Brain hemorrhages in cerebral amyloid angiopathy

Seminars in Thrombosis and Hemostasis

Volumn 39, Issue 8, 2013, Pages 955-962

  Yamada, Masahito ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

amyloid protein; cerebral amyloid angiopathy; cerebrovascular disorders; intracerebral hemorrhage; risk factors

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E; BIOLOGICAL MARKER; CYSTATIN C; GELSOLIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEMBRANE METALLOENDOPEPTIDASE; OLIGOMER; PITTSBURGH COMPOUND B; PREALBUMIN; PRESENILIN 1; PRION PROTEIN; SCLEROPROTEIN;

ACUTE HEART INFARCTION; ANTICOAGULATION; ARTICLE; BASAL GANGLION; BLOOD CLOT LYSIS; BLOOD PRESSURE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; BRAIN STEM; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITION; COMPUTER ASSISTED TOMOGRAPHY; CONSCIOUSNESS; DEMENTIA; DIAGNOSTIC ACCURACY; DISEASE COURSE; DNA POLYMORPHISM; FATALITY; FIBRINOLYTIC THERAPY; GENOTYPE; GRAY MATTER; HEAD INJURY; HEADACHE; HEREDITY; HUMAN; HYALINE DEGENERATION; HYPERTENSION; IMMUNOTHERAPY; INFLAMMATION; LIGAND BINDING; LUNG EMBOLISM; MENINGOENCEPHALITIS; MIGRAINE AURA; MILD COGNITIVE IMPAIRMENT; MOLECULAR PATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PARESIS; PATHOPHYSIOLOGY; PERFUSION; POSITRON EMISSION TOMOGRAPHY; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK FACTOR; SEIZURE; SIDEROSIS; SUBARACHNOID HEMORRHAGE; SUSCEPTIBILITY WEIGHTED IMAGING; THALAMUS; TRANSIENT ISCHEMIC ATTACK; VASCULAR AMYLOIDOSIS; WHITE MATTER LESION;

AMYLOID BETA-PEPTIDES; APOLIPOPROTEINS E; CEREBRAL AMYLOID ANGIOPATHY; HUMANS; INTRACRANIAL HEMORRHAGES; MAGNETIC RESONANCE IMAGING; MUTATION; POSITRON-EMISSION TOMOGRAPHY; RISK FACTORS;

EID: 84887025763     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0033-1357489     Document Type: Article

References (87)

