메뉴 건너뛰기




Volumn 41, Issue 3, 2008, Pages 677-685

Transient cervical nerve root compression modulates pain: Load thresholds for allodynia and sustained changes in spinal neuropeptide expression

Author keywords

Cervical; Load; Neck pain; Nerve root; Threshold

Indexed keywords

IMMUNOLOGY; LIVING SYSTEMS STUDIES; LOADING; NEURONS; PEPTIDES;

EID: 38749141392     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2007.09.026     Document Type: Article
Times cited : (40)

References (62)
  • 1
    • 0029655582 scopus 로고    scopus 로고
    • Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain
    • Abbadie C., Brown J.L., Mantyh P.W., and Basbaum A.I. Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience 70 (1996) 201-209
    • (1996) Neuroscience , vol.70 , pp. 201-209
    • Abbadie, C.1    Brown, J.L.2    Mantyh, P.W.3    Basbaum, A.I.4
  • 2
    • 0032978019 scopus 로고    scopus 로고
    • Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury
    • Allen B.J., Li J., Menning P.M., Rogers S.D., Ghilardi J., Mantyh P.W., and Simone D.A. Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. Journal of Neurophysiology 81 (1999) 1379-1390
    • (1999) Journal of Neurophysiology , vol.81 , pp. 1379-1390
    • Allen, B.J.1    Li, J.2    Menning, P.M.3    Rogers, S.D.4    Ghilardi, J.5    Mantyh, P.W.6    Simone, D.A.7
  • 3
    • 22144434056 scopus 로고    scopus 로고
    • Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents
    • Aoki Y., Ohtori S., Takahashi K., Ino H., Douya H., Ozawa T., Saito T., and Moriya H. Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents. Spine 30 (2005) 1496-1500
    • (2005) Spine , vol.30 , pp. 1496-1500
    • Aoki, Y.1    Ohtori, S.2    Takahashi, K.3    Ino, H.4    Douya, H.5    Ozawa, T.6    Saito, T.7    Moriya, H.8
  • 4
    • 0038243652 scopus 로고    scopus 로고
    • Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions
    • Araujo M.C., Sinnott C.J., and Strichartz G.R. Multiple phases of relief from experimental mechanical allodynia by systemic lidocaine: responses to early and late infusions. Pain 103 (2003) 21-29
    • (2003) Pain , vol.103 , pp. 21-29
    • Araujo, M.C.1    Sinnott, C.J.2    Strichartz, G.R.3
  • 5
    • 0000315153 scopus 로고
    • Estimating transition between 2 intersecting straight lines
    • Bacon D.W., and Watts D.G. Estimating transition between 2 intersecting straight lines. Biometrika 58 (1971) 525-534
    • (1971) Biometrika , vol.58 , pp. 525-534
    • Bacon, D.W.1    Watts, D.G.2
  • 6
    • 0034193925 scopus 로고    scopus 로고
    • Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chronic central pain
    • Bennett A.D., Chastain K.M., and Hulsebosch C.E. Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chronic central pain. Pain 86 (2000) 163-175
    • (2000) Pain , vol.86 , pp. 163-175
    • Bennett, A.D.1    Chastain, K.M.2    Hulsebosch, C.E.3
  • 7
    • 0036160387 scopus 로고    scopus 로고
    • Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist
    • Cahill C.M., and Coderre T.J. Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist. Pain 95 (2002) 277-285
    • (2002) Pain , vol.95 , pp. 277-285
    • Cahill, C.M.1    Coderre, T.J.2
  • 8
    • 33751513742 scopus 로고    scopus 로고
    • Unconfined compression of white matter
    • Cheng S., and Bilston L.E. Unconfined compression of white matter. Journal of Biomechanics 40 (2007) 117-124
    • (2007) Journal of Biomechanics , vol.40 , pp. 117-124
    • Cheng, S.1    Bilston, L.E.2
  • 9
    • 0031259346 scopus 로고    scopus 로고
    • Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat
    • Christensen M.D., and Hulsebosch C.E. Spinal cord injury and anti-NGF treatment results in changes in CGRP density and distribution in the dorsal horn in the rat. Experimental Neurology 147 (1997) 463-475
