), 1182-1186.
-
(1971)
N. Engl. J. Med
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
17
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman, J. Angiogenesis: an organizing principle for drug discovery? Nat.Rev. Drug Discov. 2007, 6 (4), 273-286.
-
(2007)
Nat.Rev. Drug Discov
, vol.6
, Issue.4
, pp. 273-286
-
-
Folkman, J.1
-
18
-
-
32944463899
-
Angiogenesis
-
Folkman, J. Angiogenesis. Annu. Rev. Med. 2006, 57, 1-18.
-
(2006)
Annu. Rev. Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
19
-
-
77954668887
-
Angiogenesis inhibitors: Current strategies and future prospects
-
Cook, K. M.; Figg, W. D. Angiogenesis inhibitors: current strategies and future prospects. CA Cancer J. Clin. 2010, 60 (4), 222-243.
-
(2010)
CA Cancer J. Clin
, vol.60
, Issue.4
, pp. 222-243
-
-
Cook, K.M.1
Figg, W.D.2
-
20
-
-
80052047659
-
Recent advances in anti-angiogenic therapy of cancer
-
Samant, R. S.; Shevde, L. A. Recent advances in anti-angiogenic therapy of cancer. Oncotarget. 2011, 2 (3), 122-134.
-
(2011)
Oncotarget
, vol.2
, Issue.3
, pp. 122-134
-
-
Samant, R.S.1
Shevde, L.A.2
-
21
-
-
80855130388
-
Systemic therapy for advanced gastrointestinal stromal tumors: Beyond imatinib
-
Kim, E. J.; Zalupski, M. M. Systemic therapy for advanced gastrointestinal stromal tumors: beyond imatinib. J. Surg. Oncol. 2011, 104 (8), 901-906.
-
(2011)
J. Surg. Oncol
, vol.104
, Issue.8
, pp. 901-906
-
-
Kim, E.J.1
Zalupski, M.M.2
-
22
-
-
80051736592
-
Cost-effectiveness of sunitinib in metastatic renal cell carcinoma
-
Purmonen, T. T. Cost-effectiveness of sunitinib in metastatic renal cell carcinoma. Expert Rev. Pharmacoecon Outcomes Res. 2011, 11 (4), 383-393.
-
(2011)
Expert Rev. Pharmacoecon Outcomes Res
, vol.11
, Issue.4
, pp. 383-393
-
-
Purmonen, T.T.1
-
23
-
-
0035911221
-
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
-
Lin, E. Y.; Nguyen, A. V.; Russell, R. G.; Pollard, J. W. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J. Exp. Med. 2001, 193 (6), 727-740.
-
(2001)
J. Exp. Med
, vol.193
, Issue.6
, pp. 727-740
-
-
Lin, E.Y.1
Nguyen, A.V.2
Russell, R.G.3
Pollard, J.W.4
-
24
-
-
80054075147
-
Tumour macrophages as potential targets of bisphosphonates
-
Rogers, T. L.; Holen, I. Tumour macrophages as potential targets of bisphosphonates. J. Transl. Med. 2011, 9, 177.
-
(2011)
J. Transl. Med
, vol.9
, pp. 177
-
-
Rogers, T.L.1
Holen, I.2
-
25
-
-
40049088602
-
The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages
-
Allavena, P.; Sica, A.; Solinas, G.; Porta, C.; Mantovani, A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit. Rev. Oncol. Hematol. 2008, 66 (1), 1-9.
-
(2008)
Crit. Rev. Oncol. Hematol
, vol.66
, Issue.1
, pp. 1-9
-
-
Allavena, P.1
Sica, A.2
Solinas, G.3
Porta, C.4
Mantovani, A.5
-
26
-
-
34548864683
-
Targeting tumour-associated macrophages
-
Sica, A.; Rubino, L.; Mancino, A.; Larghi, P.; Porta, C.; Rimoldi, M.; Solinas, G.; Locati, M.; Allavena, P.; Mantovani, A. Targeting tumour-associated macrophages. Expert Opin. Ther. Targets 2007, 11 (9), 1219-1229.
-
(2007)
Expert Opin. Ther. Targets
, vol.11
, Issue.9
, pp. 1219-1229
-
-
Sica, A.1
Rubino, L.2
Mancino, A.3
Larghi, P.4
Porta, C.5
Rimoldi, M.6
Solinas, G.7
Locati, M.8
Allavena, P.9
Mantovani, A.10
-
27
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
Bingle, L.; Brown, N. J.; Lewis, C. E. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 2002, 196 (3), 254-265.
-
(2002)
J. Pathol
, vol.196
, Issue.3
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
28
-
-
80053994835
-
Aspirin and cancer: Has aspirin been overlooked as an adjuvant therapy?
-
Langley, R. E.; Burdett, S.; Tierney, J. F.; Cafferty, F.; Parmar, M. K.; Venning, G. Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy? Br. J. Cancer 2011, 105 (8), 1107-1113.
-
(2011)
Br. J. Cancer
, vol.105
, Issue.8
, pp. 1107-1113
-
-
Langley, R.E.1
Burdett, S.2
Tierney, J.F.3
Cafferty, F.4
Parmar, M.K.5
Venning, G.6
-
29
-
-
79960992876
-
Beyond standard adjuvant therapy for colon cancer: Role of nonstandard interventions
-
Meyerhardt, J. A. Beyond standard adjuvant therapy for colon cancer: role of nonstandard interventions. Semin. Oncol. 2011, 38 (4), 533-541.
-
(2011)
Semin. Oncol
, vol.38
, Issue.4
, pp. 533-541
-
-
Meyerhardt, J.A.1
-
30
-
-
79953033708
-
Perspective: The big C - for Chemoprevention
-
Sporn, M. B. Perspective: The big C - for Chemoprevention. Nature 2011, 471(7339), S10-S11.
-
(2011)
Nature
, vol.471
, Issue.7339
-
-
Sporn, M.B.1
-
31
-
-
42249115328
-
Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma
-
Miselis, N. R.; Wu, Z. J.; Van Rooijen, N.; Kane, A. B. Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Mol. Cancer Ther. 2008, 7 (4), 788-799.
-
(2008)
Mol. Cancer Ther
, vol.7
, Issue.4
, pp. 788-799
-
-
Miselis, N.R.1
Wu, Z.J.2
van Rooijen, N.3
Kane, A.B.4
-
32
-
-
77955982989
-
Zoledronic acid impairs myeloid differentiation to tumour-associated macro-phages in mesothelioma
-
Veltman, J. D.; Lambers, M. E.; van Nimwegen, M.; Hendriks, R. W.; Hoogsteden, H. C.; Hegmans, J. P.; Aerts, J. G. Zoledronic acid impairs myeloid differentiation to tumour-associated macro-phages in mesothelioma. Br. J. Cancer 2010, 103 (5), 629-641.
-
(2010)
Br. J. Cancer
, vol.103
, Issue.5
, pp. 629-641
-
-
Veltman, J.D.1
Lambers, M.E.2
van Nimwegen, M.3
Hendriks, R.W.4
Hoogsteden, H.C.5
Hegmans, J.P.6
Aerts, J.G.7
-
33
-
-
0031469819
-
Antiangio-genic therapy of experimental cancer does not induce acquired drug resistance
-
Boehm, T.; Folkman, J.; Browder, T.; O'Reilly, M. S. Antiangio-genic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997, 390 (6658), 404-407.
