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Volumn 18, Issue 21-22, 2013, Pages 1052-1066

Molecular imaging in the development of a novel treatment paradigm for glioblastoma (GBM): An integrated multidisciplinary commentary

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; ALPHA METHYL TYROSINE I 123; BEVACIZUMAB; BYK 191023; CEDIRANIB; CHOLINE C 11; ENZASTAURIN; ERLOTINIB; EVEROLIMUS; FLUCICLATIDE F 18; FLUORO 3 DEOXYTHYMIDINE F 18; FLUORODEOXYGLUCOSE F 18; FLUOROETHYL L TYROSINE F 18; GADOLINIUM PENTETATE; GALACTO ARGININE GLYCINE ASPARTIC ACID F 18; GEFITINIB; METHIONINE C 11; RADIOPHARMACEUTICAL AGENT; SORAFENIB; SUNITINIB; SUPERPARAMAGNETIC IRON OXIDE; TEMSIROLIMUS; THALLIUM 201; UNCLASSIFIED DRUG;

EID: 84886948024     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2013.06.004     Document Type: Review
Times cited : (16)

References (104)
  • 1
    • 84886947854 scopus 로고    scopus 로고
    • National Cancer Institute at the National Institutes of Heath accessed June 2013
    • National Cancer Institute at the National Institutes of Heath. Available at: http://www.cancer.gov/, accessed June 2013.
  • 2
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • D.N. Louis The 2007 WHO classification of tumours of the central nervous system Acta Neuropathol. 114 2007 97 109
    • (2007) Acta Neuropathol. , vol.114 , pp. 97-109
    • Louis, D.N.1
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • R. Stupp Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial Lancet Oncol. 10 2009 459 466
    • (2009) Lancet Oncol. , vol.10 , pp. 459-466
    • Stupp, R.1
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 37049025568 scopus 로고    scopus 로고
    • Advanced MRI in the management of adult gliomas
    • M.D. Jenkinson Advanced MRI in the management of adult gliomas Br. J. Neurosurg. 21 2007 550 561
    • (2007) Br. J. Neurosurg. , vol.21 , pp. 550-561
    • Jenkinson, M.D.1
  • 6
    • 34249794860 scopus 로고    scopus 로고
    • Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma
    • P. McConville Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma Clin. Cancer Res. 13 2007 2897 2904
    • (2007) Clin. Cancer Res. , vol.13 , pp. 2897-2904
    • McConville, P.1
  • 7
    • 0023939369 scopus 로고
    • MR contrast enhancement of intracranial lesions with Gd-DTPA
    • J.R. Hesselink, and G.A. Press MR contrast enhancement of intracranial lesions with Gd-DTPA Radiol. Clin. North Am. 26 1988 873 887
    • (1988) Radiol. Clin. North Am. , vol.26 , pp. 873-887
    • Hesselink, J.R.1    Press, G.A.2
  • 8
    • 35348987493 scopus 로고    scopus 로고
    • Advanced MRI of adult brain tumors
    • G.S. Young Advanced MRI of adult brain tumors Neurol. Clin. 25 2007 947 973
    • (2007) Neurol. Clin. , vol.25 , pp. 947-973
    • Young, G.S.1
  • 9
    • 77749268088 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors
    • A. Server Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors Acta Radiol. 51 2010 316 325
    • (2010) Acta Radiol. , vol.51 , pp. 316-325
    • Server, A.1
  • 10
    • 34250792105 scopus 로고    scopus 로고
    • Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging
    • S. Cha Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging AJNR Am. J. Neuroradiol. 28 2007 1078 1084
    • (2007) AJNR Am. J. Neuroradiol. , vol.28 , pp. 1078-1084
    • Cha, S.1
  • 11
    • 77955101935 scopus 로고    scopus 로고
    • Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab
    • R.E. Port Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors: Application to glioblastoma treated with bevacizumab Magn. Reson. Med. 64 2010 408 417
    • (2010) Magn. Reson. Med. , vol.64 , pp. 408-417
    • Port, R.E.1
  • 12
    • 68449096237 scopus 로고    scopus 로고
    • Arterial spin-labeled perfusion MRI in basic and clinical neuroscience
    • J.A. Detre Arterial spin-labeled perfusion MRI in basic and clinical neuroscience Curr. Opin. Neurol. 22 2009 348 355
