메뉴 건너뛰기




Volumn 76, Issue 1, 2008, Pages 127-140

Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN LIPY; PROTEIN PE; PROTEIN PPE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

EID: 37749009652     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00410-07     Document Type: Article
Times cited : (115)

References (45)
  • 2
    • 34548475774 scopus 로고    scopus 로고
    • The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria
    • Alahari, A., N. Saint, S. Campagna, V. Molle, G. Molle, and L. Kremer. 2007. The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria. J. Bacteriol. 189:6351-6358.
    • (2007) J. Bacteriol , vol.189 , pp. 6351-6358
    • Alahari, A.1    Saint, N.2    Campagna, S.3    Molle, V.4    Molle, G.5    Kremer, L.6
  • 5
    • 0032247240 scopus 로고
    • Preparation of cell-wall fractions from mycobacteria
    • T. Parish and N. G. Stoker ed, Humana Press Inc, Totowa, NI
    • Besra, G. S. 1995. Preparation of cell-wall fractions from mycobacteria, p. 91-107. In T. Parish and N. G. Stoker (ed.), Methods in molecular biology, vol. 101. Humana Press Inc., Totowa, NI.
    • (1995) Methods in molecular biology , vol.101 , pp. 91-107
    • Besra, G.S.1
  • 6
    • 27744492218 scopus 로고    scopus 로고
    • Bhatt, A., L. Kremer, A. Z. Dai, J. C. Sacchettini, and W. R. Jacobs, Jr. 2005. Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis. J. Bacteriol. 187:7596-7606.
    • Bhatt, A., L. Kremer, A. Z. Dai, J. C. Sacchettini, and W. R. Jacobs, Jr. 2005. Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis. J. Bacteriol. 187:7596-7606.
  • 7
    • 77049286017 scopus 로고
    • Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro
    • Bloch, H., and W. Segal. 1956. Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro. J. Bacteriol. 72:132-141.
    • (1956) J. Bacteriol , vol.72 , pp. 132-141
    • Bloch, H.1    Segal, W.2
  • 8
    • 33646923704 scopus 로고    scopus 로고
    • Identification of Staphylococcus aureus proteins recognized by the antibody-mediated immune response to a biofilm infection
    • Brady, R. A., J. G. Leid, A. K. Camper, J. W. Costerton, and M. E. Shirtliff. 2006. Identification of Staphylococcus aureus proteins recognized by the antibody-mediated immune response to a biofilm infection. Infect. Immun. 74:3415-3426.
    • (2006) Infect. Immun , vol.74 , pp. 3415-3426
    • Brady, R.A.1    Leid, J.G.2    Camper, A.K.3    Costerton, J.W.4    Shirtliff, M.E.5
  • 9
    • 0036568632 scopus 로고    scopus 로고
    • The PE multigene family: A 'molecular mantra' for mycobacteria
    • Brennan, M. J., and G. Delogu. 2002. The PE multigene family: a 'molecular mantra' for mycobacteria. Trends Microbiol. 10:246-249.
    • (2002) Trends Microbiol , vol.10 , pp. 246-249
    • Brennan, M.J.1    Delogu, G.2
  • 10
    • 0035177858 scopus 로고    scopus 로고
    • Brennan, M. J., G. Delogu, Y. Chen, S. Bardarov, J. Kriakov, M. Alavi, and W. R. Jacobs, Jr. 2001. Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells. Infect. Immun. 69:7326-7333.
    • Brennan, M. J., G. Delogu, Y. Chen, S. Bardarov, J. Kriakov, M. Alavi, and W. R. Jacobs, Jr. 2001. Evidence that mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells. Infect. Immun. 69:7326-7333.
  • 11
    • 29644443846 scopus 로고    scopus 로고
    • The PE and PPE multigene families of mycobacteria
    • S. T. Cole et al, ed, American Society for Microbiology, Washington, DC
    • Brennan, M. J., N. C. G. van Pittius, and C. Espitia. 2005. The PE and PPE multigene families of mycobacteria, p. 513-525. In S. T. Cole et al. (ed.), Tuberculosis and the tubercle bacillus. American Society for Microbiology, Washington, DC.
    • (2005) Tuberculosis and the tubercle bacillus , pp. 513-525
    • Brennan, M.J.1    van Pittius, N.C.G.2    Espitia, C.3
  • 13
    • 4644269598 scopus 로고    scopus 로고
    • Regions of high antigenicity within the hypothetical PPE major polymorphic tandem repeat open-reading frame, Rv2608, show a differential humoral response and a low T cell response in various categories of patients with tuberculosis
    • Chakhaiyar, P., Y. Nagalakshmi, B. Aruna, K. J. Murthy, V. M. Katoch, and S. E. Hasnain. 2004. Regions of high antigenicity within the hypothetical PPE major polymorphic tandem repeat open-reading frame, Rv2608, show a differential humoral response and a low T cell response in various categories of patients with tuberculosis. J. Infect. Dis. 190:1237-1244.