1. Yamada M., Naiki H. Cerebral amyloid angiopathy. Prog Mol Biol Transl Sci: 2012; 107 7 41 78
2. Yamada M. Predicting cerebral amyloid angiopathy-related intracerebral hemorrhages and other cerebrovascular disorders in Alzheimer's disease. Front Neurol: 2012; 3 64
3. Prelli F., Castaño E., Glenner G. G., Frangione B. Differences between vascular and plaque core amyloid in Alzheimer's disease. J Neurochem: 1988; 51 2 648 651
4. Suzuki N., Iwatsubo T., Odaka A., Ishibashi Y., Kitada C., Ihara Y. High tissue content of soluble β 1-40 is linked to cerebral amyloid angiopathy. Am J Pathol: 1994; 145 2 452 460 (Pubitemid 24245845)
5. Samarasekera N., Smith C., Al-Shahi Salman R. The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry: 2012; 83 3 275 281
6. Yamada M., Tsukagoshi H., Otomo E., Hayakawa M. Cerebral amyloid angiopathy in the aged. J Neurol: 1987; 234 6 371 376
7. Hirohata M., Yoshita M., Ishida C., et al. Clinical features of non-hypertensive lobar intracerebral hemorrhage related to cerebral amyloid angiopathy. Eur J Neurol: 2010; 17 6 823 829
8. Meretoja A., Strbian D., Putaala J., et al. SMASH-U: a proposal for etiologic classification of intracerebral hemorrhage. Stroke: 2012; 43 10 2592 2597
9. Béjot Y., Cordonnier C., Durier J., Aboa-Eboulé C., Rouaud O., Giroud M. Intracerebral haemorrhage profiles are changing: results from the Dijon population-based study. Brain: 2013; 136 Pt 2 658 664
10. Itoh Y., Yamada M., Hayakawa M., Otomo E., Miyatake T. Cerebral amyloid angiopathy: a significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly. J Neurol Sci: 1993; 116 2 135 141 (Pubitemid 23176848)
11. Yamada M., Itoh Y., Otomo E., Hayakawa M., Miyatake T. Subarachnoid haemorrhage in the elderly: a necropsy study of the association with cerebral amyloid angiopathy. J Neurol Neurosurg Psychiatry: 1993; 56 5 543 547 (Pubitemid 23171788)
12. Ohshima T., Endo T., Nukui H., Ikeda S., Allsop D., Onaya T. Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage. Stroke: 1990; 21 3 480 483 (Pubitemid 20089800)
13. Hanyu H., Tanaka Y., Shimizu S., Takasaki M., Abe K. Cerebral microbleeds in Alzheimer's disease. J Neurol: 2003; 250 12 1496 1497
14. Nakata-Kudo Y., Mizuno T., Yamada K., et al. Microbleeds in Alzheimer disease are more related to cerebral amyloid angiopathy than cerebrovascular disease. Dement Geriatr Cogn Disord: 2006; 22 1 8 14
15. Cordonnier C., van der Flier W. M., Sluimer J. D., Leys D., Barkhof F., Scheltens P. Prevalence and severity of microbleeds in a memory clinic setting. Neurology: 2006; 66 9 1356 1360 (Pubitemid 43739644)
16. Cordonnier C., Al-Shahi Salman R., Wardlaw J. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain: 2007; 130 Pt 8 1988 2003 (Pubitemid 47236609)
17. Pettersen J. A., Sathiyamoorthy G., Gao F. Q., et al. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol: 2008; 65 6 790 795 (Pubitemid 351831457)
18. Brundel M., Heringa S. M., de Bresser J., et al. High prevalence of cerebral microbleeds at 7Tesla MRI in patients with early Alzheimer's disease. J Alzheimers Dis: 2012; 31 2 259 263
19. Yates P. A., Sirisriro R., Villemagne V. L., Farquharson S., Masters C. L., Rowe C. C.; AIBL Research Group. Cerebral microhemorrhage and brain β-amyloid in aging and Alzheimer disease. Neurology: 2011; 77 1 48 54
20. Dierksen G. A., Skehan M. E., Khan M. A., et al. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Ann Neurol: 2010; 68 4 545 548
21. Feldman H. H., Maia L. F., Mackenzie I. R., Forster B. B., Martzke J., Woolfenden A. Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease. Stroke: 2008; 39 10 2894 2897
22. Kumar S., Goddeau R. P. Jr, Selim M. H., et al. Atraumatic convexal subarachnoid hemorrhage: clinical presentation, imaging patterns, and etiologies. Neurology: 2010; 74 11 893 899