    • (2009) Curr. Opin. Neurol. , vol.22 , pp. 348-355
    • Detre, J.A.1
  • 13
    • 77954730533 scopus 로고    scopus 로고
    • Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib
    • E.R. Gerstner Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib Neuro Oncol. 12 2010 466 472
    • (2010) Neuro Oncol. , vol.12 , pp. 466-472
    • Gerstner, E.R.1
  • 14
    • 75049085358 scopus 로고    scopus 로고
    • Diffusion tensor-based tumor infiltration index cannot discriminate vasogenic edema from tumor-infiltrated edema
    • M. Kinoshita Diffusion tensor-based tumor infiltration index cannot discriminate vasogenic edema from tumor-infiltrated edema J. Neurooncol. 96 2010 409 415
    • (2010) J. Neurooncol. , vol.96 , pp. 409-415
    • Kinoshita, M.1
  • 15
    • 1842535161 scopus 로고    scopus 로고
    • Evoked-cerebral blood oxygenation changes in false-negative activations in BOLD contrast functional MRI of patients with brain tumors
    • N. Fujiwara Evoked-cerebral blood oxygenation changes in false-negative activations in BOLD contrast functional MRI of patients with brain tumors Neuroimage 21 2004 1464 1471
    • (2004) Neuroimage , vol.21 , pp. 1464-1471
    • Fujiwara, N.1
  • 16
    • 80052714649 scopus 로고    scopus 로고
    • Molecular imaging of gliomas with PET: Opportunities and limitations
    • C. la Fougere Molecular imaging of gliomas with PET: opportunities and limitations Neuro Oncol. 13 2011 806 819
    • (2011) Neuro Oncol. , vol.13 , pp. 806-819
    • La Fougere, C.1
  • 17
    • 46749098311 scopus 로고    scopus 로고
    • 11C-choline positron-emission tomography
    • 11C-choline positron-emission tomography AJNR Am. J. Neuroradiol. 29 2008 1176 1182
    • (2008) AJNR Am. J. Neuroradiol. , vol.29 , pp. 1176-1182
    • Kato, T.1
  • 18
    • 84874645409 scopus 로고    scopus 로고
    • Tryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlates
    • D.O. Kamson Tryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlates J. Neurooncol. 112 2013 121 132
    • (2013) J. Neurooncol. , vol.112 , pp. 121-132
    • Kamson, D.O.1
  • 19
    • 72949111978 scopus 로고    scopus 로고
    • Volumetry of [(11)C]-methionine PET uptake and MRI contrast enhancement in patients with recurrent glioblastoma multiforme
    • N. Galldiks Volumetry of [(11)C]-methionine PET uptake and MRI contrast enhancement in patients with recurrent glioblastoma multiforme Eur. J. Nucl. Med. Mol. Imaging 37 2010 84 92
    • (2010) Eur. J. Nucl. Med. Mol. Imaging , vol.37 , pp. 84-92
    • Galldiks, N.1
  • 20
    • 84856802355 scopus 로고    scopus 로고
    • 18F-FET) PET for the differential diagnosis of primary brain tumor: A systematic review and Metaanalysis
    • 18F-FET) PET for the differential diagnosis of primary brain tumor: a systematic review and Metaanalysis J. Nucl. Med. 53 2012 207 214
    • (2012) J. Nucl. Med. , vol.53 , pp. 207-214
    • Dunet, V.1
  • 21
    • 0031790264 scopus 로고    scopus 로고
    • Imaging proliferation in vivo with [F-18]FLT and positron emission tomography
    • A.F. Shields Imaging proliferation in vivo with [F-18]FLT and positron emission tomography Nat. Med. 4 1998 1334 1336
    • (1998) Nat. Med. , vol.4 , pp. 1334-1336
    • Shields, A.F.1
  • 22
    • 84862587185 scopus 로고    scopus 로고
    • (18)F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas
    • K. Hirata (18)F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas Eur. J. Nucl. Med. Mol. Imaging 39 2012 760 770
    • (2012) Eur. J. Nucl. Med. Mol. Imaging , vol.39 , pp. 760-770
    • Hirata, K.1
  • 23
    • 79952784609 scopus 로고    scopus 로고
    • 18F-labeled alphaVbeta3-integrin and alphaV beta5-integrin imaging agent
    • 18F-labeled alphaVbeta3-integrin and alphaV beta5-integrin imaging agent J. Nucl. Med. 52 2011 424 430
    • (2011) J. Nucl. Med. , vol.52 , pp. 424-430
    • Battle, M.R.1
  • 24
    • 53749108252 scopus 로고    scopus 로고
