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Volumn 8, Issue , 2011, Pages 457-479

Thermosensitive Polymers for Controlled Delivery of Hormones

Author keywords

Atomic Transfer Radical Polymerization; Lower Critical Solution Temperature; Matrix Assist Laser Desorption Ionization; Poly Lactic Acid

Indexed keywords


EID: 84887608746     PISSN: 18682006     EISSN: 18682014     Source Type: Book Series    
DOI: 10.1007/8415_2011_65     Document Type: Chapter
Times cited : (3)

References (81)
  • 2
    • 0028413537 scopus 로고
    • Micellization of Poly(Ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) triblock copolymers in aqueous solutions: Thermodynamics of copolymer association
    • Alexandridis, P., Holzwarth, J.F., Hatton, T.A.: Micellization of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) triblock copolymers in aqueous solutions: thermodynamics of copolymer association. Macromolecules 27(9), 2414–2425 (1994)
    • (1994) Macromolecules , vol.27 , Issue.9 , pp. 2414-2425
    • Alexandridis, P.1    Holzwarth, J.F.2    Hatton, T.A.3
  • 3
    • 34848910216 scopus 로고    scopus 로고
    • Smart polymer based delivery systems for peptides and proteins
    • Al-Tahami, K., Singh, J.: Smart polymer based delivery systems for peptides and proteins. Recent Pat. Drug Deliv. Formul. 1(1), 65–71 (2007)
    • (2007) Recent Pat. Drug Deliv. Formul. , vol.1 , Issue.1 , pp. 65-71
    • Al-Tahami, K.1    Singh, J.2
  • 4
    • 0033016761 scopus 로고    scopus 로고
    • Absorption of insulin from pluronic F-127 gels following subcutaneous administration in rats
    • Barichello, J.M., Morishita, M., Takayama, K., Nagai, T.: Absorption of insulin from pluronic F-127 gels following subcutaneous administration in rats. Int. J. Pharm. 184(2), 189–198 (1999)
    • (1999) Int. J. Pharm. , vol.184 , Issue.2 , pp. 189-198
    • Barichello, J.M.1    Morishita, M.2    Takayama, K.3    Nagai, T.4
  • 5
    • 28244441173 scopus 로고    scopus 로고
    • Pyrene absorption can be a convenient method for probing critical micellar concentration (Cmc) and indexing micellar polarity
    • Basu Ray, G., Chakraborty, I., Moulik, S.P.: Pyrene absorption can be a convenient method for probing critical micellar concentration (cmc) and indexing micellar polarity. J. Colloid Interface Sci. 294(1), 248–254 (2006)
    • (2006) J. Colloid Interface Sci. , vol.294 , Issue.1 , pp. 248-254
    • Basu Ray, G.1    Chakraborty, I.2    Moulik, S.P.3
  • 6
    • 0036158668 scopus 로고    scopus 로고
    • Synthesis and characterization of triblock copolymers of methoxy poly(Ethylene glycol) and poly(propylene fumarate)
    • Behravesh, E., Shung, A.K., Jo, S., Mikos, A.G.: Synthesis and characterization of triblock copolymers of methoxy poly(ethylene glycol) and poly(propylene fumarate). Biomacromolecules 3(1), 153–158 (2002)
    • (2002) Biomacromolecules , vol.3 , Issue.1 , pp. 153-158
    • Behravesh, E.1    Shung, A.K.2    Jo, S.3    Mikos, A.G.4
  • 7
    • 0031723469 scopus 로고    scopus 로고
    • Liposomes dispersed within a thermosensitive gel: A new dosage form for ocular delivery of oligonucleotides
    • Bochot, A., Fattal, E., Gulik, A., Couarraze, G., Couvreur, P.: Liposomes dispersed within a thermosensitive gel: a new dosage form for ocular delivery of oligonucleotides. Pharm. Res. 15(9), 1364–1369 (1998)
    • (1998) Pharm. Res. , vol.15 , Issue.9 , pp. 1364-1369
    • Bochot, A.1    Fattal, E.2    Gulik, A.3    Couarraze, G.4    Couvreur, P.5
  • 8
    • 73949117709 scopus 로고    scopus 로고
    • Influence of amide versus ester linkages on the properties of eight-armed PEG–PLA star block copolymer hydrogels
    • Buwalda, S.J., Dijkstra, P.J., Calucci, L., Forte, C., Feijen, J.: Influence of amide versus ester linkages on the properties of eight-armed PEG–PLA star block copolymer hydrogels. Biomacromolecules 11(1), 224–232 (2010)
    • (2010) Biomacromolecules , vol.11 , Issue.1 , pp. 224-232
    • Buwalda, S.J.1    Dijkstra, P.J.2    Calucci, L.3    Forte, C.4    Feijen, J.5
  • 9
    • 0027228385 scopus 로고
    • Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone
    • Charman, S.A., Mason, K.L., Charman, W.N.: Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone. Pharm. Res. 10(7), 954–962 (1993)
