메뉴 건너뛰기




Volumn 98, Issue 1, 1996, Pages 108-115

Intracellular lactate- and pyruvate-interconversion rates are increased in muscle tissue of non-insulin-dependent diabetic individuals

Author keywords

forearm metabolism; lactate metabolism; non insulin dependent diabetes mellitus; pyruvate metabolism; stable isotopes

Indexed keywords

FATTY ACID; GLUCOSE; KETONE BODY; LACTIC ACID; PYRUVIC ACID;

EID: 0030035651     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118754     Document Type: Article
Times cited : (72)

References (45)
  • 1
    • 0024507794 scopus 로고
    • Fasting hyperglycemia in non-insulin dependent diabetes mellitus: Contribution of excessive hepatic glucose production and impaired tissue glucose uptake
    • DeFronzo, R.A., E. Ferrannini, and D.C. Simonson. 1989. Fasting hyperglycemia in non-insulin dependent diabetes mellitus: contribution of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism. 38: 387-395.
    • (1989) Metabolism , vol.38 , pp. 387-395
    • DeFronzo, R.A.1    Ferrannini, E.2    Simonson, D.C.3
  • 2
    • 0024511329 scopus 로고
    • Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
    • Consoli, A., N. Nurjahan, F. Capani, and J. Gerich. 1989. Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes. 38:550-558.
    • (1989) Diabetes , vol.38 , pp. 550-558
    • Consoli, A.1    Nurjahan, N.2    Capani, F.3    Gerich, J.4
  • 3
    • 0025630056 scopus 로고
    • Mechanism of increased gluconeogenesis in non-insulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism
    • Consoli, A., N. Nurjahan, J.J. Reilly, D.M. Bier, and J.E. Gerich. 1990. Mechanism of increased gluconeogenesis in non-insulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism. J. Clin. Invest. 86:2038-2045.
    • (1990) J. Clin. Invest. , vol.86 , pp. 2038-2045
    • Consoli, A.1    Nurjahan, N.2    Reilly, J.J.3    Bier, D.M.4    Gerich, J.E.5
  • 4
    • 0024392514 scopus 로고
    • Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus: Evidence for multiple sites of insulin resistance
    • Groop, L., R.C. Bonadonna, S. Del Prato, K. Ratheiser, K. Zick, E. Ferrannini, and R.A. DeFronzo. 1989. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus: evidence for multiple sites of insulin resistance. J. Clin. Invest. 84:205-213.
    • (1989) J. Clin. Invest. , vol.84 , pp. 205-213
    • Groop, L.1    Bonadonna, R.C.2    Del Prato, S.3    Ratheiser, K.4    Zick, K.5    Ferrannini, E.6    DeFronzo, R.A.7
  • 5
    • 0023873229 scopus 로고
    • Increased rate of Cori cycle in obese subjects with NIDDM and effect of weight reduction
    • Zawadzki, J.K., R.R. Wolfe, D.M. Mott, S. Lillioja, B. Howard, and C. Bogardus. 1988. Increased rate of Cori cycle in obese subjects with NIDDM and effect of weight reduction. Diabetes. 37:154-159.
    • (1988) Diabetes , vol.37 , pp. 154-159
    • Zawadzki, J.K.1    Wolfe, R.R.2    Mott, D.M.3    Lillioja, S.4    Howard, B.5    Bogardus, C.6
  • 6
    • 0027500242 scopus 로고
    • Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus
    • Del Prato, S., R.C. Bonadonna, E. Bonora, G. Gulli, A. Solini, M. Shank, and R.A. DeFronzo. 1993. Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. J. Clin. Invest. 91:484-494.
    • (1993) J. Clin. Invest. , vol.91 , pp. 484-494
    • Del Prato, S.1    Bonadonna, R.C.2    Bonora, E.3    Gulli, G.4    Solini, A.5    Shank, M.6    DeFronzo, R.A.7
  • 8
    • 0019762341 scopus 로고
    • The effect of insulin on the disposal of intravenous glucose: Results from indirect calorimetry and hepatic and femoral vein catheterization
    • DeFronzo, R.A., E. Jacot, E. Jequier, E. Maeder, and P. Felber. 1981. The effect of insulin on the disposal of intravenous glucose: results from indirect calorimetry and hepatic and femoral vein catheterization. Diabetes. 30:1000-1007.