    • Small-animal SPECT and SPECT/CT: Important tools for preclinical investigation
    • B.L. Franc Small-animal SPECT and SPECT/CT: important tools for preclinical investigation J. Nucl. Med. 49 2008 1651 1663
    • (2008) J. Nucl. Med. , vol.49 , pp. 1651-1663
    • Franc, B.L.1
  • 25
    • 33745842549 scopus 로고    scopus 로고
    • Thallium-201 SPECT in prognostic assessment of malignant gliomas treated with postoperative radiotherapy
    • T. Semba Thallium-201 SPECT in prognostic assessment of malignant gliomas treated with postoperative radiotherapy Ann. Nucl. Med. 20 2006 287 294
    • (2006) Ann. Nucl. Med. , vol.20 , pp. 287-294
    • Semba, T.1
  • 26
    • 58149204031 scopus 로고    scopus 로고
    • Direct comparison of thallium-201 and technetium-99 m MIBI SPECT of a glioma by receiver operating characteristic analysis
    • Y. Shibata Direct comparison of thallium-201 and technetium-99 m MIBI SPECT of a glioma by receiver operating characteristic analysis J. Clin. Neurosci. 16 2009 264 269
    • (2009) J. Clin. Neurosci. , vol.16 , pp. 264-269
    • Shibata, Y.1
  • 27
    • 34347381319 scopus 로고    scopus 로고
    • 123I-IMT SPECT for evaluation of the response to radiation therapy in high grade gliomas: A feasibility study
    • D. Kuczer 123I-IMT SPECT for evaluation of the response to radiation therapy in high grade gliomas: a feasibility study Br. J. Radiol. 80 2007 274 278
    • (2007) Br. J. Radiol. , vol.80 , pp. 274-278
    • Kuczer, D.1
  • 28
    • 16544376798 scopus 로고    scopus 로고
    • Noninvasive real-time in vivo bioluminescent imaging of gene expression and of tumor progression and metastasis
    • C.W. Lowik Noninvasive real-time in vivo bioluminescent imaging of gene expression and of tumor progression and metastasis Ernst Schering Res. Found. Workshop 49 2005 193 227
    • (2005) Ernst Schering Res. Found. Workshop , vol.49 , pp. 193-227
    • Lowik, C.W.1
  • 29
    • 0034486139 scopus 로고    scopus 로고
    • Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging
    • A. Rehemtulla Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging Neoplasia 2 2000 491 495
    • (2000) Neoplasia , vol.2 , pp. 491-495
    • Rehemtulla, A.1
  • 30
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • R. Weissleder, and M.J. Pittet Imaging in the era of molecular oncology Nature 452 2008 580 589
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 31
    • 33750971995 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model
    • A.R. Hsu In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model Mol. Imaging Biol. 8 2006 315 323
    • (2006) Mol. Imaging Biol. , vol.8 , pp. 315-323
    • Hsu, A.R.1
  • 32
    • 33645986455 scopus 로고    scopus 로고
    • Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
    • W. Stummer Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial Lancet Oncol. 7 2006 392 401
    • (2006) Lancet Oncol. , vol.7 , pp. 392-401
    • Stummer, W.1
  • 33
    • 84855774309 scopus 로고    scopus 로고
    • Comparison of F-18 FDG and C-11 methionine PET/CT for the evaluation of recurrent primary brain tumors
    • M. Tripathi Comparison of F-18 FDG and C-11 methionine PET/CT for the evaluation of recurrent primary brain tumors Clin. Nucl. Med. 37 2012 158 163
    • (2012) Clin. Nucl. Med. , vol.37 , pp. 158-163
    • Tripathi, M.1
  • 34
    • 60549091544 scopus 로고    scopus 로고
    • Multimodality imaging: An update on PET/CT technology
    • O. Mawlawi, and D.W. Townsend Multimodality imaging: an update on PET/CT technology Eur. J. Nucl. Med. Mol. Imaging 36 Suppl. 1 2009 15 29
    • (2009) Eur. J. Nucl. Med. Mol. Imaging , vol.36 , Issue.SUPPL. 1 , pp. 15-29
    • Mawlawi, O.1    Townsend, D.W.2
  • 35
    • 32244445536 scopus 로고    scopus 로고
    • Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: Correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect
    • O. Szentirmai Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect Neurosurgery 58 2006 365 372
