메뉴 건너뛰기




Volumn 2, Issue 11, 2013, Pages 635-642

Sequence, cloning, and analysis of the fluvirucin B1 polyketide synthase from actinomadura vulgaris

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; FLUVIRUCIN B1; HYDROLYASE; LACTAM DERIVATIVE; OXIDOREDUCTASE; POLYKETIDE SYNTHASE; THIOL ESTER HYDROLASE; UNCLASSIFIED DRUG;

EID: 84887944057     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb4000355     Document Type: Article
Times cited : (18)

References (38)
  • 3
    • 0034887171 scopus 로고    scopus 로고
    • Polyketide biosynthesis: A millennium review
    • Staunton, J. and Weissman, K. J. (2001) Polyketide biosynthesis: A millennium review Nat. Prod. Rep. 18, 380-416
    • (2001) Nat. Prod. Rep. , vol.18 , pp. 380-416
    • Staunton, J.1    Weissman, K.J.2
  • 4
    • 0034552096 scopus 로고    scopus 로고
    • Natural product biosynthesis: A new interface between enzymology and medicine
    • Khosla, C. (2000) Natural product biosynthesis: A new interface between enzymology and medicine J. Org. Chem. 65, 8127-8133
    • (2000) J. Org. Chem. , vol.65 , pp. 8127-8133
    • Khosla, C.1
  • 5
    • 0026559262 scopus 로고
    • Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea
    • Donadio, S. and Katz, L. (1992) Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea Gene 111, 51-60
    • (1992) Gene , vol.111 , pp. 51-60
    • Donadio, S.1    Katz, L.2
  • 6
    • 0026415106 scopus 로고
    • Modular organization of genes required for complex polyketide biosynthesis
    • Donadio, S., Staver, M. J, Mcalpine, J. B, Swanson, S. J, and Katz, L. (1991) Modular organization of genes required for complex polyketide biosynthesis Science 252, 675-679
    • (1991) Science , vol.252 , pp. 675-679
    • Donadio, S.1    Staver, M.J.2    McAlpine, J.B.3    Swanson, S.J.4    Katz, L.5
  • 7
    • 34848843433 scopus 로고    scopus 로고
    • The type i fatty acid and polyketide synthases: A tale of two megasynthases
    • Smith, S. and Tsai, S.-C. (2007) The type I fatty acid and polyketide synthases: a tale of two megasynthases Nat. Prod. Rep. 24, 1041-1072
    • (2007) Nat. Prod. Rep. , vol.24 , pp. 1041-1072
    • Smith, S.1    Tsai, S.-C.2
  • 8
    • 0028557012 scopus 로고
    • The animal fatty acid synthase: One gene, one polypeptide, seven enzymes
    • Smith, S. (1994) The animal fatty acid synthase: one gene, one polypeptide, seven enzymes FASEB J. 8, 1248-1259
    • (1994) FASEB J. , vol.8 , pp. 1248-1259
    • Smith, S.1
  • 9
    • 0024315871 scopus 로고
    • Fatty acid synthase, a proficient multifunctional enzyme
    • Wakil, S. J. (1989) Fatty acid synthase, a proficient multifunctional enzyme Biochemistry 28, 4523-4530
    • (1989) Biochemistry , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 11
    • 33644687879 scopus 로고    scopus 로고
    • Architectural options for a fatty acid synthase
    • Smith, S. (2006) Architectural options for a fatty acid synthase Science 311, 1251-1252
    • (2006) Science , vol.311 , pp. 1251-1252
    • Smith, S.1
  • 12
    • 33644697200 scopus 로고    scopus 로고
    • Architecture of mammalian fatty acid synthase at 4.5 Å resolution
    • Maier, T., Jenni, S., and Ban, N. (2006) Architecture of mammalian fatty acid synthase at 4.5 Å resolution Science 311, 1258-1262
    • (2006) Science , vol.311 , pp. 1258-1262
    • Maier, T.1    Jenni, S.2    Ban, N.3
  • 14
    • 0141736926 scopus 로고    scopus 로고
    • Strategies for combinatorial biosynthesis with modular polyketide synthases