    • (1997) Experimental Neurology , vol.147 , pp. 463-475
    • Christensen, M.D.1    Hulsebosch, C.E.2
  • 10
    • 33748306146 scopus 로고    scopus 로고
    • Material properties of porcine parietal cortex
    • Coats B., and Margulies S.S. Material properties of porcine parietal cortex. Journal of Biomechanics 39 (2006) 2521-2525
    • (2006) Journal of Biomechanics , vol.39 , pp. 2521-2525
    • Coats, B.1    Margulies, S.S.2
  • 11
    • 0030859754 scopus 로고    scopus 로고
    • Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat
    • Colburn R.W., DeLeo J.A., Rickman A.J., Yeager M.P., Kwon P., and Hickey W.F. Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat. Journal of Neuroimmunology 79 (1997) 163-175
    • (1997) Journal of Neuroimmunology , vol.79 , pp. 163-175
    • Colburn, R.W.1    DeLeo, J.A.2    Rickman, A.J.3    Yeager, M.P.4    Kwon, P.5    Hickey, W.F.6
  • 12
    • 0032978701 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior
    • Colburn R.W., Rickman A.J., and DeLeo J.A. The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior. Experimental Neurology 157 (1999) 289-304
    • (1999) Experimental Neurology , vol.157 , pp. 289-304
    • Colburn, R.W.1    Rickman, A.J.2    DeLeo, J.A.3
  • 13
    • 4243430099 scopus 로고    scopus 로고
    • The Saskatchewan health and back pain survey: the prevalence of neck pain and related disability in Saskatchewan adults
    • Côté P., Cassidy J.D., and Carroll L. The Saskatchewan health and back pain survey: the prevalence of neck pain and related disability in Saskatchewan adults. Spine 23 (1998) 1689-1698
    • (1998) Spine , vol.23 , pp. 1689-1698
    • Côté, P.1    Cassidy, J.D.2    Carroll, L.3
  • 14
    • 0342313802 scopus 로고    scopus 로고
    • The factors associated with neck pain and its related disability in the Saskatchewan population
    • Côté P., Cassidy J.D., and Carroll L. The factors associated with neck pain and its related disability in the Saskatchewan population. Spine 25 (2000) 1109-1117
    • (2000) Spine , vol.25 , pp. 1109-1117
    • Côté, P.1    Cassidy, J.D.2    Carroll, L.3
  • 15
    • 9244236002 scopus 로고    scopus 로고
    • The annual incidence and course of neck pain in the general population: a population-based cohort study
    • Côté P., Cassidy J.D., Carroll L.J., and Kristman V. The annual incidence and course of neck pain in the general population: a population-based cohort study. Pain 112 (2004) 267-273
    • (2004) Pain , vol.112 , pp. 267-273
    • Côté, P.1    Cassidy, J.D.2    Carroll, L.J.3    Kristman, V.4
  • 17
    • 0024392352 scopus 로고
    • Intrathecal administration of CGRP in the rat attenuates a facilitation of the tail flick reflex induced by either substance P or noxious cutaneous stimulation
    • Cridland R.A., and Henry J.L. Intrathecal administration of CGRP in the rat attenuates a facilitation of the tail flick reflex induced by either substance P or noxious cutaneous stimulation. Neuroscience Letters 102 (1989) 241-246
    • (1989) Neuroscience Letters , vol.102 , pp. 241-246
    • Cridland, R.A.1    Henry, J.L.2
  • 18
    • 28644449260 scopus 로고    scopus 로고
    • Categorising the severity of neck pain: establishment of cut-points for use in clinical and epidemiological research
    • Fejer R., Jordan A., and Hartvigsen J. Categorising the severity of neck pain: establishment of cut-points for use in clinical and epidemiological research. Pain 119 (2005) 176-182
    • (2005) Pain , vol.119 , pp. 176-182
    • Fejer, R.1    Jordan, A.2    Hartvigsen, J.3
  • 19
    • 3242688027 scopus 로고    scopus 로고
    • Are in vivo and in situ brain tissues mechanically similar?
