Modulating insulin-release profile from pH/thermosensitive polymeric beads through polymer molecular weight

Journal of Controlled Release

Volumn 59, Issue 3, 1999, Pages 287-298

  Ramkissoon Ganorkar, Chaaya ^a   Liu, Feng ^a   Baudyš, Miroslav ^a   Kim, Sung Wan ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

pH temperature sensitive; Poly(N isopropylacrylamide); Polymeric beads; Protein peptide oral delivery; Swelling dissolution controlled

Indexed keywords

INSULIN; NANOPARTICLE; POLYMER;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; HEAT SENSITIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSULIN RELEASE; MOLECULAR WEIGHT; NONHUMAN; PH; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; INSULIN; MICROSPHERES; MOLECULAR WEIGHT; POLYMERS; PROTEINS; TEMPERATURE;

EID: 0032934866     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00006-1     Document Type: Article

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