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Volumn 78, Issue 10, 2004, Pages 5205-5215

The V1/V2 Domain of gp120 Is a Global Regulator of the Sensitivity of Primary Human Immunodeficiency Virus Type 1 Isolates to Neutralization by Antibodies Commonly Induced upon Infection

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD4 ANTIGEN; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN G B12; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2F5; MONOCLONAL ANTIBODY 2G12; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

EID: 2342644898     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.10.5205-5215.2004     Document Type: Article
Times cited : (233)

References (58)
  • 2
    • 0032509888 scopus 로고    scopus 로고
    • Viral envelope fails to deliver?
    • Bolognesi, D. P., and T. J. Matthews. 1998. Viral envelope fails to deliver? Nature 391:638-639.
    • (1998) Nature , vol.391 , pp. 638-639
    • Bolognesi, D.P.1    Matthews, T.J.2
  • 5
    • 0030812563 scopus 로고    scopus 로고
    • Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein
    • Cao, J., N. Sullivan, E. Desjardin, C. Parolin, J. Robinson, R. Wyatt, and J. Sodroski. 1997. Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein. J. Virol. 71:9808-9812.
    • (1997) J. Virol. , vol.71 , pp. 9808-9812
    • Cao, J.1    Sullivan, N.2    Desjardin, E.3    Parolin, C.4    Robinson, J.5    Wyatt, R.6    Sodroski, J.7
  • 6
    • 0031818178 scopus 로고    scopus 로고
    • Neutralization profiles of primary human immunodeficiency virus type 1 isolates in the context of coreceptor usage
    • Cecilia, D., V. N. KewalRamani, J. O'Leary, B. Volsky, P. Nyambi, S. Burda, S. Xu, L. D. R., and S. Zolla-Pazner. 1998. Neutralization profiles of primary human immunodeficiency virus type 1 isolates in the context of coreceptor usage. J. Virol. 72:6988-6996.
    • (1998) J. Virol. , vol.72 , pp. 6988-6996
    • Cecilia, D.1    KewalRamani, V.N.2    O'Leary, J.3    Volsky, B.4    Nyambi, P.5    Burda, S.6    Xu, S.7    Zolla-Pazner, S.8
  • 7
    • 0028009774 scopus 로고
    • Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses
    • Chen, B. K., K. Saksela, R. Andino, and D. Baltimore. 1994. Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses. J. Virol. 68:654-660.
    • (1994) J. Virol. , vol.68 , pp. 654-660
    • Chen, B.K.1    Saksela, K.2    Andino, R.3    Baltimore, D.4
  • 8
    • 0033033625 scopus 로고    scopus 로고
    • SF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation
    • SF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation. J. Virol. 73:5294-5300.
    • (1999) J. Virol. , vol.73 , pp. 5294-5300
    • Cheng-Mayer, C.1    Brown, A.2    Harouse, J.3    Luciw, P.A.4    Mayer, A.J.5
  • 9
    • 0025004459 scopus 로고
    • Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation
    • Cheng-Mayer, C., M. Quiroga, J. W. Tung, D. Dina, and J. A. Levy. 1990. Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation. J. Virol. 64:4390-4398.
    • (1990) J. Virol. , vol.64 , pp. 4390-4398
    • Cheng-Mayer, C.1    Quiroga, M.2    Tung, J.W.3    Dina, D.4    Levy, J.A.5
  • 10
    • 0012041487 scopus 로고
    • Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus
    • Cheng-Mayer, C., C. Weiss, D. Seto, and J. A. Levy. 1989. Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus. Proc. Natl. Acad. Sci. USA 86:8575-8579.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 8575-8579
    • Cheng-Mayer, C.1    Weiss, C.2    Seto, D.3    Levy, J.A.4
  • 11
    • 0037470407 scopus 로고    scopus 로고
    • Public health: AIDS vaccine trial produces disappointment and confusion
    • Cohen, J. 2003. Public health: AIDS vaccine trial produces disappointment and confusion. Science 299:1290-1291.
    • (2003) Science , vol.299 , pp. 1290-1291
    • Cohen, J.1
  • 13
    • 0028208268 scopus 로고
    • Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody
    • Conley, A. J., J. A. Kessler II, L. J. Boots, J.-S. Tung, B. A. Arnold, P. M. Keller, A. R. Shaw, and E. A. Emini. 1994. Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody. Proc. Natl. Acad. Sci. USA 91:3348-3352.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3348-3352
    • Conley, A.J.1    Kessler II, J.A.2    Boots, L.J.3    Tung, J.-S.4    Arnold, B.A.5    Keller, P.M.6    Shaw, A.R.7    Emini, E.A.8
  • 15
    • 0030897825 scopus 로고    scopus 로고
    • Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex
    • Fouts, T. R., J. M. Binley, A. Trkola, J. E. Robinson, and J. P. Moore. 1997. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex. J. Virol. 71:2779-2785.
