Desmethyl macrolides: Synthesis and evaluation of 4,8-didesmethyl telithromycin

ACS Medicinal Chemistry Letters

Volumn 3, Issue 12, 2012, Pages 1013-1018

  Wagh, Bharat ^a   Paul, Tapas ^a   Glassford, Ian ^a   Debrosse, Charles ^a   Klepacki, Dorota ^b   Small, Meagan C ^c   MacKerell, Alexander D ^c   Andrade, Rodrigo B ^a  

^a Temple University   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

antibiotic resistance; desmethyl analogues; ketolide antibiotics; molecular modeling; telithromycin; total synthesis

Indexed keywords

4,10 DINORTELITHROMYCIN; 4,8 DINORTELITHROMYCIN; 4,8,10 TRINORTELITHROMYCIN; ERYTHROMYCIN DERIVATIVE; MACROLIDE; TELITHROMYCIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARCHAEON; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL;

EID: 84871249030     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300230h     Document Type: Article

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