Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37330-37339

  Greaves, Jennifer ^a   Lemonidis, Kimon ^a   Gorleku, Oforiwa A ^a   Cruchaga, Carlos ^b   Grefen, Christopher ^c   Chamberlain, Luke H ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN SAMPLE; CELL LINES; CEROID LIPOFUSCINOSIS; PALMITOYLATION; PROTEIN MUTANTS;

ACYLATION; AMINO ACIDS; CELL CULTURE; NEURONS; PROTEINS;

AGGREGATES;

ACYLTRANSFERASE; CYSTEINE STRING PROTEIN; CYSTEINE STRING PROTEIN ALPHA; DODECYL SULFATE SODIUM; PALMITIC ACID; PALMITOYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN LEVEL; BRAIN TISSUE; CONTROLLED STUDY; DNAJC5 GENE; ENZYME ACTIVITY; GENE; GENE IDENTIFICATION; GENE MUTATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTATIONAL ANALYSIS; NEURONAL CEROID LIPOFUSCINOSIS; NEUROSECRETORY CELL; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ACYLTRANSFERASES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CEREBRAL CORTEX; HEK293 CELLS; HSP40 HEAT-SHOCK PROTEINS; HUMANS; LIPOYLATION; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NEURONAL CEROID-LIPOFUSCINOSES; PC12 CELLS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RATS;

EID: 84868261172     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.389098     Document Type: Article

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