    • (1993) Pharm. Res. , vol.10 , Issue.7 , pp. 954-962
    • Charman, S.A.1    Mason, K.L.2    Charman, W.N.3
  • 10
    • 0019760856 scopus 로고
    • Comparison of lidocaine release from Pluronic F-127 gels and other formulations
    • Chen-CHow, P., Frank, S.G.: Comparison of lidocaine release from Pluronic F-127 gels and other formulations. Acta Pharm. Suec 18(4), 239–244 (1981)
    • (1981) Acta Pharm. Suec , vol.18 , Issue.4 , pp. 239-244
    • Chen-Chow, P.1    Frank, S.G.2
  • 11
    • 77955118299 scopus 로고    scopus 로고
    • In vivo absorption of steroidal hormones from smart polymer based delivery systems
    • Chen, S., Pederson, D., Oak, M., Singh, J.: In vivo absorption of steroidal hormones from smart polymer based delivery systems. J. Pharm. Sci. 99(8), 3381–3388 (2010)
    • (2010) J. Pharm. Sci. , vol.99 , Issue.8 , pp. 3381-3388
    • Chen, S.1    Pederson, D.2    Oak, M.3    Singh, J.4
  • 12
    • 11144341959 scopus 로고    scopus 로고
    • Triblock copolymers: Synthesis, characterization, and delivery of a model protein
    • Chen, S., Pieper, R., Webster, D.C., Singh, J.: Triblock copolymers: synthesis, characterization, and delivery of a model protein. Int. J. Pharm. 288(2), 207–218 (2005)
    • (2005) Int. J. Pharm. , vol.288 , Issue.2 , pp. 207-218
    • Chen, S.1    Pieper, R.2    Webster, D.C.3    Singh, J.4
  • 13
    • 17644380246 scopus 로고    scopus 로고
    • Controlled delivery of testosterone from smart polymer solution based systems: In vitro evaluation
    • Chen, S., Singh, J.: Controlled delivery of testosterone from smart polymer solution based systems: in vitro evaluation. Int. J. Pharm. 295(1–2), 183–190 (2005)
    • (2005) Int. J. Pharm. , vol.295 , Issue.1-2 , pp. 183-190
    • Chen, S.1    Singh, J.2
  • 14
    • 18744398737 scopus 로고    scopus 로고
    • In vitro release of levonorgestrel from phase sensitive and thermosensitive smart polymer delivery systems
    • Chen, S., Singh, J.: In vitro release of levonorgestrel from phase sensitive and thermosensitive smart polymer delivery systems. Pharm. Dev. Technol. 10(2), 319–325 (2005)
    • (2005) Pharm. Dev. Technol. , vol.10 , Issue.2 , pp. 319-325
    • Chen, S.1    Singh, J.2
  • 15
    • 39649106936 scopus 로고    scopus 로고
    • Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation
    • Chen, S., Singh, J.: Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation. Int. J. Pharm. 352(1–2), 58–65 (2008)
    • (2008) Int. J. Pharm. , vol.352 , Issue.1-2 , pp. 58-65
    • Chen, S.1    Singh, J.2
  • 16
    • 1542358689 scopus 로고    scopus 로고
    • Poly(D, L-lactide-ran-epsilon-caprolactone)-poly(ethylene glycol)-poly(D,L-lactide-ran-epsilon-caprolactone) as parenteral drug-delivery systems
    • Cho, H., Chung, D., Jeongho, A.: Poly(D, L-lactide-ran-epsilon-caprolactone)-poly(ethylene glycol)-poly(D,L-lactide-ran-epsilon-caprolactone) as parenteral drug-delivery systems. Biomaterials 25(17), 3733–3742 (2004)
    • (2004) Biomaterials , vol.25 , Issue.17 , pp. 3733-3742
    • Cho, H.1    Chung, D.2    Jeongho, A.3
  • 17
    • 79953005259 scopus 로고    scopus 로고
    • Injectable delivery system of 2-methoxyestradiol for breast cancer therapy using biodegradable thermosensitive poly(Organophosphazene) hydrogel
    • Cho, J.-K., Hong, K.-Y., Park, J.W., Yang, H., Song, S.-C.: Injectable delivery system of 2-methoxyestradiol for breast cancer therapy using biodegradable thermosensitive poly(organophosphazene) hydrogel. J. Drug Target (2010) (doi:10.3109/1061186X.2010. 499461)
    • (2010) J. Drug Target
    • Cho, J.-K.1    Hong, K.-Y.2    Park, J.W.3    Yang, H.4    Song, S.-C.5
  • 18
    • 3542994531 scopus 로고    scopus 로고
    • Control of blood glucose by novel GLP-1 delivery using biodegradable triblock copolymer of PLGA–PEG–PLGA in type 2 diabetic rats
    • Choi, S., Baudys, M., Kim, S.W.: Control of blood glucose by novel GLP-1 delivery using biodegradable triblock copolymer of PLGA–PEG–PLGA in type 2 diabetic rats. Pharm. Res. 21(5), 827–831 (2004)
    • (2004) Pharm. Res. , vol.21 , Issue.5 , pp. 827-831
    • Choi, S.1    Baudys, M.2    Kim, S.W.3
  • 19