    • (1981) Diabetes , vol.30 , pp. 1000-1007
    • Defronzo, R.A.1    Jacot, E.2    Jequier, E.3    Maeder, E.4    Felber, P.5
  • 9
    • 0025167623 scopus 로고
    • Glucose and gluconeogenic substrate exchange by the forearm skeletal muscle in hyperglycemic and insulin-treated type II diabetic patients
    • Capaldo, B., R. Napoli, P. Di Bonito, G. Albano, and L. Saccá. 1990. Glucose and gluconeogenic substrate exchange by the forearm skeletal muscle in hyperglycemic and insulin-treated type II diabetic patients. J. Clin. Endocrinol. Metab. 71:1220-1223.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , pp. 1220-1223
    • Capaldo, B.1    Napoli, R.2    Di Bonito, P.3    Albano, G.4    Saccá, L.5
  • 10
    • 0025162987 scopus 로고
    • Contribution of liver and skeletal muscle to alanine and lactate metabolism in humans
    • Consoli, A., N. Nurjahan, J.J. Reilly, D.M. Bier, and J.E. Gerich. 1990. Contribution of liver and skeletal muscle to alanine and lactate metabolism in humans. Am. J. Physiol. 259:E677-E684.
    • (1990) Am. J. Physiol. , vol.259
    • Consoli, A.1    Nurjahan, N.2    Reilly, J.J.3    Bier, D.M.4    Gerich, J.E.5
  • 11
    • 0026717602 scopus 로고
    • The use of isotopes gone astray
    • Landau, B.R., and J. Wahren. 1992. The use of isotopes gone astray. Metabolism. 41:457-459.
    • (1992) Metabolism , vol.41 , pp. 457-459
    • Landau, B.R.1    Wahren, J.2
  • 12
    • 0027466920 scopus 로고
    • Ketone and lactate metabolism: An exchange of conclusions
    • Landau, B.R. 1993. Ketone and lactate metabolism: an exchange of conclusions. Metabolism. 42:260-262.
    • (1993) Metabolism , vol.42 , pp. 260-262
    • Landau, B.R.1
  • 13
    • 16744363341 scopus 로고
    • Lactate production cannot be measured with tracer techniques
    • Sahlin, K. 1987. Lactate production cannot be measured with tracer techniques. Am. J. Physiol. 252:E439-E440.
    • (1987) Am. J. Physiol. , vol.252
    • Sahlin, K.1
  • 15
    • 1842278494 scopus 로고
    • The source of blood samples withdrawn from deep forearm vein via catheters passed upstream from median cubital vein
    • Coles, D.R., K.E. Cooper, R.F. Mottram, and O.V. Occleshaw. 1958. The source of blood samples withdrawn from deep forearm vein via catheters passed upstream from median cubital vein. J. Physiol. (Lond.). 142:258-267.
    • (1958) J. Physiol. (Lond.) , vol.142 , pp. 258-267
    • Coles, D.R.1    Cooper, K.E.2    Mottram, R.F.3    Occleshaw, O.V.4
  • 16
    • 0023930822 scopus 로고
    • The theoretical basis of indirect calorimetry: A review
    • Ferrannini, E. 1988. The theoretical basis of indirect calorimetry: a review. Metab. Clin. Exp. 37:287-301.
    • (1988) Metab. Clin. Exp. , vol.37 , pp. 287-301
    • Ferrannini, E.1
  • 17
    • 0018087782 scopus 로고
    • Enzymic fluorometric continuous flow assays for blood glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate
    • Lloyd, B., J. Burrin, P. Smythe, and K.G.M.M. Alberti. 1978. Enzymic fluorometric continuous flow assays for blood glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate. Clin. Chem. 34:1727-1729.
    • (1978) Clin. Chem. , vol.34 , pp. 1727-1729
    • Lloyd, B.1    Burrin, J.2    Smythe, P.3    Alberti, K.G.M.M.4
  • 18
    • 0018611178 scopus 로고
    • Enzymatic microdetermination of serum free fatty acids
    • Shimuzu, S., K. Inque, Y. Tani, and H. Yamada. 1979. Enzymatic microdetermination of serum free fatty acids. Anal. Biochem. 98:341-345.
    • (1979) Anal. Biochem. , vol.98 , pp. 341-345
    • Shimuzu, S.1    Inque, K.2    Tani, Y.3    Yamada, H.4
  • 21
    • 0001340161 scopus 로고
    • Importance of hematocrit in interpretation of blood sugar
