Plasma lactate and diabetes risk in 8045 participants of the Atherosclerosis Risk in Communities Study

Annals of Epidemiology

Volumn 23, Issue 12, 2013, Pages 791-796.e4

  Juraschek, Stephen P ^a,b   Selvin, Elizabeth ^a,b,c   Miller, Edgar R ^a,b,c   Brancati, Frederick L ^a,b,c   Young, J Hunter ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

ARIC; Cohort; Diabetes risk; Lactate

Indexed keywords

GLUCOSE; INSULIN; LACTIC ACID;

ADULT; ARTICLE; ATHEROSCLEROSIS; COHORT ANALYSIS; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SELF REPORT; TELEPHONE INTERVIEW;

ARIC; COHORT; DIABETES RISK; LACTATE;

ADULT; AGED; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; COMMUNITY-BASED PARTICIPATORY RESEARCH; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INSULIN; INSULIN RESISTANCE; LACTIC ACID; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RESIDENCE CHARACTERISTICS; RISK FACTORS; UNITED STATES;

EID: 84888023695     PISSN: 10472797     EISSN: 18732585     Source Type: Journal    
DOI: 10.1016/j.annepidem.2013.09.005     Document Type: Article

References (54)

1. Pagel-Langenickel I., Bao J., Pang L., Sack M.N. The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance. Endocr Rev 2010, 31:25-51.
2. Simoneau J.A., Colberg S.R., Thaete F.L., Kelley D.E. Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB J 1995, 9:273-278.
3. Kelley D.E., Slasky B.S., Janosky J. Skeletal muscle density: effects of obesity and non-insulin-dependent diabetes mellitus. Am J Clin Nutr 1991, 54:509-515.
4. Del Prato S., Bonadonna R.C., Bonora E., Gulli G., Solini A., Shank M., et al. Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. JClin Invest 1993, 91:484-494.
5. Petersen K.F., Befroy D., Dufour S., Dziura J., Ariyan C., Rothman D.L., et al. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 2003, 300:1140-1142.
6. Kelley D.E., He J., Menshikova E.V., Ritov V.B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002, 51:2944-2950.
7. Menshikova E.V., Ritov V.B., Toledo F.G.S., Ferrell R.E., Goodpaster B.H., Kelley D.E. Effects of weight loss and physical activity on skeletal muscle mitochondrial function in obesity. Am J Physiol Endocrinol Metab 2005, 288:E818-E825.
8. Toledo F.G.S., Menshikova E.V., Azuma K., Radiková Z., Kelley C.A., Ritov V.B., et al. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008, 57:987-994.
9. Morino K., Petersen K.F., Dufour S., Befroy D., Frattini J., Shatzkes N., et al. Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. JClin Invest 2005, 115:3587-3593.
10. Sparks L.M., Xie H., Koza R.A., Mynatt R., Hulver M.W., Bray G.A., et al. Ahigh-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 2005, 54:1926-1933.
11. Patti M.E., Butte A.J., Crunkhorn S., Cusi K., Berria R., Kashyap S., et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 2003, 100:8466-8471.
12. Mootha V.K., Lindgren C.M., Eriksson K.-F., Subramanian A., Sihag S., Lehar J., et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003, 34:267-273.
13. Stump C.S., Short K.R., Bigelow M.L., Schimke J.M., Nair K.S. Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci USA 2003, 100:7996-8001.
14. Short K.R., Nair K.S., Stump C.S. Impaired mitochondrial activity and insulin-resistant offspring of patients with type 2 diabetes. NEngl J Med 2004, 350:2419-2421. author reply 2419-2421.
15. Petersen K.F., Dufour S., Befroy D., Garcia R., Shulman G.I. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. NEngl J Med 2004, 350:664-671.
