-
1
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
1:CAS:528:DC%2BD38Xjt1ersb4%3D
-
Karsenty G, Wagner EF (2002) Reaching a genetic and molecular understanding of skeletal development. Cell 2:389-406
-
(2002)
Cell
, vol.2
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
2
-
-
0037673933
-
Control of osteoblast function and regulation of bone mass
-
12748654 10.1038/nature01660 1:CAS:528:DC%2BD3sXjs1ynu7Y%3D
-
Harada S, Rodan GA (2003) Control of osteoblast function and regulation of bone mass. Nature 423:349-355
-
(2003)
Nature
, vol.423
, pp. 349-355
-
-
Harada, S.1
Rodan, G.A.2
-
3
-
-
0034455103
-
Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
-
10782361 10.1210/er.21.2.115 1:STN:280:DC%2BD3c3ksVaiug%3D%3D
-
Manolagas SC (2000) Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 21:115-137
-
(2000)
Endocr Rev
, vol.21
, pp. 115-137
-
-
Manolagas, S.C.1
-
4
-
-
0033005366
-
Eukaryotic initiation factor eIF2
-
10.1016/S1357-2725(98)00128-9 1:CAS:528:DyaK1MXhvFSlu70%3D
-
Kimball SC (1999) Eukaryotic initiation factor eIF2. Int J Biochem 31:25-39
-
(1999)
Int J Biochem
, vol.31
, pp. 25-39
-
-
Kimball, S.C.1
-
5
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
11106749 10.1016/S1097-2765(00)00108-8 1:CAS:528:DC%2BD3cXosV2mtrs%3D
-
Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6:1099-1108
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
6
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; Implication for Coffin-Lowry Syndrome
-
15109498 10.1016/S0092-8674(04)00344-7 1:CAS:528:DC%2BD2cXjvFemtro%3D
-
Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G (2004) ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117:387-398
-
(2004)
Cell
, vol.117
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
Hanauer, A.11
Karsenty, G.12
-
7
-
-
34247121035
-
Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling
-
17418825 10.1016/j.febslet.2007.03.063 1:CAS:528:DC%2BD2sXksV2rtr8%3D
-
Hamamura K, Yokota H (2007) Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling. FEBS Lett 581:1769-1774
-
(2007)
FEBS Lett
, vol.581
, pp. 1769-1774
-
-
Hamamura, K.1
Yokota, H.2
-
8
-
-
84868206080
-
Salubrinal promotes healing of surgical wounds in rat femurs
-
22610062 10.1007/s00774-012-0359-z
-
Zhang P, Hamamura K, Jiang C, Zhao L, Yokota H (2012) Salubrinal promotes healing of surgical wounds in rat femurs. J Bone Miner Metab 30:568-579
-
(2012)
J Bone Miner Metab
, vol.30
, pp. 568-579
-
-
Zhang, P.1
Hamamura, K.2
Jiang, C.3
Zhao, L.4
Yokota, H.5
-
9
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
10.1073/pnas.95.7.3597
-
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, et al. (1988) Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95:3597-3602
-
(1988)
Proc Natl Acad Sci USA
, vol.95
, pp. 3597-3602
-
-
Yasuda, H.1
Shima, N.2
Nakagawa, N.3
Yamaguchi, K.4
Kinosaki, M.5
-
10
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
9568710 10.1016/S0092-8674(00)81569-X 1:CAS:528:DyaK1cXivVyhtrg%3D
-
Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR et al (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
-
11
-
-
41949089764
-
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
-
18089564 10.1074/jbc.M705092200 1:CAS:528:DC%2BD1cXit1Omurw%3D
-
Robling AG, Niziolek PJ, Baldridge LA, Condon KW, Allen MR, Alam I, Mantila SM, Gluhak-Heinrich J, Bellido TM, Harris SE, Turner CH (2008) Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem 283:5866-5875
-
(2008)
J Biol Chem
, vol.283
, pp. 5866-5875
-
-
Robling, A.G.1
Niziolek, P.J.2
Baldridge, L.A.3
Condon, K.W.4
Allen, M.R.5
Alam, I.6
Mantila, S.M.7
Gluhak-Heinrich, J.8
Bellido, T.M.9
