Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats

Neuropharmacology

Volumn 77, Issue , 2014, Pages 398-405

  Song, Rui ^a,b   Bi, Guo Hua ^a   Zhang, Hai Ying ^a   Yang, Ri Fang ^b   Gardner, Eliot L ^a   Li, Jin ^b   Xi, Zheng Xiong ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Cocaine; D3 receptors; Dopamine; Reinstatement; Reward; YQA14

Indexed keywords

COCAINE; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DRUGS USED IN THE TREATMENT OF ADDICTION; UNCLASSIFIED DRUG; YQA 14;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DEPTH STIMULATION; COCAINE DEPENDENCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG HALF LIFE; DRUG SEEKING BEHAVIOR; DRUG SELF ADMINISTRATION; DRUG SENSITIZATION; ELECTROSTIMULATION; FACILITATION; MALE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RELAPSE;

COCAINE; D3 RECEPTORS; DOPAMINE; REINSTATEMENT; REWARD; YQA14;

ANIMALS; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; BENZOXAZOLES; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-SEEKING BEHAVIOR; ELECTRIC STIMULATION; MALE; PIPERAZINES; RATS; RATS, LONG-EVANS; RECEPTORS, DOPAMINE D3; RECURRENCE; REWARD;

EID: 84887841058     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.10.010     Document Type: Article

References (53)

