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Volumn 132, Issue 5, 2013, Pages

Hypospadias and residential proximity to pesticide applications

Author keywords

Birth defects; Endocrine disruptors; Environment; Hypospadias; Pesticides

Indexed keywords

ALDICARB; ALUMINUM PHOSPHIDE; BENFLURALIN; BENOMYL; BIFENTHRIN; CACODYLIC ACID; CARBOFURAN; COPPER SULFATE; DIMETHOATE; DIMETHYLAMINE; DIMPYLATE; DITHIOCARBAMIC ACID; ENDOSULFAN; METHIDATHION; ORGANOPHOSPHATE; ORGANOTIN COMPOUND; PARATHION METHYL; PESTICIDE; PHORATE; PHOSMET; POLYOXYETHYLENE; SORBITOL; STREPTOMYCIN; TRIFLURALIN;

EID: 84887110376     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2013-1429     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 0032945377 scopus 로고    scopus 로고
    • International trends in rates of hypospadias and cryptorchidism
    • Paulozzi LJ. International trends in rates of hypospadias and cryptorchidism. Environ Health Perspect. 1999;107(4):297-302. (Pubitemid 29231633)
    • (1999) Environmental Health Perspectives , vol.107 , Issue.4 , pp. 297-302
    • Paulozzi, L.J.1
  • 2
    • 0030862239 scopus 로고    scopus 로고
    • Hypospadias trends in two US surveillance systems
    • DOI 10.1542/peds.100.5.831
    • Paulozzi LJ, Erickson JD, Jackson RJ. Hypospadias trends in two US surveillance systems. Pediatrics. 1997;100(5):831-834. (Pubitemid 27463319)
    • (1997) Pediatrics , vol.100 , Issue.5 , pp. 831-834
    • Paulozzi, L.J.1    Erickson, J.D.2    Jackson, R.J.3
  • 4
    • 0242349769 scopus 로고    scopus 로고
    • Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors
    • DOI 10.1002/bdra.10084
    • Manson JM, Carr MC. Molecular epidemiology of hypospadias: review of genetic and environmental risk factors. Birth Defects Res A Clin Mol Teratol. 2003;67(10):825-836. (Pubitemid 37337565)
    • (2003) Birth Defects Research Part A - Clinical and Molecular Teratology , vol.67 , Issue.10 , pp. 825-836
    • Manson, J.M.1    Carr, M.C.2
  • 5
    • 84863768735 scopus 로고    scopus 로고
    • Environmental and genetic contributors to hypospadias: A review of the epidemiologic evidence
    • Carmichael SL, Shaw GM, Lammer EJ. Environmental and genetic contributors to hypospadias: A review of the epidemiologic evidence. Birth Defects Res A Clin Mol Teratol. 2012;94(7):499-510.
    • (2012) Birth Defects Res a Clin Mol Teratol , vol.94 , Issue.7 , pp. 499-510
    • Carmichael, S.L.1    Shaw, G.M.2    Lammer, E.J.3
  • 6
    • 14344265890 scopus 로고    scopus 로고
    • Hypospadias: Psychosocial, sexual, and reproductive consequences in adult life
    • Mieusset R, Soulié M. Hypospadias: psychosocial, sexual, and reproductive consequences in adult life. J Androl. 2005;26 (2):163-168. (Pubitemid 40293697)
    • (2005) Journal of Andrology , vol.26 , Issue.2 , pp. 163-168
    • Mieusset, R.1    Soulie, M.2
  • 7
    • 0023892907 scopus 로고
    • Fertility in patients with hypospadias
    • Jugenburg I, Kipikasa A. Fertility in patients with hypospadias. Acta Chir Plast. 1988;30 (2):86-93.
    • (1988) Acta Chir Plast , vol.30 , Issue.2 , pp. 86-93
    • Jugenburg, I.1    Kipikasa, A.2
  • 8
    • 2342512854 scopus 로고    scopus 로고
    • Toxicantinduced hypospadias in the male rat
    • Gray LE Jr, Ostby J, Furr J, et al. Toxicantinduced hypospadias in the male rat. Adv Exp Med Biol. 2004;545:217-241.
