Purified brominated indole derivatives from dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines

Marine Drugs

Volumn 11, Issue 10, 2013, Pages 3802-3822

  Esmaeelian, Babak ^a   Benkendorff, Kirsten ^b   Johnston, Martin R ^a   Abbott, Catherine A ^a,c  

^a FLINDERS UNIVERSITY   (Australia)

^b SOUTHERN CROSS UNIVERSITY   (Australia)

^c FLINDERS UNIVERSITY   (Australia)

Author keywords

Apoptosis; Brominated indoles; Colorectal cancer; Marine mollusc

Indexed keywords

6 BROMOISATIN; ANTINEOPLASTIC AGENT; BROMINATED INDOLE DERIVATIVE; CASPASE 3; CASPASE 7; INDOLE DERIVATIVE; NATURAL PRODUCT; TYRINDOLENINONE; TYRINDOLINONE; TYRINDOXYLSULPHATE; TYRIVERDIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL VIABILITY; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DICATHAIS ORBITA; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; DRUG STRUCTURE; EGG; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LIQUID CHROMATOGRAPHY; MARINE SNAIL; PROTON NUCLEAR MAGNETIC RESONANCE;

DICATHAIS ORBITA; GASTROPODA; MOLLUSCA;

ANIMALS; APOPTOSIS; BIOLOGICAL FACTORS; CACO-2 CELLS; CASPASE 3; CASPASE 7; CELL CYCLE CHECKPOINTS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; COLORECTAL NEOPLASMS; G2 PHASE; GASTROPODA; HT29 CELLS; HUMANS; HYDROCARBONS, BROMINATED; INDOLES; ISATIN; NECROSIS;

EID: 84887028286     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11103802     Document Type: Article

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