23. Linn J., Halpin A., Demaerel P., et al. Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy. Neurology: 2010; 74 17 1346 1350
24. Vernooij M. W., Ikram M. A., Hofman A., Krestin G. P., Breteler M. M., van der Lugt A. Superficial siderosis in the general population. Neurology: 2009; 73 3 202 205
25. Izenberg A., Aviv R. I., Demaerschalk B. M., et al. Crescendo transient Aura attacks: a transient ischemic attack mimic caused by focal subarachnoid hemorrhage. Stroke: 2009; 40 12 3725 3729
26. Beitzke M., Gattringer T., Enzinger C., Wagner G., Niederkorn K., Fazekas F. Clinical presentation, etiology, and long-term prognosis in patients with nontraumatic convexal subarachnoid hemorrhage. Stroke: 2011; 42 11 3055 3060
27. Charidimou A., Peeters A., Fox Z., et al. Spectrum of transient focal neurological episodes in cerebral amyloid angiopathy: multicentre magnetic resonance imaging cohort study and meta-analysis. Stroke: 2012; 43 9 2324 2330
28. Linn J., Wollenweber F. A., Lummel N., et al. Superficial siderosis is a warning sign for future intracranial hemorrhage. J Neurol: 2013; 260 1 176 181
29. Zhu Y. C., Chabriat H., Godin O., et al. Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging. J Neurol: 2012; 259 3 530 536
30. Kimberly W. T., Gilson A., Rost N. S., et al. Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology: 2009; 72 14 1230 1235
31. Gregoire S. M., Charidimou A., Gadapa N., et al. Acute ischaemic brain lesions in intracerebral haemorrhage: multicentre cross-sectional magnetic resonance imaging study. Brain: 2011; 134 Pt 8 2376 2386
32. Yamada M., Itoh Y., Suematsu N., Otomo E., Matsushita M. Vascular variant of Alzheimer's disease characterized by severe plaque-like beta protein angiopathy. Dement Geriatr Cogn Disord: 1997; 8 3 163 168 (Pubitemid 27183221)
33. Cordonnier C., Leys D., Dumont F., et al. What are the causes of pre-existing dementia in patients with intracerebral haemorrhages? Brain: 2010; 133 11 3281 3289
34. Arvanitakis Z., Leurgans S. E., Wang Z., Wilson R. S., Bennett D. A., Schneider J. A. Cerebral amyloid angiopathy pathology and cognitive domains in older persons. Ann Neurol: 2011; 69 2 320 327
35. Oh U., Gupta R., Krakauer J. W., Khandji A. G., Chin S. S., Elkind M. S. Reversible leukoencephalopathy associated with cerebral amyloid angiopathy. Neurology: 2004; 62 3 494 497 (Pubitemid 38200871)
36. Eng J. A., Frosch M. P., Choi K., Rebeck G. W., Greenberg S. M. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol: 2004; 55 2 250 256 (Pubitemid 38167002)
37. Scolding N. J., Joseph F., Kirby P. A., et al. Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy. Brain: 2005; 128 Pt 3 500 515 (Pubitemid 40380186)
38. Kinnecom C., Lev M. H., Wendell L., et al. Course of cerebral amyloid angiopathy-related inflammation. Neurology: 2007; 68 17 1411 1416 (Pubitemid 46661556)
39. Nandigam R. N., Viswanathan A., Delgado P., et al. MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol: 2009; 30 2 338 343
40. Ii Y., Maeda M., Kida H., et al. In vivo detection of cortical microinfarcts on ultrahigh-field MRI. J Neuroimaging: 2013; 23 1 28 32
41. Johnson K. A., Gregas M., Becker J. A., et al. Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol: 2007; 62 3 229 234 (Pubitemid 47525398)
42. Bacskai B. J., Frosch M. P., Freeman S. H., et al. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol: 2007; 64 3 431 434 (Pubitemid 46425701)
43. Ly J. V., Donnan G. A., Villemagne V. L., et al. 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage. Neurology: 2010; 74 6 487 493
44. Gurol M. E., Dierksen G., Betensky R., et al. Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy. Neurology: 2012; 79 4 320 326
45. Verbeek M. M., Kremer B. P., Rikkert M. O., Van Domburg P. H., Skehan M. E., Greenberg S. M. Cerebrospinal fluid amyloid β(40) is decreased in cerebral amyloid angiopathy. Ann Neurol: 2009; 66 2 245 249