    • (2004) Adv Exp Med Biol , vol.545 , pp. 217-241
    • Gray Jr., L.E.1    Ostby, J.2    Furr, J.3
  • 9
    • 0343962125 scopus 로고    scopus 로고
    • Environmental antiandrogens: Low doses of the fungicide vinclozolin alter sexual differentiation of the male rat
    • Gray LE Jr, Ostby J, Monosson E, Kelce WR. Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat. Toxicol Ind Health. 1999;15(1-2):48-64. (Pubitemid 30484117)
    • (1999) Toxicology and Industrial Health , vol.15 , Issue.1-2 , pp. 48-64
    • Gray Jr., L.E.1    Ostby, J.2    Monosson, E.3    Kelce, W.R.4
  • 10
    • 18844429502 scopus 로고    scopus 로고
    • Late gestational exposure to the fungicide prochloraz delays the onset of parturition and causes reproductive malformations in male but not female rat offspring
    • DOI 10.1095/biolreprod.104.031385
    • Noriega NC, Ostby J, Lambright C, Wilson VS, Gray LE Jr. Late gestational exposure to the fungicide prochloraz delays the onset of parturition and causes reproductive malformations in male but not female rat offspring. Biol Reprod. 2005;72(6):1324- 1335. (Pubitemid 40696075)
    • (2005) Biology of Reproduction , vol.72 , Issue.6 , pp. 1324-1335
    • Noriega, N.C.1    Ostby, J.2    Lambright, C.3    Wilson, V.S.4    Gray Jr., L.E.5
  • 11
    • 1542351641 scopus 로고    scopus 로고
    • Induction of hypospadias in a murine model by maternal exposure to synthetic estrogens
    • DOI 10.1016/S0013-9351(03)00085-9, PII S0013935103000859
    • Kim KS, Torres CR Jr, Yucel S, Raimondo K, Cunha GR, Baskin LS. Induction of hypospadias in a murine model by maternal exposure to synthetic estrogens. Environ Res. 2004;94(3):267-275. (Pubitemid 38328680)
    • (2004) Environmental Research , vol.94 , Issue.3 , pp. 267-275
    • Kim, K.S.1    Torres Jr., C.R.2    Yucel, S.3    Raimondo, K.4    Cunha, G.R.5    Baskin, L.S.6
  • 13
    • 77956898039 scopus 로고    scopus 로고
    • Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infants
    • Nassar N, Abeywardana P, Barker A, Bower C. Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infants. Occup Environ Med. 2010;67(9):585-589.
    • (2010) Occup Environ Med , vol.67 , Issue.9 , pp. 585-589
    • Nassar, N.1    Abeywardana, P.2    Barker, A.3    Bower, C.4
  • 14
    • 78651362864 scopus 로고    scopus 로고
    • Parental occupational exposure to endocrine disrupting chemicals and male genital malformations: A study in the Danish National Birth Cohort study
    • Morales-Suárez-Varela MM, Toft GV, Jensen MS, et al. Parental occupational exposure to endocrine disrupting chemicals and male genital malformations: A study in the Danish National Birth Cohort study. Environ Health. 2011;10(1):3.
    • (2011) Environ Health , vol.10 , Issue.1 , pp. 3
    • Morales-Suárez-varela, M.M.1    Toft, G.V.2    Jensen, M.S.3
  • 15
    • 80855147845 scopus 로고    scopus 로고
    • Maternal occupational pesticide exposure and risk of hypospadias in the national birth defects prevention study
    • Rocheleau CM, Romitti PA, Sanderson WT, et al. Maternal occupational pesticide exposure and risk of hypospadias in the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol. 2011;91(11): 927-936.
    • (2011) Birth Defects Res a Clin Mol Teratol , vol.91 , Issue.11 , pp. 927-936
    • Rocheleau, C.M.1    Romitti, P.A.2    Sanderson, W.T.3
  • 16
    • 14744273497 scopus 로고    scopus 로고
    • Organochlorine pesticides and male genital anomalies in the child health and development studies
    • DOI 10.1289/ehp.7382
    • Bhatia R, Shiau R, Petreas M, Weintraub JM, Farhang L, Eskenazi B. Organochlorine pesticides and male genital anomalies in the child health and development studies. Environ Health Perspect. 2005;113(2):220- 224. (Pubitemid 40326334)
    • (2005) Environmental Health Perspectives , vol.113 , Issue.2 , pp. 220-224
    • Bhatia, R.1    Shiau, R.2    Petreas, M.3    Weintraub, J.M.4    Farhang, L.5    Eskenazi, B.6
  • 18
    • 0037083090 scopus 로고    scopus 로고
    • Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring
    • DOI 10.1093/aje/155.4.313
    • Longnecker MP, Klebanoff MA, Brock JW, et al. Maternal serum level of 1, 1-dichloro- 2, 2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring. Am J Epidemiol. 2002;155(4):313-322. (Pubitemid 34132049)
    • (2002) American Journal of Epidemiology , vol.155 , Issue.4 , pp. 313-322
    • Longnecker, M.P.1    Klebanoff, M.A.2    Brock, J.W.3    Zhou, H.4    Gray, K.A.5    Needham, L.L.6    Wilcox, A.J.7
  • 19
    • 77950814705 scopus 로고    scopus 로고
    • Maternal exposures to endocrine disrupting chemicals and hypospadias in offspring
    • Giordano F, Abballe A, De Felip E, et al. Maternal exposures to endocrine disrupting chemicals and hypospadias in offspring. Birth Defects Res A Clin Mol Teratol. 2010;88(4):241-250.