    • 0346846666 scopus 로고    scopus 로고
    • Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats
    • Choi, S., Kim, S.W.: Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats. Pharm. Res. 20(12), 2008–2010 (2003)
    • (2003) Pharm. Res. , vol.20 , Issue.12 , pp. 2008-2010
    • Choi, S.1    Kim, S.W.2
  • 20
    • 34247637887 scopus 로고    scopus 로고
    • New hydrolysis-dependent thermosensitive polymer for an injectable degradable system
    • Cui, Z., Lee, B.H., Vernon, B.L.: New hydrolysis-dependent thermosensitive polymer for an injectable degradable system. Biomacromolecules 8(4), 1280–1286 (2007)
    • (2007) Biomacromolecules , vol.8 , Issue.4 , pp. 1280-1286
    • Cui, Z.1    Lee, B.H.2    Vernon, B.L.3
  • 21
    • 34848813257 scopus 로고    scopus 로고
    • Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities
    • Dimitrov, I., Trzebicka, B., Müller, A.H., Dworak, A., Tsvetanov, C.B.: Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities. Prog. Polym. Sci. 32(11), 1275–1343 (2007)
    • (2007) Prog. Polym. Sci. , vol.32 , Issue.11 , pp. 1275-1343
    • Dimitrov, I.1    Trzebicka, B.2    Müller, A.H.3    Dworak, A.4    Tsvetanov, C.B.5
  • 22
    • 0036532975 scopus 로고    scopus 로고
    • Study on pH-sensitive and thermosensitive polymer networks containing polyacetal segments
    • Du, J., Peng, Y., Zhang, T., Ding, X., Zheng, Z.: Study on pH-sensitive and thermosensitive polymer networks containing polyacetal segments. J. Appl. Polym. Sci. Symp. 83(14), 3002–3006 (2002)
    • (2002) J. Appl. Polym. Sci. Symp. , vol.83 , Issue.14 , pp. 3002-3006
    • Du, J.1    Peng, Y.2    Zhang, T.3    Ding, X.4    Zheng, Z.5
  • 23
    • 77955167174 scopus 로고    scopus 로고
    • Injectable pH-and temperature-responsive Poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers for delivery of angiogenic growth factors
    • Garbern, J.C., Hoffman, A.S., Stayton, P.S.: Injectable pH-and temperature-responsive Poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers for delivery of angiogenic growth factors. Biomacromolecules 11(7), 1833–1839 (2010)
    • (2010) Biomacromolecules , vol.11 , Issue.7 , pp. 1833-1839
    • Garbern, J.C.1    Hoffman, A.S.2    Stayton, P.S.3
  • 25
    • 0742268503 scopus 로고    scopus 로고
    • Biomodification of thermosensitive copolymer of ethylene glycol vinyl ether by RGD and insulin
    • Gümüsderelioglu, M., Müftüoglu, O., Gönen Karakeçili, A.: Biomodification of thermosensitive copolymer of ethylene glycol vinyl ether by RGD and insulin. React. Funct. Polym. 58(2), 149–156 (2004)
    • (2004) React. Funct. Polym. , vol.58 , Issue.2 , pp. 149-156
    • Gümüsderelioglu, M.1    Müftüoglu, O.2    Gönen Karakeçili, A.3
  • 26
    • 0037161339 scopus 로고    scopus 로고
    • Biodegradable injectable in situ forming drug delivery systems
    • Hatefi, A., Amsden, B.: Biodegradable injectable in situ forming drug delivery systems. J. Control Release 80(1–3), 9–28 (2002)
    • (2002) J. Control Release , vol.80 , Issue.1-3 , pp. 9-28
    • Hatefi, A.1    Amsden, B.2
  • 27
    • 0028336415 scopus 로고
    • Structural analysis and degradation behavior in polyethylene glycol/poly(L-lactide) copolymers
    • Hu, D.S., Liu, H.: Structural analysis and degradation behavior in polyethylene glycol/poly(L-lactide) copolymers. J. Appl. Polym. Sci. Symp. 51(3), 473–482 (1994)
    • (1994) J. Appl. Polym. Sci. Symp. , vol.51 , Issue.3 , pp. 473-482
    • Hu, D.S.1    Liu, H.2
  • 29
    • 0030131059 scopus 로고    scopus 로고
    • In vitro biocompatibility of bioresorbable polymers: Poly(L, DL-lactide) and poly(L-lactide-co-glycolide)
    • Ignatius, A.A., Claes, L.E.: In vitro biocompatibility of bioresorbable polymers: poly(L, DL-lactide) and poly(L-lactide-co-glycolide). Biomaterials 17(8), 831–839 (1996)
    • (1996) Biomaterials , vol.17 , Issue.8 , pp. 831-839
    • Ignatius, A.A.1    Claes, L.E.2
  • 30
    • 12144259315 scopus 로고    scopus 로고
    • Geneva, Switzerland. Test for local effects after implantation Part 6
    • International Organization for Standardization. (2007) Biological evaluation of medical devices. Geneva, Switzerland. Test for local effects after implantation Part 6.
