Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicals

Environmental Toxicology and Chemistry

Volumn 15, Issue 2, 1996, Pages 194-202

  Jobling, Susan ^a   Sheahan, David ^b   Osborne, Julia A ^b   Matthiessen, Peter ^b   Sumpter, John P ^a  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b CENTRE FOR ENVIRONMENT   (United Kingdom)

Author keywords

Alkylphenol; Estrogen; Oncorhynchus mykiss; Rainbow trout; Testicular growth

Indexed keywords

4 NONYLPHENOL; 4 NONYLPHENOXYACETIC ACID; 4 TERT OCTYLPHENOL; AGRICULTURAL CHEMICAL; ALKYLPHENOL; ESTROGEN; ETHINYLESTRADIOL; INDUSTRIAL CHEMICAL; NONIONIC SURFACTANT; NONOXINOL 2; UNCLASSIFIED DRUG; VITELLOGENIN; WATER;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; ESTROGEN ACTIVITY; GROWTH INHIBITION; MALE; NONHUMAN; PLASMA; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAINBOW TROUT; REPRODUCTION; SPECTROFLUOROMETRY; TESTIS;

ANIMALIA; CELLULAR ORGANISMS; MYKISS; ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 0030022687     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(1996)015<0194:IOTGIR>2.3.CO;2     Document Type: Article

References (63)