    • Gefen A., and Margulies S.S. Are in vivo and in situ brain tissues mechanically similar?. Journal of Biomechanics 37 (2004) 1339-1352
    • (2004) Journal of Biomechanics , vol.37 , pp. 1339-1352
    • Gefen, A.1    Margulies, S.S.2
  • 21
    • 0034657820 scopus 로고    scopus 로고
    • Spinal glial activation and cytokine expression after lumbar root injury in the rat
    • Hashizume H., DeLeo J.A., Colburn R.W., and Weinstein J.N. Spinal glial activation and cytokine expression after lumbar root injury in the rat. Spine 25 (2000) 1206-1217
    • (2000) Spine , vol.25 , pp. 1206-1217
    • Hashizume, H.1    DeLeo, J.A.2    Colburn, R.W.3    Weinstein, J.N.4
  • 22
    • 24744470059 scopus 로고    scopus 로고
    • Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries
    • Hubbard R.D., and Winkelstein B.A. Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries. Spine 30 (2005) 1924-1932
    • (2005) Spine , vol.30 , pp. 1924-1932
    • Hubbard, R.D.1    Winkelstein, B.A.2
  • 23
    • 0035478262 scopus 로고    scopus 로고
    • Repeated injury to the lumbar nerve roots produces enhanced mechanical allodynia and persistent spinal neuroinflammation
    • Hunt J.L., Winkelstein B.A., Rutkowski M.D., Weinstein J.N., and DeLeo J.A. Repeated injury to the lumbar nerve roots produces enhanced mechanical allodynia and persistent spinal neuroinflammation. Spine 19 (2001) 2073-2079
    • (2001) Spine , vol.19 , pp. 2073-2079
    • Hunt, J.L.1    Winkelstein, B.A.2    Rutkowski, M.D.3    Weinstein, J.N.4    DeLeo, J.A.5
  • 24
    • 1842685406 scopus 로고    scopus 로고
    • Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat
    • Jang J., Nam T., Paik K., and Leem J. Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat. Neuroscience Letters 360 (2004) 129-132
    • (2004) Neuroscience Letters , vol.360 , pp. 129-132
    • Jang, J.1    Nam, T.2    Paik, K.3    Leem, J.4
  • 25
    • 0242475309 scopus 로고    scopus 로고
    • Central sensitization and LTP: do pain and memory share similar mechanisms?
    • Ji R.R., Kohno T., Moore K.A., and Woolf C.J. Central sensitization and LTP: do pain and memory share similar mechanisms?. Trends Neurosciences 26 (2003) 696-705
    • (2003) Trends Neurosciences , vol.26 , pp. 696-705
    • Ji, R.R.1    Kohno, T.2    Moore, K.A.3    Woolf, C.J.4
  • 26
    • 0024452920 scopus 로고
    • Antinociceptive effect of intrathecally administered antiserum against calcitonin gene-related peptide on thermal and mechanical noxious stimuli in experimental hyperalgesic rats
    • Kawamura M., Kuraishi Y., Minami M., and Satoh M. Antinociceptive effect of intrathecally administered antiserum against calcitonin gene-related peptide on thermal and mechanical noxious stimuli in experimental hyperalgesic rats. Brain Research 497 (1989) 199-203
    • (1989) Brain Research , vol.497 , pp. 199-203
    • Kawamura, M.1    Kuraishi, Y.2    Minami, M.3    Satoh, M.4
  • 27
    • 33846230485 scopus 로고    scopus 로고
    • Electrophysiologic changes in dorsal root ganglion neurons and behavioral changes in a lumbar radiculopathy model
    • Kirita T., Takebayashi T., Mizuno S., Takeuchi H., Kobayashi T., Fukao M., Yamashita T., and Tohse N. Electrophysiologic changes in dorsal root ganglion neurons and behavioral changes in a lumbar radiculopathy model. Spine 32 (2007) E65-E72
    • (2007) Spine , vol.32
    • Kirita, T.1    Takebayashi, T.2    Mizuno, S.3    Takeuchi, H.4    Kobayashi, T.5    Fukao, M.6    Yamashita, T.7    Tohse, N.8