-
(1997)
Nature
, vol.390
, Issue.6658
, pp. 404-407
-
-
Boehm, T.1
Folkman, J.2
Browder, T.3
O'Reilly, M.S.4
-
34
-
-
84855516339
-
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a phase 3, randomised, placebo-controlled trial
-
Smith, M. R.; Saad, F.; Coleman, R.; Shore, N.; Fizazi, K.; Tombal, B.; Miller, K.; Sieber, P.; Karsh, L.; Damiao, R.; Tammela, T. L.; Egerdie, B.; Van Poppel, H.; Chin, J.; Morote, J.; Gomez-Veiga, F.; Borkowski, T.; Ye, Z.; Kupic, A.; Dansey, R.; Goessl, C. Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial. Lancet 2012, 379 (9810), 39-46.
-
(2012)
Lancet
, vol.379
, Issue.9810
, pp. 39-46
-
-
Smith, M.R.1
Saad, F.2
Coleman, R.3
Shore, N.4
Fizazi, K.5
Tombal, B.6
Miller, K.7
Sieber, P.8
Karsh, L.9
Damiao, R.10
Tammela, T.L.11
Egerdie, B.12
van Poppel, H.13
Chin, J.14
Morote, J.15
Gomez-Veiga, F.16
Borkowski, T.17
Ye, Z.18
Kupic, A.19
Dansey, R.20
Goessl, C.21
more..
-
35
-
-
79952360832
-
Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, double-blind study
-
Fizazi, K.; Carducci, M.; Smith, M.; Damiao, R.; Brown, J.; Karsh, L.; Milecki, P.; Shore, N.; Rader, M.; Wang, H.; Jiang, Q.; Tadros, S.; Dansey, R.; Goessl, C. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet 2011, 377 (9768), 813-822.
-
(2011)
Lancet
, vol.377
, Issue.9768
, pp. 813-822
-
-
Fizazi, K.1
Carducci, M.2
Smith, M.3
Damiao, R.4
Brown, J.5
Karsh, L.6
Milecki, P.7
Shore, N.8
Rader, M.9
Wang, H.10
Jiang, Q.11
Tadros, S.12
Dansey, R.13
Goessl, C.14
-
36
-
-
80052499480
-
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
-
Lyons, T. R.; O'Brien, J.; Borges, V. F.; Conklin, M. W.; Keely, P. J.; Eliceiri, K. W.; Marusyk, A.; Tan, A. C.; Schedin, P. Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat. Med. 2011, 17 (9), 1109-1115.
-
(2011)
Nat. Med
, vol.17
, Issue.9
, pp. 1109-1115
-
-
Lyons, T.R.1
O'Brien, J.2
Borges, V.F.3
Conklin, M.W.4
Keely, P.J.5
Eliceiri, K.W.6
Marusyk, A.7
Tan, A.C.8
Schedin, P.9
-
37
-
-
56749107194
-
The tumor microenvironment and its contribution to tumor evolution toward metastasis
-
Lorusso, G.; Ruegg, C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem. Cell Biol. 2008, 130 (6), 1091-1103.
-
(2008)
Histochem. Cell Biol
, vol.130
, Issue.6
, pp. 1091-1103
-
-
Lorusso, G.1
Ruegg, C.2
-
38
-
-
0038352053
-
Radical causes of cancer
-
Hussain, S. P.; Hofseth, L. J.; Harris, C. C. Radical causes of cancer. Nat. Rev. Cancer 2003, 3 (4), 276-285.
-
(2003)
Nat. Rev. Cancer
, vol.3
, Issue.4
, pp. 276-285
-
-
Hussain, S.P.1
Hofseth, L.J.2
Harris, C.C.3
-
39
-
-
0032112771
-
Nitric oxide and oxygen radicals in infection, inflammation, and cancer
-
Maeda, H.; Akaike, T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry (Mosc) 1998, 63 (7), 854-865.
-
(1998)
Biochemistry (Mosc)
, vol.63
, Issue.7
, pp. 854-865
-
-
Maeda, H.1
Akaike, T.2
-
40
-
-
84862499885
-
Non-steroidal anti-inflammatory drugs and cancer incidence by sex in the VITamins And Lifestyle (VITAL) cohort
-
Brasky, T. M.; Potter, J. D.; Kristal, A. R.; Patterson, R. E.; Peters, U.; Asgari, M. M.; Thornquist, M. D.; White, E. Non-steroidal anti-inflammatory drugs and cancer incidence by sex in the VITamins And Lifestyle (VITAL) cohort. Cancer Causes Control 2012, 23 (3), 431-444.
-
(2012)
Cancer Causes Control
, vol.23
, Issue.3
, pp. 431-444
-
-
Brasky, T.M.1
Potter, J.D.2
Kristal, A.R.3
Patterson, R.E.4
Peters, U.5
Asgari, M.M.6
Thornquist, M.D.7
White, E.8
-
41
-
-
84857047419
-
Aspirin, Nonaspirin Nonsteroidal Anti-inflammatory Drugs, or Acetaminophen and Risk of Ovarian Cancer
-
Lo-Ciganic, W. H.; Zgibor, J. C.; Bunker, C. H.; Moysich, K. B.; Edwards, R. P.; Ness, R. B. Aspirin, Nonaspirin Nonsteroidal Anti-inflammatory Drugs, or Acetaminophen and Risk of Ovarian Cancer. Epidemiology 2012.
-
(2012)
Epidemiology
-
-
Lo-Ciganic, W.H.1
Zgibor, J.C.2
Bunker, C.H.3
Moysich, K.B.4
Edwards, R.P.5
Ness, R.B.6
-
42
-
-
0036136731
-
Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents
-
Tosetti, F.; Ferrari, N.; De Flora, S.; Albini, A. Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J. 2002, 16 (1), 2-14.
-
(2002)
FASEB J
, vol.16
, Issue.1
, pp. 2-14
-
-
Tosetti, F.1
Ferrari, N.2
de Flora, S.3
Albini, A.4
-
43
-
-
33745239300
-
Effect of silibinin on the growth and progression of primary lung tumors in mice
-
Singh, R. P.; Deep, G.; Chittezhath, M.; Kaur, M.; Dwyer-Nield, L. D.; Malkinson, A. M.; Agarwal, R. Effect of silibinin on the growth and progression of primary lung tumors in mice. J. Natl. Cancer Inst. 2006, 98 (12), 846-855.
-
(2006)
J. Natl. Cancer Inst
, vol.98
, Issue.12
, pp. 846-855
-
-
Singh, R.P.1
Deep, G.2
Chittezhath, M.3
Kaur, M.4
Dwyer-Nield, L.D.5
Malkinson, A.M.6
Agarwal, R.7
-
44
-
-
53049106036
-
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model
-
Raina, K.; Rajamanickam, S.; Singh, R. P.; Deep, G.; Chittezhath, M.; Agarwal, R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2008, 68 (16), 6822-6830.