Harris, S.E.10
Turner, C.H.11
-
12
-
-
84888006884
-
Loading- and unloading-driven regulation of phosphorylation of eIF2α
-
10.2187/bss.25.3 1:CAS:528:DC%2BC3MXhtFWmtLnK
-
Zhang P, Jiang C, Ledet E, Yokota H (2011) Loading- and unloading-driven regulation of phosphorylation of eIF2α. Biol Sci Space 25:3-6
-
(2011)
Biol Sci Space
, vol.25
, pp. 3-6
-
-
Zhang, P.1
Jiang, C.2
Ledet, E.3
Yokota, H.4
-
13
-
-
13644256191
-
A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress
-
15705855 10.1126/science.1101902 1:CAS:528:DC%2BD2MXhtFWmsL0%3D
-
Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J (2005) A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress. Science 307:935-939
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
Yuan, J.11
-
14
-
-
79953288480
-
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
-
21385720 10.1126/science.1201396 1:CAS:528:DC%2BC3MXjvVyisbw%3D
-
Tsaytler P, Harding HP, Ron D, Bertolotti A (2011) Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 332:91-94
-
(2011)
Science
, vol.332
, pp. 91-94
-
-
Tsaytler, P.1
Harding, H.P.2
Ron, D.3
Bertolotti, A.4
-
15
-
-
0029133135
-
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
-
8686503 10.1002/jbmr.5650101008 1:CAS:528:DyaK2MXpsFGmsbo%3D
-
Hughes DE, Wright KR, Uy HL, Sasaki A, Yoneda T, Roodman GD, Mundy GR, Boyce BF (1995) Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo. J Bone Miner Res 10:1478-1487
-
(1995)
J Bone Miner Res
, vol.10
, pp. 1478-1487
-
-
Hughes, D.E.1
Wright, K.R.2
Uy, H.L.3
Sasaki, A.4
Yoneda, T.5
Roodman, G.D.6
Mundy, G.R.7
Boyce, B.F.8
-
16
-
-
80054683416
-
Increased bone mass in mice after single injection of anti-receptor activator of nuclear factor-κB ligand-neutralizing antibody
-
21862583 10.1074/jbc.M111.246280 1:CAS:528:DC%2BC3MXhtlSqtLvE
-
Furuya Y, Mori K, Ninomiya T, Tomimori Y, Tanaka S, Takahashi N, Udagawa N, Uchida K, Yasuda H (2011) Increased bone mass in mice after single injection of anti-receptor activator of nuclear factor-κB ligand-neutralizing antibody. J Biol Chem 286:37023-37031
-
(2011)
J Biol Chem
, vol.286
, pp. 37023-37031
-
-
Furuya, Y.1
Mori, K.2
Ninomiya, T.3
Tomimori, Y.4
Tanaka, S.5
Takahashi, N.6
Udagawa, N.7
Uchida, K.8
Yasuda, H.9
-
17
-
-
0020678843
-
In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
-
6826647 10.1083/jcb.96.1.191 1:CAS:528:DyaL3sXmvFKmtA%3D%3D
-
Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S (1983) In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96:191-198
-
(1983)
J Cell Biol
, vol.96
, pp. 191-198
-
-
Sudo, H.1
Kodama, H.A.2
Amagai, Y.3
Yamamoto, S.4
Kasai, S.5
-
18
-
-
0033787375
-
Cloning, sequencing, and functional characterization of the rat homologue of receptor activator of NF-kappaB ligand
-
11092398 10.1359/jbmr.2000.15.11.2178 1:CAS:528:DC%2BD3cXnvVKlt7c%3D
-
Xu J, Tan JW, Gao XH, Laird R, Liu D, Wysocki S, Zheng MH (2000) Cloning, sequencing, and functional characterization of the rat homologue of receptor activator of NF-kappaB ligand. J Bone Miner Res 15:2178-2186
-
(2000)
J Bone Miner Res
, vol.15
, pp. 2178-2186
-
-
Xu, J.1
Tan, J.W.2
Gao, X.H.3
Laird, R.4
Liu, D.5
Wysocki, S.6
Zheng, M.H.7
-
19
-
-
0142249497
-
Signaling in osteoclasts and the role of Fos/AP1 proteins
-
14532157 10.1136/ard.62.suppl-2.ii83 1:CAS:528:DC%2BD3sXpvVyjtb4%3D
-
Wagner EF, Matsuo K (2003) Signaling in osteoclasts and the role of Fos/AP1 proteins. Ann Rheum Dis 62:ii83-ii85
-
(2003)
Ann Rheum Dis
, vol.62
-
-
Wagner, E.F.1
Matsuo, K.2
-
20
-
-
0023233953
-
Osteoclast generation from human fetal bone marrow in cocultures with murine fetal long bones. A model for in vitro study of human osteoclast formation and function