  • 28
    • 0036316481 scopus 로고    scopus 로고
    • Effect of mechanical compression on the vascular permeability of the dorsal root ganglion
    • Kobayashi S., and Yoshizawa H. Effect of mechanical compression on the vascular permeability of the dorsal root ganglion. Journal of Orthopaedic Research 20 (2002) 730-739
    • (2002) Journal of Orthopaedic Research , vol.20 , pp. 730-739
    • Kobayashi, S.1    Yoshizawa, H.2
  • 29
    • 0027228391 scopus 로고
    • Vasogenic edema induced by compression injury to the spinal nerve root. Distribution of intravenously injected protein tracers and gadolinium-enhanced magnetic resonance imaging
    • Kobayashi S., Yoshizawa H., Hachiya Y., Ukai T., and Morita T. Vasogenic edema induced by compression injury to the spinal nerve root. Distribution of intravenously injected protein tracers and gadolinium-enhanced magnetic resonance imaging. Spine 18 (1993) 1410-1424
    • (1993) Spine , vol.18 , pp. 1410-1424
    • Kobayashi, S.1    Yoshizawa, H.2    Hachiya, Y.3    Ukai, T.4    Morita, T.5
  • 30
    • 0347029798 scopus 로고    scopus 로고
    • Pathology of lumbar nerve root compression-Part 2: morphological and immunohistochemical changes of dorsal root ganglion
    • Kobayashi S., Yoshizawa H., and Yamada S. Pathology of lumbar nerve root compression-Part 2: morphological and immunohistochemical changes of dorsal root ganglion. Journal of Orthopaedic Research 22 (2004) 180-188
    • (2004) Journal of Orthopaedic Research , vol.22 , pp. 180-188
    • Kobayashi, S.1    Yoshizawa, H.2    Yamada, S.3
  • 31
    • 13444255976 scopus 로고    scopus 로고
    • Effect of lumbar nerve root compression on primary sensory neurons and their central branches: changes in the nociceptive neuropeptides substance P and somatostatin
    • Kobayashi S., Kokubo Y., Uchida K., Yayama T., Takeno K., Negoro K., Nakajima H., Baba H., and Yoshizawa H. Effect of lumbar nerve root compression on primary sensory neurons and their central branches: changes in the nociceptive neuropeptides substance P and somatostatin. Spine 30 (2005) 276-282
    • (2005) Spine , vol.30 , pp. 276-282
    • Kobayashi, S.1    Kokubo, Y.2    Uchida, K.3    Yayama, T.4    Takeno, K.5    Negoro, K.6    Nakajima, H.7    Baba, H.8    Yoshizawa, H.9
  • 33
    • 0033929741 scopus 로고    scopus 로고
    • Peripheral nerve injuries in athletes: a case series of over 200 injuries
    • Krivickas L.S., and Wilbourn A.J. Peripheral nerve injuries in athletes: a case series of over 200 injuries. Seminars in Neurology 20 (2000) 225-232
    • (2000) Seminars in Neurology , vol.20 , pp. 225-232
    • Krivickas, L.S.1    Wilbourn, A.J.2
  • 34
    • 3242683425 scopus 로고    scopus 로고
    • A novel rodent neck pain model of facet-mediated behavioral hypersensitivity: implications for persistent pain and whiplash injury
    • Lee K.E., Thinnes J.H., Gokhin D.S., and Winkelstein B.A. A novel rodent neck pain model of facet-mediated behavioral hypersensitivity: implications for persistent pain and whiplash injury. Journal of Neuroscience Methods 137 (2004) 151-159
    • (2004) Journal of Neuroscience Methods , vol.137 , pp. 151-159
    • Lee, K.E.1    Thinnes, J.H.2    Gokhin, D.S.3    Winkelstein, B.A.4
  • 36
    • 0033959466 scopus 로고    scopus 로고
    • Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord
    • Malcangio M., Ramer M.S., Boucher T.J., and McMahon S.B. Intrathecally injected neurotrophins and the release of substance P from the rat isolated spinal cord. European Journal of Neuroscience 12 (2000) 139-144
    • (2000) European Journal of Neuroscience , vol.12 , pp. 139-144
    • Malcangio, M.1    Ramer, M.S.2    Boucher, T.J.3    McMahon, S.B.4
  • 37
    • 0031775956 scopus 로고    scopus 로고
    • Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates
    • Malmberg A.B., and Basbaum A.I. Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates. Pain 76 (1998) 215-222
    • (1998) Pain , vol.76 , pp. 215-222
    • Malmberg, A.B.1    Basbaum, A.I.2
  • 38
    • 1642398355 scopus 로고    scopus 로고
    • Functional role of exogenous administration of substance P in chronic constriction injury model of neuropathic pain in gerbils
    • Meert T.F., Vissers K., Geenen F., and Kontinen V.K. Functional role of exogenous administration of substance P in chronic constriction injury model of neuropathic pain in gerbils. Pharmacology Biochemistry and Behavior 76 (2003) 17-25
    • (2003) Pharmacology Biochemistry and Behavior , vol.76 , pp. 17-25
    • Meert, T.F.1    Vissers, K.2    Geenen, F.3    Kontinen, V.K.4
  • 39
    • 0034333768 scopus 로고    scopus 로고
    • Mechanical properties of brain tissue in-vivo: experiment and computer simulation
    • Miller K., Chinzei K., Orssengo G., and Bednarz P. Mechanical properties of brain tissue in-vivo: experiment and computer simulation. Journal of Biomechanics 33 (2000) 1369-1376
    • (2000) Journal of Biomechanics , vol.33 , pp. 1369-1376
    • Miller, K.1    Chinzei, K.2    Orssengo, G.3    Bednarz, P.4
  • 40
    • 0141704311 scopus 로고    scopus 로고
    • Estimating regression models with unknown break-points
    • Muggeo V.M. Estimating regression models with unknown break-points. Statistics in Medicine 22 (2003) 3055-3071
    • (2003) Statistics in Medicine , vol.22 , pp. 3055-3071
    • Muggeo, V.M.1
  • 41
    • 0030447474 scopus 로고    scopus 로고
    • Neuropeptide changes persist in spinal cord despite resolving hyperalgesia in a rat model of mononeuropathy
    • Munglani R., Harrison S.M., Smith G.D., Bountra C., Birch P.J., Elliot P.J., and Hunt S.P. Neuropeptide changes persist in spinal cord despite resolving hyperalgesia in a rat model of mononeuropathy. Brain Research 743 (1996) 102-108
    • (1996) Brain Research , vol.743 , pp. 102-108
    • Munglani, R.1    Harrison, S.M.2    Smith, G.D.3    Bountra, C.4    Birch, P.J.5    Elliot, P.J.6    Hunt, S.P.7
  • 42
    • 0037086606 scopus 로고    scopus 로고
    • Neural space integrity of the lower cervical spine: effect of normal range of motion
    • Nuckley D.J., Konodi M.A., Raynak G.C., Ching R.P., and Mirza S.K. Neural space integrity of the lower cervical spine: effect of normal range of motion. Spine 27 (2002) 587-595
    • (2002) Spine , vol.27 , pp. 587-595
    • Nuckley, D.J.1    Konodi, M.A.2    Raynak, G.C.3    Ching, R.P.4    Mirza, S.K.5
  • 43
    • 0023143665 scopus 로고
    • Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
    • Oku R., Satoh M., Fujii N., Otaka A., Yajima H., and Takagi H. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain Research 403 (1987) 350-354
    • (1987) Brain Research , vol.403 , pp. 350-354
    • Oku, R.1    Satoh, M.2    Fujii, N.3    Otaka, A.4    Yajima, H.5    Takagi, H.6
  • 44
    • 0024391736 scopus 로고
    • Edema formation in spinal nerve roots induced by experimental, graded compression