    • (2006) Neurosurgery , vol.58 , pp. 365-372
    • Szentirmai, O.1
  • 36
    • 70349653907 scopus 로고    scopus 로고
    • Measuring brain tumor growth: Combined bioluminescence imaging-magnetic resonance imaging strategy
    • S.C. Jost Measuring brain tumor growth: combined bioluminescence imaging-magnetic resonance imaging strategy Mol. Imaging 8 2009 245 253
    • (2009) Mol. Imaging , vol.8 , pp. 245-253
    • Jost, S.C.1
  • 37
    • 70349784211 scopus 로고    scopus 로고
    • Optical imaging of Cerenkov light generation from positron-emitting radiotracers
    • R. Robertson Optical imaging of Cerenkov light generation from positron-emitting radiotracers Phys. Med. Biol. 54 2009 355 365
    • (2009) Phys. Med. Biol. , vol.54 , pp. 355-365
    • Robertson, R.1
  • 38
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • H.S. Friedman Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma J. Clin. Oncol. 27 2009 4733 4740
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4733-4740
    • Friedman, H.S.1
  • 39
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • T.N. Kreisl Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma J. Clin. Oncol. 27 2009 740 745
    • (2009) J. Clin. Oncol. , vol.27 , pp. 740-745
    • Kreisl, T.N.1
  • 40
    • 20144370978 scopus 로고    scopus 로고
    • AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
    • S.R. Wedge AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer Cancer Res. 65 2005 4389 4400
    • (2005) Cancer Res. , vol.65 , pp. 4389-4400
    • Wedge, S.R.1
  • 41
    • 33746591262 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors of vascular endothelial growth factor receptors in clinical trials: Current status and future directions
    • A. Morabito Tyrosine kinase inhibitors of vascular endothelial growth factor receptors in clinical trials: current status and future directions Oncologist 11 2006 753 764
    • (2006) Oncologist , vol.11 , pp. 753-764
    • Morabito, A.1
  • 42
    • 77950833182 scopus 로고    scopus 로고
    • Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3
    • F. Yang Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3 Mol. Cancer Ther. 9 2010 953 962
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 953-962
    • Yang, F.1
  • 43
    • 79959795987 scopus 로고    scopus 로고
    • Phase II study of sunitinib malate in patients with recurrent high-grade glioma
    • B. Neyns Phase II study of sunitinib malate in patients with recurrent high-grade glioma J. Neurooncol. 103 2011 491 501
    • (2011) J. Neurooncol. , vol.103 , pp. 491-501
    • Neyns, B.1
  • 44
    • 77955363593 scopus 로고    scopus 로고
    • Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme
    • J.D. Hainsworth Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme Cancer 116 2010 3663 3669
    • (2010) Cancer , vol.116 , pp. 3663-3669
    • Hainsworth, J.D.1
  • 45
    • 79955831459 scopus 로고    scopus 로고
    • Antiangiogenic therapy for patients with glioblastoma: Current challenges in imaging and future directions
    • M.S. Ahluwalia, and P.Y. Wen Antiangiogenic therapy for patients with glioblastoma: current challenges in imaging and future directions Expert Rev. Anticancer Ther. 11 2011 653 656
    • (2011) Expert Rev. Anticancer Ther. , vol.11 , pp. 653-656
    • Ahluwalia, M.S.1    Wen, P.Y.2
  • 46
    • 79951606981 scopus 로고    scopus 로고
    • Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma
    • E. Essock-Burns Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma Neuro Oncol. 13 2011 119 131
    • (2011) Neuro Oncol. , vol.13 , pp. 119-131
    • Essock-Burns, E.1
  • 47
    • 67650463119 scopus 로고    scopus 로고
    • A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients
    • A.G. Sorensen A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients Cancer Res. 69 2009 5296 5300
    • (2009) Cancer Res. , vol.69 , pp. 5296-5300
    • Sorensen, A.G.1
