Upregulation of GLT-1 by treatment with ceftriaxone alleviates radicular pain by reducing spinal astrocyte activation and neuronal hyperexcitability

Journal of Neuroscience Research

Volumn 92, Issue 1, 2014, Pages 116-129

  Nicholson, K J ^a   Gilliland, T M ^a   Winkelstein, B A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ceftriaxone; Glutamate transporter; Neuronal hyperexcitability; Pain; Radiculopathy

Indexed keywords

CEFTRIAXONE; EXCITATORY AMINO ACID TRANSPORTER; GLIAL FIBRILLARY ACIDIC PROTEIN; SODIUM CHLORIDE; VESICULAR GLUTAMATE TRANSPORTER 1;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; HYPERALGESIA; MALE; MECHANICAL STIMULATION; NERVE ROOT COMPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADICULAR PAIN; RAT; SPINAL CORD DORSAL HORN; THERMAL STIMULATION; UPREGULATION;

CEFTRIAXONE; GLUTAMATE TRANSPORTER; NEURONAL HYPEREXCITABILITY; PAIN; RADICULOPATHY;

ANIMALS; ASTROCYTES; CEFTRIAXONE; EXCITATORY AMINO ACID TRANSPORTER 2; MALE; NEURONS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RADICULOPATHY; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; UP-REGULATION;

EID: 84888058186     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23295     Document Type: Article

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