-
(2008)
Cancer Res
, vol.68
, Issue.16
, pp. 6822-6830
-
-
Raina, K.1
Rajamanickam, S.2
Singh, R.P.3
Deep, G.4
Chittezhath, M.5
Agarwal, R.6
-
45
-
-
79961083687
-
Asiatic Acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models
-
Kavitha, C. V.; Agarwal, C.; Agarwal, R.; Deep, G. Asiatic Acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. PLoS One 2011, 6 (8), e22745.
-
(2011)
PLoS One
, vol.6
, Issue.8
-
-
Kavitha, C.V.1
Agarwal, C.2
Agarwal, R.3
Deep, G.4
-
46
-
-
78650691587
-
Anti-angiogenic effects of dietary isothiocyanates: Mechanisms of action and implications for human health
-
Cavell, B. E.; Syed Alwi, S. S.; Donlevy, A.; Packham, G. Anti-angiogenic effects of dietary isothiocyanates: mechanisms of action and implications for human health. Biochem. Pharmacol. 2011, 81(3), 327-336.
-
(2011)
Biochem. Pharmacol
, vol.81
, Issue.3
, pp. 327-336
-
-
Cavell, B.E.1
Syed Alwi, S.S.2
Donlevy, A.3
Packham, G.4
-
47
-
-
0142186748
-
Antiangiogenic activity of chemopreventive drugs
-
Pfeffer, U.; Ferrari, N.; Morini, M.; Benelli, R.; Noonan, D. M.; Albini, A. Antiangiogenic activity of chemopreventive drugs. Int. J. Biol. Markers 2003, 18 (1), 70-74.
-
(2003)
Int. J. Biol. Markers
, vol.18
, Issue.1
, pp. 70-74
-
-
Pfeffer, U.1
Ferrari, N.2
Morini, M.3
Benelli, R.4
Noonan, D.M.5
Albini, A.6
-
48
-
-
75249094454
-
Calorie restriction and cancer prevention: Metabolic and molecular mechanisms
-
Longo, V. D.; Fontana, L. Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol. Sci. 2010, 31(2), 89-98.
-
(2010)
Trends Pharmacol. Sci
, vol.31
, Issue.2
, pp. 89-98
-
-
Longo, V.D.1
Fontana, L.2
-
49
-
-
33847764645
-
Aging, adiposity, and calorie restriction
-
Fontana, L.; Klein, S. Aging, adiposity, and calorie restriction. JAMA 2007, 297(9), 986-994.
-
(2007)
JAMA
, vol.297
, Issue.9
, pp. 986-994
-
-
Fontana, L.1
Klein, S.2
-
50
-
-
0013072999
-
Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans
-
Hursting, S. D.; Lavigne, J. A.; Berrigan, D.; Perkins, S. N.; Barrett, J. C. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu. Rev. Med. 2003, 54,131-152.
-
(2003)
Annu. Rev. Med
, vol.54
, pp. 131-152
-
-
Hursting, S.D.1
Lavigne, J.A.2
Berrigan, D.3
Perkins, S.N.4
Barrett, J.C.5
-
51
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain, R. K. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat. Med. 2001, 7 (9), 987-989.
-
(2001)
Nat. Med
, vol.7
, Issue.9
, pp. 987-989
-
-
Jain, R.K.1
-
52
-
-
34447258681
-
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
-
Fukumura, D.; Jain, R. K. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J.Cell Biochem. 2007, 101 (4), 937-949.
-
(2007)
J.Cell Biochem
, vol.101
, Issue.4
, pp. 937-949
-
-
Fukumura, D.1
Jain, R.K.2
-
53
-
-
79960096827
-
Normalization of the vasculature for treatment of cancer and other diseases
-
Goel, S.; Duda, D. G.; Xu, L.; Munn, L. L.; Boucher, Y.; Fukumura, D.; Jain, R. K. Normalization of the vasculature for treatment of cancer and other diseases. Physiol. Rev. 2011, 91 (3), 1071-1121.
-
(2011)
Physiol. Rev
, vol.91
, Issue.3
, pp. 1071-1121
-
-
Goel, S.1
Duda, D.G.2
Xu, L.3
Munn, L.L.4
Boucher, Y.5
Fukumura, D.6
Jain, R.K.7
-
54
-
-
84862907876
-
Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion
-
Sorensen, A. G.; Emblem, K. E.; Polaskova, P.; Jennings, D.; Kim, H.; Ancukiewicz, M.; Wang, M.; Wen, P. Y.; Ivy, P.; Batchelor, T. T.; Jain, R. K. Increased Survival of Glioblastoma Patients Who Respond to Antiangiogenic Therapy with Elevated Blood Perfusion. Cancer Res. 2012, 72 (2), 402-407.
-
(2012)
Cancer Res
, vol.72
, Issue.2
, pp. 402-407
-
-
Sorensen, A.G.1
Emblem, K.E.2
Polaskova, P.3
Jennings, D.4
Kim, H.5
Ancukiewicz, M.6
Wang, M.7
Wen, P.Y.8
Ivy, P.9
Batchelor, T.T.10
Jain, R.K.11
-
55
-
-
78650051896
-
Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway
-
Coscia, M.; Quaglino, E.; Iezzi, M.; Curcio, C.; Pantaleoni, F.; Riganti, C.; Holen, I.; Monkkonen, H.; Boccadoro, M.; Forni, G.; Musiani, P.; Bosia, A.; Cavallo, F.; Massaia, M. Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. J. Cell Mol. Med. 2010, 14 (12), 2803-2815.
-
(2010)
J. Cell Mol. Med
, vol.14
, Issue.12
, pp. 2803-2815
-
-
Coscia, M.1
Quaglino, E.2
Iezzi, M.3
Curcio, C.4
Pantaleoni, F.5
Riganti, C.6
Holen, I.7
Monkkonen, H.8
Boccadoro, M.9
Forni, G.10
Musiani, P.11
Bosia, A.12
Cavallo, F.13
Massaia, M.14
-
56
-
-
33845941617
-
Anticancer potential of silymarin: From bench to bed side
-
Agarwal, R.; Agarwal, C.; Ichikawa, H.; Singh, R. P.; Aggarwal, B. B. Anticancer potential of silymarin: from bench to bed side. Anticancer Res. 2006, 26 (6B), 4457-4498.
-
(2006)
Anticancer Res
, vol.26
, Issue.6 B
, pp. 4457-4498
-
-
Agarwal, R.1
Agarwal, C.2
Ichikawa, H.3
Singh, R.P.4
Aggarwal, B.B.5
-
57
-
-
33846519345
-
Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine
-
Pradhan, S. C.; Girish, C. Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian J. Med. Res. 2006, 124 (5), 491-504.
-
(2006)
Indian J. Med. Res
, vol.124
, Issue.5
, pp. 491-504
-
-
Pradhan, S.C.1
Girish, C.2
-
58
-
-
77957598340
-
Antimetastatic efficacy of silibinin: Molecular mechanisms and therapeutic potential against cancer
-
Deep, G.; Agarwal, R. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer Metastasis Rev. 2010, 29 (3), 447-463.
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.3
, pp. 447-463
-
-
Deep, G.1
Agarwal, R.2
-
59
-
-
5144224381
-
A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer
-
Singh, R. P.; Agarwal, R. A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer. Mutat. Res. 2004, 555 (1-2), 21-32.