1. B.J. Aragona, J.J. Day, M.F. Roitman, N.A. Cleaveland, R.M. Wightman, and R.M. Carelli Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats Eur. J. Neurosci. 30 2009 1889 1899
2. 2 receptor mRNA Brain Res. 564 1991 203 219
3. M.E. Bouton Context, ambiguity, and unlearning: sources of relapse after behavioral extinction Biol. Psychiatry 52 2002 976 986 (Pubitemid 35356355)
4. K.L. Conrad, K. Ford, M. Marinelli, and M.E. Wolf Dopamine receptor expression and distribution dynamically change in the rat nucleus accumbens after withdrawal from cocaine self-administration Neuroscience 169 2010 182 194
5. J.J. Day, M.F. Roitman, R.M. Wightman, and R.M. Carelli Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens Nat. Neurosci. 10 2007 1020 1028 (Pubitemid 47185195)
6. G. Di Chiara, and A. Imperato Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats Proc. Natl. Acad. Sci. U. S. A. 85 1988 5274 5278
7. 3 receptor in the rat brain Neuroscience 65 1995 731 745
8. K. Gál, and I. Gyertyán Dopamine D3 as well as D2 receptor ligands attenuate the cue-induced cocaine-seeking in a relapse model in rats Drug Alcohol Depend. 81 2006 63 70 (Pubitemid 41682480)
9. E.L. Gardner Brain reward mechanisms J.H. Lowinson, P. Ruiz, R.B. Millman, J.G. Langrod, Substance Abuse: a Comprehensive Textbook fourth ed. 2005 Lippincott Williams & Wilkins Philadelphia 48 97
10. P. Gorwood, Y. Le Strat, N. Ramoz, C. Dubertret, J.-M. Moalic, and M. Simonneau Genetics of dopamine receptors and drug addiction Hum. Genet. 131 2012 803 822
11. J.W. Grimm, L. Lu, T. Hayashi, B.T. Hope, T.-P. Su, and Y. Shaham Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving J. Neurosci. 23 2003 742 747 (Pubitemid 36206164)
12. P. Grundt, E.E. Carlson, J. Cao, C.J. Bennett, E. McElveen, M. Taylor, R.R. Luedtke, and A.H. Newman Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor J. Med. Chem. 48 2005 839 848 (Pubitemid 40209106)
13. 3 receptors in drug addiction: a review of pharmacological evidence Brain Res. Rev. 49 2005 77 105 (Pubitemid 40800164)
14. 3 receptor antagonists as pharmacotherapeutics for addictions and related disorders Ann. N. Y. Acad. Sci. 1187 2010 4 34
15. 3 receptor antagonist, inhibits the effects of methamphetamine in rats J. Psychopharmacol. 25 2011 263 273
16. R. Ito, J.W. Dalley, S.R. Howes, T.W. Robbins, and B.J. Everitt Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats J. Neurosci. 20 2000 7489 7495
17. P.W. Kalivas, and K. McFarland Brain circuitry and the reinstatement of cocaine-seeking behavior Psychopharmacology 168 2003 44 56 (Pubitemid 36851162)
18. L. Lu, J.W. Grimm, B.T. Hope, and Y. Shaham Incubation of cocaine craving after withdrawal: a review of preclinical data Neuropharmacology 47 Suppl. 1 2004 214 226 (Pubitemid 39298266)
19. C. Lüscher, and R.C. Malenka Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling Neuron 69 2011 650 663
20. 3 receptor antagonist J. Med. Chem. 46 2003 4952 4964 (Pubitemid 37355955)
21. 3 receptor binding in rats receiving a cocaine challenge at various time points after cocaine self-administration: implications for cocaine-seeking behavior Neuropsychopharmacology 29 2004 1479 1487 (Pubitemid 38982240)
22. B.Á. Nic Dhonnchadha, and K.M. Kantak Cognitive enhancers for facilitating drug cue extinction: insights from animal models Pharmacol. Biochem. Behav. 99 2011 229 244
23. 3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions Int. J. Neuropsychopharmacol. 9 2006 585 602 (Pubitemid 44607211)
24. G. Paxinos, and C. Watson The Rat Brain in Stereotaxic Coordinates 4th ed. 1998 Academic Press San Diego
25. 3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats Neuropharmacology 56 2009 752 760
26. 3 receptor agonist Nature 400 1999 371 375 (Pubitemid 29344203)
27. G.J. Quirk, and D. Mueller Neural mechanisms of extinction learning and retrieval Neuropsychopharmacology 33 2008 56 72 (Pubitemid 350191313)
28. 3 receptor antagonist, SB-277011-A J. Pharmacol. Exp. Ther. 294 2000 1154 1165 (Pubitemid 30666872)
29. Y. Shaham, and J. Stewart Exposure to mild stress enhances the reinforcing efficacy of intravenous heroin self-administration in rats Psychopharmacology 114 1994 523 527 (Pubitemid 24153505)
30. U. Shalev, J.W. Grimm, and Y. Shaham Neurobiology of relapse to heroin and cocaine seeking: a review Pharmacol. Rev. 54 2002 1 42 (Pubitemid 34208828)
31. U. Shalev, D. Highfield, J. Yap, and Y. Shaham Stress and relapse to drug seeking in rats: studies on the generality of the effect Psychopharmacology 150 2000 337 346 (Pubitemid 30447854)
32. P. Sokoloff, B. Giros, M.-P. Martres, M. Andrieux, R. Besançon, C. Pilon, M.-L. Bouthenet, E. Souil, and J.-C. Schwartz Localization and function of the D3 dopamine receptor Arzneimittelforschung 42 2A 1992 224 230
33. 3 receptor-knockout mice Addict Biol. 17 2012 259 273
34. 3 receptors Proc. Natl. Acad. Sci. U. S. A. 109 2012 17675 17680
35. 3 receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice Neuropharmacology 72 2013 82 87
36. 3 dopamine receptors in the brain reward circuits of human cocaine fatalities J. Neurosci. 16 1996 6100 6106 (Pubitemid 26313985)
37. L. Stein, and O.S. Ray Brain stimulation reward "thresholds" self-determined in rat Psychopharmacologia (Berl) 1 1960 251 256
38. J. Stewart Pathways to relapse: the neurobiology of drug- and stress-induced relapse to drug-taking J. Psychiatry Neurosci. 25 2000 125 136 (Pubitemid 30233550)
39. L.W. Swanson The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat Brain Res. Bull 9 1982 321 353 (Pubitemid 13225278)
40. M.M. Torregrossa, and P.W. Kalivas Microdialysis and the neurochemistry of addiction Pharmacol. Biochem. Behav. 90 2008 261 272 (Pubitemid 351787343)
41. N.D. Volkow, G.-J. Wang, F. Telang, J.S. Fowler, J. Logan, A.-R. Childress, M. Jayne, Y. Ma, and C. Wong Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction J. Neurosci. 26 2006 6583 6588 (Pubitemid 44318339)
42. N.D. Volkow, G.-J. Wang, F. Telang, J.S. Fowler, J. Logan, A.-R. Childress, M. Jayne, Y. Ma, and C. Wong Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues Neuroimage 39 2008 1266 1273
43. 3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats J. Neurosci. 22 2002 9595 9603 (Pubitemid 35356201)
44. R.A. Wise Neurobiology of addiction Curr. Opin. Neurobiol. 6 1996 243 251 (Pubitemid 26168484)
45. R.A. Wise, and E.L. Gardner Animal models of addiction D.S. Charney, E.J. Nestler, Neurobiology of Mental Illness second ed. 2004 Oxford University Press Oxford, England 683 697
46. 3 receptor antagonist, in animal models of drug addiction CNS Drug Rev. 13 2007 240 259 (Pubitemid 47052351)
47. 3 receptor antagonism by SB-277011A attenuates cocaine reinforcement as assessed by progressive-ratio and variable-cost&variable-payoff cocaine self administration in rats Eur. J. Neurosci. 21 2005 3427 3438 (Pubitemid 40961437)
48. Z.-X. Xi, M. Kiyatkin, X. Li, X.-Q. Peng, A. Wiggins, K. Spiller, J. Li, and E.L. Gardner N-acetyl-aspartatylglutamate (NAAG) attenuates cocaine-enhanced brain-stimulation reward and cocaine self-administration in rats Neuropharmacology 58 2010 304 313
49. 3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats Addict Biol. 18 2013 665 677
50. 3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats Neuropsychopharmacology 31 2006 1393 1405
51. Z.-X. Xi, K. Spiller, A.C. Pak, J. Gilbert, C. Dillon, X. Li, X.-Q. Peng, and E.L. Gardner Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats Neuropsychopharmacology 33 2008 1735 1745 (Pubitemid 351684714)
52. Y.-X. Xue, Y.-X. Luo, P. Wu, H.-S. Shi, L.-F. Xue, C. Chen, W.-L. Zhu, Z.-B. Ding, Y.-P. Bao, J. Shi, D.H. Epstein, Y. Shaham, and L. Lu A memory retrieval-extinction procedure to prevent drug craving and relapse Science 336 2012 241 245
53. 3 receptor antagonists Bioorg. Med. Chem. Lett. 8 1998 2715 2718 (Pubitemid 28496658)