Extracellular polysaccharide from Bacillus sp. strain LBP32 prevents LPS-induced inflammation in RAW 264.7 macrophages by inhibiting NF-κB and MAPKs activation and ROS production

International Immunopharmacology

Volumn 18, Issue 1, 2014, Pages 12-19

  Diao, Ying ^a   Xin, Yinqiang ^a   Zhou, Yi ^a   Li, Na ^a   Pan, Xiaolong ^a   Qi, Shimei ^a   Qi, Zhilin ^a   Xu, Yimiao ^a   Luo, Lan ^b,d   Wan, Honggui ^c,d   Lan, Lei ^a,d   Yin, Zhimin ^a,d  

^a NANJING NORMAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c NANJING TECH UNIVERSITY   (China)

^d Jiangsu Life Sciences and Technology Innovation Park ^*  (China)

Author keywords

ASK1; EPS; Inflammation; MAPKs; NF B; ROS

Indexed keywords

ANTIINFLAMMATORY AGENT; BACTERIUM LIPOPOLYSACCHARIDE; DEXAMETHASONE; EXTRACELLULAR POLYSACCHARIDE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACILLUS; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IN VIVO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK; WESTERN BLOTTING;

ASK1; EPS; INFLAMMATION; MAPKS; NF-ΚB; ROS;

ANIMALS; BACILLUS; CELL LINE; DOWN-REGULATION; ENDOTOXEMIA; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRAM-POSITIVE BACTERIAL INFECTIONS; IMMUNOSUPPRESSION; INFLAMMATION MEDIATORS; MACROPHAGES; MICE; NF-KAPPA B; POLYSACCHARIDES, BACTERIAL; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; VIRULENCE FACTORS;

EID: 84887862192     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.10.021     Document Type: Article

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