    • Olmarker K., Rydevik B., and Holm S. Edema formation in spinal nerve roots induced by experimental, graded compression. Spine 6 (1989) 569-573
    • (1989) Spine , vol.6 , pp. 569-573
    • Olmarker, K.1    Rydevik, B.2    Holm, S.3
  • 46
    • 0034688281 scopus 로고    scopus 로고
    • Functional regeneration of sensory axons into the adult spinal cord
    • Ramer M.S., Priestley J.V., and McMahon S.B. Functional regeneration of sensory axons into the adult spinal cord. Nature 403 (2000) 312-316
    • (2000) Nature , vol.403 , pp. 312-316
    • Ramer, M.S.1    Priestley, J.V.2    McMahon, S.B.3
  • 48
    • 27944440508 scopus 로고    scopus 로고
    • Spinal neuropeptide responses in persistent and transient pain following cervical nerve root injury
    • Rothman S.M., Kreider R.A., and Winkelstein B.A. Spinal neuropeptide responses in persistent and transient pain following cervical nerve root injury. Spine 30 (2005) 2491-2496
    • (2005) Spine , vol.30 , pp. 2491-2496
    • Rothman, S.M.1    Kreider, R.A.2    Winkelstein, B.A.3
  • 49
    • 85159435881 scopus 로고    scopus 로고
    • Detection, transmission, and perception of pain
    • Slipman C.W., Derby R., Simeone F.A., and Mayer T.G. (Eds), Saunders, London
    • Rothman S.M., Hubbard R.D., Lee K.E., and Winkelstein B.A. Detection, transmission, and perception of pain. In: Slipman C.W., Derby R., Simeone F.A., and Mayer T.G. (Eds). Interventional Spine: An Algorithmic Approach (2007), Saunders, London
    • (2007) Interventional Spine: An Algorithmic Approach
    • Rothman, S.M.1    Hubbard, R.D.2    Lee, K.E.3    Winkelstein, B.A.4
  • 50
    • 0036668305 scopus 로고    scopus 로고
    • Lumbar nerve root injury induces central nervous system neuroimmune activation and neuroinflammation in the rat: relationship to painful radiculopathy
    • Rutkowski M.D., Winkelstein B.A., Hickey W.F., Pahl J.L., and DeLeo J.A. Lumbar nerve root injury induces central nervous system neuroimmune activation and neuroinflammation in the rat: relationship to painful radiculopathy. Spine 27 (2002) 1604-1613
    • (2002) Spine , vol.27 , pp. 1604-1613
    • Rutkowski, M.D.1    Winkelstein, B.A.2    Hickey, W.F.3    Pahl, J.L.4    DeLeo, J.A.5
  • 51
    • 0141643691 scopus 로고    scopus 로고
    • ISSLS Prize Winner: erythropoietin inhibits spinal neuronal apoptosis and pain following nerve root crush
    • Sekiguchi Y., Kikuchi S., Myers R.R., and Campana W.M. ISSLS Prize Winner: erythropoietin inhibits spinal neuronal apoptosis and pain following nerve root crush. Spine 28 (2003) 2577-2584
    • (2003) Spine , vol.28 , pp. 2577-2584
    • Sekiguchi, Y.1    Kikuchi, S.2    Myers, R.R.3    Campana, W.M.4
  • 52
    • 2442629188 scopus 로고    scopus 로고
    • Experimental spinal stenosis: relationship between degree of cauda equina compression, neuropathology, and pain
    • Sekiguchi M., Kikuchi S., and Myers R.R. Experimental spinal stenosis: relationship between degree of cauda equina compression, neuropathology, and pain. Spine 29 (2004) 1105-1111
    • (2004) Spine , vol.29 , pp. 1105-1111
    • Sekiguchi, M.1    Kikuchi, S.2    Myers, R.R.3
  • 54
    • 3042706233 scopus 로고    scopus 로고
    • Partial sciatic nerve transection causes redistribution of pain-related peptides and lowers withdrawal threshold
    • Swamydas M., Skoff A., and Adler J. Partial sciatic nerve transection causes redistribution of pain-related peptides and lowers withdrawal threshold. Experimental Neurology 188 (2004) 444-451
