Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR

Nature Immunology

Volumn 14, Issue 12, 2013, Pages 1219-1228

  Ivanov, Stanimir S ^a   Roy, Craig R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CALNEXIN; CIS ACTING ELEMENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PATTERN RECOGNITION RECEPTOR; PROTEIN S6; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; BACTERIAL VIABILITY; BACTERIUM DETECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; INNATE IMMUNITY; INTRACELLULAR BACTERIUM; LEGIONELLA PNEUMOPHILA; MACROPHAGE; MOUSE; MYRISTYLATION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TRANSLATION INITIATION; UBIQUITINATION; UNTRANSLATED REGION;

ANIMALS; BASE SEQUENCE; CELL LINE; CELLS, CULTURED; CYTOKINES; EUKARYOTIC INITIATION FACTOR-4E; GENE EXPRESSION; HOST-PATHOGEN INTERACTIONS; IMMUNOBLOTTING; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UBIQUITINATION;

EID: 84887917428     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2740     Document Type: Article

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