    • (2004) J. Infect. Dis , vol.190 , pp. 1237-1244
    • Chakhaiyar, P.1    Nagalakshmi, Y.2    Aruna, B.3    Murthy, K.J.4    Katoch, V.M.5    Hasnain, S.E.6
  • 16
    • 0032508046 scopus 로고    scopus 로고
    • Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry III, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M. A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
    • Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry III, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M. A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
  • 17
    • 3242750587 scopus 로고    scopus 로고
    • Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture
    • Daniel, J., C. Deb, V. S. Dubey, T. D. Sirakova, B. Abomoelak, H. R. Morbidoni, and P. E. Kolattukudy. 2004. Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture. J. Bacteriol. 186:5017-5030.
    • (2004) J. Bacteriol , vol.186 , pp. 5017-5030
    • Daniel, J.1    Deb, C.2    Dubey, V.S.3    Sirakova, T.D.4    Abomoelak, B.5    Morbidoni, H.R.6    Kolattukudy, P.E.7
  • 18
    • 0141861069 scopus 로고    scopus 로고
    • The RD1 proteins of Mycobacterium tuberculosis: Expression in Mycobacterium smegmatis and biochemical characterization
    • Daugelat, S., J. Kowall, J. Mattow, D. Bumann, R. Winter, R. Hurwitz, and S. H. Kaufmann. 2003. The RD1 proteins of Mycobacterium tuberculosis: expression in Mycobacterium smegmatis and biochemical characterization. Microbes Infect. 5:1082-1095.
    • (2003) Microbes Infect , vol.5 , pp. 1082-1095
    • Daugelat, S.1    Kowall, J.2    Mattow, J.3    Bumann, D.4    Winter, R.5    Hurwitz, R.6    Kaufmann, S.H.7
  • 19
    • 33645236362 scopus 로고    scopus 로고
    • A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
    • Deb, C., J. Daniel, T. D. Sirakova, B. Abomoelak, V. S. Dubey, and P. E. Kolattukudy. 2006. A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J. Biol. Chem. 281:3866-3875.
    • (2006) J. Biol. Chem , vol.281 , pp. 3866-3875
    • Deb, C.1    Daniel, J.2    Sirakova, T.D.3    Abomoelak, B.4    Dubey, V.S.5    Kolattukudy, P.E.6
  • 20
    • 0034872325 scopus 로고    scopus 로고
    • Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis
    • Delogu, G., and M. J. Brennan. 2001. Comparative immune response to PE and PE_PGRS antigens of Mycobacterium tuberculosis. Infect. Immun. 69:5606-5611.
    • (2001) Infect. Immun , vol.69 , pp. 5606-5611
    • Delogu, G.1    Brennan, M.J.2
  • 21
    • 2442515282 scopus 로고    scopus 로고
    • Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure
    • Delogu, G., C. Pusceddu, A. Bua, G. Fadda, M. J. Brennan, and S. Zanetti. 2004. Rv1818c-encoded PE_PGRS protein of Mycobacterium tuberculosis is surface exposed and influences bacterial cell structure. Mol. Microbiol. 52:725-733.
    • (2004) Mol. Microbiol , vol.52 , pp. 725-733
    • Delogu, G.1    Pusceddu, C.2    Bua, A.3    Fadda, G.4    Brennan, M.J.5    Zanetti, S.6
  • 22
    • 0036774641 scopus 로고    scopus 로고
    • Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum
    • Garton, N. J., H. Christensen, D. E. Minnikin, R. A. Adegbola, and M. R. Barer. 2002. Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum. Microbiology 148:2951-2958.
    • (2002) Microbiology , vol.148 , pp. 2951-2958
    • Garton, N.J.1    Christensen, H.2    Minnikin, D.E.3    Adegbola, R.A.4    Barer, M.R.5
  • 23
    • 33751323180 scopus 로고    scopus 로고
    • Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
    • Gey van Pittius, N. C., S. L. Sampson, H. Lee, Y. Kim, P. D. van Helden, and R. M. Warren. 2006. Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 6:95.