-
(2004)
Mutat. Res
, vol.555
, Issue.1-2
, pp. 21-32
-
-
Singh, R.P.1
Agarwal, R.2
-
60
-
-
27644439523
-
Mechanisms and preclinical efficacy of silibinin in preventing skin cancer
-
Singh, R. P.; Agarwal, R. Mechanisms and preclinical efficacy of silibinin in preventing skin cancer. Eur. J. Cancer 2005, 41 (13), 1969-1979.
-
(2005)
Eur. J. Cancer
, vol.41
, Issue.13
, pp. 1969-1979
-
-
Singh, R.P.1
Agarwal, R.2
-
61
-
-
33745002041
-
Prostate cancer chemoprevention by silibinin: Bench to bedside
-
Singh, R. P.; Agarwal, R. Prostate cancer chemoprevention by silibinin: bench to bedside. Mol. Carcinog. 2006, 45 (6), 436-442.
-
(2006)
Mol. Carcinog
, vol.45
, Issue.6
, pp. 436-442
-
-
Singh, R.P.1
Agarwal, R.2
-
62
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan, D.; Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86 (3), 353-364.
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
63
-
-
33748940402
-
Role of angiogenesis in human tumor dormancy: Animal models of the angiogenic switch
-
Naumov, G. N.; Akslen, L. A.; Folkman, J. Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch. Cell Cycle 2006, 5 (16), 1779-1787.
-
(2006)
Cell Cycle
, vol.5
, Issue.16
, pp. 1779-1787
-
-
Naumov, G.N.1
Akslen, L.A.2
Folkman, J.3
-
64
-
-
57449097365
-
Angiogenesis in pre-malignant conditions
-
Menakuru, S. R.; Brown, N. J.; Staton, C. A.; Reed, M. W. Angiogenesis in pre-malignant conditions. Br. J. Cancer 2008, 99 (12), 1961-1966.
-
(2008)
Br. J. Cancer
, vol.99
, Issue.12
, pp. 1961-1966
-
-
Menakuru, S.R.1
Brown, N.J.2
Staton, C.A.3
Reed, M.W.4
-
65
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers, G.; Benjamin, L. E. Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 2003, 3(6), 401-410.
-
(2003)
Nat. Rev. Cancer
, vol.3
, Issue.6
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
66
-
-
57349142011
-
Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: Comparison with silymarin and silibinin
-
Deep, G.; Raina, K.; Singh, R. P.; Oberlies, N. H.; Kroll, D. J.; Agarwal, R. Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin. Int. J. Cancer 2008, 123 (12), 2750-2758.
-
(2008)
Int. J. Cancer
, vol.123
, Issue.12
, pp. 2750-2758
-
-
Deep, G.1
Raina, K.2
Singh, R.P.3
Oberlies, N.H.4
Kroll, D.J.5
Agarwal, R.6
-
67
-
-
14644410403
-
Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: Implications for angioprevention and antiangiogenic therapy
-
Singh, R. P.; Dhanalakshmi, S.; Agarwal, C.; Agarwal, R. Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy. Oncogene 2005, 24 (7), 1188-1202.
-
(2005)
Oncogene
, vol.24
, Issue.7
, pp. 1188-1202
-
-
Singh, R.P.1
Dhanalakshmi, S.2
Agarwal, C.3
Agarwal, R.4
-
68
-
-
62349117597
-
Growth inhibition and regression of lung tumors by silibinin: Modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3
-
Tyagi, A.; Singh, R. P.; Ramasamy, K.; Raina, K.; Redente, E. F.; Dwyer-Nield, L. D.; Radcliffe, R. A.; Malkinson, A. M.; Agarwal, R. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3. Cancer Prev. Res. (Phila Pa) 2009, 2 (1), 74-83.
-
(2009)
Cancer Prev. Res. (Phila Pa)
, vol.2
, Issue.1
, pp. 74-83
-
-
Tyagi, A.1
Singh, R.P.2
Ramasamy, K.3
Raina, K.4
Redente, E.F.5
Dwyer-Nield, L.D.6
Radcliffe, R.A.7
Malkinson, A.M.8
Agarwal, R.9
-
69
-
-
77950255061
-
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin
-
Rajamanickam, S.; Velmurugan, B.; Kaur, M.; Singh, R. P.; Agarwal, R. Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin. Cancer Res. 2010, 70 (6), 2368-2378.
-
(2010)
Cancer Res
, vol.70
, Issue.6
, pp. 2368-2378
-
-
Rajamanickam, S.1
Velmurugan, B.2
Kaur, M.3
Singh, R.P.4
Agarwal, R.5
-
70
-
-
59449097284
-
Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling
-
Singh, R. P.; Raina, K.; Deep, G.; Chan, D.; Agarwal, R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling. Clin. Cancer Res. 2009, 15 (2), 613-621.
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.2
, pp. 613-621
-
-
Singh, R.P.1
Raina, K.2
Deep, G.3
Chan, D.4
Agarwal, R.5
-
71
-
-
40949106128
-
Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis
-
Singh, R. P.; Gu, M.; Agarwal, R. Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. Cancer Res. 2008, 68 (6), 2043-2050.
-
(2008)
Cancer Res
, vol.68
, Issue.6
, pp. 2043-2050
-
-
Singh, R.P.1
Gu, M.2
Agarwal, R.3
-
72
-
-
61549128686
-
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats
-
Velmurugan, B.; Singh, R. P.; Tyagi, A.; Agarwal, R. Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats. Cancer Prev. Res. (Phila. Pa.) 2008, 1 (5), 376-384.
-
(2008)
Cancer Prev. Res. (Phila. Pa.)
, vol.1
, Issue.5
, pp. 376-384
-
-
Velmurugan, B.1
Singh, R.P.2
Tyagi, A.3
Agarwal, R.4
-
73
-
-
59449085306
-
Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice
-
Singh, R. P.; Raina, K.; Sharma, G.; Agarwal, R. Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice. Clin. Cancer Res. 2008, 14 (23), 7773-7780.
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.23
, pp. 7773-7780
-
-
Singh, R.P.1
Raina, K.2
Sharma, G.3
Agarwal, R.4
-
74
-
-
0036606413
-
Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels
-
Singh, R. P.; Dhanalakshmi, S.; Tyagi, A. K.; Chan, D. C.; Agarwal, C.; Agarwal, R. Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Res. 2002, 62 (11), 3063-3069.
-
(2002)
Cancer Res
, vol.62
, Issue.11
, pp. 3063-3069
-
-
Singh, R.P.1
Dhanalakshmi, S.2
Tyagi, A.K.3
Chan, D.C.4
Agarwal, C.5
Agarwal, R.6
-
75
-
-
77957355392
-
Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules
-
Velmurugan, B.; Gangar, S. C.; Kaur, M.; Tyagi, A.; Deep, G.; Agarwal, R. Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules. Pharm. Res. 2010, 27 (10), 2085-2097.
-
(2010)
Pharm. Res
, vol.27
, Issue.10
, pp. 2085-2097
-
-
Velmurugan, B.1
Gangar, S.C.2
Kaur, M.3
Tyagi, A.4
Deep, G.5
Agarwal, R.6
-
76
-
-
77956674637
-
Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice
-
Ravichandran, K.; Velmurugan, B.; Gu, M.; Singh, R. P.; Agarwal, R. Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice. Clin. Cancer Res. 2010, 16(18), 4595-4606.