    • (1997) J. Virol. , vol.71 , pp. 2779-2785
    • Fouts, T.R.1    Binley, J.M.2    Trkola, A.3    Robinson, J.E.4    Moore, J.P.5
  • 16
    • 0027267428 scopus 로고
    • Envelope glycoproteins of HIV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses
    • Gilljam, G. 1993. Envelope glycoproteins of HIV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses. AIDS Res. Hum. Retrovir. 9:431.
    • (1993) AIDS Res. Hum. Retrovir. , vol.9 , pp. 431
    • Gilljam, G.1
  • 17
    • 0005534134 scopus 로고
    • Production of human monoclonal antibodies via fusion of Epstein-Barr virus-transformed lymphocytes with heteromyeloma
    • J. E. Celis (ed.), Academic Press, San Diego, Calif
    • Gorny, M. K. 1994. Production of human monoclonal antibodies via fusion of Epstein-Barr virus-transformed lymphocytes with heteromyeloma, p. 276-281. In J. E. Celis (ed.), Cell biology: a laboratory handbook, vol. 2. Academic Press, San Diego, Calif.
    • (1994) Cell Biology: A Laboratory Handbook , vol.2 , pp. 276-281
    • Gorny, M.K.1
  • 19
    • 0036720793 scopus 로고    scopus 로고
    • Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades
    • Gorny, M. K., C. Williams, B. Volsky, K. Revesz, S. Cohen, V. R. Polonis, W. J. Honnen, S. C. Kayman, C. Krachmarov, A. Pinter, and S. Zolla-Pazner. 2002. Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades. J. Virol. 76:9035-9045.
    • (2002) J. Virol. , vol.76 , pp. 9035-9045
    • Gorny, M.K.1    Williams, C.2    Volsky, B.3    Revesz, K.4    Cohen, S.5    Polonis, V.R.6    Honnen, W.J.7    Kayman, S.C.8    Krachmarov, C.9    Pinter, A.10    Zolla-Pazner, S.11
  • 22
    • 0036644329 scopus 로고    scopus 로고
    • Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human IG loci
    • He, Y., W. J. Honnen, C. P. Krachmarov, M. Burkhart, S. C. Kayman, J. Corvalan, and A. Pinter. 2002. Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human IG loci. J. Immunol. 169:595-605.
    • (2002) J. Immunol. , vol.169 , pp. 595-605
    • He, Y.1    Honnen, W.J.2    Krachmarov, C.P.3    Burkhart, M.4    Kayman, S.C.5    Corvalan, J.6    Pinter, A.7
  • 23
    • 0036167956 scopus 로고    scopus 로고
    • A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope
    • Johnson, W. E., J. Morgan, J. Reitter, B. A. Puffer, S. Czajak, R. W. Doms, and R. C. Desrosiers. 2002. A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope. J. Virol. 76:2075-2086.
    • (2002) J. Virol. , vol.76 , pp. 2075-2086
    • Johnson, W.E.1    Morgan, J.2    Reitter, J.3    Puffer, B.A.4    Czajak, S.5    Doms, R.W.6    Desrosiers, R.C.7
  • 24
    • 0141458878 scopus 로고    scopus 로고
    • Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities
    • Johnson, W. E., H. Sanford, L. Schwall, D. R. Burton, P. W. Parren, J. E. Robinson, and R. C. Desrosiers. 2003. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. J. Virol. 77:9993-10003.
    • (2003) J. Virol. , vol.77 , pp. 9993-10003
    • Johnson, W.E.1    Sanford, H.2    Schwall, L.3    Burton, D.R.4    Parren, P.W.5    Robinson, J.E.6    Desrosiers, R.C.7
  • 25
    • 84959850495 scopus 로고
    • Clinical, immunologic, and virologic observations related to human immunodeficiency virus (HIV) type 1 infection in a volunteer in an HIV-1 vaccine clinical trial
    • Kahn, J., K. S. Steimer, J. Baenziger, A. M. Duliege, M. Feinberg, T. Elbeik, M. Chesney, N. Murcar, D. Chernoff, and F. Sinangil. 1995. Clinical, immunologic, and virologic observations related to human immunodeficiency virus (HIV) type 1 infection in a volunteer in an HIV-1 vaccine clinical trial. J. Infect. Dis. 171:1343-1347.
