Use of ex vivo and in vitro cultures of the human respiratory tract to study the tropism and host responses of highly pathogenic avian influenza A (H5N1) and other influenza viruses

Virus Research

Volumn 178, Issue 1, 2013, Pages 133-145

  Chan, Renee W Y ^a   Chan, Michael C W ^a   Nicholls, John M ^a   Malik Peiris, J S ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

H5N1 influenza virus; Host response; Human respiratory epithelial cell in vitro cultures; Human respiratory organ ex vivo cultures; Tissue tropism

Indexed keywords

GLYCAN; SIALIC ACID DERIVATIVE; VIRUS RECEPTOR;

APOPTOSIS; ARTICLE; ASTROCYTE; CELL DEATH; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONJUNCTIVA EPITHELIUM; DENDRITIC CELL; DIGESTIVE SYSTEM; ENDOTHELIUM CELL; EPITHELIUM CELL; EX VIVO STUDY; EXPERIMENTAL MODEL; FETUS; HUMAN; HUMAN CELL CULTURE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO CULTURE; INFLUENZA; INFLUENZA A (H5N1); INFLUENZA VIRUS; INFLUENZA VIRUS A H5N1; INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG PARENCHYMA; LYMPHOCYTE; MONOCYTE; NASOPHARYNX; NEUTROPHIL; NONHUMAN; PLACENTA; PRIMARY CELL CULTURE; PRIORITY JOURNAL; RESPIRATORY SYSTEM; VIRAL TROPISM; VIRUS ATTACHMENT; VIRUS CULTURE; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALIA; AVES; ORTHOMYXOVIRIDAE;

H5N1 INFLUENZA VIRUS; HOST RESPONSE; HUMAN RESPIRATORY EPITHELIAL CELL IN VITRO CULTURES; HUMAN RESPIRATORY ORGAN EX VIVO CULTURES; TISSUE TROPISM;

ANIMALS; CELL CULTURE TECHNIQUES; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; ORTHOMYXOVIRIDAE; RESPIRATORY SYSTEM; VIRAL TROPISM;

EID: 84887624543     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2013.03.003     Document Type: Article

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