-
(2010)
Clin. Cancer Res
, vol.16
, Issue.18
, pp. 4595-4606
-
-
Ravichandran, K.1
Velmurugan, B.2
Gu, M.3
Singh, R.P.4
Agarwal, R.5
-
77
-
-
23944519382
-
Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation
-
Yang, S. H.; Lin, J. K.; Huang, C. J.; Chen, W. S.; Li, S. Y.; Chiu, J. H. Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation. J. Surg. Res. 2005, 128 (1), 140-146.
-
(2005)
J. Surg. Res
, vol.128
, Issue.1
, pp. 140-146
-
-
Yang, S.H.1
Lin, J.K.2
Huang, C.J.3
Chen, W.S.4
Li, S.Y.5
Chiu, J.H.6
-
78
-
-
79951823058
-
Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: Potential of real-time micro-CT in lung cancer chemoprevention studies
-
Ramasamy, K.; Dwyer-Nield, L. D.; Serkova, N. J.; Hasebroock, K. M.; Tyagi, A.; Raina, K.; Singh, R. P.; Malkinson, A. M.; Agarwal, R. Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies. Clin. Cancer Res. 2011, 17 (4), 753-761.
-
(2011)
Clin. Cancer Res
, vol.17
, Issue.4
, pp. 753-761
-
-
Ramasamy, K.1
Dwyer-Nield, L.D.2
Serkova, N.J.3
Hasebroock, K.M.4
Tyagi, A.5
Raina, K.6
Singh, R.P.7
Malkinson, A.M.8
Agarwal, R.9
-
79
-
-
51049109239
-
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells
-
Chittezhath, M.; Deep, G.; Singh, R. P.; Agarwal, C.; Agarwal, R. Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. Mol. Cancer Ther. 2008, 7 (7), 1817-1826.
-
(2008)
Mol. Cancer Ther
, vol.7
, Issue.7
, pp. 1817-1826
-
-
Chittezhath, M.1
Deep, G.2
Singh, R.P.3
Agarwal, C.4
Agarwal, R.5
-
80
-
-
34248192416
-
Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice
-
Gu, M.; Singh, R. P.; Dhanalakshmi, S.; Agarwal, C.; Agarwal, R. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Res. 2007, 67 (7), 3483-3491.
-
(2007)
Cancer Res
, vol.67
, Issue.7
, pp. 3483-3491
-
-
Gu, M.1
Singh, R.P.2
Dhanalakshmi, S.3
Agarwal, C.4
Agarwal, R.5
-
81
-
-
37549009050
-
Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin
-
Singh, R. P.; Tyagi, A.; Sharma, G.; Mohan, S.; Agarwal, R. Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin. Clin. Cancer Res. 2008, 14(1), 300-308.
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.1
, pp. 300-308
-
-
Singh, R.P.1
Tyagi, A.2
Sharma, G.3
Mohan, S.4
Agarwal, R.5
-
82
-
-
0042736063
-
Anti-angiogenic effect of silymarin on colon cancer LoVo cell line
-
Yang, S. H.; Lin, J. K.; Chen, W. S.; Chiu, J. H. Anti-angiogenic effect of silymarin on colon cancer LoVo cell line. J. Surg. Res. 2003, 113 (1), 133-138.
-
(2003)
J. Surg. Res
, vol.113
, Issue.1
, pp. 133-138
-
-
Yang, S.H.1
Lin, J.K.2
Chen, W.S.3
Chiu, J.H.4
-
83
-
-
1542438807
-
Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells
-
Yoo, H. G.; Jung, S. N.; Hwang, Y. S.; Park, J. S.; Kim, M. H.; Jeong, M.; Ahn, S. J.; Ahn, B. W.; Shin, B. A.; Park, R. K.; Jung, Y. D. Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells. Int. J. Mol. Med. 2004, 13 (1), 81-86.
-
(2004)
Int. J. Mol. Med
, vol.13
, Issue.1
, pp. 81-86
-
-
Yoo, H.G.1
Jung, S.N.2
Hwang, Y.S.3
Park, J.S.4
Kim, M.H.5
Jeong, M.6
Ahn, S.J.7
Ahn, B.W.8
Shin, B.A.9
Park, R.K.10
Jung, Y.D.11
-
84
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur, J.; Dayan, F.; Mazure, N. M. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 2006, 441 (7092), 437-443.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
85
-
-
59549107896
-
Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: Implications for anticancer therapy
-
Garcia-Maceira, P.; Mateo, J. Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy. Oncogene 2009, 28 (3), 313-324.
-
(2009)
Oncogene
, vol.28
, Issue.3
, pp. 313-324
-
-
Garcia-Maceira, P.1
Mateo, J.2
-
86
-
-
70349928634
-
Silibinin inhibits expression of HIF-1alpha through suppression of protein translation in prostate cancer cells
-
Jung, H. J.; Park, J. W.; Lee, J. S.; Lee, S. R.; Jang, B. C.; Suh, S. I.; Suh, M. H.; Baek, W. K. Silibinin inhibits expression of HIF-1alpha through suppression of protein translation in prostate cancer cells. Biochem. Biophys. Res. Commun. 2009, 390 (1), 71-76.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.390
, Issue.1
, pp. 71-76
-
-
Jung, H.J.1
Park, J.W.2
Lee, J.S.3
Lee, S.R.4
Jang, B.C.5
Suh, S.I.6
Suh, M.H.7
Baek, W.K.8
-
87
-
-
67349099566
-
Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells
-
Kim, S.; Choi, J. H.; Lim, H. I.; Lee, S. K.; Kim, W. W.; Kim, J. S.; Kim, J. H.; Choe, J. H.; Yang, J. H.; Nam, S. J.; Lee, J. E. Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells. Phytomedicine 2009, 16 (6-7), 573-580.
-
(2009)
Phytomedicine
, vol.16
, Issue.6-7
, pp. 573-580
-
-
Kim, S.1
Choi, J.H.2
Lim, H.I.3
Lee, S.K.4
Kim, W.W.5
Kim, J.S.6
Kim, J.H.7
Choe, J.H.8
Yang, J.H.9
Nam, S.J.10
Lee, J.E.11
-
88
-
-
33745684527
-
Metastasis: A question of life or death
-
Mehlen, P.; Puisieux, A. Metastasis: a question of life or death. Nat. Rev. Cancer 2006, 6 (6), 449-458.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.6
, pp. 449-458
-
-
Mehlen, P.1
Puisieux, A.2
-
89
-
-
33746407123
-
Identifying site-specific metastasis genes and functions
-
Gupta, G. P.; Minn, A. J.; Kang, Y.; Siegel, P. M.; Serganova, I.; Cordon-Cardo, C.; Olshen, A. B.; Gerald, W. L.; Massague, J. Identifying site-specific metastasis genes and functions. Cold Spring Harb. Symp. Quant. Biol. 2005, 70, 149-158.
-
(2005)
Cold Spring Harb. Symp. Quant. Biol
, vol.70
, pp. 149-158
-
-
Gupta, G.P.1
Minn, A.J.2
Kang, Y.3
Siegel, P.M.4
Serganova, I.5
Cordon-Cardo, C.6
Olshen, A.B.7
Gerald, W.L.8
Massague, J.9
-
90
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
Nguyen, D. X.; Massague, J. Genetic determinants of cancer metastasis. Nat. Rev. Genet. 2007, 8 (5), 341-352.
