The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats

Neuropharmacology

Volumn 56, Issue 4, 2009, Pages 752-760

  Peng, Xiao Qing ^a   Ashby Jr , Charles R ^b   Spiller, Krista ^a   Li, Xia ^a   Li, Jie ^a   Thomasson, Nitza ^c   Millan, Mark J ^d   Mocaër, Elisabeth ^c   Muńoz, Carmen ^c   Gardner, Eliot L ^a   Xi, Zheng Xiong ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b ST JOHN'S UNIVERSITY   (United States)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^d INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Brain reward; Cocaine; Dopamine; Reinstatement; S33138; Self administration

Indexed keywords

COCAINE; DOPAMINE 3 RECEPTOR BLOCKING AGENT; N [4 [2 (8 CYANO 1,3A,4,9B TETRAHYDRO[1]BENZOPYRANO[3,4 C]PYRROL 2(3H) YL)ETHYL]PHENYL]ACETAMIDE; PYRROLIDINE DERIVATIVE; S 33138; UNCLASSIFIED DRUG; ACETANILIDE DERIVATIVE; BENZOPYRAN DERIVATIVE; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE UPTAKE INHIBITOR; N (4 (2 (8 CYANO 1,3A,4,9B TETRAHYDRO(1)BENZOPYRANO(3,4 C)PYRROL 2(3H) YL)ETHYL)PHENYL)ACETAMIDE; N-(4-(2-(8-CYANO-1,3A,4,9B-TETRAHYDRO(1)BENZOPYRANO(3,4-C)PYRROL-2(3H)-YL)ETHYL)PHENYL)ACETAMIDE; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG RESPONSE; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RELAPSE; REWARD; ANIMAL; BODY EQUILIBRIUM; DRUG ANTAGONISM; DRUG SELF ADMINISTRATION; ELECTROSTIMULATION; INTRAVENOUS DRUG ADMINISTRATION; LONG EVANS RAT; MOTOR ACTIVITY; PSYCHOLOGICAL ASPECT; PSYCHOMOTOR PERFORMANCE; RECURRENT DISEASE; REINFORCEMENT; SELF STIMULATION;

ACETANILIDES; ANIMALS; BENZOPYRANS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXTINCTION, PSYCHOLOGICAL; INJECTIONS, INTRAVENOUS; MALE; MOTOR ACTIVITY; POSTURAL BALANCE; PSYCHOMOTOR PERFORMANCE; RATS; RATS, LONG-EVANS; RECEPTORS, DOPAMINE D3; RECURRENCE; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION; SELF STIMULATION; SUCROSE;

EID: 60149089294     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.12.007     Document Type: Article

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