    • (1995) J. Infect. Dis. , vol.171 , pp. 1343-1347
    • Kahn, J.1    Steimer, K.S.2    Baenziger, J.3    Duliege, A.M.4    Feinberg, M.5    Elbeik, T.6    Chesney, M.7    Murcar, N.8    Chernoff, D.9    Sinangil, F.10
  • 26
    • 0028097964 scopus 로고
    • Presentation of native epitopes in the V1/V2 and V3 domains of HIV-1 gp120 by fusion glycoproteins containing fragments of gp120
    • Kayman, S. C., Z. Wu, K. Revesz, H.-C. Chen, R. Kopelman, and A. Pinter. 1994. Presentation of native epitopes in the V1/V2 and V3 domains of HIV-1 gp120 by fusion glycoproteins containing fragments of gp120. J. Virol. 68: 400-410.
    • (1994) J. Virol. , vol.68 , pp. 400-410
    • Kayman, S.C.1    Wu, Z.2    Revesz, K.3    Chen, H.-C.4    Kopelman, R.5    Pinter, A.6
  • 27
    • 0029655566 scopus 로고    scopus 로고
    • Quantitative analysis of serum neutralization of human immunodeficiency virus type 1 from subtypes A, B, C, D, E, F, and I: Lack of direct correlation between neutralization serotypes and genetic subtypes and evidence for prevalent serum-dependent infectivity enhancement
    • Kostrikis, L. G., Y. Cao, H. Ngai, J. P. Moore, and D. D. Ho. 1996. Quantitative analysis of serum neutralization of human immunodeficiency virus type 1 from subtypes A, B, C, D, E, F, and I: lack of direct correlation between neutralization serotypes and genetic subtypes and evidence for prevalent serum-dependent infectivity enhancement. J. Virol. 70:445-458.
    • (1996) J. Virol. , vol.70 , pp. 445-458
    • Kostrikis, L.G.1    Cao, Y.2    Ngai, H.3    Moore, J.P.4    Ho, D.D.5
  • 28
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • Koyanagi, Y., S. Miles, R. T. Mitsuyasu, J. E. Merrill, H. V. Vinters, and I. S. Chen. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.T.3    Merrill, J.E.4    Vinters, H.V.5    Chen, I.S.6
  • 29
    • 0035701793 scopus 로고    scopus 로고
    • V3-specific polyclonal antibodies affinity purified from sera of infected humans effectively neutralize primary isolates of human immunodeficiency virus type 1
    • Krachmarov, C. P., S. C. Kayman, W. J. Honnen, O. Trochev, and A. Pinter. 2001. V3-specific polyclonal antibodies affinity purified from sera of infected humans effectively neutralize primary isolates of human immunodeficiency virus type 1. AIDS Res. Hum. Retrovir. 17:1737-1748.
    • (2001) AIDS Res. Hum. Retrovir. , vol.17 , pp. 1737-1748
    • Krachmarov, C.P.1    Kayman, S.C.2    Honnen, W.J.3    Trochev, O.4    Pinter, A.5
  • 31
    • 0032543307 scopus 로고    scopus 로고
    • Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
    • Kwong, P. D., R. Wyatt, J. Robinson, R. W. Sweet, J. Sodroski, and W. A. Hendrickson. 1998. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393:648-659.
    • (1998) Nature , vol.393 , pp. 648-659
    • Kwong, P.D.1    Wyatt, R.2    Robinson, J.3    Sweet, R.W.4    Sodroski, J.5    Hendrickson, W.A.6
  • 32
    • 0033919404 scopus 로고    scopus 로고
    • Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus
    • Kwong, P. D., R. Wyatt, Q. J. Sattentau, J. Sodroski, and W. A. Hendrickson. 2000. Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus. J. Virol. 74:1961-1972.
    • (2000) J. Virol. , vol.74 , pp. 1961-1972
    • Kwong, P.D.1    Wyatt, R.2    Sattentau, Q.J.3    Sodroski, J.4    Hendrickson, W.A.5
  • 34
    • 0033942750 scopus 로고    scopus 로고
    • V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies
    • Ly, A., and L. Stamatatos. 2000. V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies. J. Virol. 74:6769-6776.
    • (2000) J. Virol. , vol.74 , pp. 6769-6776
    • Ly, A.1    Stamatatos, L.2
  • 37
    • 0031951649 scopus 로고    scopus 로고
    • Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage
    • Montefiori, D. C., R. G. Collman, T. R. Fouts, J. Y. Zhou, M. Bilska, J. A. Hoxie, J. P. Moore, and D. P. Bolognesi. 1998. Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage. J. Virol. 72: 1886-1893.