    • (2007) Biological Evaluation of Medical Devices
  • 31
    • 30644460755 scopus 로고    scopus 로고
    • Overview literature on matrix assisted laser desorption ionization mass spectroscopy (MALDI MS): Basics and its applications in characterizing polymeric materials
    • Jagtap, R.N., Ambre, A.H.: Overview literature on matrix assisted laser desorption ionization mass spectroscopy (MALDI MS): basics and its applications in characterizing polymeric materials. Bull Mater. Sci. 28(6), 515–528 (2005)
    • (2005) Bull Mater. Sci. , vol.28 , Issue.6 , pp. 515-528
    • Jagtap, R.N.1    Ambre, A.H.2
  • 32
    • 0001319478 scopus 로고    scopus 로고
    • Biodegradable block copolymers as injectable drug-delivery systems
    • Jeong, B., Bae, Y.H., Lee, D.S., Kim, S.W.: Biodegradable block copolymers as injectable drug-delivery systems. Nature 388(6645), 860–862 (1997)
    • (1997) Nature , vol.388 , Issue.6645 , pp. 860-862
    • Jeong, B.1    Bae, Y.H.2    Lee, D.S.3    Kim, S.W.4
  • 33
    • 0345411651 scopus 로고    scopus 로고
    • Biodegradable thermosensitive micelles of PEG–PLGA– PEG triblock copolymers
    • Jeong, B., Bae, Y.H., Kim, S.W.: Biodegradable thermosensitive micelles of PEG–PLGA– PEG triblock copolymers. Colloids Surf. B Biointerf. 16(1–4), 185–193 (1999)
    • (1999) Colloids Surf. B Biointerf. , vol.16 , Issue.1-4 , pp. 185-193
    • Jeong, B.1    Bae, Y.H.2    Kim, S.W.3
  • 34
    • 0033204239 scopus 로고    scopus 로고
    • Thermoreversible gelation of PEG–PLGA–PEG triblock copolymer aqueous solutions
    • Jeong, B., Bae, Y.H., Kim, S.W.: Thermoreversible gelation of PEG–PLGA–PEG triblock copolymer aqueous solutions. Macromolecules 32(21), 7064–7069 (1999)
    • (1999) Macromolecules , vol.32 , Issue.21 , pp. 7064-7069
    • Jeong, B.1    Bae, Y.H.2    Kim, S.W.3
  • 35
    • 0034292138 scopus 로고    scopus 로고
    • Thermogelling biodegradable polymers with hydrophilic backbones: PEG-g-PLGA
    • Jeong, B., Kibbey, M.R., Birnbaum, J.C., Won, Y., Gutowska, A.: Thermogelling biodegradable polymers with hydrophilic backbones: PEG-g-PLGA. Macromolecules 33(22), 8317–8322 (2000)
    • (2000) Macromolecules , vol.33 , Issue.22 , pp. 8317-8322
    • Jeong, B.1    Kibbey, M.R.2    Birnbaum, J.C.3    Won, Y.4    Gutowska, A.5
  • 36
    • 0034948794 scopus 로고    scopus 로고
    • Controlled release of insulin from injectable biodegradable triblock copolymer
    • Kim, Y.J., Choi, S., Koh, J.J., Lee, M., Ko, K.S., Kim, S.W.: Controlled release of insulin from injectable biodegradable triblock copolymer. Pharm. Res. 18(4), 548–550 (2001)
    • (2001) Pharm. Res , vol.18 , Issue.4 , pp. 548-550
    • Kim, Y.J.1    Choi, S.2    Koh, J.J.3    Lee, M.4    Ko, K.S.5    Kim, S.W.6
  • 37
    • 33749169797 scopus 로고    scopus 로고
    • Preparation and characterization of MPEG-PCL diblock copolymers with thermo-responsive sol–gel–sol phase transition
    • Kim, M.S., Hyun, H., Seo, K.S., Cho, Y.H., Won Lee, J., Rae Lee, C., Khang, G., Lee, H.B.: Preparation and characterization of MPEG-PCL diblock copolymers with thermo-responsive sol–gel–sol phase transition. J. Polym. Sci. A. Polym. Chem. 44, 5413–5423 (2006)
    • (2006) J. Polym. Sci. A. Polym. Chem. , vol.44 , pp. 5413-5423
    • Kim, M.S.1    Hyun, H.2    Seo, K.S.3    Cho, Y.H.4    Won Lee, J.5    Rae Lee, C.6    Khang, G.7    Lee, H.B.8
  • 38
    • 0037161330 scopus 로고    scopus 로고
    • Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone
    • Kim, M.R., Park, T.G.: Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone. J. Control Release 80(1–3), 69–77 (2002)
    • (2002) J. Control Release , vol.80 , Issue.1-3 , pp. 69-77
    • Kim, M.R.1    Park, T.G.2
  • 39
    • 1242337280 scopus 로고    scopus 로고
    • Biodegradable triblock copolymer microspheres based on thermosensitive sol–gel transition
    • Kwon, Y.M., Kim, S.W.: Biodegradable triblock copolymer microspheres based on thermosensitive sol–gel transition. Pharm. Res. 21(2), 339–343 (2004)
    • (2004) Pharm. Res. , vol.21 , Issue.2 , pp. 339-343
    • Kwon, Y.M.1    Kim, S.W.2
  • 40
    • 0037140533 scopus 로고    scopus 로고