    • Dillion, R. 1965. Importance of hematocrit in interpretation of blood sugar. Diabetes. 14:672-678.
    • (1965) Diabetes , vol.14 , pp. 672-678
    • Dillion, R.1
  • 23
    • 0026769254 scopus 로고
    • Tracer-to-tracee ratio for analysis of stable isotope tracer data: Link with radioactive kinetic formalism
    • Cobelli, C., G. Toffolo, and D. Foster. 1992 Tracer-to-tracee ratio for analysis of stable isotope tracer data: link with radioactive kinetic formalism. Am. J. Physiol. 262:E968-E975.
    • (1992) Am. J. Physiol. , vol.262
    • Cobelli, C.1    Toffolo, G.2    Foster, D.3
  • 25
    • 0026794559 scopus 로고
    • V-A and A-V modes in whole body and regional kinetics: Domain of validity from a physiological model
    • Saccá, L., G. Toffolo, and C. Cobelli. 1992. V-A and A-V modes in whole body and regional kinetics: domain of validity from a physiological model. Am. J. Physiol. 263:E597-E606.
    • (1992) Am. J. Physiol. , vol.263
    • Saccá, L.1    Toffolo, G.2    Cobelli, C.3
  • 26
    • 0028156379 scopus 로고
    • Measurements of pyruvate and lactate kinetics across the hindlimb and gut of anesthetized dogs
    • Chinkes, D.L., X.J. Zhang, J.A. Romijn, Y. Sakurai, and R.R. Wolfe. 1994. Measurements of pyruvate and lactate kinetics across the hindlimb and gut of anesthetized dogs. Am. J. Physiol. 257:E174-E182.
    • (1994) Am. J. Physiol. , vol.257
    • Chinkes, D.L.1    Zhang, X.J.2    Romijn, J.A.3    Sakurai, Y.4    Wolfe, R.R.5
  • 27
    • 0029025630 scopus 로고
    • Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats
    • Large, V., M. Solovieiv, H. Brunengraber, and M. Beylot. 1995. Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats. Am. J. Physiol. 268:E880-E888.
    • (1995) Am. J. Physiol. , vol.268
    • Large, V.1    Solovieiv, M.2    Brunengraber, H.3    Beylot, M.4
  • 29
    • 0023153344 scopus 로고
    • Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in non-insulin dependent diabetes mellitus
    • Chen, Y.-I., A. Golay, A.L.M. Swislocki, and G.M. Reaven. 1987. Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in non-insulin dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 64:17-21.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 17-21
    • Chen, Y.-I.1    Golay, A.2    Swislocki, A.L.M.3    Reaven, G.M.4
  • 31
    • 50549202600 scopus 로고
    • The glucose fatty acid cycle; its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle, J.P., P.B. Garland, and E.A. Newsholme. 1963. The glucose fatty acid cycle; its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. i:785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, J.P.1    Garland, P.B.2    Newsholme, E.A.3
  • 32
    • 0026598750 scopus 로고
    • Hyperglycemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus
    • Vaag, A., P. Damsbo, O. Hoter-Nielsen, and H. Beck-Nielsen. 1992. Hyperglycemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 35: 80-88.
    • (1992) Diabetologia , vol.35 , pp. 80-88
    • Vaag, A.1    Damsbo, P.2    Hoter-Nielsen, O.3    Beck-Nielsen, H.4
  • 34
    • 0025883960 scopus 로고
    • Muscle lactate transport studied in sarcolemmal giant vescicles: Dependence on fibre type and age
    • Juel, C., A. Honig, and H. Pilegaard. 1991. Muscle lactate transport studied in sarcolemmal giant vescicles: dependence on fibre type and age. Acta Physiol. Scand. 143:361-365.
    • (1991) Acta Physiol. Scand. , vol.143 , pp. 361-365
    • Juel, C.1    Honig, A.2    Pilegaard, H.3
  • 36
    • 0025162987 scopus 로고
    • Contribution of liver and skeletal muscle to alanine and lactate metabolism in humans
    • Consoli, A., N. Nurjahan, J. Reilly, D.M. Bier, and J.E. Gerich. 1990. Contribution of liver and skeletal muscle to alanine and lactate metabolism in humans. Am. J. Physiol. 259:E677-E684.