-
3621288 10.1007/BF00215426 1:STN:280:DyaL2szgtFKitQ%3D%3D
-
Helfrich MH, Thesingh CW, Mieremet RH, van Iperen-van Gent AS (1987) Osteoclast generation from human fetal bone marrow in cocultures with murine fetal long bones. A model for in vitro study of human osteoclast formation and function. Cell Tissue Res 249:125-136
-
(1987)
Cell Tissue Res
, vol.249
, pp. 125-136
-
-
Helfrich, M.H.1
Thesingh, C.W.2
Mieremet, R.H.3
Van Iperen-Van Gent, A.S.4
-
21
-
-
0037148508
-
A novel member of the leukocyte receptor complex regulates osteoclast differentiation
-
11805147 1:CAS:528:DC%2BD38XosFCnsw%3D%3D
-
Kim N, Takami M, Rho J, Josien R, Choi Y (2002) A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J Exp Med 195:201-209
-
(2002)
J Exp Med
, vol.195
, pp. 201-209
-
-
Kim, N.1
Takami, M.2
Rho, J.3
Josien, R.4
Choi, Y.5
-
22
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
12479813 10.1016/S1534-5807(02)00369-6 1:CAS:528:DC%2BD38XpslClsL8%3D
-
Takayanagi H, Kim S, Koga T, Nishina H, Isshiki M, Yoshida H, Saiura A, Isobe M, Yokochi T, Inoue J, Wagner EF, Mak TW, Kodama T, Taniguchi T (2002) Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 3:889-901
-
(2002)
Dev Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
23
-
-
52949151942
-
IGF2-driven PI3 kinase and TGFβ signaling pathways in chondrogenesis
-
18675921 10.1016/j.cellbi.2008.07.007 1:CAS:528:DC%2BD1cXhtF2rsL%2FP
-
Hamamura K, Zhang P, Yokota H (2008) IGF2-driven PI3 kinase and TGFβ signaling pathways in chondrogenesis. Cell Biol Int 32:1238-1246
-
(2008)
Cell Biol Int
, vol.32
, pp. 1238-1246
-
-
Hamamura, K.1
Zhang, P.2
Yokota, H.3
-
24
-
-
0017182862
-
Guanabenz effects on blood pressure and noninvasive parameters of cardiac performance in patients with hypertension
-
773584 1:STN:280:DyaE287os1Ojtw%3D%3D
-
Shah RS, Walker BR, Vanov SK, Helfant RH (1976) Guanabenz effects on blood pressure and noninvasive parameters of cardiac performance in patients with hypertension. Clin Pharmacol Ther 19:732-737
-
(1976)
Clin Pharmacol Ther
, vol.19
, pp. 732-737
-
-
Shah, R.S.1
Walker, B.R.2
Vanov, S.K.3
Helfant, R.H.4
-
25
-
-
0021710185
-
Osteocalcin
-
6334818 1:CAS:528:DyaL2MXns1Oquw%3D%3D
-
Galli M, Caniggia M (1984) Osteocalcin. Minerva Med 75:2489-2501
-
(1984)
Minerva Med
, vol.75
, pp. 2489-2501
-
-
Galli, M.1
Caniggia, M.2
-
26
-
-
0033962845
-
Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increase rate of bone turnover
-
10646119 10.1359/jbmr.2000.15.1.103 1:CAS:528:DC%2BD3cXmsVyguw%3D%3D
-
Angel NZ, Walsh N, Forwood MR, Ostrowski MC, Cassady AI, Hume DA (2000) Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increase rate of bone turnover. J Bone Miner Res 15:103-110
-
(2000)
J Bone Miner Res
, vol.15
, pp. 103-110
-
-
Angel, N.Z.1
Walsh, N.2
Forwood, M.R.3
Ostrowski, M.C.4
Cassady, A.I.5
Hume, D.A.6
-
27
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
22733998 10.1083/jcb.201110131 1:CAS:528:DC%2BC38XpvFOmu7Y%3D
-
Wang S, Kaufman RJ (2012) The impact of the unfolded protein response on human disease. J Cell Biol 197:857-867
-
(2012)
J Cell Biol
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
28
-
-
0034613188
-
Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappaB ligand (RANKL)
-
10859303 10.1074/jbc.M001229200 1:CAS:528:DC%2BD3cXntlCisL4%3D
-
Matsumoto M, Sudo T, Saito T, Osada H, Tsujimoto M (2000) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappaB ligand (RANKL). J Biol Chem 275:31155-31161
-
(2000)
J Biol Chem
, vol.275
, pp. 31155-31161
-
-
Matsumoto, M.1
Sudo, T.2
Saito, T.3
Osada, H.4
Tsujimoto, M.5
-
29
-
-
0035808458
-
