Protective effect of dieckol isolated from Ecklonia cava against ethanol caused damage in vitro and in zebrafish model

Environmental Toxicology and Pharmacology

Volumn 36, Issue 3, 2013, Pages 1217-1226

  Kang, Min Cheol ^a   Kim, Kil Nam ^b   Kang, Sung Myung ^a   Yang, Xiudong ^a   Kim, Eun A ^a   Song, Choon Bok ^a   Nah, Jae Woon ^c   Jang, Mi Kyeong ^c   Lee, Jung Suck ^a   Jung, Won Kyo ^d   Jeon, You Jin ^a,e  

^a Jeju National University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

^c Sunchon National University   (South Korea)

^d Pukyong National University   (South Korea)

^e Aqua Green Technology Co Ltd   (South Korea)

Author keywords

Alcohol; Dieckol; Ecklonia cava; Hepato protective effect; Phlorotannin; Zebrafish

Indexed keywords

ALCOHOL; CASPASE 3; DIECKOL; ECKOL; LIVER PROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHLOROGLUCINOL; PROTEIN BAX; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; TANNIN DERIVATIVE; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; ECKLONIA CAVA; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; ZEBRA FISH;

ALCOHOL; DIECKOL; ECKLONIA CAVA; HEPATO-PROTECTIVE EFFECT; PHLOROTANNIN; ZEBRAFISH;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BENZIMIDAZOLES; BENZOFURANS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMBRYO, NONMAMMALIAN; ETHANOL; FLUORESCENT DYES; IMAGE PROCESSING, COMPUTER-ASSISTED; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; PHAEOPHYTA; REACTIVE OXYGEN SPECIES; SEAWEED; ZEBRAFISH;

EID: 84887160806     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.09.018     Document Type: Article

References (32)

