Effects of the pesticides carbofuran, chlorpyrifos, dimethoate, lindane, triallate, trifluralin, 2,4-D, andpentachlorophenol on the metabolic endocrine and reproductive endocrine system in ewes

Journal of Toxicology and Environmental Health - Part A

Volumn 54, Issue 1, 1998, Pages 21-36

  Rawlings, N C ^a   Cook, S J ^a   Waldbillig, D ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOFURAN; CHLORPYRIFOS; DIMETHOATE; ESTRADIOL; GELATIN; HYDROCORTISONE; INSULIN; LINDANE; LUTEINIZING HORMONE; PENTACHLOROPHENOL; PESTICIDE; THYROXINE; TRIALLATE; TRIFLURALIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; CYST; ENDOCRINE SYSTEM; ESTRADIOL BLOOD LEVEL; FEMALE; HISTOPATHOLOGY; HYDROCORTISONE BLOOD LEVEL; INSULIN BLOOD LEVEL; LUTEINIZING HORMONE BLOOD LEVEL; NONHUMAN; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL;

AGRICULTURE; ANIMALS; CARBOFURAN; CHLORPYRIFOS; DIMETHOATE; ENDOCRINE SYSTEM; FEMALE; LINDANE; PENTACHLOROPHENOL; PESTICIDES; REPRODUCTION; SHEEP; THYROXINE; TRIALLATE; TRIFLURALIN;

ANIMALIA; OVIS;

EID: 0031782184     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/009841098159006     Document Type: Article

References (40)

