Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice

Journal of Allergy and Clinical Immunology

Volumn 132, Issue 5, 2013, Pages

  Cui, Hong ^a   Okamoto, Yasuo ^a   Yoshioka, Kazuaki ^a   Du, Wa ^a   Takuwa, Noriko ^a,b   Zhang, Wei ^c   Asano, Masahide ^a   Shibamoto, Toshishige ^c   Takuwa, Yoh ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b ISHIKAWA PREFECTURAL NURSING UNIVERSITY   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

adherens junction; anaphylaxis; endothelial nitric oxide synthase; nitric oxide; nitrosylation; Sphingosine 1 phosphate; vascular permeability; VE cadherin; catenin

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BETA CATENIN; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2 AGONIST; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ANAPHYLACTIC SHOCK; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL JUNCTION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE DELETION; LUNG; MALE; MOUSE; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WILD TYPE;

EID: 84887022061     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.07.026     Document Type: Article

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