    • (1990) Am. J. Physiol. , vol.259
    • Consoli, A.1    Nurjahan, N.2    Reilly, J.3    Bier, D.M.4    Gerich, J.E.5
  • 37
    • 0026512255 scopus 로고
    • Skeletal muscle is a major site of lactate uptake and release during hyperinsulinemia
    • Consoli, A., N. Nurjahan, J.E. Gerich, and L.J. Mandarino. 1992. Skeletal muscle is a major site of lactate uptake and release during hyperinsulinemia. Metabolism. 41:176-179.
    • (1992) Metabolism , vol.41 , pp. 176-179
    • Consoli, A.1    Nurjahan, N.2    Gerich, J.E.3    Mandarino, L.J.4
  • 38
    • 0025113256 scopus 로고
    • Regulation of plasma lactate concentration in resting human subjects
    • Yki-Jarvinen, H., C. Bogardus, and J.E. Foley. 1990. Regulation of plasma lactate concentration in resting human subjects. Metabolism. 39:859-864.
    • (1990) Metabolism , vol.39 , pp. 859-864
    • Yki-Jarvinen, H.1    Bogardus, C.2    Foley, J.E.3
  • 39
    • 0026322590 scopus 로고
    • Glycerol and lactate uptake in human forearm
    • Frayn, K.N., S.W. Coppack, and S.M. Humphreys. 1991. Glycerol and lactate uptake in human forearm. Metabolism. 40:1317-1319.
    • (1991) Metabolism , vol.40 , pp. 1317-1319
    • Frayn, K.N.1    Coppack, S.W.2    Humphreys, S.M.3
  • 40
    • 0022537566 scopus 로고
    • Impact of glucose ingestion on hepatic and peripheral glucose metabolism in man: An analysis based on simultaneous use of the forearm and double isotope techniques
    • Jackson, R.A., R.D. Roshania, M.I. Hawa, B.M. Sim, and L. Di Silvio. 1986. Impact of glucose ingestion on hepatic and peripheral glucose metabolism in man: an analysis based on simultaneous use of the forearm and double isotope techniques. J. Clin. Endocrinol. Metab. 63:541-549.
    • (1986) J. Clin. Endocrinol. Metab. , vol.63 , pp. 541-549
    • Jackson, R.A.1    Roshania, R.D.2    Hawa, M.I.3    Sim, B.M.4    Di Silvio, L.5
  • 41
    • 0015517384 scopus 로고
    • Glucose-lactate interrelations in man
    • Kreisberg, R.A. 1972. Glucose-lactate interrelations in man. N. Engl. J. Med. 287:132-137.
    • (1972) N. Engl. J. Med. , vol.287 , pp. 132-137
    • Kreisberg, R.A.1
  • 42
    • 0024551026 scopus 로고
    • Metabolic characteristics of human adipose tissue in vivo
    • Frayn, K.N., S.W. Coppak, S.M. Humphreys, and P.L. Whyte. 1989. Metabolic characteristics of human adipose tissue in vivo. Clin. Sci. 76:509-516.
    • (1989) Clin. Sci. , vol.76 , pp. 509-516
    • Frayn, K.N.1    Coppak, S.W.2    Humphreys, S.M.3    Whyte, P.L.4
  • 43
    • 0025217709 scopus 로고
    • Evidence for lactate production by human adipose tissue in vivo
    • Jansson, P.-A., U. Smith, and P. Lönnroth. 1990. Evidence for lactate production by human adipose tissue in vivo. Diabetologia. 33:253-256.
    • (1990) Diabetologia , vol.33 , pp. 253-256
    • Jansson, P.-A.1    Smith, U.2    Lönnroth, P.3
  • 44
    • 0025311024 scopus 로고
    • Subcutaneous adipose tissue: A source of lactate production after glucose in humans
    • Hagström, E., P. Arner, U. Ungerstedt, and J. Bounder. 1990. Subcutaneous adipose tissue: a source of lactate production after glucose in humans. Am. J. Physiol. 258:E888-E893.
    • (1990) Am. J. Physiol. , vol.258
    • Hagström, E.1    Arner, P.2    Ungerstedt, U.3    Bounder, J.4
  • 45
    • 0027954996 scopus 로고
    • Lactate release from the subcutaneous tissue in lean and obese men
    • Jansson, P.-A., A. Larsson, U. Smith, and P. Lönnroth. 1994. Lactate release from the subcutaneous tissue in lean and obese men. J. Clin. Invest. 93: 240-246.
    • (1994) J. Clin. Invest. , vol.93 , pp. 240-246
    • Jansson, P.-A.1    Larsson, A.2    Smith, U.3    Lönnroth, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.