-
1
-
-
0023340731
-
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
-
Rine J., Herskowitz I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 1987, 116:9-22.
-
(1987)
Genetics
, vol.116
, pp. 9-22
-
-
Rine, J.1
Herskowitz, I.2
-
2
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum H.A., Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001, 410:227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
3
-
-
36248975293
-
SIRT1 transgenic mice show phenotypes resembling calorie restriction
-
Bordone L., Cohen D., Robinson A., Motta M.C., van Veen E., Czopik A., Steele A.D., Crowe H., Marmor S., Luo J., Gu W., Guarente L. SIRT1 transgenic mice show phenotypes resembling calorie restriction. Aging Cell 2007, 6:759-767.
-
(2007)
Aging Cell
, vol.6
, pp. 759-767
-
-
Bordone, L.1
Cohen, D.2
Robinson, A.3
Motta, M.C.4
van Veen, E.5
Czopik, A.6
Steele, A.D.7
Crowe, H.8
Marmor, S.9
Luo, J.10
Gu, W.11
Guarente, L.12
-
4
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T., Deng C.X., Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009, 460:587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
5
-
-
78649482634
-
SIRT1: recent lessons from mouse models
-
Herranz D., Serrano M. SIRT1: recent lessons from mouse models. Nat. Rev. Cancer 2010, 10:819-823.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 819-823
-
-
Herranz, D.1
Serrano, M.2
-
6
-
-
77949887506
-
Mammalian sirtuins: biological insights and disease relevance
-
Haigis M.C., Sinclair D.A. Mammalian sirtuins: biological insights and disease relevance. Ann. Rev. Pathol. 2010, 5:253-295.
-
(2010)
Ann. Rev. Pathol.
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
7
-
-
84855544817
-
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
-
Jiang M., Wang J., Fu J., Du L., Jeong H., West T., Xiang L., Peng Q., Hou Z., Cai H., Seredenina T., Arbez N., Zhu S., Sommers K., Qian J., Zhang J., Mori S., Yang X.W., Tamashiro K.L., Aja S., Moran T.H., Luthi-Carter R., Martin B., Maudsley S., Mattson M.P., Cichewicz R.H., Ross C.A., Holtzman D.M., Krainc D., Duan W. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat. Med. 2011, 18:153-158.
-
(2011)
Nat. Med.
, vol.18
, pp. 153-158
-
-
Jiang, M.1
Wang, J.2
Fu, J.3
Du, L.4
Jeong, H.5
West, T.6
Xiang, L.7
Peng, Q.8
Hou, Z.9
Cai, H.10
Seredenina, T.11
Arbez, N.12
Zhu, S.13
Sommers, K.14
Qian, J.15
Zhang, J.16
Mori, S.17
Yang, X.W.18
Tamashiro, K.L.19
Aja, S.20
Moran, T.H.21
Luthi-Carter, R.22
Martin, B.23
Maudsley, S.24
Mattson, M.P.25
Cichewicz, R.H.26
Ross, C.A.27
Holtzman, D.M.28
Krainc, D.29
Duan, W.30
more..
-
8
-
-
4143050290
-
The interaction between FOXO and SIRT1: tipping the balance towards survival
-
Giannakou M.E., Partridge L. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol. 2004, 14:408-412.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 408-412
-
-
Giannakou, M.E.1
Partridge, L.2
-
9
-
-
0036629251
-
Cell cycle and death control: long live Forkheads
-
Burgering B.M., Kops G.J. Cell cycle and death control: long live Forkheads. Trends Biochem. Sci. 2002, 27:352-360.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 352-360
-
-
Burgering, B.M.1
Kops, G.J.2
-
10
-
-
41649102028
-
Ambient glucose levels qualify the potency of insulin myogenic actions by regulating SIRT1 and FoxO3a in C2C12 myocytes
-
Nedachi T., Kadotani A., Ariga M., Katagiri H., Kanzaki M. Ambient glucose levels qualify the potency of insulin myogenic actions by regulating SIRT1 and FoxO3a in C2C12 myocytes. Am. J. Physiol. Endocrinol. Metab. 2008, 294:E668-E678.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
-
-
Nedachi, T.1
Kadotani, A.2
Ariga, M.3
Katagiri, H.4
Kanzaki, M.5
-
11
-
-
0036202199
-
Energy metabolism, stress hormones and neural recovery from cerebral ischemia/hypoxia
-
Schurr A. Energy metabolism, stress hormones and neural recovery from cerebral ischemia/hypoxia. Neurochem. Int. 2002, 41:1-8.
-
(2002)
Neurochem. Int.
, vol.41
, pp. 1-8
-
-
Schurr, A.1
-
12
-
-
0034306357
-
Brain ischemia and reperfusion: molecular mechanisms of neuronal injury
-
White B.C., Sullivan J.M., DeGracia D.J., O'Neil B.J., Neumar R.W., Grossman L.I., Rafols J.A., Krause G.S. Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J. Neurol. Sci. 2000, 179:1-33.