    • Donadio, S. and Sosio, M. (2003) Strategies for combinatorial biosynthesis with modular polyketide synthases Comb. Chem. High Throughput Screening 6, 489-500
    • (2003) Comb. Chem. High Throughput Screening , vol.6 , pp. 489-500
    • Donadio, S.1    Sosio, M.2
  • 15
    • 0036523418 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of antibiotics: Challenges and opportunities
    • Walsh, C. T. (2002) Combinatorial biosynthesis of antibiotics: Challenges and opportunities ChemBioChem. 3, 124-134
    • (2002) ChemBioChem. , vol.3 , pp. 124-134
    • Walsh, C.T.1
  • 16
    • 0035313411 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of polyketides and nonribosomal peptides
    • Staunton, J. and Wilkinson, B. (2001) Combinatorial biosynthesis of polyketides and nonribosomal peptides Curr. Opin. Chem. Biol. 5, 159-164
    • (2001) Curr. Opin. Chem. Biol. , vol.5 , pp. 159-164
    • Staunton, J.1    Wilkinson, B.2
  • 17
    • 0032475992 scopus 로고    scopus 로고
    • Harnessing the biosynthetic code: Combinations, permutations, and mutations
    • Cane, D. E., Walsh, C. T., and Khosla, C. (1998) Harnessing the biosynthetic code: combinations, permutations, and mutations Science 282, 63-68
    • (1998) Science , vol.282 , pp. 63-68
    • Cane, D.E.1    Walsh, C.T.2    Khosla, C.3
  • 18
    • 0033515090 scopus 로고    scopus 로고
    • Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel ″unnatural″ natural products
    • McDaniel, R., Thamchaipenet, A., Gustafsson, C., Fu, H., Betlach, M., and Ashley, G. (1996) Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel ″unnatural″ natural products Proc. Natl. Acad. Sci. U.S.A. 96, 1846-1851
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 1846-1851
    • McDaniel, R.1    Thamchaipenet, A.2    Gustafsson, C.3    Fu, H.4    Betlach, M.5    Ashley, G.6
  • 19
    • 0032738419 scopus 로고    scopus 로고
    • A multiplasmid approach to preparing large libraries of polyketides
    • Xue, Q., Ashley, G., Hutchinson, C., and Santi, D. (1999) A multiplasmid approach to preparing large libraries of polyketides Proc. Natl. Acad. Sci. U.S.A. 96, 11740-11745
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 11740-11745
    • Xue, Q.1    Ashley, G.2    Hutchinson, C.3    Santi, D.4
  • 20
    • 0030763125 scopus 로고    scopus 로고
    • Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives
    • Ruan, X., Pereda, A., and Stassi, D. L. 1997, Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives J. Bacteriol. 179, 6416-25
    • (1997) J. Bacteriol. , vol.179 , pp. 6416-6425
    • Ruan, X.1    Pereda, A.2    Stassi, D.L.3
  • 21
    • 78650660868 scopus 로고    scopus 로고
    • Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase
    • Kapur, S., Chen, A. Y., Cane, D. E., and Khosla, C. (2010) Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase Proc. Natl. Acad. Sci. U.S.A. 107, 22066-22071
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 22066-22071
    • Kapur, S.1    Chen, A.Y.2    Cane, D.E.3    Khosla, C.4
  • 22
    • 77955446661 scopus 로고    scopus 로고
    • Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases
    • Tran, L., Broadhurst, W. R., Tosin, M., Cavalli, A., and Weissman, K. J. (2010) Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases Chem. Biol. 17, 705-716
    • (2010) Chem. Biol. , vol.17 , pp. 705-716
    • Tran, L.1    Broadhurst, W.R.2    Tosin, M.3    Cavalli, A.4    Weissman, K.J.5
  • 23
    • 33646561232 scopus 로고    scopus 로고
    • Activating hybrid modular interfaces in synthetic polyketide synthases by cassette replacement of ketosynthase domains
