Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 3, 2011, Pages 331-341

  Bava, Smitha V ^a   Sreekanth, Chanickal N ^a   Thulasidasan, Arun Kumar T ^a   Anto, Nikhil P ^a   Cheriyan, Vino T ^a   Puliyappadamba, Vineshkumar T ^a   Menon, Sajna G ^a   Ravichandran, Santhosh D ^a   Anto, Ruby John ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

Akt; Curcumin; MAPKs; NF B; Paclitaxel; Synergism

Indexed keywords

CURCUMIN; CYCLIN D1; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PACLITAXEL; PROTEIN BCL 2; PROTEIN KINASE B; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; UPREGULATION;

CELL CYCLE; CELL SURVIVAL; CURCUMIN; CYCLIN D1; CYCLOOXYGENASE 2; DOWN-REGULATION; DRUG SYNERGISM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NF-KAPPA B; PACLITAXEL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 79751524878     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.09.011     Document Type: Article

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