-
(2007)
Nat. Rev. Genet
, vol.8
, Issue.5
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
91
-
-
57349101056
-
Osteotropic cancers: From primary tumor to bone
-
Buijs, J. T.; van der Pluijm, G. Osteotropic cancers: from primary tumor to bone. Cancer Lett. 2009, 273 (2), 177-193.
-
(2009)
Cancer Lett
, vol.273
, Issue.2
, pp. 177-193
-
-
Buijs, J.T.1
van der Pluijm, G.2
-
92
-
-
0038481970
-
The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
-
Fidler, I. J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 2003, 3 (6), 453-458.
-
(2003)
Nat. Rev. Cancer
, vol.3
, Issue.6
, pp. 453-458
-
-
Fidler, I.J.1
-
93
-
-
0033137070
-
Extracellular matrix and integrin signalling: The shape of things to come
-
Boudreau, N. J.; Jones, P. L. Extracellular matrix and integrin signalling: the shape of things to come. Biochem. J. 1999, 339 (Pt 3), 481-488.
-
(1999)
Biochem. J
, vol.339
, Issue.PART 3
, pp. 481-488
-
-
Boudreau, N.J.1
Jones, P.L.2
-
94
-
-
79953220086
-
Ligand-independent activation of c-Met by fibronectin and alpha(5)beta(1)-integrin regulates ovarian cancer invasion and metastasis
-
Mitra, A. K.; Sawada, K.; Tiwari, P.; Mui, K.; Gwin, K.; Lengyel, E. Ligand-independent activation of c-Met by fibronectin and alpha(5)beta(1)-integrin regulates ovarian cancer invasion and metastasis. Oncogene 2011, 30 (13), 1566-1576.
-
(2011)
Oncogene
, vol.30
, Issue.13
, pp. 1566-1576
-
-
Mitra, A.K.1
Sawada, K.2
Tiwari, P.3
Mui, K.4
Gwin, K.5
Lengyel, E.6
-
95
-
-
77349088920
-
Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation
-
Lee, M.; Park, J. J.; Lee, Y. S. Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation. Oncol. Rep. 2010, 23 (3), 757-761.
-
(2010)
Oncol. Rep
, vol.23
, Issue.3
, pp. 757-761
-
-
Lee, M.1
Park, J.J.2
Lee, Y.S.3
-
96
-
-
34249110580
-
Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression
-
Yang, Z.; Zhang, X.; Gang, H.; Li, X.; Li, Z.; Wang, T.; Han, J.; Luo, T.; Wen, F.; Wu, X. Up-regulation of gastric cancer cell invasion by Twist is accompanied by N-cadherin and fibronectin expression. Biochem. Biophys. Res. Commun. 2007, 358 (3), 925-930.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.358
, Issue.3
, pp. 925-930
-
-
Yang, Z.1
Zhang, X.2
Gang, H.3
Li, X.4
Li, Z.5
Wang, T.6
Han, J.7
Luo, T.8
Wen, F.9
Wu, X.10
-
97
-
-
47549097718
-
Evaluation of silibinin on the viability, migration and adhesion of the human prostate adenocarcinoma (PC-3) cell line
-
Mokhtari, M. J.; Motamed, N.; Shokrgozar, M. A. Evaluation of silibinin on the viability, migration and adhesion of the human prostate adenocarcinoma (PC-3) cell line. Cell Biol. Int. 2008, 32 (8), 888-892.
-
(2008)
Cell Biol. Int
, vol.32
, Issue.8
, pp. 888-892
-
-
Mokhtari, M.J.1
Motamed, N.2
Shokrgozar, M.A.3
-
98
-
-
77953383219
-
Silibinin suppresses CD44 expression in prostate cancer cells
-
Handorean, A. M.; Yang, K.; Robbins, E. W.; Flaig, T. W.; Iczkowski, K. A. Silibinin suppresses CD44 expression in prostate cancer cells. Am. J. Transl. Res. 2009, 1 (1), 80-86.
-
(2009)
Am. J. Transl. Res
, vol.1
, Issue.1
, pp. 80-86
-
-
Handorean, A.M.1
Yang, K.2
Robbins, E.W.3
Flaig, T.W.4
Iczkowski, K.A.5
-
99
-
-
34447094968
-
Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2
-
Hsieh, Y. S.; Chu, S. C.; Yang, S. F.; Chen, P. N.; Liu, Y. C.; Lu, K. H. Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2. Carcinogenesis 2007, 28 (5), 977-987.
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 977-987
-
-
Hsieh, Y.S.1
Chu, S.C.2
Yang, S.F.3
Chen, P.N.4
Liu, Y.C.5
Lu, K.H.6
-
100
-
-
26044455880
-
Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways
-
Chen, P. N.; Hsieh, Y. S.; Chiou, H. L.; Chu, S. C. Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. Chem. Biol. Interact. 2005, 156 (2-3), 141-150.
-
(2005)
Chem. Biol. Interact
, vol.156
, Issue.2-3
, pp. 141-150
-
-
Chen, P.N.1
Hsieh, Y.S.2
Chiou, H.L.3
Chu, S.C.4
-
101
-
-
68349113541
-
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression
-
Wu, K. J.; Zeng, J.; Zhu, G. D.; Zhang, L. L.; Zhang, D.; Li, L.; Fan, J. H.; Wang, X. Y.; He, D. L. Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression. Acta. Pharmacol. Sin. 2009, 30 (8), 1162-1168.
-
(2009)
Acta. Pharmacol. Sin
, vol.30
, Issue.8
, pp. 1162-1168
-
-
Wu, K.J.1
Zeng, J.2
Zhu, G.D.3
Zhang, L.L.4
Zhang, D.5
Li, L.6
Fan, J.H.7
Wang, X.Y.8
He, D.L.9
-
102
-
-
33846326821
-
Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells
-
Lee, S. O.; Jeong, Y. J.; Im, H. G.; Kim, C. H.; Chang, Y. C.; Lee, I. S. Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells. Biochem. Biophys. Res. Commun. 2007, 354 (1), 165-171.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.354
, Issue.1
, pp. 165-171
-
-
Lee, S.O.1
Jeong, Y.J.2
Im, H.G.3
Kim, C.H.4
Chang, Y.C.5
Lee, I.S.6
-
103
-
-
3142765979
-
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
-
Chu, S. C.; Chiou, H. L.; Chen, P. N.; Yang, S. F.; Hsieh, Y. S. Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Mol. Carcinog. 2004, 40 (3), 143-149.
-
(2004)
Mol. Carcinog
, vol.40
, Issue.3
, pp. 143-149
-
-
Chu, S.C.1
Chiou, H.L.2
Chen, P.N.3
Yang, S.F.4
Hsieh, Y.S.5
-
104
-
-
33744824356
-
Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway
-
Chen, P. N.; Hsieh, Y. S.; Chiang, C. L.; Chiou, H. L.; Yang, S. F.; Chu, S. C. Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway. J. Dent. Res. 2006, 85 (3), 220-225.