    • (2006) BMC Evol. Biol , vol.6 , pp. 95
    • Gey van Pittius, N.C.1    Sampson, S.L.2    Lee, H.3    Kim, Y.4    van Helden, P.D.5    Warren, R.M.6
  • 24
    • 0024393520 scopus 로고
    • Changes in phospholipid fatty acid composition and triacylglycerol content in mouse tissues after infection with bacille Calmette-Guerin
    • Jackson, S. K., J. M. Stark, S. Taylor, and J. L. Harwood. 1989. Changes in phospholipid fatty acid composition and triacylglycerol content in mouse tissues after infection with bacille Calmette-Guerin. Br. J. Exp. Pathol. 70:435-441.
    • (1989) Br. J. Exp. Pathol , vol.70 , pp. 435-441
    • Jackson, S.K.1    Stark, J.M.2    Taylor, S.3    Harwood, J.L.4
  • 26
    • 20444418140 scopus 로고    scopus 로고
    • Expression, immunochemical characterization and localization of the Mycobacterium tuberculosis protein p27
    • Le Moigne, V., G. Robreau, C. Borot, J. L. Guesdon, and W. Mahana. 2005. Expression, immunochemical characterization and localization of the Mycobacterium tuberculosis protein p27. Tuberculosis (Edinburgh) 85:213-219.
    • (2005) Tuberculosis (Edinburgh) , vol.85 , pp. 213-219
    • Le Moigne, V.1    Robreau, G.2    Borot, C.3    Guesdon, J.L.4    Mahana, W.5
  • 27
    • 15944409915 scopus 로고    scopus 로고
    • A Mycobacterium avium PPE gene is associated with the ability of the bacterium to grow in macrophages and virulence in mice
    • Li, Y., E. Miltner, M. Wu, M. Petrofsky, and L. E. Bermudez. 2005. A Mycobacterium avium PPE gene is associated with the ability of the bacterium to grow in macrophages and virulence in mice. Cell. Microbiol. 7:539-548.
    • (2005) Cell. Microbiol , vol.7 , pp. 539-548
    • Li, Y.1    Miltner, E.2    Wu, M.3    Petrofsky, M.4    Bermudez, L.E.5
  • 28
    • 20944450448 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
    • Munoz-Elias, E. J., and J. D. McKinney. 2005. Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence. Nat. Med. 11:638-644.
    • (2005) Nat. Med , vol.11 , pp. 638-644
    • Munoz-Elias, E.J.1    McKinney, J.D.2
  • 29
    • 0031880495 scopus 로고    scopus 로고
    • Ethane-freezing/methanol-fixation of cell monolayers: A procedure for improved preservation of structure and antigenicity for light and electron microscopies
    • Neuhaus, E. M., H. Horstmann, W. Almers, M. Maniak, and T. Soldati. 1998. Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies. J. Struct. Biol. 121:326-342.
    • (1998) J. Struct. Biol , vol.121 , pp. 326-342
    • Neuhaus, E.M.1    Horstmann, H.2    Almers, W.3    Maniak, M.4    Soldati, T.5
  • 30
    • 0242349675 scopus 로고    scopus 로고
    • PPE protein (Rv3873) from DNA segment RD1 of Mycobacterium tuberculosis: Strong recognition of both specific T-cell epitopes and epitopes conserved within the PPE family
    • Okkels, L. M., I. Brock, F. Follmann, E. M. Agger, S. M. Arend, T. H. Ottenhoff, F. Oftung, I. Rosenkrands, and P. Andersen. 2003. PPE protein (Rv3873) from DNA segment RD1 of Mycobacterium tuberculosis: strong recognition of both specific T-cell epitopes and epitopes conserved within the PPE family. Infect. Immun. 71:6116-6123.
    • (2003) Infect. Immun , vol.71 , pp. 6116-6123
    • Okkels, L.M.1    Brock, I.2    Follmann, F.3    Agger, E.M.4    Arend, S.M.5    Ottenhoff, T.H.6    Oftung, F.7    Rosenkrands, I.8    Andersen, P.9
  • 32
    • 0030070034 scopus 로고    scopus 로고
    • Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species
    • Ortalo-Magne, A., A. Lemassu, M. A. Laneelle, F. Bardou, G. Silve, P. Gounon, G. Marchal, and M. Daffe. 1996. Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species. J. Bacteriol. 178:456-461.
    • (1996) J. Bacteriol , vol.178 , pp. 456-461
    • Ortalo-Magne, A.1    Lemassu, A.2    Laneelle, M.A.3    Bardou, F.4    Silve, G.5    Gounon, P.6    Marchal, G.7    Daffe, M.8
  • 33
    • 33746632536 scopus 로고    scopus 로고
    • Identification of antigenic components of Staphylococcus epidermidis expressed during human infection
    • Pourmand, M. R., S. R. Clarke, R. F. Schuman, J. J. Mond, and S. J. Foster. 2006. Identification of antigenic components of Staphylococcus epidermidis expressed during human infection. Infect. Immun. 74:4644-4654.