-
(2000)
J. Neurol. Sci.
, vol.179
, pp. 1-33
-
-
White, B.C.1
Sullivan, J.M.2
DeGracia, D.J.3
O'Neil, B.J.4
Neumar, R.W.5
Grossman, L.I.6
Rafols, J.A.7
Krause, G.S.8
-
13
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki T., Sasaki Y., Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 2004, 305:1010-1013.
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
14
-
-
31844450471
-
SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox
-
Tang B.L. SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox. Neurobiol. Aging 2006, 27:501-505.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 501-505
-
-
Tang, B.L.1
-
15
-
-
0042477712
-
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
-
Gilley J., Coffer P.J., Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J. Cell Biol. 2003, 162:613-622.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 613-622
-
-
Gilley, J.1
Coffer, P.J.2
Ham, J.3
-
16
-
-
12944294341
-
Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
-
Barthélémy C., Henderson C.E., Pettmann B. Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK. BMC Neurosci. 2004, 5:48.
-
(2004)
BMC Neurosci.
, vol.5
, pp. 48
-
-
Barthélémy, C.1
Henderson, C.E.2
Pettmann, B.3
-
17
-
-
0019862903
-
Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism
-
Gunning P.W., Landreth G.E., Layer P., Ignatius M., Shooter E.M. Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism. J. Neurosci. 1981, 1:368-379.
-
(1981)
J. Neurosci.
, vol.1
, pp. 368-379
-
-
Gunning, P.W.1
Landreth, G.E.2
Layer, P.3
Ignatius, M.4
Shooter, E.M.5
-
18
-
-
0037093669
-
Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia
-
Tabakman R., Lazarovici P., Kohen R. Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. J. Neurosci. Res. 2002, 68:463-469.
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 463-469
-
-
Tabakman, R.1
Lazarovici, P.2
Kohen, R.3
-
19
-
-
48149102116
-
Protective effect of erythropoietin on beta-amyloid-induced PC12 cell death through antioxidant mechanisms
-
Li G., Ma R., Huang C., Tang Q., Fu Q., Liu H., Hu B., Xiang J. Protective effect of erythropoietin on beta-amyloid-induced PC12 cell death through antioxidant mechanisms. Neurosci. Lett. 2008, 442:143-147.
-
(2008)
Neurosci. Lett.
, vol.442
, pp. 143-147
-
-
Li, G.1
Ma, R.2
Huang, C.3
Tang, Q.4
Fu, Q.5
Liu, H.6
Hu, B.7
Xiang, J.8
-
20
-
-
29744447230
-
Neuroprotection by NGF in the PC12 in vitro OGD model: involvement of mitogen-activated protein kinases and gene expression
-
Tabakman R., Jiang H., Shahar I., Arien-Zakay H., Levine R.A., Lazarovici P. Neuroprotection by NGF in the PC12 in vitro OGD model: involvement of mitogen-activated protein kinases and gene expression. Ann. N.Y. Acad. Sci. 2005, 1053:84-96.
-
(2005)
Ann. N.Y. Acad. Sci.
, vol.1053
, pp. 84-96
-
-
Tabakman, R.1
Jiang, H.2
Shahar, I.3
Arien-Zakay, H.4
Levine, R.A.5
Lazarovici, P.6
-
21
-
-
0027413399
-
Brain oxidative energy and related metabolism, neuronal stress, and Alzheimer's disease: a speculative synthesis
-
Hoyer S. Brain oxidative energy and related metabolism, neuronal stress, and Alzheimer's disease: a speculative synthesis. J. Geriatr. Psychiatry Neurol. 1993, 6:3-13.
-
(1993)
J. Geriatr. Psychiatry Neurol.
, vol.6
, pp. 3-13
-
-
Hoyer, S.1
-
22
-
-
0031020993
-
Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation
-
Mark R.J., Pang Z., Geddes J.W., Uchida K., Mattson M.P. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 1997, 17:1046-1054.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1046-1054
-
-
Mark, R.J.1
Pang, Z.2
Geddes, J.W.3
Uchida, K.4
Mattson, M.P.5
-
23
-
-
0023636605
-
Lowered cerebral glucose utilization in amyotrophic lateral sclerosis
-
Dalakas M.C., Hatazawa J., Brooks R.A., Di Chiro G. Lowered cerebral glucose utilization in amyotrophic lateral sclerosis. Ann. Neurol. 1987, 22:580-586.
-
(1987)
Ann. Neurol.
, vol.22
, pp. 580-586
-
-
Dalakas, M.C.1
Hatazawa, J.2
Brooks, R.A.3
Di Chiro, G.4
-
24
-
-
0141688316
-
Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line
-
Liu Y., Song X.D., Liu W., Zhang T.Y., Zuo J. Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line. J. Cell Mol. Med. 2003, 7:49-53.
