H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades

Journal of Infectious Diseases

Volumn 204, Issue 12, 2011, Pages 1866-1878

  Hui, Kenrie P Y ^a   Lee, Suki M Y ^a   Cheung, Chung Yan ^a   Mao, Huawei ^a   Lai, Angela K W ^a   Chan, Renee W Y ^a   Chan, Michael C W ^a   Tu, Wenwei ^a   Guan, Yi ^a   Lau, Yu Lung ^a   Peiris, J S M ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HKU PASTEUR RESEARCH CENTRE   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 29; JANUS KINASE; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; HUMAN; HUMAN CELL; INFLUENZA A (H1N1); INFLUENZA A (H5N1); INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; LUNG ALVEOLUS EPITHELIUM; MACROPHAGE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; CYTOKINES; DEAD-BOX RNA HELICASES; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; INTERFERON REGULATORY FACTOR-3; JANUS KINASES; MACROPHAGES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PARACRINE COMMUNICATION; PULMONARY ALVEOLI; RECEPTOR, INTERFERON ALPHA-BETA; RNA, SMALL INTERFERING; RNA, VIRAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; UP-REGULATION;

EID: 81055143878     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir665     Document Type: Article

References (26)

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