Changes in responses of wide dynamic range neurons in the spinal dorsal horn after dorsal root or dorsal root ganglion compression

Spine

Volumn 21, Issue 12, 1996, Pages 1408-1415

  Hanai, Fumihiko ^a   Matsui, Nobuo ^b   Hongo, Nobuo ^a  

^a Inabe General Hospital   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

disc herniation; nociception; radicular pain; spinal dorsal horn; wide dynamic range neuron

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CAT; CONFERENCE PAPER; DORSAL ROOT; ELECTROPHYSIOLOGY; INTERVERTEBRAL DISK HERNIA; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RADICULAR PAIN; RECEPTIVE FIELD; SPINAL CORD COMPRESSION; SPINAL CORD DORSAL HORN; SPINAL GANGLION;

ANIMALS; CATS; FEMALE; GANGLIA, SPINAL; MALE; NERVE COMPRESSION SYNDROMES; NEURONS; PERONEAL NERVE; SENSORY THRESHOLDS; SPINAL CORD; SPINAL NERVE ROOTS; TIBIAL NERVE;

EID: 0029929978     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199606150-00002     Document Type: Conference Paper

References (44)

1. Badalamente MA, Dee R, Ghillanir, Chien P, Daniels K. Mechanical stimulation of dorsal root ganglia induces increased production of Substance P. Spine 1987;12:552-5.
2. Bennett GJ, Abdelmoumene M, Hayashi H, Dubner R. Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase. J Comp Neurol 1980;194:809-27.
3. Brown AG. Organization in the spinal cord. Berlin-Heidelberg-New York: Springer Verlag, 1981.
4. Bushnell MC, Duncan GH, Dubner R, He LF. Activity of trigeminothalamic neurons in medullary dorsal horn of awake monkeys trained in a thermal discrimination tusk. J Neurophysiol 1984;52:170-87.
5. Cervero F, Iggo A, Ogawa H. Nociceptor driven dorsal horn neurons in the lumbar spinal cord of the cat. Pain 1976; 2:5-24.
6. Christensen BN, Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: The marginal zone of the dorsal horn. J Neurophysiol 1970;33:293-307.
7. Chung JM, Kenshalo DR Jr, Gerhart KD, Willis WD. Excitation of primate spinothalamic neurons by cutaneous C-fiber volleys. J Neurophysiol 1979;42:1354-69.
8. Coghill RC, Mayer DJ, Price DD. Wide dynamic range but not nociceptive-specific neurons encode multidimertional features of prolonged repetitive heat pain. J Neurophysiol 1993;69:703-16.
9. Devor M, Bernstein JJ. Abnormal impulse generation in neuromas:electrophysiology and ultrastracture. In: Ochoa J, Culp W, eds. Abnormal nerves and muscles and impulse generators. Oxford: Oxford University Press, 1982;363-80.
10. Devor M, Wall PD. Cross-excitation in dorsal root ganglia of nerve-injured and intact rats. J Neurophysiol 1990;64: 1733-46.
11. Devor M. The pathophysiology of damaged peripheral nerves. Textbook of Pain. Edinburgh: Churchill Livingstone, 1994;79-100.
12. Dubner R, Sharav Y, Gracely RH, Price DD. Idiopathic trigeminal neuralgia: Sensory features and pain mechanisms. Pain 1987;31:23-33.
13. Dubner R, Dan R, Kenshalo JR, Maixner W, Bushnell MC, Oriveras J. The correlation of monkey medullary dorsal horn neuronal activity and the perceived intensity of noxious heat stimuli. J Neurophysiol 1989;62:450-7.
14. Dubuisson D. Nerve root damage and arachnoiditis. Textbook of Pain. Edinburgh: Churchill Livingstone, 1994; 711-38.
15. Dyson C, Brindley GS. Strength duration curves for the prediction of cutaneous pain. Clin Sci 1966;30:237-41.
16. Ferrington DG, Sorkin LS, Willis WD. Responses of spinothalamic tract cells in the superficical dorsal horn of the primate lumbar spinal cord. J Physiol (Lond) 1987;338:681-703.
17. Guilbaud G, Benelli G, Besson JM. Responses of thoracic dorsal horn interneurons to cutaneous stimulation and to the administration of algogenic substances into the mesenteric artery in the spinal cat. Brain Res 1977;124:437-48.