1. Stone, R. 1994. Environmental estrogens stir debate. Science 265:308-310.
2. Raloff, J. 1994. That feminine touch: Are men suffering from prenatal or childhood exposures to "hormonal" toxicants? Science News 145:49-64.
3. Raloff, J. 1994. The gender benders: Are environmental "hormones" emasculating wildlife? Science News 145:24-27.
4. Colborn, T. and C. Clement, eds. 1992. Chemically-induced alterations in sexual and functional development: The wildlife/human connection. In M.A. Mehlman, ed., Advances in Modern Environmental Toxicology, Vol. 21. Princeton Scientific Publishing Company, Princeton, NJ, USA.
5. McLachlan, J.A, ed. 1980. Estrogens in the Environment. Elsevier, New York, NY, USA.
6. McLachlan, J.A, ed. 1985. Estrogens in the Environment II. Elsevier, New York, NY, USA.
7. Soto, A.M., H. Justicia, J.W. Wray and C. Sonnenschein. 1991. p-Nonylphenol: An estrogenic xenobiotic released from "modified" polystyrene. Environ. Health Perspect. 92:167-172.
8. Jobling, S. and J.P. Sumpter. 1993. Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Onchorhynchus mykiss) hepatocytes. Aquat. Toxicol. 27:361-372.
9. Krishnan, A.V., P. Stathis, S.F. Permuth and L. Tokes. 1993. Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 132:2279-2286.
10. Ahel, M., J. Conrad and W. Giger. 1987. Persistent organic chemicals in sewage effluents: 3. Determination of nonylphenoxy carboxylic acids by high resolution gas chromatography. Environ. Sci. Technol. 21:697.
11. Thoumelin, G. 1991. Presence et comportement dans le milieu aquatique des alkylbenzenesulfonates lineaires (LAS) et des alkylphenols ethoxyles (APE); mise au point. Environ. Technol. 12:1037-1045.
12. Naylor, C.G. 1992. Environmental fate of alkylphenol ethoxylates. Soap/Cosmetics/Chemical Specialities 72:27-31.
13. Clark, L.B., R.T. Rosen, T.G. Hartman, J.B. Louis, I.H. Suffet, R.L. Lipincott and J.D. Rosen. 1992. Determination of alkylphenol ethoxylates and their acetic acid derivatives in drinking water by particle beam liquid chromatography/mass spectrometry. Int. J. Environ. Anal. Chem. 47:167-180.
14. Argese, E., A. Marcomini, P. Miana, C. Bettiol and G. Perin. 1994. Submitochondrial particle response to linear alkylbenzene sulfonates, nonylphenol polyethoxylates and their biodegradation derivatives. Environ. Toxicol. Chem. 13:737-742.
15. Giger, W., P.H. Brunner and C. Schaffner. 1984. 4-Nonylphenol in sewage sludge: Accumulation of toxic metabolites from nonionic surfactants. Science 225:623-625.
16. Chemical Manufacturers Association. 1994. Alkylphenol ethoxylates in the environment. Alkylphenol and Ethoxylates Panel, Washington, DC, USA.
17. Giger, W., M. Ahel, M. Koch, H.U. Laubscher, C. Schaffner and J. Schneider. 1987. Behaviour of alkylphenol polyethoxylate surfactants and of nitrilotriacetate in sewage treatment. Water. Sci. Technol. 19:449-460.
18. Ekelund, R., A. Bergman, A. Granmo and M. Berggren. 1990. Bioaccumulation of 4-nonylphenol in marine animals - A re-evaluation. Environ. Pollut. 64:107-120.
19. Ahel, M., J. McEvoy and W. Giger. 1993. Bioaccumulation of the lipophilic metabolites of nonionic surfactants in freshwater organisms. Environ. Pollut. 79:243-248.
20. White, R., S. Jobling, S.A. Hoare, J.P. Sumpter and M.G. Parker. 1994. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 135:175-182.
21. Billard, R. 1992. Reproduction in rainbow trout: Sex differentiation, dynamics of gametogenesis, biology and preservation of gametes. Aquaculture 100:262-298.
22. Trudeau, V.L., R.E. Peter and B.D. Soley. 1991. Testosterone and estradiol potentiate the serum gonadatropin response to gonadotropin releasing hormone in goldfish. Biol. Reprod. 48:951-960.
23. Chen, T.T. 1983. Identification and characterisation of estrogen-responsive gene products in the liver of rainbow trout. Can. J. Biochem. Cell Biol. 61:802-810.
24. Scott, A.P. and J.P. Sumpter. 1983. A comparison of the female reproductive cycles of autumn and winter-spawning strains of rainbow trout (Salmo gairdneri). Gen. Comp. Endocrinol. 52:79-85.
25. McLachlan, J.A. and R.L. Dixon. 1976. Transplacental toxicity of diethylstilbestrol: A special problem in safety evaluation. In M.A. Mehlman, R.E. Shapiro and H. Blumenthal, eds., Advances in Modern Toxicology. Hemisphere, Washington, DC, USA, pp. 423-448.
26. Newbold, R.R. and J.A. McLachlan. 1985. Diethylstilbestrol associated effects in murine genital tract development. In J.A. McLachlan, ed., Estrogens in the Environment. Elsevier Science, New York, NY, USA, pp. 288-315.
27. Fry, D.M. and C.K. Toone. 1981. DDT-Induced feminization of gull embryos. Science 213:922-924.
28. Guillette, L.J., T.S. Gross, G.R. Mason, J.M. Matter, H.F. Percival and A.R. Woodward. 1994. Developmental abnormalities of the gonad and abnormal sex-hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ. Health Perspect. 102:680-688.
29. Herman, R.L. and H.L. Kincaid. 1988. Pathological effects of orally administered estradiol to rainbow trout. Aquaculture 72:165-172.
30. Wester, P.W. and J.H. Canton. 1986. Histopathological study of Oryzias latipes (medaka) after long term β-hexachlorocyclohexane exposure. Aquat. Toxicol. 9:21-45.
31. Wester, P.W., J.H. Canton and A. Bisschop. 1985. Histopathological study of Poecilia reticulata (guppy) after long-term β-hexachlorocyclohexane exposure. Aquat. Toxicol. 6:271-296.
32. Sheahan, D.A., D. Bucke, P. Matthiessen, J.P. Sumpter, M.F. Kirby, P. Neall and M. Waldock. 1994. The effects of low levels of 17α-ethynylestradiol upon plasma vitellogenin levels in male and female rainbow trout, Oncorhynchus mykiss (Walbaum) held at two acclimation temperatures. In R. Muller and R. Lloyd, eds., Sublethal and Chronic Effects of Pollutants on Freshwater Fish. Fishing News Books, Oxford, UK, pp. 99-112.
33. Sumpter, J.P. 1985. The purification, radioimmunoassay and plasma levels of vitellogenin from the rainbow trout Salmo gairdneri. In B. Lofts and W.H. Holmes, eds., Trends in Comparative Endocrinology. Hong Kong University Press, Hong Kong, China, pp. 355-357.