16. Bruce C.R., Anderson M.J., Carey A.L., Newman D.G., Bonen A., Kriketos A.D., et al. Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. JClin Endocrinol Metab 2003, 88:5444-5451.
17. Lowell B.B., Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 2005, 307:384-387.
18. Wisløff U., Najjar S.M., Ellingsen O., Haram P.M., Swoap S., Al-Share Q., et al. Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science 2005, 307:418-420.
19. Eriksson K.F., Lindgärde F. Impaired glucose tolerance in a middle-aged male urban population: a new approach for identifying high-risk cases. Diabetologia 1990, 33:526-531.
20. Holloszy J.O. "Deficiency" of mitochondria in muscle does not cause insulin resistance. Diabetes 2013, 62:1036-1040.
21. Goodpaster B.H. Mitochondrial deficiency is associated with insulin resistance. Diabetes 2013, 62:1032-1035.
22. Perry C.G.R., Kane D.A., Lanza I.R., Neufer P.D. Methods for assessing mitochondrial function in diabetes. Diabetes 2013, 62:1041-1053.
23. Avogaro A., Toffolo G., Miola M., Valerio A., Tiengo A., Cobelli C., et al. Intracellular lactate- and pyruvate-interconversion rates are increased in muscle tissue of non-insulin-dependent diabetic individuals. JClin Invest 1996, 98:108-115.
24. Arieff A.I., Graf H. Pathophysiology of type A hypoxic lactic acidosis in dogs. Am J Physiol 1987, 253:E271-E276.
25. Lovejoy J., Newby F.D., Gebhart S.S., DiGirolamo M. Insulin resistance in obesity is associated with elevated basal lactate levels and diminished lactate appearance following intravenous glucose and insulin. Metab Clin Exp 1992, 41:22-27.
26. Reaven G.M., Hollenbeck C., Jeng C.Y., Wu M.S., Chen Y.D. Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 1988, 37:1020-1024.
27. Chen Y.D., Varasteh B.B., Reaven G.M. Plasma lactate concentration in obesity and type 2 diabetes. Diabete Metab 1993, 19:348-354.
28. Ohlson L.O., Larsson B., Björntorp P., Eriksson H., Svärdsudd K., Welin L., et al. Risk factors for type 2 (non-insulin-dependent) diabetes mellitus. Thirteen and one-half years of follow-up of the participants in a study of Swedish men born in 1913. Diabetologia 1988, 31:798-805.
29. Juraschek S.P., Shanta G.P.S., Chu A.Y., Miller E.R., Guallar E., Hoogeveen R.C., et al. Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study. PLoS ONE 2013, In press.
30. The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol 1989, 129:687-702.
31. Jackson R., Chambless L.E., Yang K., Byrne T., Watson R., Folsom A., et al. Differences between respondents and nonrespondents in a multicenter community-based study vary by gender ethnicity. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. JClin Epidemiol 1996, 49:1441-1446.
32. White A.D., Folsom A.R., Chambless L.E., Sharret A.R., Yang K., Conwill D., et al. Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years' experience. JClin Epidemiol 1996, 49:223-233.
33. Barham D., Trinder P. An improved colour reagent for the determination of blood glucose by the oxidase system. Analyst 1972, 97:142-145.
34. Bielinski S.J., Pankow J.S., Rasmussen-Torvik L.J., Bailey K., Li M., Selvin E., et al. Strength of association for incident diabetes risk factors according to diabetes case definitions: the Atherosclerosis Risk in Communities Study. American Journal of Epidemiology 2012, 10.1093/aje/kwr326.
35. Schneider ALC, Pankow JS, Heiss G, Selvin E. Validity and reliability of self-reported diabetes in the Atherosclerosis Risk in Communities (ARIC) Study 2012;In Press.
36. Duncan B.B., Schmidt M.I., Pankow J.S., Ballantyne C.M., Couper D., Vigo A., et al. Low-grade systemic inflammation and the development of type 2 diabetes:the atherosclerosis risk in communities study. Diabetes 2003, 52:1799-1805.