1. Agrawal, D., Khanna, R. N., Anand, M., Gupta, G. S., and Ray, P. K. 1987. Lindane-induced changes in glucose and glutathione l evels in cats. Toxicol. Lett. 38:77-82.
2. Anand, M., Gulati, A., Gopal, K., Gupta, G. S., Khanna, R. N., Ray, P. K., and Chandra, S. V. 1990. Hypertension and myocarditis in rabbits exposed to hexachlorocyclohexane and endosulfan. Vet. Hum. Toxicol. 32:521-523.
3. Capen, C. C., and Martin, S. L. 1989. The thyroid gland. In Veterinary endocrinology and reproduction, eds. L. E. McDonald and M. H. Pineda, 4th ed., pp. 58-91. Philadelphia: Lea and Febiger.
4. Chadwick, R. W., Cooper, R. L., Chang, J., Rehnberg, G. L., and McElroy, W. K. 1988. Possible antiestrogenic activity of lindane in female rats. J. Biochem. Toxicol. 3:147-158.
5. Colborn, T., vom Saal, F. S., and Soto, A. M. 1993. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 101:378-384.
6. Cooper, R. L., Chadwick, R. W., Rehnberg, G. L., Goldman, J. M., Booth, K. C., Hein, J. F., and McElroy, W. K. 1989. Effect of lindane on hormonal control of reproductive function in the female rat. Toxicol. Appl. Pharmacol. 99:384-394.
7. Cranmer, J. S., Avery, D. L., Grady, R. R., and Kitay, J. I. 1978. Postnatal endocrine dysfunction resulting from prenatal exposure to carbofuran, diazinon or chlordane. J. Environ. Pathol. Toxicol. 2:357-369.
8. Currie, W. D., Medhamurthy, R. J., Cook, S. J., and Rawlings, N. C. 1993. Seasonal fluctuation in diurnal rhythms of luteinizing hormone secretion in ewes during the mid-luteal phase of the oestrous cycle. J. Reprod. Fertil. 97:71-74.
9. Ecobichon, D. J. 1991. Toxic effects of pesticides. In Cassarett and Doull's toxicology, eds. M. O. Amdur, J. Doull, and C. D. Klaassen, 4th ed., pp. 565-622. New York: Academic Press.
10. Exon, J. H., and Koller, L. D. 1982. Effects of transplacental exposure to chlorinated phenols. Environ. Health. Perspect. 46:137-140.
11. Goodman, R. L. 1994. Neuroendocrine control of the ovine oestrous cycle. In The physiology of reproduction, eds. E. Knobil and J. D. Neill, 2nd ed., pp. 659-710. New York: Raven Press.
12. Gorzinski, S. J., Kociba, R. J., Campbell, R. A., Smith, F. A., Nolan, R. J., and Eisenbrandt, D. L. 1987. Acute, pharmacokinetic and subchronic toxicological studies of 2,4-dichlorophenoxyacetic acid. Fundam. Appl. Toxicol. 9:423-435.
13. Gray, L. E. Jr., Ostby, J., Sigmon, R., Ferrell, J., Rehnberg, G., Linder, R., Cooper, R., Goldman, J., and Laskey, J. 1988. The development of a protocol to assess reproductive effects of toxicants in the rat. Reprod. Toxicol. 2:281-287.
14. Hayes, W. J., Jr., and Laws, E. R., Jr. 1991. Handbook of pesticide toxicology. San Diego, CA: Academic Press.
15. Hsu, W. H., and Crump, M. H. 1989. The adrenal gland. In Veterinary endocrinology and reproduction, eds. L. E. McDonald and M. H. Pineda, 4th ed., pp. 202-230. Philadelphia: Lea and Febiger.
16. Hughes, B. J., Forsell, J. H., Sleight, S. D., Kuo, C., and Shull, L. R. 1985. Assessment of pen-tachlorophenol toxicity in newborn calves: Clinicopathology and tissue residues. J. Anim. Sci. 61:1587-1603.
17. Jekat, F. W., Meisel, M. L., Eckard, R., and Winterhoff, H. 1994. Effects of pentachlorophenol (PCP) on the pituitary and thyroidal hormone regulation i n the rat. Toxicol. Lett. 71:9-25.
18. Joseph, I. B. J. K., Currie, W. D., and Rawlings, N. C. 1992. Luteinising hormone and follicle stimulating hormone secretion in ovariectomised ewes: Effects of time post-ovariectomy season and oestradiol. J. Reprod. Fertil. 94:511-523.
19. Joseph, I. B. J. K., Currie, W. D., Ravindra, J. P., Cook, S. J., and Rawlings, N. C. 1994. Oestradiol and the surge release of gonadotrophins in the ewe. Anim. Reprod. Sci. 34:217-230.
20. Kingsbury, D. L., and Rawlings, N. C. 1993. Effect of exposure to a boar on circulating concentrations of LH, FSH, cortisol and oestradiol in prepubertal gilts. J. Reprod. Fertil. 98:245-250.
21. Lahiri, P., and Sircar, S. 1991. Suppression of adrenocortical function in female mice by lindane (gamma-HCH). Toxicology. 66:75-79.
22. Lahiri, P., Chakravarty, S., Mondal, A., and Sircar, S. 1985. Effect of lindane on cytology and cytochemistry of exfoliated vaginal cells. Exp. Clin. Endocrinol. 85:303-308.
23. Laws, S. C., Carey, S. A., Hart, D. W., and Cooper, R. L. 1994. Lindane does not alter the estrogen receptor or the estrogen-dependent induction of progesterone receptors in sexually immature or ovariectomized adult rats. Toxicology. 92:127-142.
24. McEntee, K. 1990. Reproductive pathology of domestic animals. San Diego, CA: Academic Press.
25. Mears, G. J., Vesely, J. A., and Cheng, K. J. 1988. Plasma insulin and growth hormone in growing lambs fed monensin. Can. J. Anim. Sci. 68:165-171.
26. Merriam, G. R., and Wachter, K. W. 1982. Algorithms for the study of episodic hormone secretion. Am. J. Physiol. 243: E310-E318.
27. Mohammad, F. K., and St Omer, V. E. 1986. Behavioral and developmental effects in rats following in utero exposure to 2,4-D/2,4,5-T mixture. Neurobehav. Toxicol. Teratol. 8:551-560.
28. Nicolau, G. Y. 1983. Circadian rhythms of RNA, DNA and protein in the rat thyroid, adrenal and testis, in chronic pesticide exposure. IV. Effects of the herbicide 2,4-dichlorophenoxyacetic acid. Endocrinologie. 21:169-174.
29. Quast, J. F., Liberacki, A. B., and Breslin, W. J. 1993. Chlorpyrifos insecticide: Two-generation dietary reproduction study in Sprague-Dawley rats. Toxicologist. 13:372.
30. Roche, J. F. 1996. Control and regulation of folliculogenesis—A symposium in perspective. Rev. Reprod. 1:19-27.
31. Schulte, H. R., and Parzefall, W. 1980. Adaptive responses of rat liver to the gestagen and antiandrogen cyproterone acetate and other inducers. I. Induction of drug-metabolizing enzymes. Chem. Biol. Interact. 31:279-286.
32. Shaker, N., Hassan, G.A., el Nouty, F. D., Abo Elezz, Z., and Abd Allah, G. A. 1988. In vivo chronic effect of dimethoate and deltamethrin on rabbits. J. Environ. Sci. Health B 23:387-399.
33. Sircar, S., and Lahiri, P. 1989. Lindane (gamma-HCH) causes reproductive failure and fetotoxicity in mice. Toxicology. 59:171-177.
34. Sircar, S., and Lahiri, P. 1990. Effect of lindane on mitochondrial side-chain cleavage of cholesterol in mice. Toxicology. 61:41-46.
35. Sokal, K. J., and Rohlf, F. J. 1969. Biometry. San Francisco: W. H. Freeman.
36. Spencer, E. Y. 1982. Guide to the chemicals used in crop production, ed. Agriculture Canada Research Branch, 7th ed. London, ON: Research Centre.
37. Street, J. C., and Chadwick, R. W. 1975. Ascorbic acid requirements and metabolism in relation to organochlorine pesticides. Am. NY Acad. Sci. 258:132-143.
38. Tezak, Z., Simic, B., and Kniewald, J. 1992. Effect of pesticides on oestradiol-receptor complex formation in rat uterus cytosol. Food. Chem. Toxicol. 30:879-885.
39. Van den Berg, K. J. 1990. Interaction of chlorinated phenols with thyroxine binding sites of human transthyretin, albumin and thyroid binding globulin. Chem. Biol. Interact. 76:63-75.
40. Van den Berg, K. J., van Raaij, J. A., Bragt, P. C., and Notten, W. R. 1991. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Arch. Toxicol. 65:15-19.