46. Hernandez-Guillamon M., Delgado P., Penalba A., et al. Plasma β-amyloid levels in cerebral amyloid angiopathy-associated hemorrhagic stroke. Neurodegener Dis: 2012; 10 1-4 320 323
47. Knudsen K. A., Rosand J., Karluk D., Greenberg S. M. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology: 2001; 56 4 537 539 (Pubitemid 32172884)
48. Greene G. M., Godersky J. C., Biller J., Hart M. N., Adams H. P. Jr. Surgical experience with cerebral amyloid angiopathy. Stroke: 1990; 21 11 1545 1549
49. Greenberg S. M., Rebeck G. W., Vonsattel J. P., Gomez-Isla T., Hyman B. T. Apolipoprotein E ε 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol: 1995; 38 2 254 259
50. Premkumar D. R., Cohen D. L., Hedera P., Friedland R. P., Kalaria R. N. Apolipoprotein E-ε4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol: 1996; 148 6 2083 2095
51. Nicoll J. A., Burnett C., Love S., et al. High frequency of apolipoprotein E ε 2 allele in hemorrhage due to cerebral amyloid angiopathy. Ann Neurol: 1997; 41 6 716 721 (Pubitemid 27249176)
52. Brouwers H. B., Biffi A., McNamara K. A., et al. Apolipoprotein E genotype is associated with CT angiography spot sign in lobar intracerebral hemorrhage. Stroke: 2012; 43 8 2120 2125
53. O'Donnell H. C., Rosand J., Knudsen K. A., et al. Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage. N Engl J Med: 2000; 342 4 240 245 (Pubitemid 30058955)
54. Thal D. R., Ghebremedhin E., Rüb U., Yamaguchi H., Del Tredici K., Braak H. Two types of sporadic cerebral amyloid angiopathy. J Neuropathol Exp Neurol: 2002; 61 3 282 293 (Pubitemid 34212603)
55. Maxwell S. S., Jackson C. A., Paternoster L., et al. Genetic associations with brain microbleeds: Systematic review and meta-analyses. Neurology: 2011; 77 2 158 167
56. Leclercq P. D., Murray L. S., Smith C., Graham D. I., Nicoll J. A., Gentleman S. M. Cerebral amyloid angiopathy in traumatic brain injury: association with apolipoprotein E genotype. J Neurol Neurosurg Psychiatry: 2005; 76 2 229 233 (Pubitemid 40143713)
57. Hamaguchi T., Okino S., Sodeyama N., et al. Association of a polymorphism of the transforming growth factor-β1 gene with cerebral amyloid angiopathy. J Neurol Neurosurg Psychiatry: 2005; 76 5 696 699 (Pubitemid 40569681)
58. Peila R., Yucesoy B., White L. R., et al. A TGF-β1 polymorphism association with dementia and neuropathologies: the HAAS. Neurobiol Aging: 2007; 28 9 1367 1373 (Pubitemid 47081228)
59. Yamada M. Risk factors for cerebral amyloid angiopathy in the elderly. Ann N Y Acad Sci: 2002; 977 37 44 (Pubitemid 35418135)
60. Yamada M. Cerebral amyloid angiopathy and gene polymorphisms. J Neurol Sci: 2004; 226 1-2 41 44 (Pubitemid 39505403)
61. Yamada M., Sodeyama N., Itoh Y., et al. Association of presenilin-1 polymorphism with cerebral amyloid angiopathy in the elderly. Stroke: 1997; 28 11 2219 2221 (Pubitemid 27497926)
62. Yamada M., Sodeyama N., Itoh Y., et al. Association of α1-antichymotrypsin polymorphism with cerebral amyloid angiopathy. Ann Neurol: 1998; 44 1 129 131 (Pubitemid 28323663)
63. Yamada M., Sodeyama N., Itoh Y., et al. Association of neprilysin polymorphism with cerebral amyloid angiopathy. J Neurol Neurosurg Psychiatry: 2003; 74 6 749 751 (Pubitemid 36628287)
64. Christoforidis M., Schober R., Krohn K. Genetic-morphologic association study: association between the low density lipoprotein-receptor related protein (LRP) and cerebral amyloid angiopathy. Neuropathol Appl Neurobiol: 2005; 31 1 11 19 (Pubitemid 40222821)
65. Domingues-Montanari S., Hernandez-Guillamon M., Fernandez-Cadenas I., et al. Stroke Project Cerebrovascular Diseases Study Group, Spanish Society of Neurology. ACE variants and risk of intracerebral hemorrhage recurrence in amyloid angiopathy. Neurobiol Aging: 2011; 32 3 e13 e22