    • Synthesis and characterization of thermosensitive Poly(Organophosphazenes) with methoxy-poly(ethylene glycol) and akylamines as side groups
    • Lee, B.H., Lee, Y.M., Sohn, Y.S., Song, S.: Synthesis and characterization of thermosensitive Poly(organophosphazenes) with methoxy-poly(ethylene glycol) and akylamines as side groups. Bull. Korean Chem. Soc. 23(4), 549–554 (2002)
    • (2002) Bull. Korean Chem. Soc. , vol.23 , Issue.4 , pp. 549-554
    • Lee, B.H.1    Lee, Y.M.2    Sohn, Y.S.3    Song, S.4
  • 41
    • 0141726814 scopus 로고    scopus 로고
    • ATRP synthesis of amphiphilic random, gradient, and block copolymers of 2-(Dimethylamino)ethyl methacrylate and n-butyl methacrylate in aqueous media
    • Lee, S.B., Russell, A.J., Matyjaszewski, K.: ATRP synthesis of amphiphilic random, gradient, and block copolymers of 2-(Dimethylamino)ethyl methacrylate and n-butyl methacrylate in aqueous media. Biomacromolecules 4(5), 1386–1393 (2003)
    • (2003) Biomacromolecules , vol.4 , Issue.5 , pp. 1386-1393
    • Lee, S.B.1    Russell, A.J.2    Matyjaszewski, K.3
  • 42
    • 33847316531 scopus 로고    scopus 로고
    • New biodegradable thermogelling copolymers having very low gelation concentrations
    • Loh, X.J., Goh, S.H., Li, J.: New biodegradable thermogelling copolymers having very low gelation concentrations. Biomacromolecules 8(2), 585–593 (2007)
    • (2007) Biomacromolecules , vol.8 , Issue.2 , pp. 585-593
    • Loh, X.J.1    Goh, S.H.2    Li, J.3
  • 43
    • 0032509832 scopus 로고    scopus 로고
    • Diffusion studies of methotrexate in Carbopol and Poloxamer gels
    • Lu, G., Jun, H.W.: Diffusion studies of methotrexate in Carbopol and Poloxamer gels. Int. J. Pharm. 160(1), 1–9 (1998)
    • (1998) Int. J. Pharm. , vol.160 , Issue.1 , pp. 1-9
    • Lu, G.1    Jun, H.W.2
  • 44
    • 33749507042 scopus 로고    scopus 로고
    • Point by point comparison of two thermosensitive polymers exhibiting a similar LCST: Is the age of Poly(NIPAM) over?
    • Lutz, J., Akdemir, Ö., Hoth, A.: Point by point comparison of two thermosensitive polymers exhibiting a similar LCST: Is the age of Poly(NIPAM) over? J. Am. Chem. Soc. 128(40), 13046–13047 (2006)
    • (2006) J. Am. Chem. Soc. , vol.128 , Issue.40 , pp. 13046-13047
    • Lutz, J.1    Akdemir, Ö.2    Hoth, A.3
  • 45
    • 56949090806 scopus 로고    scopus 로고
    • Recombinant protein production:Strategic technology and a vital research tool
    • Mahmoud, K.: Recombinant protein production:strategic technology and a vital research tool. Res. J. Cell Mol. Biol. 1(1), 9–22 (2007)
    • (2007) Res. J. Cell Mol. Biol. , vol.1 , Issue.1 , pp. 9-22
    • Mahmoud, K.1
  • 46
    • 14644404306 scopus 로고    scopus 로고
    • Alternative approach to the design of thermosensitive polymers: The addition of hydrophobic groups to the ends of hydrophilic polyether
    • Mori, T., Shiota, Y., Minagawa, K., Tanaka, M.: Alternative approach to the design of thermosensitive polymers: The addition of hydrophobic groups to the ends of hydrophilic polyether. J. Polym. Sci. A Polym. Chem. 43(5), 1007–1013 (2005)
    • (2005) J. Polym. Sci. a Polym. Chem. , vol.43 , Issue.5 , pp. 1007-1013
    • Mori, T.1    Shiota, Y.2    Minagawa, K.3    Tanaka, M.4
  • 47
    • 77952148649 scopus 로고    scopus 로고
    • Tailoring thermoreversible hyaluronan hydrogels by ‘‘click’’ chemistry and RAFT polymerization for cell and drug therapy
    • Mortisen, D., Peroglio, M., Alini, M., Eglin, D.: Tailoring thermoreversible hyaluronan hydrogels by ‘‘click’’ chemistry and RAFT polymerization for cell and drug therapy. Biomacromolecules 11(5), 1261–1272 (2010)
    • (2010) Biomacromolecules , vol.11 , Issue.5 , pp. 1261-1272
    • Mortisen, D.1    Peroglio, M.2    Alini, M.3    Eglin, D.4
  • 48
    • 0030949023 scopus 로고    scopus 로고
    • Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant
    • Müller, R.H., Rühl, D., Runge, S., Schulze-Forster, K., Mehnert, W.: Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant. Pharm. Res. 14(4), 458–462 (1997)
    • (1997) Pharm. Res. , vol.14 , Issue.4 , pp. 458-462
    • Müller, R.H.1    Rühl, D.2    Runge, S.3    Schulze-Forster, K.4    Mehnert, W.5
  • 49
    • 0343527232 scopus 로고    scopus 로고
