Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis

Journal of Structural Biology

Volumn 184, Issue 2, 2013, Pages 115-128

  Wagner, Jonathan M ^a   Evans, Timothy J ^a   Chen, Jing ^a   Zhu, Haining ^a   Houben, Edith N G ^b   Bitter, Wilbert ^b   Korotkov, Konstantin V ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

EspB; ESX; M. tuberculosis; MycP; Subtilisin; Type VII secretion system

Indexed keywords

BACTERIAL ENZYME; MYCOSIN 1; MYCOSIN 3; PROTEINASE; SUBTILISIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL SECRETION SYSTEM; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; IN VITRO STUDY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECRETORY PATHWAY; TYPE VII SECRETION SYSTEM;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

ESPB; ESX; M. TUBERCULOSIS; MYCP; SUBTILISIN; TYPE VII SECRETION SYSTEM;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYSTINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; SUBTILISINS;

EID: 84887254092     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2013.09.022     Document Type: Article

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