    • (2004) Experimental Neurology , vol.188 , pp. 444-451
    • Swamydas, M.1    Skoff, A.2    Adler, J.3
  • 55
    • 0032934824 scopus 로고    scopus 로고
    • Behavioral manifestations of neuropathic pain and mechanical allodynia, and changes in spinal dorsal horn neurons, following L4-L6 dorsal root constriction in rats
    • Tabo E., Jinks S.L., Eisele Jr. J.H., and Carstens E. Behavioral manifestations of neuropathic pain and mechanical allodynia, and changes in spinal dorsal horn neurons, following L4-L6 dorsal root constriction in rats. Pain 80 (1999) 503-520
    • (1999) Pain , vol.80 , pp. 503-520
    • Tabo, E.1    Jinks, S.L.2    Eisele Jr., J.H.3    Carstens, E.4
  • 57
    • 0037195594 scopus 로고    scopus 로고
    • Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: considerations for persistent pain
    • Winkelstein B.A., and DeLeo J.A. Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: considerations for persistent pain. Brain Research 956 (2002) 294-301
    • (2002) Brain Research , vol.956 , pp. 294-301
    • Winkelstein, B.A.1    DeLeo, J.A.2
  • 58
    • 2442603445 scopus 로고    scopus 로고
    • Mechanical thresholds for initiation and persistence of pain following nerve root injury: mechanical and chemical contributions and injury
    • Winkelstein B.A., and DeLeo J.A. Mechanical thresholds for initiation and persistence of pain following nerve root injury: mechanical and chemical contributions and injury. Journal of Biomechanical Engineering 126 (2004) 258-263
    • (2004) Journal of Biomechanical Engineering , vol.126 , pp. 258-263
    • Winkelstein, B.A.1    DeLeo, J.A.2
  • 59
    • 0035888084 scopus 로고    scopus 로고
    • Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment
    • Winkelstein B.A., Rutkowski M.D., Sweitzer S.M., Pahl J.L., and DeLeo J.A. Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment. Journal of Comparative Neurology 439 (2001) 127-139
    • (2001) Journal of Comparative Neurology , vol.439 , pp. 127-139
    • Winkelstein, B.A.1    Rutkowski, M.D.2    Sweitzer, S.M.3    Pahl, J.L.4    DeLeo, J.A.5
  • 60
    • 0035888956 scopus 로고    scopus 로고
    • Quantification of neural tissue injury in a rat radiculopathy model: comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons
    • Winkelstein B.A., Rutkowski M.D., Weinstein J.N., and DeLeo J.A. Quantification of neural tissue injury in a rat radiculopathy model: comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons. Journal of Neuroscience Methods 111 (2001) 49-57
    • (2001) Journal of Neuroscience Methods , vol.111 , pp. 49-57
    • Winkelstein, B.A.1    Rutkowski, M.D.2    Weinstein, J.N.3    DeLeo, J.A.4
  • 61
    • 0036123303 scopus 로고    scopus 로고
    • The role of mechanical deformation in lumbar radiculopathy
    • Winkelstein B.A., Weinstein J.N., and DeLeo J.A. The role of mechanical deformation in lumbar radiculopathy. Spine 27 (2002) 27-33
    • (2002) Spine , vol.27 , pp. 27-33
    • Winkelstein, B.A.1    Weinstein, J.N.2    DeLeo, J.A.3
  • 62
    • 0026026937 scopus 로고
    • Common patterns of plasticity contributing to nociceptive sensitization in mammals and Aplysia
    • Woolf C.J., and Walters E.T. Common patterns of plasticity contributing to nociceptive sensitization in mammals and Aplysia. Trends in Neuroscience 14 (1991) 74-78
    • (1991) Trends in Neuroscience , vol.14 , pp. 74-78
    • Woolf, C.J.1    Walters, E.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.