    • Controlled release injectable liposomal gel of ibuprofen for epidural analgesia
    • Paavola, A., Kilpeläinen, I., Yliruusi, J., Rosenberg, P.: Controlled release injectable liposomal gel of ibuprofen for epidural analgesia. Int. J. Pharm. 199(1), 85–93 (2000)
    • (2000) Int. J. Pharm. , vol.199 , Issue.1 , pp. 85-93
    • Paavola, A.1    Kilpeläinen, I.2    Yliruusi, J.3    Rosenberg, P.4
  • 51
    • 40949091885 scopus 로고    scopus 로고
    • Nano-aggregate of thermosensitive chitosan-Pluronic for sustained release of hydrophobic drug
    • Park, K.M., Bae, J.W., Joung, Y.K., Shin, J.W., Park, K.D.: Nano-aggregate of thermosensitive chitosan-Pluronic for sustained release of hydrophobic drug. Colloids Surf. B Biointerf. 63(1), 1–6 (2008)
    • (2008) Colloids Surf. B Biointerf. , vol.63 , Issue.1 , pp. 1-6
    • Park, K.M.1    Bae, J.W.2    Joung, Y.K.3    Shin, J.W.4    Park, K.D.5
  • 52
    • 72149088227 scopus 로고    scopus 로고
    • Cationic and thermosensitive protamine conjugated gels for enhancing sustained human growth hormone delivery
    • Park, M., Chun, C., Ahn, S., Ki, M., Cho, C., Song, S.: Cationic and thermosensitive protamine conjugated gels for enhancing sustained human growth hormone delivery. Biomaterials 31(6), 1349–1359 (2010)
    • (2010) Biomaterials , vol.31 , Issue.6 , pp. 1349-1359
    • Park, M.1    Chun, C.2    Ahn, S.3    Ki, M.4    Cho, C.5    Song, S.6
  • 53
    • 44949238722 scopus 로고    scopus 로고
    • Injectable and sustained delivery of human growth hormone using chemically modified Pluronic copolymer hydrogels
    • Park, S.Y., Chung, H.J., Lee, Y., Park, T.G.: Injectable and sustained delivery of human growth hormone using chemically modified Pluronic copolymer hydrogels. Biotechnol. J. 3(5), 669–675 (2008)
    • (2008) Biotechnol. J. , vol.3 , Issue.5 , pp. 669-675
    • Park, S.Y.1    Chung, H.J.2    Lee, Y.3    Park, T.G.4
  • 54
    • 0042383353 scopus 로고    scopus 로고
    • Effect of sodium chloride on the release, absorption and safety of diclofenac sodium delivered by poloxamer gel
    • Park, Y., Yong, C.S., Kim, H., Rhee, J., Oh, Y., Kim, C., Choi, H.: Effect of sodium chloride on the release, absorption and safety of diclofenac sodium delivered by poloxamer gel. Int. J. Pharm. 263(1–2), 105–111 (2003)
    • (2003) Int. J. Pharm. , vol.263 , Issue.1-2 , pp. 105-111
    • Park, Y.1    Yong, C.S.2    Kim, H.3    Rhee, J.4    Oh, Y.5    Kim, C.6    Choi, H.7
  • 55
    • 0032934866 scopus 로고    scopus 로고
    • Modulating insulin-release profile from pH/thermosensitive polymeric beads through polymer molecular weight
    • Ramkissoon-Ganorkar, C., Liu, F., Baudys, M., Kim, S.W.: Modulating insulin-release profile from pH/thermosensitive polymeric beads through polymer molecular weight. J. Control Release 59(3), 287–298 (1999)
    • (1999) J. Control Release , vol.59 , Issue.3 , pp. 287-298
    • Ramkissoon-Ganorkar, C.1    Liu, F.2    Baudys, M.3    Kim, S.W.4
  • 56
    • 3843071010 scopus 로고    scopus 로고
    • In situ-forming hydrogels-review of temperature-sensitive systems
    • Ruel-Gariépy, E., Leroux, J.: In situ-forming hydrogels-review of temperature-sensitive systems. Eur. J. Pharm. Biopharm. 58(2), 409–426 (2004)
    • (2004) Eur. J. Pharm. Biopharm. , vol.58 , Issue.2 , pp. 409-426
    • Ruel-Gariépy, E.1    Leroux, J.2
  • 57
    • 33646105618 scopus 로고    scopus 로고
    • Synthesis and characterization of biocompatible poly(Organophosphazenes) aiming for local delivery of protein drugs
    • Seong, J., Jun, Y.J., Kim, B.M., Park, Y.M., Sohn, Y.S.: Synthesis and characterization of biocompatible poly(organophosphazenes) aiming for local delivery of protein drugs. Int. J. Pharm. 314(1), 90–96 (2006)
    • (2006) Int. J. Pharm. , vol.314 , Issue.1 , pp. 90-96
    • Seong, J.1    Jun, Y.J.2    Kim, B.M.3    Park, Y.M.4    Sohn, Y.S.5
  • 58
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive, M.S., Anderson, J.M.: Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev. 28(1), 5–24 (1997)
    • (1997) Adv. Drug Deliv. Rev. , vol.28 , Issue.1 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 59
    • 34447639976 scopus 로고    scopus 로고