-
(2003)
J. Cell Mol. Med.
, vol.7
, pp. 49-53
-
-
Liu, Y.1
Song, X.D.2
Liu, W.3
Zhang, T.Y.4
Zuo, J.5
-
25
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen H.Y., Miller C., Bitterman K.J., Wall N.R., Hekking B., Kessler B., Howitz K.T., Gorospe M., de Cabo R., Sinclair D.A. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004, 305:390-392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
de Cabo, R.9
Sinclair, D.A.10
-
26
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
Kume S., Uzu T., Horiike K., Chin-Kanasaki M., Isshiki K., Araki S., Sugimoto T., Haneda M., Kashiwagi A., Koya D. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J. Clin. Invest. 2010, 120:1043-1055.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
Chin-Kanasaki, M.4
Isshiki, K.5
Araki, S.6
Sugimoto, T.7
Haneda, M.8
Kashiwagi, A.9
Koya, D.10
-
27
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto S., Fergusson M.M., Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004, 306:2105-2108.
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
28
-
-
45549102566
-
Regulation of SIRT1 protein levels by nutrient availability
-
Kanfi Y., Peshti V., Gozlan Y.M., Rathaus M., Gil R., Cohen H.Y. Regulation of SIRT1 protein levels by nutrient availability. FEBS Lett. 2008, 582:2417-2423.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2417-2423
-
-
Kanfi, Y.1
Peshti, V.2
Gozlan, Y.M.3
Rathaus, M.4
Gil, R.5
Cohen, H.Y.6
-
29
-
-
79960620082
-
The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy
-
Sundaresan N.R., Pillai V.B., Wolfgeher D., Samant S., Vasudevan P., Parekh V., Raghuraman H., Cunningham J.M., Gupta M., Gupta M.P. The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci. Signal. 2011, 4:ra46.
-
(2011)
Sci. Signal.
, vol.4
-
-
Sundaresan, N.R.1
Pillai, V.B.2
Wolfgeher, D.3
Samant, S.4
Vasudevan, P.5
Parekh, V.6
Raghuraman, H.7
Cunningham, J.M.8
Gupta, M.9
Gupta, M.P.10
-
30
-
-
34548471739
-
Cytoplasm-localized SIRT1 enhances apoptosis
-
Jin Q., Yan T., Ge X., Sun C., Shi X., Zhai Q. Cytoplasm-localized SIRT1 enhances apoptosis. J. Cell Physiol. 2007, 213:88-97.
-
(2007)
J. Cell Physiol.
, vol.213
, pp. 88-97
-
-
Jin, Q.1
Yan, T.2
Ge, X.3
Sun, C.4
Shi, X.5
Zhai, Q.6
-
31
-
-
33847077943
-
FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells
-
Obexer P., Geiger K., Ambros P.F., Meister B., Ausserlechner M.J. FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells. Cell Death Differ. 2007, 14:534-547.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 534-547
-
-
Obexer, P.1
Geiger, K.2
Ambros, P.F.3
Meister, B.4
Ausserlechner, M.J.5
-
32
-
-
65249166592
-
Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis
-
Obexer P., Hagenbuchner J., Unterkircher T., Sachsenmaier N., Seifarth C., Böck G., Porto V., Geiger K., Ausserlechner M. Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis. Mol. Biol. Cell 2009, 20:2041-2048.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2041-2048
-
-
Obexer, P.1
Hagenbuchner, J.2
Unterkircher, T.3
Sachsenmaier, N.4
Seifarth, C.5
Böck, G.6
Porto, V.7
Geiger, K.8
Ausserlechner, M.9
-
33
-
-
0034671848
-
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells
-
Zheng W.H., Kar S., Quirion R. Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells. J. Biol. Chem. 2000, 275:39152-39158.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39152-39158
-
-
Zheng, W.H.1
Kar, S.2
Quirion, R.3
-
34
-
-
33846870605
-
Inhibition of wild-type p66ShcA in mesangial cells prevents glycooxidant-dependent FOXO3a regulation and promotes the survival phenotype
-
Chintapalli J., Yang S., Opawumi D., Goyal S.R., Shamsuddin N., Malhotra A., Reiss K., Meggs L.G. Inhibition of wild-type p66ShcA in mesangial cells prevents glycooxidant-dependent FOXO3a regulation and promotes the survival phenotype. Am. J. Physiol. Renal Physiol. 2007, 292:F523-F530.
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.292
-
-
Chintapalli, J.1
Yang, S.2
Opawumi, D.3
Goyal, S.R.4
Shamsuddin, N.5
Malhotra, A.6
Reiss, K.7
Meggs, L.G.8
-
35
-
-
84875550716
-
Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway
-
Feng X., Liang N., Zhu D., Gao Q., Peng L., Dong H., Yue Q., Liu H., Bao L., Zhang J., Hao J., Gao Y., Yu X., Sun J. Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway. PLoS One 2013, 8:e59888.
-
(2013)
PLoS One
, vol.8
-
-
Feng, X.1
Liang, N.2
Zhu, D.3
Gao, Q.4
Peng, L.5
Dong, H.6
Yue, Q.7
Liu, H.8
Bao, L.9
Zhang, J.10
Hao, J.11
Gao, Y.12
Yu, X.13
Sun, J.14
|