    • (2010) Birth Defects Res a Clin Mol Teratol , vol.88 , Issue.4 , pp. 241-250
    • Giordano, F.1    Abballe, A.2    De Felip, E.3
  • 20
    • 77953807730 scopus 로고    scopus 로고
    • Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples
    • Carmichael SL, Herring AH, Sjödin A, et al. Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples. Chemosphere. 2010;80(6): 641-646.
    • (2010) Chemosphere , vol.80 , Issue.6 , pp. 641-646
    • Carmichael, S.L.1    Herring, A.H.2    Sjödin, A.3
  • 21
    • 84857692512 scopus 로고    scopus 로고
    • Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys
    • Trabert B, Longnecker MP, Brock JW, Klebanoff MA, McGlynn KA. Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys. Environ Health Perspect. 2012;120(3):478-482.
    • (2012) Environ Health Perspect , vol.120 , Issue.3 , pp. 478-482
    • Trabert, B.1    Longnecker, M.P.2    Brock, J.W.3    Klebanoff, M.A.4    McGlynn, K.A.5
  • 23
    • 0026005827 scopus 로고
    • Birth defects monitoring in California: A resource for epidemiological research
    • Croen LA, Shaw GM, Jensvold NG, Harris JA. Birth defects monitoring in California: A resource for epidemiological research. Paediatr Perinat Epidemiol. 1991;5(4):423- 427.
    • (1991) Paediatr Perinat Epidemiol , vol.5 , Issue.4 , pp. 423-427
    • Croen, L.A.1    Shaw, G.M.2    Jensvold, N.G.3    Harris, J.A.4
  • 24
    • 1542472955 scopus 로고    scopus 로고
    • Hypospadias in California: Trends and descriptive epidemiology
    • DOI 10.1097/01.ede.0000091603.43531.d0
    • Carmichael SL, Shaw GM, Nelson V, Selvin S, Torfs CP, Curry CJ. Hypospadias: Trends and descriptive epidemiology in a California population. Epidemiology. 2003;14(6):701- 706. (Pubitemid 40417018)
    • (2003) Epidemiology , vol.14 , Issue.6 , pp. 701-706
    • Carmichael, S.L.1    Shaw, G.M.2    Nelson, V.3    Selvin, S.4    Torfs, C.P.5    Curry, C.J.6
  • 26
    • 84887035330 scopus 로고    scopus 로고
    • Available at:, Accessed May 1, 2013
    • California Environmental Health Tracking Program. Geocoding Service. 2012. Available at: http://cehtp.org/geocoding Accessed May 1, 2013.
    • (2012) Geocoding Service
  • 27
    • 0142029013 scopus 로고    scopus 로고
    • Historical pesticide exposure in California using pesticide use reports and land-use surveys: An assessment of misclassification error and bias
    • Rull RP, Ritz B. Historical pesticide exposure in California using pesticide use reports and land-use surveys: An assessment of misclassification error and bias. Environ Health Perspect. 2003;111(13):1582-1589. (Pubitemid 37265967)
    • (2003) Environmental Health Perspectives , vol.111 , Issue.13 , pp. 1582-1589
    • Rull, R.P.1    Ritz, B.2
  • 28
    • 84887108272 scopus 로고    scopus 로고
    • Available at:, Accessed May 1, 2013
    • California Environmental Health Tracking Program. Agricultural Pesticide Mapping Tool. 2012. Available at: http://cehtp.org/p/tools-pesticide. Accessed May 1, 2013.