34. Scott, A.P. and J.P. Sumpter. 1989. Seasonal variations in testicular germ cell stages and in plasma concentrations of sex steroids in male rainbow trout (Salmo gairdneri) maturing at 2 years old. Gen. Comp. Endocrinol. 73:46-58.
35. Flouriot, G., C. Vaillant, G. Salbert, C. Pelissero, J.M. Guiraud and Y. Valotaire. 1993. Monolayer and aggregate cultures of rainbow trout hepatocytes: Long term and stable liver-specific expression in aggregates. J. Cell Sci. 105:407.
36. Billard, R., B. Breton and M. Richard. 1981. On the inhibitory effect of some steroids on spermatogenesis in adult rainbow trout (Salmo gairdneri). Can. J. Zool. 59:1479-1487.
37. Klungland, H., O. Andersen, G. Kisen, P. Alestrom and L. Tora. 1993. Estrogen-receptor binds to the salmon GnRH gene in a region with long palindromic sequences. Mol. Cell. Endocr. 95:147-154.
38. Xiong, F., D. Liu, H. Elsholtz and C.L. Hew. 1994. The chinook salmon gonadotropin IIb subunit gene contains a strong minimal promoter with a proximal negative element. Mol. Endocrinol. 8:771-781.
39. Xiong, F., D. Liu, Y.L. Drean, H.P. Elsholtz and C.L. Hew. 1994. Differential recruitment of steroid hormone response elements may dictate the expression of the pituitary gonadotropin IIb subunit gene during salmon maturation. Mol. Endocrinol. 8:782-793.
40. Hunter, G.A. and E.M. Donaldson. 1983. Hormonal sex control and its application to fish culture. In W.S. Hoar, D.J. Randall and E.M. Donaldson, eds., Fish Physiology. Academic, New York, NY, USA, pp. 223-303.
41. Piferrer, F. and E.M. Donaldson. 1989. Gonadal ontogenesis in coho salmon, Oncorhynchus kisutch, after a single treatment with androgen or estrogen during ontogenesis. Aquaculture 77:251-262.
42. Bye, V.J. and R.F. Lincoln. 1986. Commercial methods for the control of sexual maturation in rainbow trout (Salmo gairdneri R.). Aquaculture 57:299-309.
43. Haux, C. and B. Norberg. 1985. Effect of sexual maturation and estradiol-17β on liver content of protein, lipids, glycogen and nucleic acids in juvenile rainbow trout, Salmo gairdneri. Comp. Biochem. Physiol. B 81:275-279.
44. Washburn, B.S., J.S. Krantz, E.H. Avery and R.A. Freedland. 1993. Effects of estrogen on gluconeogenesis and related parameters in male rainbow trout. Am. J. Physiol. 264:R720-R725.
45. Tyler, C.R., J.P. Sumpter and N.R. Bromage. 1988. In vivo ovarian uptake and processing of vitellogenin in the rainbow trout Salmo gairdneri. J. Exp. Zool. 246:171-179.
46. Tyler, C.R., J.P. Sumpter and N.R. Bromage. 1988. The selectivity of protein sequestration by vitellogenic oocytes of the rainbow trout Salmo gairdneri in vivo. J. Exp. Zool. 248:199-206.
47. Hyllner, S.J., D.O. Oppen-Bernsten, J.V. Helvik, B.T. Walther and C. Haux. 1991. Oestradiol-17β induces the major vitelline envelope proteins in both sexes in teleosts. J. Endocrinol. 131:229-236.
48. Specker, J.L. and C.V. Sullivan. 1993. Vitellogenesis in fishes: Status and perspectives. In K.G. Davey, R.E. Peter and S.S. Tobe, eds., Perspectives in Comparative Endocrinology. National Research Council of Canada, Ottawa, ON, Canada, pp. 304-315.
49. Campbell, P.M., T.G. Pottinger and J.P. Sumpter. 1994. Changes in the affinity of estrogen and androgen receptors accompanying changes in receptor abundance in brown and rainbow trout. Gen. Comp. Endocrinol. 94:329-340.
50. Ahel, M. and W. Giger. 1985. Determination of alkylphenols and alkylphenol mono- and diethoxylates in environmental samples by high-performance liquid chromatography. Anal. Chem. 57:1577-1583.
51. Naylor, G.C., J.P. Mierure, J.A. Weeks, F.J. Castaldi and R.R. Romano. 1992. Alkylphenol ethoxylates in the environment. J. Am. Oil Chem. Soc. 69:695-703.
52. Ahel, M., W. Giger and M. Koch. 1994. Behaviour of alkylphenol polyethoxylate surfactants in the aquatic environment. 1. Occurrence and transformation in sewage treatment. Water. Res. 28:1131-1142.
53. Di Corcia, A., R. Samperi and A. Marcomini. 1994. Monitoring aromatic surfactants and their biodegradation intermediates in raw and treated sewages by solid-phase extraction and liquid chromatography. Environ. Sci. & Technol. 28:850-858.
54. Ahel, M. and W. Giger. 1985. Determination of nonionic surfactants of the alkylphenol polyethoxylate type by high-performance liquid chromatography. Anal. Chem. 57:2584-2590.
55. Warhurst, A.M. 1995. An environmental assessment of alkylphenol ethoxylates and alkylphenols. Friends of the Earth, London, UK.
56. Ahel, M., W. Giger and C. Schaffner. 1994. Behaviour of alkylphenol polyethoxylate surfactants in the aquatic environment. 2. Occurrence and transformation in rivers. Water. Res. 28:1143-1152.
57. Ahel, M., D. Hrsak and W. Giger. 1994. Aerobic transformation of short-chain alkylphenol polyethoxylates by mixed bacterial cultures. Arch. Environ. Contain. Toxicol. 26:540-548.
58. Ball, H.A., M. Reinhard and P.L. McCarty. 1989 Biotransformation of halogenated and nonhalogenated octylphenol polyethoxylate residues under aerobic and anaerobic conditions. Environ. Sci. Technol. 23:951-961.
59. Marcomini, A., B. Pavoni, A. Sfriso and A.A. Orio. 1990. Persistent metabolites of alkylphenol polyethoxylates in the marine environment. Mar. Chem. 29:307-323.
60. Ahel, M. and W. Giger. 1993. Partitioning of alkylphenols and alkylphenol polyethoxylates between water and organic solvents. Chemosphere 26:1471-1478.
61. Soto, A.M., K.L. Chung and C. Sonnenschein. 1994. The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environ. Health Perspect. 102:380-383.
62. Sumpter, J.P. and S. Jobling. 1996. Vitellogenesis as a biomarker for oestrogenic contamination of the aquatic environment. Environ. Health Perspect. (in press).
63. Purdom, C.E., P.A. Hardiman, V.J. Bye, N.C. Eno, C.R. Tyler and J.P. Sumpter. 1994. Estrogenic effects of effluents from sewage treatment works. Chem. Ecol. 8:275-285.