    • Thermosensitive polymers: Synthesis, characterization, and delivery of proteins
    • Singh, S., Webster, D.C., Singh, J.: Thermosensitive polymers: synthesis, characterization, and delivery of proteins. Int. J. Pharm. 341(1–2), 68–77 (2007)
    • (2007) Int. J. Pharm. , vol.341 , Issue.1-2 , pp. 68-77
    • Singh, S.1    Webster, D.C.2    Singh, J.3
  • 62
    • 0033517611 scopus 로고    scopus 로고
    • Synthesis and characterization of injectable Poly(N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro
    • Stile, R.A., Burghardt, W.R., Healy, K.E.: Synthesis and characterization of injectable Poly(N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro. Macromolecules 32(22), 7370–7379 (1999)
    • (1999) Macromolecules , vol.32 , Issue.22 , pp. 7370-7379
    • Stile, R.A.1    Burghardt, W.R.2    Healy, K.E.3
  • 63
    • 70350046442 scopus 로고    scopus 로고
    • Photo-cross-linked hydrogels from thermoresponsive PEGMEMA–PPGMA–EGDMA copolymers containing multiple methacrylate groups: Mechanical property, swelling, protein release, and cytotoxicity
    • Tai, H., Howard, D., Takae, S., Wang, W., Vermonden, T., Hennink, W.E., Stayton, P.S., Hoffman, A.S., Endruweit, A., Alexander, C., Howdle, S.M., Shakesheff, K.M.: Photo-cross-linked hydrogels from thermoresponsive PEGMEMA–PPGMA–EGDMA copolymers containing multiple methacrylate groups: mechanical property, swelling, protein release, and cytotoxicity. Biomacromolecules 10(10), 2895–2903 (2009)
    • (2009) Biomacromolecules , vol.10 , Issue.10 , pp. 2895-2903
    • Tai, H.1    Howard, D.2    Takae, S.3    Wang, W.4    Vermonden, T.5    Hennink, W.E.6    Stayton, P.S.7    Hoffman, A.S.8    Endruweit, A.9    Alexander, C.10    Howdle, S.M.11    Shakesheff, K.M.12
  • 65
    • 57049086420 scopus 로고    scopus 로고
    • Biodegradable and biocompatible thermosensitive polymer based injectable implant for controlled release of protein
    • Tang, Y., Singh, J.: Biodegradable and biocompatible thermosensitive polymer based injectable implant for controlled release of protein. Int. J. Pharm. 365(1–2), 34–43 (2009)
    • (2009) Int. J. Pharm. , vol.365 , Issue.1-2 , pp. 34-43
    • Tang, Y.1    Singh, J.2
  • 66
    • 77949270236 scopus 로고    scopus 로고
    • Thermosensitive drug delivery system of salmon calcitonin: In vitro release, in vivo absorption, bioactivity and therapeutic efficacies
    • Tang, Y., Singh, J.: Thermosensitive drug delivery system of salmon calcitonin: In vitro release, in vivo absorption, bioactivity and therapeutic efficacies. Pharm. Res. 27(2), 272–284 (2010)
    • (2010) Pharm. Res. , vol.27 , Issue.2 , pp. 272-284
    • Tang, Y.1    Singh, J.2
  • 68
    • 33846163453 scopus 로고    scopus 로고
    • Rheological studies of thermosensitive triblock copolymer hydrogels
    • Vermonden, T., Besseling, N.A.M., van Steenbergen, M.J., Hennink, W.E.: Rheological studies of thermosensitive triblock copolymer hydrogels. Langmuir 22(24), 10180–10184 (2006)
    • (2006) Langmuir , vol.22 , Issue.24 , pp. 10180-10184
    • Vermonden, T.1    Besseling, N.A.M.2    van Steenbergen, M.J.3    Hennink, W.E.4
  • 70
    • 0032782071 scopus 로고    scopus 로고
    • Instability, stabilization, and formulation of liquid protein pharmaceuticals
    • Wang, W.: Instability, stabilization, and formulation of liquid protein pharmaceuticals. Int. J. Pharm. 185(2), 129–188 (1999)
    • (1999) Int. J. Pharm. , vol.185 , Issue.2 , pp. 129-188
    • Wang, W.1
  • 71
    • 77956621279 scopus 로고    scopus 로고
    • Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers
    • Wang, F., Li, Z., Khan, M., Tamama, K., Kuppusamy, P., Wagner, W.R., Sen, C.K., Guon, J.: Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers. Acta Biomater. 6(6), 1978–1991 (2010)
    • (2010) Acta Biomater , vol.6 , Issue.6 , pp. 1978-1991
    • Wang, F.1    Li, Z.2    Khan, M.3    Tamama, K.4    Kuppusamy, P.5    Wagner, W.R.6    Sen, C.K.7    Guon, J.8
  • 72
    • 77953711255 scopus 로고    scopus 로고
    • In situ formation of thermosensitive PNIPAAm-based hydrogels by Michael-type addition reaction
    • Wang, Z., Xu, X., Chen, C., Yun, L., Song, J., Zhang, X., Zhuo, R.: In situ formation of thermosensitive PNIPAAm-based hydrogels by Michael-type addition reaction. ACS Appl. Mater. Interf. 2(4), 1009–1018 (2010)