    • Chandran, S. S., Menzella, H. G., Carney, J. R., and Santi, D. V. (2006) Activating hybrid modular interfaces in synthetic polyketide synthases by cassette replacement of ketosynthase domains Chem. Biol. 13, 469-474
    • (2006) Chem. Biol. , vol.13 , pp. 469-474
    • Chandran, S.S.1    Menzella, H.G.2    Carney, J.R.3    Santi, D.V.4
  • 24
    • 0025788488 scopus 로고
    • Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. I. Production, isolation, chemical properties and biological activities
    • Naruse, N., Tenmkyo, O., Kawano, K., Tomita, K., Ohgusa, N., Miyaki, T., Konishi, M., and Oki, T. (1991) Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. I. Production, isolation, chemical properties and biological activities J. Antibiot. 44, 733-740
    • (1991) J. Antibiot. , vol.44 , pp. 733-740
    • Naruse, N.1    Tenmkyo, O.2    Kawano, K.3    Tomita, K.4    Ohgusa, N.5    Miyaki, T.6    Konishi, M.7    Oki, T.8
  • 25
    • 0025887029 scopus 로고
    • Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. II. Structure determination
    • Naruse, N., Tsuno, T., Sawada, Y., Konishi, M., and Oki, T. (1991) Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. II. Structure determination J. Antibiot. 44, 741-755
    • (1991) J. Antibiot. , vol.44 , pp. 741-755
    • Naruse, N.1    Tsuno, T.2    Sawada, Y.3    Konishi, M.4    Oki, T.5
  • 26
    • 0025823878 scopus 로고
    • Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. III. the stereochemistry and absolute configuration of fluvirucin A1
    • Naruse, N., Konishi, M., and Oki, T. (1991) Fluvirucins A1, A2, B1, B2, B3, B4 and B5, new antibiotics active against influenza A virus. III. The stereochemistry and absolute configuration of fluvirucin A1 J. Antibiot. 44, 756-761
    • (1991) J. Antibiot. , vol.44 , pp. 756-761
    • Naruse, N.1    Konishi, M.2    Oki, T.3
  • 27
    • 0037423499 scopus 로고    scopus 로고
    • Enzymology of acyl chain macrocyclization in natural product biosynthesis
    • Kohli, R. M. and Walsh, C. T. (2003) Enzymology of acyl chain macrocyclization in natural product biosynthesis Chem. Commun. 3, 297-307
    • (2003) Chem. Commun. , vol.3 , pp. 297-307
    • Kohli, R.M.1    Walsh, C.T.2
  • 28
    • 33645364955 scopus 로고    scopus 로고
    • Macrolactonizations in the total synthesis of natural products
    • Parenty, A., Moreau, X., and Campagne, J. M. (2006) Macrolactonizations in the total synthesis of natural products Chem. Rev. 106, 911-939
    • (2006) Chem. Rev. , vol.106 , pp. 911-939
    • Parenty, A.1    Moreau, X.2    Campagne, J.M.3
  • 29
    • 35348843479 scopus 로고    scopus 로고
    • Synthesis of lipophilic 2-oxoamides based on γ-aminobutyric and δ-aminovaleric analogues and their activity against phospholipase A2
    • Moutevelis-Minakakis, P., Neokosmidi, A., Filippakou, M., Stephens, D., Dennis, E. A., and Kokotos, G. (2007) Synthesis of lipophilic 2-oxoamides based on γ-aminobutyric and δ-aminovaleric analogues and their activity against phospholipase A2 J. Pept. Sci. 13, 634-641
    • (2007) J. Pept. Sci. , vol.13 , pp. 634-641
    • Moutevelis-Minakakis, P.1    Neokosmidi, A.2    Filippakou, M.3    Stephens, D.4    Dennis, E.A.5    Kokotos, G.6
  • 30
    • 1142281949 scopus 로고    scopus 로고
    • Cloning, Sequencing, and Functional Analysis of the Biosynthetic Gene Cluster of Macrolactam Antibiotic Vicenistatin in Streptomyces halstedii
