Stereochemistry of the tadalafil diastereoisomers: A critical assessment of vibrational circular dichroism, electronic circular dichroism, and optical rotatory dispersion

Journal of Medicinal Chemistry

Volumn 56, Issue 21, 2013, Pages 8903-8914

  Qiu, Shi ^a   De Gussem, Ewoud ^a,b   Abbaspour Tehrani, Kourosch ^a   Sergeyev, Sergey ^a   Bultinck, Patrick ^a,b   Herrebout, Wouter ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

TADALAFIL;

ARTICLE; ATOM; CARBON NUCLEAR MAGNETIC RESONANCE; CIRCULAR DICHROISM; DIASTEREOISOMER; DRUG CONFORMATION; ELECTRONIC CIRCULAR DICHROISM; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; INFRARED SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; OPTICAL ROTATORY DISPERSION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STEREOISOMERISM; VIBRATIONAL CIRCULAR DICHROISM; X RAY CRYSTALLOGRAPHY;

CARBOLINES; CIRCULAR DICHROISM; MOLECULAR CONFORMATION; OPTICAL ROTATORY DISPERSION; QUANTUM THEORY; STEREOISOMERISM; VIBRATION;

EID: 84887876246     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401407w     Document Type: Article

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