    • (1998) J. Virol. , vol.72 , pp. 1886-1893
    • Montefiori, D.C.1    Collman, R.G.2    Fouts, T.R.3    Zhou, J.Y.4    Bilska, M.5    Hoxie, J.A.6    Moore, J.P.7    Bolognesi, D.P.8
  • 38
    • 0028917784 scopus 로고
    • Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
    • Moore, J. P., Y. Cao, L. Qing, Q. J. Sattentau, J. Pyati, R. Koduri, J. Robinson, C. F. Barbas III, D. R. Burton, and D. D. Ho. 1995. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J. Virol. 69:101-109.
    • (1995) J. Virol. , vol.69 , pp. 101-109
    • Moore, J.P.1    Cao, Y.2    Qing, L.3    Sattentau, Q.J.4    Pyati, J.5    Koduri, R.6    Robinson, J.7    Barbas III, C.F.8    Burton, D.R.9    Ho, D.D.10
  • 39
    • 0030694769 scopus 로고    scopus 로고
    • The V1/V2 region of human immunodeficiency virus type 1 modulates the sensitivity to neutralization by soluble CD4 and cellular tropism
    • Morikita, T., Y. Maeda, S.-I. Fujii, S. Matsushita, K. Obaru, and K. Takat. suki. 1997. The V1/V2 region of human immunodeficiency virus type 1 modulates the sensitivity to neutralization by soluble CD4 and cellular tropism. AIDS Res. Hum. Retrovir. 13:1291-1299.
    • (1997) AIDS Res. Hum. Retrovir. , vol.13 , pp. 1291-1299
    • Morikita, T.1    Maeda, Y.2    Fujii, S.-I.3    Matsushita, S.4    Obaru, K.5    Takatsuki, K.6
  • 42
    • 0025065099 scopus 로고
    • HIV-1 tropism for mononuclear phagocytes can be determined by regions outside the CD4-binding domain
    • O'Brien, W. A., Y. Koyanagi, A. Namazie, J.-Q. Zhao, A. Diagne, K. Idler, J. A. Zack, and I. S. Y. Chen. 1990. HIV-1 tropism for mononuclear phagocytes can be determined by regions outside the CD4-binding domain. Nature 348:69-73.
    • (1990) Nature , vol.348 , pp. 69-73
    • O'Brien, W.A.1    Koyanagi, Y.2    Namazie, A.3    Zhao, J.-Q.4    Diagne, A.5    Idler, K.6    Zack, J.A.7    Chen, I.S.Y.8
  • 43
    • 0027454080 scopus 로고
    • A potent, neutralizing human monoclonal antibody against a unique epitope overlapping the CD4-binding site of HIV-1 gp120 that is broadly conserved across North American and African virus isolates
    • Pinter, A., W. J. Honnen, M. E. Racho, and S. A. Tilley. 1993. A potent, neutralizing human monoclonal antibody against a unique epitope overlapping the CD4-binding site of HIV-1 gp120 that is broadly conserved across North American and African virus isolates. AIDS Res. Hum. Retrovir. 9:985-996.
    • (1993) AIDS Res. Hum. Retrovir. , vol.9 , pp. 985-996
    • Pinter, A.1    Honnen, W.J.2    Racho, M.E.3    Tilley, S.A.4
  • 44
    • 0027261552 scopus 로고
    • Conformational changes affecting the V3 and CD4-binding domains of human immunodeficiency virus type 1 gp120 associated with env processing and with binding of ligands to these sites
    • Pinter, A., W. J. Honnen, and S. A. Tilley. 1993. Conformational changes affecting the V3 and CD4-binding domains of human immunodeficiency virus type 1 gp120 associated with env processing and with binding of ligands to these sites. J. Virol. 67:5692-5697.
    • (1993) J. Virol. , vol.67 , pp. 5692-5697
    • Pinter, A.1    Honnen, W.J.2    Tilley, S.A.3
  • 45
    • 0036637385 scopus 로고    scopus 로고
    • The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120
    • Sanders, R. W., M. Venturi, L. Schiffner, R. Kalyanaraman, H. Katinger, K. O. Lloyd, P. D. Kwong, and J. P. Moore. 2002. The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120. J. Virol. 76:7293-7305.
