Novel therapeutic targets: The PERKs of inhibiting the integrated stress response

Cell Cycle

Volumn 5, Issue 24, 2006, Pages 2874-2877

  Blais, Jaime ^a   Bell, John C ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

Anti angiogenic; Cancer; Hypoxia; PERK; Stress response; Tumor perfusion

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; LEUCINE ZIPPER PROTEIN; MESSENGER RNA; PERK PROTEIN; PROTEIN KINASE; ANTINEOPLASTIC AGENT; PERK KINASE; PROTEIN KINASE R; UNCLASSIFIED DRUG;

CELL SURVIVAL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HYPOXIA; MICROENVIRONMENT; MICROVASCULATURE; NONHUMAN; PROTEIN SYNTHESIS; REOXYGENATION; REVIEW; STRESS; TUMOR GROWTH; ADAPTATION; ANIMAL; ARTICLE; CELL HYPOXIA; DRUG ANTAGONISM; DRUG EFFECT; MOUSE; PROTEIN FOLDING;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTINEOPLASTIC AGENTS; CELL HYPOXIA; EIF-2 KINASE; HUMANS; MICE; PROTEIN FOLDING;

EID: 33845680589     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.24.3597     Document Type: Review

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