Desmethyl macrolides: Synthesis and evaluation of 4,8,10-tridesmethyl cethromycin

ACS Medicinal Chemistry Letters

Volumn 4, Issue 11, 2013, Pages 1114-1118

  Wagh, Bharat ^a   Paul, Tapas ^a   Debrosse, Charles ^a   Klepacki, Dorota ^b   Small, Meagan C ^c   Mackerell, Alexander D ^c   Andrade, Rodrigo B ^a  

^a Temple University   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

antibiotic resistance; cethromycin; desmethyl analogues; ketolide antibiotics; molecular modeling; telithromycin; Total synthesis

Indexed keywords

4,8,10 TRIDESMETHYL CETHROMYCIN; MACROLIDE; METHYL GROUP; OXAZOLIDINONE DERIVATIVE; TELITHROMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CARBAMOYLATION; DRUG CONFORMATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MODEL; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 84887986443     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400337t     Document Type: Article

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