    • (2002) J. Virol. , vol.76 , pp. 7293-7305
    • Sanders, R.W.1    Venturi, M.2    Schiffner, L.3    Kalyanaraman, R.4    Katinger, H.5    Lloyd, K.O.6    Kwong, P.D.7    Moore, J.P.8
  • 46
  • 47
    • 0031666180 scopus 로고    scopus 로고
    • An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades
    • Stamatatos, L., and C. Cheng-Mayer. 1998. An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades. J. Virol. 72:7840-7845.
    • (1998) J. Virol. , vol.72 , pp. 7840-7845
    • Stamatatos, L.1    Cheng-Mayer, C.2
  • 48
    • 0021041087 scopus 로고
    • Construction and testing of mouse-human heteromyelomas for human monoclonal antibody production
    • Teng, N. N., K. S. Lam, F. C. Riera, and H. S. Kaplan. 1983. Construction and testing of mouse-human heteromyelomas for human monoclonal antibody production. Proc. Natl. Acad. Sci. USA 80:7308-7312.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 7308-7312
    • Teng, N.N.1    Lam, K.S.2    Riera, F.C.3    Kaplan, H.S.4
  • 49
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali, M., J. P. Moore, C. Furman, M. Charles, D. D. Ho, J. Robinson, and J. Sodroski. 1993. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J. Virol. 67:3978-3988.
    • (1993) J. Virol. , vol.67 , pp. 3978-3988
    • Thali, M.1    Moore, J.P.2    Furman, C.3    Charles, M.4    Ho, D.D.5    Robinson, J.6    Sodroski, J.7
  • 50
    • 0025821179 scopus 로고
    • A human monoclonal antibody against the CD4 binding site of HIV-1 gp120 exhibits potent, broadly neutralizing activity
    • Tilley, S. A., W. J. Honnen, M. E. Racho, M. Hilgartner, and A. Pinter. 1991. A human monoclonal antibody against the CD4 binding site of HIV-1 gp120 exhibits potent, broadly neutralizing activity. Res. Virol. 142:247-259.
    • (1991) Res. Virol. , vol.142 , pp. 247-259
    • Tilley, S.A.1    Honnen, W.J.2    Racho, M.E.3    Hilgartner, M.4    Pinter, A.5
  • 54
    • 0035909909 scopus 로고    scopus 로고
    • The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012
    • Zhu, C. B., L. Zhu, S. Holz-Smith, T. J. Matthews, and C. H. Chen. 2001. The role of the third beta strand in gp120 conformation and neutralization sensitivity of the HIV-1 primary isolate DH012. Proc. Natl. Acad. Sci. USA 98:15227-15232.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 15227-15232
    • Zhu, C.B.1    Zhu, L.2    Holz-Smith, S.3    Matthews, T.J.4    Chen, C.H.5
  • 55
    • 0038618737 scopus 로고    scopus 로고
    • A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12
    • Zwick, M. B., R. Kelleher, R. Jensen, A. F. Labrijn, M. Wang, G. V. Quinnan, Jr., P. W. Parren, and D. R. Burton. 2003. A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12. J. Virol. 77:6965-6978.
    • (2003) J. Virol. , vol.77 , pp. 6965-6978
    • Zwick, M.B.1    Kelleher, R.2    Jensen, R.3    Labrijn, A.F.4    Wang, M.5    Quinnan Jr., G.V.6    Parren, P.W.7    Burton, D.R.8
  • 56
    • 12144285761 scopus 로고    scopus 로고
    • The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5
    • a. Zwick, M. B., H. K. Komori, R. L. Stanfield, S. Church, M. Wang, P. W. Parren, R. Kunert, H. Katinger, I. A. Wilson, and D. R. Burton. 2004. The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5. J. Virol. 78:3155-3161.
    • (2004) J. Virol. , vol.78 , pp. 3155-3161
    • Zwick, M.B.1    Komori, H.K.2    Stanfield, R.L.3    Church, S.4    Wang, M.5    Parren, P.W.6    Kunert, R.7    Katinger, H.8    Wilson, I.A.9    Burton, D.R.10
  • 58
    • 0038032955 scopus 로고    scopus 로고
    • Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120
    • Zwick, M. B., P. W. Parren, E. O. Saphire, S. Church, M. Wang, J. K. Scott, P. E. Dawson, I. A. Wilson, and D. R. Burton. 2003. Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120. J. Virol. 77:5863-5876.
    • (2003) J. Virol. , vol.77 , pp. 5863-5876
    • Zwick, M.B.1    Parren, P.W.2    Saphire, E.O.3    Church, S.4    Wang, M.5    Scott, J.K.6    Dawson, P.E.7    Wilson, I.A.8    Burton, D.R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.