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways
-
11032840 10.1074/jbc.M008198200 1:CAS:528:DC%2BD3MXmtFSquw%3D%3D
-
Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A, Abu-Amer Y (2001) Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem 276:563-568
-
(2001)
J Biol Chem
, vol.276
, pp. 563-568
-
-
Zhang, Y.H.1
Heulsmann, A.2
Tondravi, M.M.3
Mukherjee, A.4
Abu-Amer, Y.5
-
30
-
-
34147132897
-
MafB negatively regulates RANKL-mediated osteoclast differentiation
-
17158225 10.1182/blood-2006-09-048249 1:CAS:528:DC%2BD2sXksFWitbY%3D
-
Kim K, Kim JH, Lee J, Jin HM, Kook H, Kim KK, Lee SY, Kim N (2007) MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood 109:3253-3259
-
(2007)
Blood
, vol.109
, pp. 3253-3259
-
-
Kim, K.1
Kim, J.H.2
Lee, J.3
Jin, H.M.4
Kook, H.5
Kim, K.K.6
Lee, S.Y.7
Kim, N.8
-
31
-
-
69949148448
-
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis
-
19718038 10.1038/nm.2007 1:CAS:528:DC%2BD1MXhtVKhs7vP
-
Zhao B, Takami M, Yamada A, Wang X, Koga T, Hu X, Tamura T, Ozato K, Choi Y, Ivashkiv LB, Takayanagi H, Kamijo R (2009) Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nat Med 15:1066-1071
-
(2009)
Nat Med
, vol.15
, pp. 1066-1071
-
-
Zhao, B.1
Takami, M.2
Yamada, A.3
Wang, X.4
Koga, T.5
Hu, X.6
Tamura, T.7
Ozato, K.8
Choi, Y.9
Ivashkiv, L.B.10
Takayanagi, H.11
Kamijo, R.12
-
32
-
-
77951074209
-
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis
-
20368579 10.1084/jem.20091957 1:CAS:528:DC%2BC3cXkvFGrs7s%3D
-
Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R et al (2010) The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med 207:751-762
-
(2010)
J Exp Med
, vol.207
, pp. 751-762
-
-
Miyauchi, Y.1
Ninomiya, K.2
Miyamoto, H.3
Sakamoto, A.4
Iwasaki, R.5
-
33
-
-
84875538389
-
MiR-29b negatively regulates human osteoclastic cell differentiation and function: Implications for the treatment of multiple myeloma-related bone disease
-
(in press)
-
Rossi M, Pitari MR, Amodio N, Di Martino MT, Conforti F, Leone E, Botta C, Paolino FM, Del Giudice T, Iuliano E, Caraglia M, Ferrarini M, Giordano A, Tagliaferri P, Tassone P (2012) miR-29b negatively regulates human osteoclastic cell differentiation and function: implications for the treatment of multiple myeloma-related bone disease. J Cell Physiol (in press)
-
(2012)
J Cell Physiol
-
-
Rossi, M.1
Pitari, M.R.2
Amodio, N.3
Di Martino, M.T.4
Conforti, F.5
Leone, E.6
Botta, C.7
Paolino, F.M.8
Del Giudice, T.9
Iuliano, E.10
Caraglia, M.11
Ferrarini, M.12
Giordano, A.13
Tagliaferri, P.14
Tassone, P.15
-
34
-
-
80055018787
-
Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1
-
Yasui T, Hirose J, Tsutsumi S, Nakamura K, Aburatani H, Tanaka S (2011) Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1. J Bone Miner Res 26:2655-2671
-
(2011)
J Bone Miner Res
, vol.26
, pp. 2655-2671
-
-
Yasui, T.1
Hirose, J.2
Tsutsumi, S.3
Nakamura, K.4
Aburatani, H.5
Tanaka, S.6
-
35
-
-
84870802028
-
Osteoporosis regulation by salubrinal through eIF2α mediated differentiation of osteoclast and osteoblast
-
23178987 10.1016/j.cellsig.2012.11.015 1:CAS:528:DC%2BC38XhvFWhsbjJ
-
He L, Lee J, Jang JH, Sakchaisri K, Hwang JS, Cha-Molstad HJ, Kim KA, Ryoo IJ, Lee HG, Kim SO, Soung NK, Lee KS, Kwon YT, Erikson RL, Ahn JS, Kim BY (2013) Osteoporosis regulation by salubrinal through eIF2α mediated differentiation of osteoclast and osteoblast. Cell Signal 25:552-560
-
(2013)
Cell Signal
, vol.25
, pp. 552-560
-
-
He, L.1
Lee, J.2
Jang, J.H.3
Sakchaisri, K.4
Hwang, J.S.5
Cha-Molstad, H.J.6
Kim, K.A.7
Ryoo, I.J.8
Lee, H.G.9
Kim, S.O.10
Soung, N.K.11
Lee, K.S.12
Kwon, Y.T.13
Erikson, R.L.14
Ahn, J.S.15
Kim, B.Y.16
|