    • (2006) Infect. Immun , vol.74 , pp. 4644-4654
    • Pourmand, M.R.1    Clarke, S.R.2    Schuman, R.F.3    Mond, J.J.4    Foster, S.J.5
  • 34
    • 0034717008 scopus 로고    scopus 로고
    • Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family
    • Ramakrishnan, L., N. A. Federspiel, and S. Falkow. 2000. Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science 288:1436-1439.
    • (2000) Science , vol.288 , pp. 1436-1439
    • Ramakrishnan, L.1    Federspiel, N.A.2    Falkow, S.3
  • 36
    • 0043192504 scopus 로고    scopus 로고
    • Phagosomes, fatty acids and tuberculosis
    • Russell, D. G. 2003. Phagosomes, fatty acids and tuberculosis. Nat. Cell Biol. 5:776-778.
    • (2003) Nat. Cell Biol , vol.5 , pp. 776-778
    • Russell, D.G.1
  • 38
    • 0032457522 scopus 로고    scopus 로고
    • Expression of a gene for a porin-like protein of the OmpA family from Mycobacterium tuberculosis H37Rv
    • Senaratne, R. H., H. Mobasheri, K. G. Papavinasasundaram, P. Jenner, E. J. Lea, and P. Draper. 1998. Expression of a gene for a porin-like protein of the OmpA family from Mycobacterium tuberculosis H37Rv. J. Bacteriol. 180:3541-3547.
    • (1998) J. Bacteriol , vol.180 , pp. 3541-3547
    • Senaratne, R.H.1    Mobasheri, H.2    Papavinasasundaram, K.G.3    Jenner, P.4    Lea, E.J.5    Draper, P.6
  • 39
    • 33947369443 scopus 로고    scopus 로고
    • Macrophage-specific Mycobacterium tuberculosis genes: Identification by green fluorescent protein and kanamycin resistance selection
    • Srivastava, V., C. Rouanet, R. Srivastava, B. Ramalingam, C. Locht, and B. S. Srivastava. 2007. Macrophage-specific Mycobacterium tuberculosis genes: identification by green fluorescent protein and kanamycin resistance selection. Microbiology 153:659-666.
    • (2007) Microbiology , vol.153 , pp. 659-666
    • Srivastava, V.1    Rouanet, C.2    Srivastava, R.3    Ramalingam, B.4    Locht, C.5    Srivastava, B.S.6
  • 41
    • 33744459472 scopus 로고    scopus 로고
    • Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis
    • Strong, M., M. R. Sawaya, S. Wang, M. Phillips, D. Cascio, and D. Eisenberg. 2006. Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 103:8060-8065.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8060-8065
    • Strong, M.1    Sawaya, M.R.2    Wang, S.3    Phillips, M.4    Cascio, D.5    Eisenberg, D.6
  • 42
    • 32344444893 scopus 로고    scopus 로고
    • Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: Evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other
    • Tundup, S., Y. Akhter, D. Thiagarajan, and S. E. Hasnain. 2006. Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other. FEBS Lett. 580:1285-1293.
    • (2006) FEBS Lett , vol.580 , pp. 1285-1293
    • Tundup, S.1    Akhter, Y.2    Thiagarajan, D.3    Hasnain, S.E.4
  • 44
    • 33846283740 scopus 로고    scopus 로고
    • PPE protein (Rv3425) from DNA segment RD11 of Mycobacterium tuberculosis: A potential B-cell antigen used for serological diagnosis to distinguish vaccinated controls from tuberculosis patients
    • Zhang, H., J. Wang, J. Lei, M. Zhang, Y. Yang, Y. Chen, and H. Wang. 2007. PPE protein (Rv3425) from DNA segment RD11 of Mycobacterium tuberculosis: a potential B-cell antigen used for serological diagnosis to distinguish vaccinated controls from tuberculosis patients. Clin. Microbiol. Infect. 13:139-145.
    • (2007) Clin. Microbiol. Infect , vol.13 , pp. 139-145
    • Zhang, H.1    Wang, J.2    Lei, J.3    Zhang, M.4    Yang, Y.5    Chen, Y.6    Wang, H.7
  • 45
    • 20444381377 scopus 로고    scopus 로고
    • Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis
    • Zhang, M., J. D. Wang, Z. F. Li, J. Xie, Y. P. Yang, Y. Zhong, and H. H. Wang. 2005. Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis. Protein Expr. Purif. 42:59-66.
    • (2005) Protein Expr. Purif , vol.42 , pp. 59-66
    • Zhang, M.1    Wang, J.D.2    Li, Z.F.3    Xie, J.4    Yang, Y.P.5    Zhong, Y.6    Wang, H.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.