-
(2006)
J. Dent. Res
, vol.85
, Issue.3
, pp. 220-225
-
-
Chen, P.N.1
Hsieh, Y.S.2
Chiang, C.L.3
Chiou, H.L.4
Yang, S.F.5
Chu, S.C.6
-
105
-
-
76649085810
-
Silibinin inhibits invasive properties of human glioblastoma U87MG cells through suppression of cathepsin B and nuclear factor kappa B-mediated induction of matrix metalloproteinase 9
-
Momeny, M.; Malehmir, M.; Zakidizaji, M.; Ghasemi, R.; Ghadimi, H.; Shokrgozar, M. A.; Emami, A. H.; Nafissi, S.; Ghavamzadeh, A.; Ghaffari, S. H. Silibinin inhibits invasive properties of human glioblastoma U87MG cells through suppression of cathepsin B and nuclear factor kappa B-mediated induction of matrix metalloproteinase 9. Anticancer Drugs, 21 (3), 252-260.
-
Anticancer Drugs
, vol.21
, Issue.3
, pp. 252-260
-
-
Momeny, M.1
Malehmir, M.2
Zakidizaji, M.3
Ghasemi, R.4
Ghadimi, H.5
Shokrgozar, M.A.6
Emami, A.H.7
Nafissi, S.8
Ghavamzadeh, A.9
Ghaffari, S.H.10
-
106
-
-
33749024777
-
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
-
Christiansen, J. J.; Rajasekaran, A. K. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res. 2006, 66 (17), 8319-8326.
-
(2006)
Cancer Res
, vol.66
, Issue.17
, pp. 8319-8326
-
-
Christiansen, J.J.1
Rajasekaran, A.K.2
-
107
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak, K.; Weinberg, R. A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 2009, 9(4), 265-273.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.4
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
108
-
-
80051505318
-
Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells
-
Deep, G.; Gangar, S. C.; Agarwal, C.; Agarwal, R. Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells. Cancer Prev. Res. (Phila. Pa.) 2011, 4 (8), 1222-1232.
-
(2011)
Cancer Prev. Res. (Phila. Pa.)
, vol.4
, Issue.8
, pp. 1222-1232
-
-
Deep, G.1
Gangar, S.C.2
Agarwal, C.3
Agarwal, R.4
-
109
-
-
15944425998
-
Dynamic process of prostate cancer metastasis to bone
-
Tantivejkul, K.; Kalikin, L. M.; Pienta, K. J. Dynamic process of prostate cancer metastasis to bone. J. Cell Biochem. 2004, 91 (4), 706-717.
-
(2004)
J. Cell Biochem
, vol.91
, Issue.4
, pp. 706-717
-
-
Tantivejkul, K.1
Kalikin, L.M.2
Pienta, K.J.3
-
110
-
-
42949179038
-
Mechanisms of bone metastasis in prostate cancer: Clinical implications
-
Msaouel, P.; Pissimissis, N.; Halapas, A.; Koutsilieris, M. Mechanisms of bone metastasis in prostate cancer: clinical implications. Best Pract. Res. Clin. Endocrinol. Metab. 2008, 22 (2), 341-355.
-
(2008)
Best Pract. Res. Clin. Endocrinol. Metab
, vol.22
, Issue.2
, pp. 341-355
-
-
Msaouel, P.1
Pissimissis, N.2
Halapas, A.3
Koutsilieris, M.4
-
111
-
-
69249244442
-
Molecular mechanisms of metastasis in prostate cancer
-
Clarke, N. W.; Hart, C. A.; Brown, M. D. Molecular mechanisms of metastasis in prostate cancer. Asian J. Androl. 2009, 11 (1), 57-67.
-
(2009)
Asian J. Androl
, vol.11
, Issue.1
, pp. 57-67
-
-
Clarke, N.W.1
Hart, C.A.2
Brown, M.D.3
-
112
-
-
84055177046
-
Osteoblastogenesis and osteoprotection enhanced by flavonolignan silibinin in osteoblasts and osteoclasts
-
Kim, J. L.; Kang, S. W.; Kang, M. K.; Gong, J. H.; Lee, E. S.; Han, S. J.; Kang, Y. H. Osteoblastogenesis and osteoprotection enhanced by flavonolignan silibinin in osteoblasts and osteoclasts. J. Cell Biochem. 2012, 113 (1), 247-259.
-
(2012)
J. Cell Biochem
, vol.113
, Issue.1
, pp. 247-259
-
-
Kim, J.L.1
Kang, S.W.2
Kang, M.K.3
Gong, J.H.4
Lee, E.S.5
Han, S.J.6
Kang, Y.H.7
-
113
-
-
70349607938
-
Silibinin inhibits osteoclast differentiation mediated by TNF family members
-
Kim, J. H.; Kim, K.; Jin, H. M.; Song, I.; Youn, B. U.; Lee, J.; Kim, N. Silibinin inhibits osteoclast differentiation mediated by TNF family members. Mol. Cells 2009, 28 (3), 201-207.
-
(2009)
Mol. Cells
, vol.28
, Issue.3
, pp. 201-207
-
-
Kim, J.H.1
Kim, K.2
Jin, H.M.3
Song, I.4
Youn, B.U.5
Lee, J.6
Kim, N.7
-
114
-
-
33846031926
-
The molecular understanding of osteoclast differentiation
-
Asagiri, M.; Takayanagi, H. The molecular understanding of osteoclast differentiation. Bone 2007, 40 (2), 251-264.
-
(2007)
Bone
, vol.40
, Issue.2
, pp. 251-264
-
-
Asagiri, M.1
Takayanagi, H.2
-
115
-
-
77649191328
-
NFATc1: Functions in osteoclasts
-
Zhao, Q.; Wang, X.; Liu, Y.; He, A.; Jia, R. NFATc1: functions in osteoclasts. Int. J. Biochem. Cell Biol. 2010, 42 (5), 576-579.
-
(2010)
Int. J. Biochem. Cell Biol
, vol.42
, Issue.5
, pp. 576-579
-
-
Zhao, Q.1
Wang, X.2
Liu, Y.3
He, A.4
Jia, R.5
-
116
-
-
33947194048
-
Effect of the silybin-phosphatidylcholine complex (IdB 1016) on the development of mammary tumors in HER-2/neu transgenic mice
-
Provinciali, M.; Papalini, F.; Orlando, F.; Pierpaoli, S.; Donnini, A.; Morazzoni, P.; Riva, A.; Smorlesi, A. Effect of the silybin-phosphatidylcholine complex (IdB 1016) on the development of mammary tumors in HER-2/neu transgenic mice. Cancer Res. 2007, 67 (5), 2022-2029.
-
(2007)
Cancer Res
, vol.67
, Issue.5
, pp. 2022-2029
-
-
Provinciali, M.1
Papalini, F.2
Orlando, F.3
Pierpaoli, S.4
Donnini, A.5
Morazzoni, P.6
Riva, A.7
Smorlesi, A.8
-
117
-
-
0029929692
-
Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells
-
Dehmlow, C.; Murawski, N.; de Groot, H. Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. Life Sci. 1996, 58 (18), 1591-1600.
-
(1996)
Life Sci
, vol.58
, Issue.18
, pp. 1591-1600
-
-
Dehmlow, C.1
Murawski, N.2
de Groot, H.3
-
118
-
-
33748299573
-
Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in mice
-
Meeran, S. M.; Katiyar, S.; Elmets, C. A.; Katiyar, S. K. Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in mice. Mol. Cancer Ther. 2006, 5 (7), 1660-1668.