    • (2012) Agricultural Pesticide Mapping Tool
  • 29
    • 35448966195 scopus 로고    scopus 로고
    • Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley
    • DOI 10.1289/ehp.10168
    • Roberts EM, English PB, Grether JK, Windham GC, Somberg L, Wolff C. Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley. Environ Health Perspect. 2007;115(10):1482-1489. (Pubitemid 47618092)
    • (2007) Environmental Health Perspectives , vol.115 , Issue.10 , pp. 1482-1489
    • Roberts, E.M.1    English, P.B.2    Grether, J.K.3    Windham, G.C.4    Somberg, L.5    Wolff, C.6
  • 31
    • 85039765046 scopus 로고    scopus 로고
    • Available at, Accessed May 1, 2013
    • Pesticide Chemical Search EPA. Available at: www.epa.gov/pesticides/ chemicalsearch. Accessed May 1, 2013.
    • Pesticide Chemical Search EPA
  • 32
    • 84887121793 scopus 로고    scopus 로고
    • California Office of Environmental Health Hazard Assessment. Available at:, Accessed May 1, 2013
    • California Office of Environmental Health Hazard Assessment. Proposition 65. 2012. Available at: www.oehha.ca.gov/prop65.html Accessed May 1, 2013.
    • (2012) Proposition 65
  • 37
    • 0031782184 scopus 로고    scopus 로고
    • Effects of the pesticides carbofuran, chlorpyrifos, dimethoate, lindane, triallate, trifluralin, 2,4-D, and pentachlorophenol on the metabolic endocrine and reproductive endocrine system in ewes
    • Rawlings NC, Cook SJ, Waldbillig D. Effects of the pesticides carbofuran, chlorpyrifos, dimethoate, lindane, triallate, trifluralin, 2, 4-D, and pentachlorophenol on the metabolic endocrine and reproductive endocrine system in ewes. J Toxicol Environ Health A. 1998;54(1):21-36. (Pubitemid 28427194)
    • (1998) Journal of Toxicology and Environmental Health - Part A , vol.54 , Issue.1 , pp. 21-36
    • Rawlings, N.C.1    Cook, S.J.2    Waldbillig, D.3
  • 38
    • 64549108813 scopus 로고    scopus 로고
    • Endocrine disrupting effects of herbicides and pentachlorophenol: In vitro and in vivo evidence
    • Orton F, Lutz I, Kloas W, Routledge EJ. Endocrine disrupting effects of herbicides and pentachlorophenol: in vitro and in vivo evidence. Environ Sci Technol. 2009;43(6): 2144-2150.
    • (2009) Environ Sci Technol , vol.43 , Issue.6 , pp. 2144-2150
    • Orton, F.1    Lutz, I.2    Kloas, W.3    Routledge, E.J.4
  • 40
    • 0031677817 scopus 로고    scopus 로고
    • Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents
    • Hurley PM. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents. Environ Health Perspect. 1998;106(8):437-445. (Pubitemid 28470158)
    • (1998) Environmental Health Perspectives , vol.106 , Issue.8 , pp. 437-445
    • Hurley, P.M.1    Hill, R.N.2    Whiting, R.J.3
  • 41
    • 10044236969 scopus 로고    scopus 로고
    • Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells
    • Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect. 2004;112(5):524-531. (Pubitemid 38500039)
    • (2004) Environmental Health Perspectives , vol.112 , Issue.5 , pp. 524-531
    • Kojima, H.1    Katsura, E.2    Takeuchi, S.3    Niiyama, K.4    Kobayashi, K.5
  • 43
    • 0021967595 scopus 로고
    • Organophosphorus insecticide induced decrease in plasma luteinizing hormone concentration in white-footed mice
    • DOI 10.1016/0378-4274(85)90141-9
    • Rattner BA, Michael SD. Organophosphorus insecticide induced decrease in plasma luteinizing hormone concentration in whitefooted mice. Toxicol Lett. 1985;24(1):65-69. (Pubitemid 15172607)
    • (1985) Toxicology Letters , vol.24 , Issue.1 , pp. 65-69
    • Rattner, B.A.1    Michael, S.D.2
  • 44
    • 0030022687 scopus 로고    scopus 로고
    • Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicals
    • DOI 10.1897/1551-5028(1996)015<0194:IOTGIR>2.3.CO;2
    • Jobling S, Sheahan D, Osborne JA, Matthiessen P, Sumpter JP. Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicals. Environ Toxicol Chem. 1996;15(2):194-202. (Pubitemid 26060518)
    • (1996) Environmental Toxicology and Chemistry , vol.15 , Issue.2 , pp. 194-202