    • (2010) ACS Appl. Mater. Interf. , vol.2 , Issue.4 , pp. 1009-1018
    • Wang, Z.1    Xu, X.2    Chen, C.3    Yun, L.4    Song, J.5    Zhang, X.6    Zhuo, R.7
  • 73
    • 0141652926 scopus 로고    scopus 로고
    • Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats
    • Wasan, K.M., Subramanian, R., Kwong, M., Goldberg, I.J., Wright, T., Johnston, T.P.: Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. J. Pharm. Pharm. Sci. 6(2), 189–197 (2003)
    • (2003) J. Pharm. Pharm. Sci. , vol.6 , Issue.2 , pp. 189-197
    • Wasan, K.M.1    Subramanian, R.2    Kwong, M.3    Goldberg, I.J.4    Wright, T.5    Johnston, T.P.6
  • 74
    • 70349232194 scopus 로고    scopus 로고
    • Biodegradable poly(Epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system
    • Wei, X., Gong, C., Gou, M., Fu, S., Guo, Q., Shi, S., Luo, F., Guo, G., Qiu, L., Qiu, Z.: Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system. Int. J. Pharm. 381(1), 1–18 (2009)
    • (2009) Int. J. Pharm. , vol.381 , Issue.1 , pp. 1-18
    • Wei, X.1    Gong, C.2    Gou, M.3    Fu, S.4    Guo, Q.5    Shi, S.6    Luo, F.7    Guo, G.8    Qiu, L.9    Qiu, Z.10
  • 75
    • 33846804547 scopus 로고    scopus 로고
    • A thermosensitive hydrogel based on quaternized chitosan and poly(Ethylene glycol) for nasal drug delivery system
    • Wu, J., Wei, W., Wang, L., Su, Z., Ma, G.: A thermosensitive hydrogel based on quaternized chitosan and poly(ethylene glycol) for nasal drug delivery system. Biomaterials 28(13), 2220–2232 (2007)
    • (2007) Biomaterials , vol.28 , Issue.13 , pp. 2220-2232
    • Wu, J.1    Wei, W.2    Wang, L.3    Su, Z.4    Ma, G.5
  • 76
    • 50149120343 scopus 로고    scopus 로고
    • Fabrication of fast responsive, thermosensitive poly(N-isopropylacrylamide) hydrogels by using diethyl ether as precipitation agent
    • Xu, X., Wang, B., Wang, Z., Cheng, S., Zhang, X., Zhuo, R.: Fabrication of fast responsive, thermosensitive poly(N-isopropylacrylamide) hydrogels by using diethyl ether as precipitation agent. J. Biomed. Mater. Res. A 86(4), 1023–1032 (2008)
    • (2008) J. Biomed. Mater. Res. A , vol.86 , Issue.4 , pp. 1023-1032
    • Xu, X.1    Wang, B.2    Wang, Z.3    Cheng, S.4    Zhang, X.5    Zhuo, R.6
  • 77
    • 77955571111 scopus 로고    scopus 로고
    • Biodegradability and biocompatibility of thermoreversible hydrogels formed from mixing a sol and a precipitate of block copolymers in water
    • Yu, L., Zhang, Z., Zhang, H., Ding, J.: Biodegradability and biocompatibility of thermoreversible hydrogels formed from mixing a sol and a precipitate of block copolymers in water. Biomacromolecules 11(8), 2169–2178 (2010)
    • (2010) Biomacromolecules , vol.11 , Issue.8 , pp. 2169-2178
    • Yu, L.1    Zhang, Z.2    Zhang, H.3    Ding, J.4
  • 78
    • 0032861804 scopus 로고    scopus 로고
    • Development of a thermo-reversible insulin liquid suppository with bioavailability enhancement
    • Yun, M., Choi, H., Jung, J., Kim, C.: Development of a thermo-reversible insulin liquid suppository with bioavailability enhancement. Int. J. Pharm. 189(2), 137–145 (1999)
    • (1999) Int. J. Pharm. , vol.189 , Issue.2 , pp. 137-145
    • Yun, M.1    Choi, H.2    Jung, J.3    Kim, C.4
  • 80
    • 67049158572 scopus 로고    scopus 로고
    • Effects of hydroxylpropyl-beta-cyclodextrin on in vitro insulin stability
    • Zhang, L., Zhu, W., Song, L., Wang, Y., Jiang, H., Xian, S., Ren, Y.: Effects of hydroxylpropyl-beta-cyclodextrin on in vitro insulin stability. Int. J. Mol. Sci. 10(5), 2031–2040 (2009)
    • (2009) Int. J. Mol. Sci. , vol.10 , Issue.5 , pp. 2031-2040
    • Zhang, L.1    Zhu, W.2    Song, L.3    Wang, Y.4    Jiang, H.5    Xian, S.6    Ren, Y.7
  • 81
    • 27444444311 scopus 로고    scopus 로고
    • Ruthenium-centered thermosensitive polymers
    • Zhou, G., Harruna, I.I., Ingram, C.W.: Ruthenium-centered thermosensitive polymers. Polymer 46(24), 10672–10677 (2005)
    • (2005) Polymer , vol.46 , Issue.24 , pp. 10672-10677
    • Zhou, G.1    Harruna, I.I.2    Ingram, C.W.3


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