1. Adachi M., Higuchi H., Miura S., Azuma T., Inokuchi S., Saito H., Kato S., Ishii H. Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytes. Am. J. Physiol. 2004, 287:G695-G705.
2. 2-mediated DNA damage. Eur. Food Res. Technol. 2007, 226:71-79.
3. Alshawsh M.A., Abdulla A.A., Ismail S., Amin Z.A. Hepatoprotective effects of Orthosiphon stamineus extract on thioacetamide-induced liver cirrhosis in rats. Evid. Based Complement. Altern. Med. 2011, 10.1155/2011/103039.
4. Bondy S.C. Reactive oxygen species: relation to aging and neurotoxic damage. Neurotoxicology 1992, 13:87-100.
5. Chen Y.H., Wang M.F., Liao J.W., Chang S.P., Hu M.L. Beneficial effects of nicotinamide on alcohol-induced liver injury in senescence-accelerated mice. BioFactors 2008, 34(2):97-107.
6. Choi E.Y., Hwang H.J., Nam T.J. Protective effect of a polysaccharide from Hizikia fusiformis against ethanol-induced cytotoxicity in IEC-6 cells. Toxicol. In Vitro 2010, 24:79-84.
7. Cohen J.I., Roychowdhury S., DiBello P.M., Jacobsen D.W., Nagy L.E. Exogenous thioredoxin prevents ethanol induced oxidative damage and apoptosis in mouse liver. Hepatology 2009, 49:1709-1717.
8. Driver W., Solnica-Krezel L., Schier A.F., Neuhauss S.C., Malicki J., Stemple D.L., Stainier D.Y., Zwartkruis F., Abdelilah S., Rangini Z., Belak J., Boqqs C. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 1996, 123:37-46.
9. Heo S.J., Park E.J., Lee K.W., Jeon Y.J. Antioxidant activities of enzymatic extracts from brown seaweed. Bioresour. Technol. 2005, 96(14):1613-1623.
10. Heo S.J., Yoon W.J., Kim K.N., Ahn G.N., Kang S.M., Kang D.H., Affan A., Oh C., Jung W.K., Jeon Y.J. Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food Chem. Toxicol. 2010, 48:2045-2051.
11. Heo S.J., Ko S.C., Cha S.H., Kang.F D.H., Park H.S., Choi Y.U., Kim D., Jung W.K., Jeon Y.J. Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol. In Vitro 2009, 23:1123-1130.
12. Husain K., Scott B.R., Reddy S.K., Somani S.M. Chronic ethanol and nicotine interaction on rat tissue antioxidant defense system. Alcohol 2001, 25:89-97.
13. Katz G.G., Shear N.H., Malkiewicz I.M., Valentino K., Neumann M.G. Signaling for ethanol-induced apoptosis ad repair in vitro. Clin. Biochem. 2001, 34(3):219-227.
14. Kang K., Hwang H.J., Hong D.H., Park Y., Kim S.H., Lee B.H., Shin H.C. Antioxidant and anti-inflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explants culture. Res. Commun. Mol. Pathol. Pharmacol. 2004, 115-116:77-95.
15. Kang M.C., Ahn G., Yang X., Kim K.N., Kang S.M., Lee S.H., Ko S.C., Ko J.Y., Kim D., Kim Y.T., Jee Y., Park S.J., Jeon Y.J. Hepatoprotective effect of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. Food Chem. Toxicol. 2012, 50:1986-1991.
16. Kang M.C., Cha S.H., Wijesinghe W.A.J.P., Kang S.M., Lee S.H., Kim E., Song C.B., Jeon Y.J. Protective effect of marine algae phlorotanins against AAPH-induced oxidative stress in zebrafish embryo. Food Chem. 2013, 138:950-955.
17. Khanal T., Choi J.H., Hwang Y.P., Chung Y.C., Jeong H.G. Saponins isolated from the rood of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice. Food Chem. Toxicol. 2009, 47:530-535.
18. Krithika R., Verma R.J., Shrivastav P.S., Suguna L. Phyllanthin of standardized Phyllanthus amarus extract attenuates liver oxidative stress in mice and exerts cytoprotective activity on human hepatoma cell line. J. Clin. Exp. Hepatol. 2011, 1(2):57-67.
19. Kuda T., Tsunekawa M., Goto H., Araki Y. Antioxidant properties of four edible algae harvested in the Noto Peninsula Japan. J. Food Compos. Anal. 2005, 18:625-633.
20. Li Y., Qian Z.J., Ryu B.M., Lee S.H., Kim M.M., Kim S.K. Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava. Bioorg. Med. Chem. 2009, 17:1963-1973.
21. Lizard G., Fournel S., Genestier L., Dhedin N., Chaput C., Flacher M., Mutin M., Panaye G., Revillard J.P. Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis. Cytometry 1995, 21(3):275-283.
22. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65(1-2):55-63.
23. Nagayama K., Iwamura Y., Shibata T., Hirayama I., Nakamura T. Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome. J. Antimicrob. Chemother. 2002, 50(6):889-893.
24. Natori S., Higuchi H., Contreras P., Gores G.J. The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injury. Liver Transpl. 2003, 9(3):278-284.
25. Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 1991, 3(139):271-279.
26. Pandanaboina S.C., Kondeti S.R., Rajbanshi S.L., Kunala P.N., Pandanaboina S., Pandanaboina M.M., Wudayagiri R. Alterations in antioxidant enzyme activities and oxidative damage in alcoholic rat tissues: protective role of Thespesia populnea. Food Chem. 2012, 132(1):150-159.
27. Rosenkranz A.R., Schmaldienst S., Stuhlmeier K.M., Chen W., Knapp W., Zlabinger G.J. Amicroplate assay for the detection of oxidative product using 2',7'-dichlorofluorescin-diacetate. J. Immunol. Methods 1992, 156(1):39-45.
28. Seki S., Kitada T., Yamada Y., Sakaguchi H., Nakatani K., Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases. J. Hepatol. 2002, 37:56-62.
29. Shibata T., Ishimaru K., Kawaguchi S., Yoshikawa H., Hama Y. Antioxidant activities of phlorotannins isolated from Japanese Laminariaceae. J. Appl. Phycol. 2008, 20:705-711.
30. Wang S.Y., Gong Y.S., Zhou J.J. Chromatographic isolation and characterization of a novel peroxidase from large lima legumes. J. Food Sci. 2008, 74(3):193-198.
31. Wu D., Cederbaum A.I. Ethanol cytotoxicity to a transfected HepG2 cell lines expressing human cytochrome P-4502E1. Alcohol. Clin. Exp. Res. 1999, 23:67-76.
32. Zima T., Fialova L., Mestek O., Janebova M., Crkovska J., Malbohan I., Stanisav S., Mikulikova L., Popov P. Oxidative stress, metabolism of ethanol and alcohol-related disease. J. Biomed. Sci. 2001, 8:59-70.