    • Ogasawara, Y., Katayama, K., Minami, A., Otsuka, M., Eguchi, T., and Kakinuma, K. (2004) Cloning, Sequencing, and Functional Analysis of the Biosynthetic Gene Cluster of Macrolactam Antibiotic Vicenistatin in Streptomyces halstedii Chem. Biol. 11, 79-86
    • (2004) Chem. Biol. , vol.11 , pp. 79-86
    • Ogasawara, Y.1    Katayama, K.2    Minami, A.3    Otsuka, M.4    Eguchi, T.5    Kakinuma, K.6
  • 31
    • 0041620248 scopus 로고    scopus 로고
    • SEARCHPKS: A program for detection and analysis of polyketide synthase domains
    • Yadav, G., Gokhale, R. S., and Mohanty, D. (2003) SEARCHPKS: a program for detection and analysis of polyketide synthase domains Nucleic Acids Res. 31, 3654-3658
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3654-3658
    • Yadav, G.1    Gokhale, R.S.2    Mohanty, D.3
  • 32
    • 34547945950 scopus 로고    scopus 로고
    • A tylosin ketoreductase reveals how chirality is determined in polyketides
    • Keatinge-Clay, A. T. (2007) A tylosin ketoreductase reveals how chirality is determined in polyketides Chem. Biol. 14, 898-908
    • (2007) Chem. Biol. , vol.14 , pp. 898-908
    • Keatinge-Clay, A.T.1
  • 33
    • 72449196714 scopus 로고    scopus 로고
    • Biosynthetic studies of aziridine formation in azicemicins
    • Ogasawara, Y. and Liu, H.-W. (2009) Biosynthetic studies of aziridine formation in azicemicins J. Am. Chem. Soc. 131, 18066-18068
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 18066-18068
    • Ogasawara, Y.1    Liu, H.-W.2
  • 34
    • 0024251373 scopus 로고    scopus 로고
    • Evolution of an active-site codon in serine proteases
    • Irwin, D. M. (1998) Evolution of an active-site codon in serine proteases Nature 336, 429-430
    • (1998) Nature , vol.336 , pp. 429-430
    • Irwin, D.M.1
  • 35
    • 0026661647 scopus 로고
    • Utilization of an active serine 101-cysteine mutant to demonstrate the proximity of the catalytic serine 101 and histidine 237 residues in thioesterase II
    • Witzowski, A., Naggert, J., Witkowska, H. E., Randhawa, Z. I., and Smith, S. (1992) Utilization of an active serine 101-cysteine mutant to demonstrate the proximity of the catalytic serine 101 and histidine 237 residues in thioesterase II J. Biol. Chem. 267, 18488-18492
    • (1992) J. Biol. Chem. , vol.267 , pp. 18488-18492
    • Witzowski, A.1    Naggert, J.2    Witkowska, H.E.3    Randhawa, Z.I.4    Smith, S.5
  • 36
    • 0028040231 scopus 로고
    • Reengineering the specificity of a serine active-site enzyme. Two active-site mutations convert a hydrolase to a transferase
    • Witzowski, A., Witkowska, H. E., and Smith, S. (1994) Reengineering the specificity of a serine active-site enzyme. Two active-site mutations convert a hydrolase to a transferase J. Biol. Chem. 269, 379-383
    • (1994) J. Biol. Chem. , vol.269 , pp. 379-383
    • Witzowski, A.1    Witkowska, H.E.2    Smith, S.3
  • 37
    • 0035934175 scopus 로고    scopus 로고
    • The enhancement of PCR amplification by low molecular-weight sulfones
    • Chakrabarti, R. and Schutt, C. E. (2001) The enhancement of PCR amplification by low molecular-weight sulfones Gene 274, 293-298
    • (2001) Gene , vol.274 , pp. 293-298
    • Chakrabarti, R.1    Schutt, C.E.2
  • 38
    • 79851505835 scopus 로고    scopus 로고
    • Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues
    • SangJoon, Mo 2011, Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues J. Am. Chem. Soc. 133, 976-985
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 976-985
    • Sangjoon, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.