66. Thal D. R., Papassotiropoulos A., Saido T. C., et al. Capillary cerebral amyloid angiopathy identifies a distinct APOE ε4-associated subtype of sporadic Alzheimer's disease. Acta Neuropathol: 2010; 120 2 169 183
67. Biffi A., Shulman J. M., Jagiella J. M., et al. Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology: 2012; 78 5 334 341
68. Arima H., Tzourio C., Anderson C., et al. PROGRESS Collaborative Group Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trial. Stroke: 2010; 41 2 394 396
69. Rosand J., Hylek E. M., O'Donnell H. C., Greenberg S. M. Warfarin-associated hemorrhage and cerebral amyloid angiopathy: a genetic and pathologic study. Neurology: 2000; 55 7 947 951
70. McCarron M. O., Nicoll J. A. Cerebral amyloid angiopathy and thrombolysis-related intracerebral haemorrhage. Lancet Neurol: 2004; 3 8 484 492 (Pubitemid 38903099)
71. Charidimou A., Kakar P., Fox Z., Werring D. J. Cerebral microbleeds and the risk of intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry: 2013; 84 3 277 280
72. Charidimou A., Shakeshaft C., Werring D. J. Cerebral microbleeds on magnetic resonance imaging and anticoagulant-associated intracerebral hemorrhage risk. Front Neurol: 2012; 3 133
73. Vernooij M. W., Haag M. D., van der Lugt A., et al. Use of antithrombotic drugs and the presence of cerebral microbleeds: the Rotterdam Scan Study. Arch Neurol: 2009; 66 6 714 720
74. Thoonsen H., Richard E., Bentham P., et al. Aspirin in Alzheimer's disease: increased risk of intracerebral hemorrhage: cause for concern? Stroke: 2010; 41 11 2690 2692
75. Boche D., Zotova E., Weller R. O., et al. Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain. Brain: 2008; 131 Pt 12 3299 3310
76. Orgogozo J. M., Gilman S., Dartigues J. F., et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology: 2003; 61 1 46 54 (Pubitemid 36818745)
77. Nicoll J. A., Wilkinson D., Holmes C., Steart P., Markham H., Weller R. O. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med: 2003; 9 4 448 452 (Pubitemid 36460079)
78. Sperling R., Salloway S., Brooks D. J., et al. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurol: 2012; 11 3 241 249
79. Mandybur T. I. Cerebral amyloid angiopathy: the vascular pathology and complications. J Neuropathol Exp Neurol: 1986; 45 1 79 90 (Pubitemid 16189845)
80. Vonsattel J. P., Myers R. H., Hedley-Whyte E. T., Ropper A. H., Bird E. D., Richardson E. P. Jr. Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol: 1991; 30 5 637 649
81. Maeda A., Yamada M., Itoh Y., Otomo E., Hayakawa M., Miyatake T. Computer-assisted three-dimensional image analysis of cerebral amyloid angiopathy. Stroke: 1993; 24 12 1857 1864 (Pubitemid 23352716)
82. Yamada M., Itoh Y., Shintaku M., et al. Immune reactions associated with cerebral amyloid angiopathy. Stroke: 1996; 27 7 1155 1162 (Pubitemid 26226947)
83. Revesz T., Holton J. L., Lashley T., et al. Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies. Acta Neuropathol: 2009; 118 1 115 130
84. Hernandez-Guillamon M., Martinez-Saez E., Delgado P., et al. MMP-2/MMP-9 plasma level and brain expression in cerebral amyloid angiopathy-associated hemorrhagic stroke. Brain Pathol: 2012; 22 2 133 141
85. Lee J. M., Yin K., Hsin I., et al. Matrix metalloproteinase-9 in cerebral-amyloid-angiopathy-related hemorrhage. J Neurol Sci: 2005; 229-230 249 254 (Pubitemid 40341590)
86. McCarron M. O., Nicoll J. A., Stewart J., et al. The apolipoprotein E ε2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage. J Neuropathol Exp Neurol: 1999; 58 7 711 718 (Pubitemid 29328500)
87. Biffi A., Anderson C. D., Jagiella J. M., et al. International Stroke Genetics Consortium. APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study. Lancet Neurol: 2011; 10 8 702 709