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.7
, pp. 1660-1668
-
-
Meeran, S.M.1
Katiyar, S.2
Elmets, C.A.3
Katiyar, S.K.4
-
119
-
-
80054928143
-
The correlation between NF-kappaB inhibition and disease activity by coadministration of silibinin and ursodeoxycholic acid in experimental colitis
-
Esmaily, H.; Vaziri-Bami, A.; Miroliaee, A. E.; Baeeri, M.; Abdollahi, M. The correlation between NF-kappaB inhibition and disease activity by coadministration of silibinin and ursodeoxycholic acid in experimental colitis. Fundam. Clin. Pharmacol. 2011, 25 (6), 723-733.
-
(2011)
Fundam. Clin. Pharmacol
, vol.25
, Issue.6
, pp. 723-733
-
-
Esmaily, H.1
Vaziri-Bami, A.2
Miroliaee, A.E.3
Baeeri, M.4
Abdollahi, M.5
-
120
-
-
0141963117
-
Inhibitors of cyclo-oxygenase 2: A new class of anticancer agents?
-
Gasparini, G.; Longo, R.; Sarmiento, R.; Morabito, A. Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents? Lancet. Oncol. 2003, 4 (10), 605-615.
-
(2003)
Lancet. Oncol
, vol.4
, Issue.10
, pp. 605-615
-
-
Gasparini, G.1
Longo, R.2
Sarmiento, R.3
Morabito, A.4
-
121
-
-
80355141481
-
Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: Involvement of STAT and MAPK pathways
-
Ravichandran, K.; Tyagi, A.; Deep, G.; Agarwal, C.; Agarwal, R. Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways. Indian J. Exp. Biol. 2011, 49 (11), 840-847.
-
(2011)
Indian J. Exp. Biol
, vol.49
, Issue.11
, pp. 840-847
-
-
Ravichandran, K.1
Tyagi, A.2
Deep, G.3
Agarwal, C.4
Agarwal, R.5
-
122
-
-
20544478077
-
Inflammation and cancer: Is the link as simple as we think?
-
x-xiv
-
Nickoloff, B. J.; Ben-Neriah, Y.; Pikarsky, E. Inflammation and cancer: is the link as simple as we think? J. Invest. Dermatol. 2005, 124 (6), x-xiv.
-
(2005)
J. Invest. Dermatol
, vol.124
, Issue.6
-
-
Nickoloff, B.J.1
Ben-Neriah, Y.2
Pikarsky, E.3
-
123
-
-
84888126768
-
Silibinin modulates TNF-alpha and IFN-gamma mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells
-
Tyagi, A.; Agarwal, C.; Dwyer-Nield, L. D.; Singh, R. P.; Malkinson, A. M.; Agarwal, R. Silibinin modulates TNF-alpha and IFN-gamma mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Mol.
-
Mol
-
-
Tyagi, A.1
Agarwal, C.2
Dwyer-Nield, L.D.3
Singh, R.P.4
Malkinson, A.M.5
Agarwal, R.6
-
124
-
-
84873256085
-
Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF-kappaB signaling
-
Raina, K.; Agarwal, C.; Agarwal, R. Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF-kappaB signaling. Mol. Carcinog. 2013, 53 (3), 195-206.
-
(2013)
Mol. Carcinog
, vol.53
, Issue.3
, pp. 195-206
-
-
Raina, K.1
Agarwal, C.2
Agarwal, R.3
-
125
-
-
0037034863
-
Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis
-
Dhanalakshmi, S.; Singh, R. P.; Agarwal, C.; Agarwal, R. Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis. Oncogene 2002, 21 (11), 1759-1767.
-
(2002)
Oncogene
, vol.21
, Issue.11
, pp. 1759-1767
-
-
Dhanalakshmi, S.1
Singh, R.P.2
Agarwal, C.3
Agarwal, R.4
-
126
-
-
65949108395
-
Silibinin feeding alters the metabolic profile in TRAMP prostatic tumors: 1H-NMRS-based metabolomics study
-
Raina, K.; Serkova, N. J.; Agarwal, R. Silibinin feeding alters the metabolic profile in TRAMP prostatic tumors: 1H-NMRS-based metabolomics study. Cancer Res. 2009, 69 (9), 3731-3735.
-
(2009)
Cancer Res
, vol.69
, Issue.9
, pp. 3731-3735
-
-
Raina, K.1
Serkova, N.J.2
Agarwal, R.3
-
127
-
-
0034667455
-
Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells
-
Zi, X.; Zhang, J.; Agarwal, R.; Pollak, M. Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells. Cancer Res. 2000, 60 (20), 5617-5620.
-
(2000)
Cancer Res
, vol.60
, Issue.20
, pp. 5617-5620
-
-
Zi, X.1
Zhang, J.2
Agarwal, R.3
Pollak, M.4
-
128
-
-
77952317006
-
A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer
-
Flaig, T. W.; Glode, M.; Gustafson, D.; van Bokhoven, A.; Tao, Y.; Wilson, S.; Su, L. J.; Li, Y.; Harrison, G.; Agarwal, R.; Crawford, E. D.; Lucia, M. S.; Pollak, M. A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer. Prostate 2010, 70 (8), 848-855.
-
(2010)
Prostate
, vol.70
, Issue.8
, pp. 848-855
-
-
Flaig, T.W.1
Glode, M.2
Gustafson, D.3
van Bokhoven, A.4
Tao, Y.5
Wilson, S.6
Su, L.J.7
Li, Y.8
Harrison, G.9
Agarwal, R.10
Crawford, E.D.11
Lucia, M.S.12
Pollak, M.13
-
129
-
-
33845899681
-
A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients
-
Flaig, T. W.; Gustafson, D. L.; Su, L. J.; Zirrolli, J. A.; Crighton, F.; Harrison, G. S.; Pierson, A. S.; Agarwal, R.; Glode, L. M. A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. Invest. New Drugs 2007, 25 (2), 139-146.
-
(2007)
Invest. New Drugs
, vol.25
, Issue.2
, pp. 139-146
-
-
Flaig, T.W.1
Gustafson, D.L.2
Su, L.J.3
Zirrolli, J.A.4
Crighton, F.5
Harrison, G.S.6
Pierson, A.S.7
Agarwal, R.8
Glode, L.M.9
-
130
-
-
33646739493
-
Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: Silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences
-
Hoh, C.; Boocock, D.; Marczylo, T.; Singh, R.; Berry, D. P.; Dennison, A. R.; Hemingway, D.; Miller, A.; West, K.; Euden, S.; Garcea, G.; Farmer, P. B.; Steward, W. P.; Gescher, A. J. Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences. Clin. Cancer Res. 2006, 12 (9), 2944-2950.
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.9
, pp. 2944-2950
-
-
Hoh, C.1
Boocock, D.2
Marczylo, T.3
Singh, R.4
Berry, D.P.5
Dennison, A.R.6
Hemingway, D.7
Miller, A.8
West, K.9
Euden, S.10
Garcea, G.11
Farmer, P.B.12
Steward, W.P.13
Gescher, A.J.14
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