Metabolomic profiling for biomarker discovery in pancreatic cancer

International Journal of Mass Spectrometry

Volumn 310, Issue , 2012, Pages 44-51

  Kaur, Prabhjit ^a   Sheikh, Kathryn ^a   Kirilyuk, Alexander ^a   Kirilyuk, Ksenia ^a   Singh, Rajbir ^a   Ressom, Habtom W ^a   Cheema, Amrita K ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

Biomarkers; LCMS; Metabolomics; Pancreatic cancer; Tissue extraction

Indexed keywords

EID: 84855213193     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2011.11.005     Document Type: Article

References (24)

1. S.R. Hamilton, and L.A. Aaltonen World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of the Digestive System 2000 IARC Press Lyon
2. I. Grantzdorffer, S. Carl-McGrath, M.P. Ebert, and C. Rocken Proteomics of pancreatic cancer Pancreas 36 4 2008 329 336 (Pubitemid 351591573)
3. R. Brand The diagnosis of pancreatic cancer Cancer J. 7 4 2001 287 297
4. J.K. Stratford, D.J. Bentrem, J.M. Anderson, C. Fan, K.A. Volmar, J.S. Marron, E.D. Routh, L.S. Caskey, J.C. Samuel, C.J. Der, L.B. Thorne, B.F. Calvo, H.J. Kim, M.S. Talamonti, C.A. Iacobuzio-Donahue, M.A. Hollingsworth, C.M. Perou, and J.J. Yeh A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma PLoS Med. 7 7 2010 e1000307
5. J. Wang, J. Chen, P. Chang, A. LeBlanc, D. Li, J.L. Abbruzzesse, M.L. Frazier, A.M. Killary, and S. Sen MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease Cancer Prev. Res. (Phila Pa) 2 9 2009 807 813
6. Y. Rong, D. Jin, C. Hou, J. Hu, W. Wu, X. Ni, D. Wang, and W. Lou Proteomics analysis of serum protein profiling in pancreatic cancer patients by DIGE: up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2 BMC Gastroenterol. 10 2010 68
7. S. Tonack, M. Aspinall-O'Dea, J.P. Neoptolemos, and E. Costello Pancreatic cancer: proteomic approaches to a challenging disease Pancreatology 9 5 2009 567 576
8. N. Blow Metabolomics: biochemistry's new look Nature 455 7213 2008 697 700
9. J.K. Nicholson, and J.C. Lindon Systems biology: metabonomics Nature 455 7216 2008 1054 1056
10. T.F. Bathen, L.R. Jensen, B. Sitter, H.E. Fjosne, J. Halgunset, D.E. Axelson, I.S. Gribbestad, and S. Lundgren MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status Breast Cancer Res. Treat. 104 2 2007 181 189 (Pubitemid 47086272)
11. A. Sreekumar, L.M. Poisson, T.M. Rajendiran, A.P. Khan, Q. Cao, J. Yu, B. Laxman, R. Mehra, R.J. Lonigro, Y. Li, M.K. Nyati, A. Ahsan, S. Kalyana-Sundaram, B. Han, X. Cao, J. Byun, G.S. Omenn, D. Ghosh, S. Pennathur, D.C. Alexander, A. Berger, J.R. Shuster, J.T. Wei, S. Varambally, C. Beecher, and A.M. Chinnaiyan Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression Nature 457 7231 2009 910 914
12. F. Sullentrop, D. Moka, S. Neubauer, G. Haupt, U. Engelmann, J. Hahn, and H. Schicha 31P NMR spectroscopy of blood plasma: determination and quantification of phospholipid classes in patients with renal cell carcinoma NMR Biomed. 15 1 2002 60 68 (Pubitemid 34177169)
13. B.J. Olson, J. Markwell, Assays for determination of protein concentration, Curr. Protoc. Pharmacol., 2007, Appendix 3, 3A.
14. R.S. Varghese, A. Cheema, P. Cheema, M. Bourbeau, L. Tuli, B. Zhou, M. Jung, A. Dritschilo, and H.W. Ressom Analysis of LC-MS data for characterizing the metabolic changes in response to radiation J. Proteome Res. 9 5 2010 2786 2793
15. I. Noda Scaling techniques to enhance two-dimensional correlation spectra J. Mol. Struct. 883-884 2008 216 227
16. J.W.S. Trygg Orthogonal projections to latent structures (O-PLS) J. Chemom. 16 2002 119 128
17. L. Breiman Random forests Mach. Learn. 45 2001 5 32 (Pubitemid 32933532)
18. Q. Cui, I.A. Lewis, A.D. Hegeman, M.E. Anderson, J. Li, C.F. Schulte, W.M. Westler, H.R. Eghbalnia, M.R. Sussman, and J.L. Markley Metabolite identification via the Madison Metabolomics Consortium Database Nat. Biotechnol. 26 2 2008 162 164 (Pubitemid 351225941)
19. D.S. Wishart, C. Knox, A.C. Guo, R. Eisner, N. Young, B. Gautam, D.D. Hau, N. Psychogios, E. Dong, S. Bouatra, R. Mandal, I. Sinelnikov, J. Xia, L. Jia, J.A. Cruz, E. Lim, C.A. Sobsey, S. Shrivastava, P. Huang, P. Liu, L. Fang, J. Peng, R. Fradette, D. Cheng, D. Tzur, M. Clements, A. Lewis, A. De Souza, A. Zuniga, M. Dawe, Y. Xiong, D. Clive, R. Greiner, A. Nazyrova, R. Shaykhutdinov, L. Li, H.J. Vogel, and I. Forsythe HMDB: a knowledgebase for the human metabolome Nucleic Acids Res. 37 2009 D603 D610 (Database issue)
20. J.B. Tyburski, A.D. Patterson, K.W. Krausz, J. Slavik, A.J. Fornace Jr., F.J. Gonzalez, and J.R. Idle Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice Radiat. Res. 172 1 2009 42 57
21. J. Kasapovic, S. Pejic, V. Stojiljkovic, A. Todorovic, L. Radosevic-Jelic, Z.S. Saicic, and S.B. Pajovic Antioxidant status and lipid peroxidation in the blood of breast cancer patients of different ages after chemotherapy with 5-fluorouracil, doxorubicin and cyclophosphamide Clin. Biochem. 43 2010 1287 1293
22. S. Srivastava, R. Roy, S. Singh, P. Kumar, D. Dalela, S.N. Sankhwar, A. Goel, and A.A. Sonkar Taurine - a possible fingerprint biomarker in non-muscle invasive bladder cancer: a pilot study by 1H NMR spectroscopy Cancer Biomark. 6 1 2010 11 20
23. S. Urayama, W. Zou, K. Brooks, and V. Tolstikov Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer Rapid Commun. Mass Spectrom. 24 5 2010 613 620
24. D.H. Williamson, P. Lund, and H.A. Krebs The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver Biochem. J. 103 2 1967 514 527