18. Hillman P, Wall PD. Inhibitory and exitatory factors influencing the receptive fields of lamina V spinal cord cells. Exp Brain Res 1969;9:284-306.
19. Howe JF, Looser JD, Calvin WH. Mechanosensitivity of dorsal root ganalia and chronically injured axons: A physiological basis for the radicular pain of nerve root compression. Pain 1977;3:25-41.
20. Kelly M. Is pain due to pressure on nerves? Spinal tumors and the intervertebral disk. Neurology 1956;6:32-6.
21. Lindblom K, Rexed B. Spinal nerve injury in dorsolateral protrusions of lumbar discs. J Neurosurg 1948;5:415-25.
22. Maixner W, Dubner R, Bushnell MC, Kenshalo DR, Oliven J. Wide dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli. Brain Res 1986;374:385-8.
23. Menetrey D, Giesler GJ, Besson JM. An analysis of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat. Exp Brain Res 1977;27:15-33.
24. Mixter WJ, Barr JS. Rupture of intervertebral disk with involvement of the spinal canal. N Engl J Med 1934;211: 210-5.
25. Price DD, Dubner R, Hu JW. Trigemino thalamic neurons in nucleus caudalis responsive to tactile, thermal, and nociceptive stimulation of monkey's face. J Neurophysiol 1976;39: 936-53.
26. Price DD, Hayes RL, Ruda M, Dubner R. Spatial and temporal transformations of input to spinothalamic tract neurons and their relation to somatic sensation. J Neurophysiol 1978;41:933-47.
27. Price DD, Hayashi H, Dubner R, Ruda MA. Functional relationships between neurons of marginal and substantia gelatinosa layers of primate dorsal horn. J Neurophysiol 1979; 42:1590-608.
28. Rexed B. A cytoarchitectonic atlas of the spinal cord in the cat. J Comp Neurol 1954;100:297-379.
29. Rydevik B, Lundborg G, Bagge U. Effects of greater compression on interneural blood flow. J Hand Surg 1981;6:3-12.
30. Schanta TR, Evons JA. The relationship of epidural anesthesia to neuromembranes and arachnoid villi. Anesthesiology 1972;37:543-57.
31. Smyth MJ, Wright V. Sciatica and the intervertebral disc. J Bone Joint Surg [Am] 1958;40:1401-2,17.
32. Surmeier DJ, Honda CN, Willis WD. Responses of primate spinothalanic neurons to noxious thermal stimulation of glabrous and hairy skin. J Neurophysiol 1986;56:328-50.
33. Tsubaki T, Yokota T. Heat-evoked responses of dorsal horn nociceptive neurons. Jpn J Pain Res 1981;3:4-5.
34. Tsubaki T, Yokota T. Heat-evoked responses of dorsal horn nociceptive neurons in the monkey. Jpn J Physiol 1983; 33:249-67.
35. Vanderlinden RG. Subarticular entrapement of the dorsal root ganglion as a cause of sciatic pain. Spine 1984;9:19-22.
36. Wall PD, Sweet WH. Temporary abolition of pain in man. Science 1967;155:108-9.
37. Wall PD, Waxman S, Basbaum AI. Ongoing activity in peripheral nerve:injury discharge. Exp Neurol 1974;45:576-89.
38. Wall PD, Devor M. The effect of peripheral nerve injury on dorsal root potentials and on transmission of afferent signals into the spinal cord. Brain Res 1981;209:95-111.
39. Wall PD, Devor M. Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. Pain 1983;17:321-39.
40. Weinstein J. Mechanisms of spinal pain the dorsal root ganglion and its role as a mediator of low back pain. Spine 1986;11:999-1001.
41. Woolf CJ, Wall PD. Chronic peripheral nerve section diminishes the primary afferent A-fibre mediated inhibition of rat dorsal horn neurones. Brain Res 1982;242:77-85.
42. Woolf CJ. The dorsal horn: State-dependent sensory processing and the generation of pain. Textbook of Pain. Edinburgh: Churchill Livingstone, 1994;101-12.
43. Yokota T, Nishikawa Y. Action of picrotoxin upon trigeminal subnucleus caudalis neurons in the monkey. Brain Res 1979;171:369-73.
44. Yokota T. Basic Mechanisms of Clinical Pain. Japan: Nankodo, 1990.