37. Schmidt M.I., Duncan B.B., Sharrett A.R., Lindberg G., Savage P.J., Offenbacher S., et al. Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet 1999, 353:1649-1652.
38. McLaughlin T., Abbasi F., Cheal K., Chu J., Lamendola C., Reaven G. Use of metabolic markers to identify overweight individuals who are insulin resistant. Ann Intern Med 2003, 139:802-809.
39. Ascaso J.F., Pardo S., Real J.T., Lorente R.I., Priego A., Carmena R. Diagnosing insulin resistance by simple quantitative methods in subjects with normal glucose metabolism. Diabetes Care 2003, 26:3320-3325.
40. Mizock B.A., Falk J.L. Lactic acidosis in critical illness. Crit Care Med 1992, 20:80-93.
41. Crawford S.O., Hoogeveen R.C., Brancati F.L., Astor B.C., Ballantyne C.M., Schmidt M.I., et al. Association of blood lactate with type 2 diabetes: the Atherosclerosis Risk in Communities Carotid MRI Study. Int J Epidemiol 2010, 39:1647-1655.
42. Perriello G., Jorde R., Nurjhan N., Stumvoll M., Dailey G., Jenssen T., et al. Estimation of glucose-alanine-lactate-glutamine cycles in postabsorptive humans: role of skeletal muscle. Am J Physiol 1995, 269:E443-E450.
43. Yki-Järvinen H., Bogardus C., Foley J.E. Regulation of plasma lactate concentration in resting human subjects. Metab Clin Exp 1990, 39:859-864.
44. Qvisth V., Hagström-Toft E., Moberg E., Sjöberg S., Bolinder J. Lactate release from adipose tissue and skeletal muscle invivo: defective insulin regulation in insulin-resistant obese women. Am J Physiol Endocrinol Metab 2007, 292:E709-E714.
45. Sandqvist M.M., Eriksson J.W., Jansson P.A. Increased lactate release per fat cell in normoglycemic first-degree relatives of individuals with type 2 diabetes. Diabetes 2001, 50:2344-2348.
46. Crandall D.L., Fried S.K., Francendese A.A., Nickel M., DiGirolamo M. Lactate release from isolated rat adipocytes: influence of cell size, glucose concentration, insulin and epinephrine. Horm Metab Res 1983, 15:326-329.
47. Ye J. Adipose tissue vascularization: its role in chronic inflammation. Curr Diab Rep 2011, 11:203-210.
48. Py G., Lambert K., Perez-Martin A., Raynaud E., Préfaut C., Mercier J. Impaired sarcolemmal vesicle lactate uptake and skeletal muscle MCT1 and MCT4 expression in obese Zucker rats. Am J Physiol Endocrinol Metab 2001, 281:E1308-E1315.
49. Iossa S., Mollica M.P., Lionetti L., Crescenzo R., Tasso R., Liverini G. Apossible link between skeletal muscle mitochondrial efficiency and age-induced insulin resistance. Diabetes 2004, 53:2861-2866.
50. Reardon W., Ross R.J., Sweeney M.G., Luxon L.M., Pembrey M.E., Harding A.E., et al. Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA. Lancet 1992, 340:1376-1379.
51. Van den Ouweland J.M., Lemkes H.H., Ruitenbeek W., Sandkuijl L.A., de Vijlder M.F., Struyvenberg P.A., et al. Mutation in mitochondrial tRNA(Leu)(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet 1992, 1:368-371.
52. Björntorp P., Scherstén T., Fagerberg S.E. Respiration and phosphorylation of mitochondria isolated from the skeletal muscle of diabetic and normal subjects. Diabetologia 1967, 3:346-352.
53. Kim J.Y., Hickner R.C., Cortright R.L., Dohm G.L., Houmard J.A. Lipid oxidation is reduced in obese human skeletal muscle. Am J Physiol Endocrinol Metab 2000, 279:E1039-E1044.
54. Hoeks J., van Herpen N.A., Mensink M., Moonen-Kornips E., van Beurden D., Hesselink M.K.C., et al. Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 2010, 59:2117-2125.