Neuroprotection and lifespan extension in Ppt1-/- mice by NtBuHA: Therapeutic implications for INCL

Nature Neuroscience

Volumn 16, Issue 11, 2013, Pages 1608-1617

  Sarkar, Chinmoy ^a   Chandra, Goutam ^a   Peng, Shiyong ^a   Zhang, Zhongjian ^a   Liu, Aiyi ^a   Mukherjee, Anil B ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYLAMINE; N (TERT BUTYL)HYDROXYLAMINE; PALMITOYL PROTEIN THIOESTERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME DEFICIENCY; GENE; GENE MUTATION; HUMAN; HUMAN CELL; LIFE EXTENSION; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; NEUROPROTECTION; NONHUMAN; PPT1 GENE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CARBON ISOTOPES; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HYDROXYLAMINES; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONAL CEROID-LIPOFUSCINOSES; NEURONS; NEUROPROTECTIVE AGENTS; PALMITOYL COENZYME A; THIOLESTER HYDROLASES; TIME FACTORS;

EID: 84886949159     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3526     Document Type: Article

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