    • Jobling, S.1    Sheahan, D.2    Osborne, J.A.3    Matthiessen, P.4    Sumpter, J.P.5
  • 45
    • 0036908857 scopus 로고    scopus 로고
    • Community exposures to airborne agricultural pesticides in California: Ranking of inhalation risks
    • Lee S, McLaughlin R, Harnly M, Gunier R, Kreutzer R. Community exposures to airborne agricultural pesticides in California: ranking of inhalation risks. Environ Health Perspect. 2002;110(12):1175-1184. (Pubitemid 36024300)
    • (2002) Environmental Health Perspectives , vol.110 , Issue.12 , pp. 1175-1184
    • Lee, S.1    McLaughlin, R.2    Harnly, M.3    Gunier, R.4    Kreutzer, R.5
  • 46
    • 33745618530 scopus 로고    scopus 로고
    • Secondhand pesticides: Airborne pesticide drift in California
    • San Francisco, CA: California Rural Legal Assistance Foundation, Pesticide Education Center, and Californians for Pesticide Reform. Available at, Accessed May 1, 2013
    • Kegley SE, Katten A, Moses M. Secondhand Pesticides: Airborne Pesticide Drift in California. Pesticide Action Network. San Francisco, CA: California Rural Legal Assistance Foundation, Pesticide Education Center, and Californians for Pesticide Reform. 2003. Available at: www.pesticideresearch.com/site/docs/ SecondhandPcides.pdf. Accessed May 1, 2013.
    • (2003) Pesticide Action Network
    • Kegley, S.E.1    Katten, A.2    Moses, M.3
  • 47
    • 0031424649 scopus 로고    scopus 로고
    • Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington State
    • Loewenherz C, Fenske RA, Simcox NJ, Bellamy G, Kalman D. Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington State. Environ Health Perspect. 1997;105(12):1344-1353. (Pubitemid 28066012)
    • (1997) Environmental Health Perspectives , vol.105 , Issue.12 , pp. 1344-1353
    • Loewenherz, C.1    Fenske, R.A.2    Simcox, N.J.3    Bellamy, G.4    Kalman, D.5
  • 48
    • 0029556405 scopus 로고
    • Pesticides in household dust and soil: Exposure pathways for children of agricultural families
    • Simcox NJ, Fenske RA, Wolz SA, Lee IC, Kalman DA. Pesticides in household dust and soil: Exposure pathways for children of agricultural families. Environ Health Perspect. 1995;103(12):1126-1134. (Pubitemid 26136951)
    • (1995) Environmental Health Perspectives , vol.103 , Issue.12 , pp. 1126-1134
    • Simcox, N.J.1    Fenske, R.A.2    Wolz, S.A.3    Lee, I.-C.4    Kalman, D.A.5
  • 49
    • 27744468993 scopus 로고    scopus 로고
    • Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers: An analysis of recent studies in Washington State
    • DOI 10.1289/ehp.8022
    • Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC. Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers: An analysis of recent studies in Washington State. Environ Health Perspect. 2005;113(11):1651- 1657. (Pubitemid 41614926)
    • (2005) Environmental Health Perspectives , vol.113 , Issue.11 , pp. 1651-1657
    • Fenske, R.A.1    Lu, C.2    Curl, C.L.3    Shirai, J.H.4    Kissel, J.C.5
  • 50
    • 0033637855 scopus 로고    scopus 로고
    • Pesticide exposure of children in an agricultural community: Evidence of household proximity to farmland and take home exposure pathways
    • Lu CF, Fenske RA, Simcox NJ, Kalman D. Pesticide exposure of children in an agricultural community: Evidence of household proximity to farmland and take home exposure pathways. Environ Res. 2000;84(3): 290-302.
    • (2000) Environ Res , vol.84 , Issue.3 , pp. 290-302
    • Lu, C.F.1    Fenske, R.A.2    Simcox, N.J.3    Kalman, D.4
  • 51
    • 67449132400 scopus 로고    scopus 로고
    • Endocrine-disrupting chemicals: An Endocrine Society scientific statement
    • e1226 CARMICHAEL
    • Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, et al. Endocrine-disrupting chemicals: An Endocrine Society scientific statement. Endocr Rev. 2009;30(4):293-342 e1226 CARMICHAEL.
    • (2009) Endocr Rev , vol.30 , Issue.4 , pp. 293-342
    • Diamanti-Kandarakis, E.1    Bourguignon, J.P.2    Giudice, L.C.3


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