  • 48
    • 77649224700 scopus 로고    scopus 로고
    • Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity
    • B.M. Ellingson Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity J. Magn. Reson. Imaging 31 2010 538 548
    • (2010) J. Magn. Reson. Imaging , vol.31 , pp. 538-548
    • Ellingson, B.M.1
  • 49
    • 0034694661 scopus 로고    scopus 로고
    • Diffusion magnetic resonance imaging: An early surrogate marker of therapeutic efficacy in brain tumors
    • T.L. Chenevert Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors J. Natl. Cancer Inst. 92 2000 2029 2036
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 2029-2036
    • Chenevert, T.L.1
  • 50
    • 84355162260 scopus 로고    scopus 로고
    • Nonlinear registration of diffusion-weighted images improves clinical sensitivity of functional diffusion maps in recurrent glioblastoma treated with bevacizumab
    • B.M. Ellingson Nonlinear registration of diffusion-weighted images improves clinical sensitivity of functional diffusion maps in recurrent glioblastoma treated with bevacizumab Magn. Reson. Med. 67 2011 237 245
    • (2011) Magn. Reson. Med. , vol.67 , pp. 237-245
    • Ellingson, B.M.1
  • 51
    • 66249097780 scopus 로고    scopus 로고
    • Quantitative metrics of net proliferation and invasion link biological aggressiveness assessed by MRI with hypoxia assessed by FMISO-PET in newly diagnosed glioblastomas
    • M.D. Szeto Quantitative metrics of net proliferation and invasion link biological aggressiveness assessed by MRI with hypoxia assessed by FMISO-PET in newly diagnosed glioblastomas Cancer Res. 69 2009 4502 4509
    • (2009) Cancer Res. , vol.69 , pp. 4502-4509
    • Szeto, M.D.1
  • 52
    • 36048955738 scopus 로고    scopus 로고
    • 18F] fluorothymidine positron emission tomography: A pilot study
    • 18F] fluorothymidine positron emission tomography: a pilot study J. Clin. Oncol. 25 2007 4714 4721
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4714-4721
    • Chen, W.1
  • 53
    • 79958148395 scopus 로고    scopus 로고
    • 18F-fluoroethyl)-L-tyrosine PET predicts failure of antiangiogenic treatment in patients with recurrent high-grade glioma
    • 18F-fluoroethyl)-L-tyrosine PET predicts failure of antiangiogenic treatment in patients with recurrent high-grade glioma J. Nucl. Med. 52 2011 856 864
    • (2011) J. Nucl. Med. , vol.52 , pp. 856-864
    • Hutterer, M.1
  • 54
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • G. Bergers, and D. Hanahan Modes of resistance to anti-angiogenic therapy Nat. Rev. Cancer 8 2008 592 603
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 55
    • 84863754907 scopus 로고    scopus 로고
    • VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
    • K.V. Lu VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex Cancer Cell 22 2012 21 35
    • (2012) Cancer Cell , vol.22 , pp. 21-35
    • Lu, K.V.1
  • 56
    • 77149165396 scopus 로고    scopus 로고
    • Therapeutic targeting of EGFR in malignant gliomas
    • F. Ye Therapeutic targeting of EGFR in malignant gliomas Expert Opin. Ther. Targets 14 2010 303 316
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 303-316
    • Ye, F.1
  • 57
    • 77953617053 scopus 로고    scopus 로고
    • Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
    • D.M. Peereboom Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme J. Neurooncol. 98 2010 93 99
    • (2010) J. Neurooncol. , vol.98 , pp. 93-99
    • Peereboom, D.M.1
  • 58
    • 79955582712 scopus 로고    scopus 로고
    • Phase II evaluation of gefitinib in patients with newly diagnosed Grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074
    • J.H. Uhm Phase II evaluation of gefitinib in patients with newly diagnosed Grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074 Int. J. Radiat. Oncol. Biol. Phys. 80 2011 347 353
    • (2011) Int. J. Radiat. Oncol. Biol. Phys. , vol.80 , pp. 347-353
    • Uhm, J.H.1
  • 59
    • 66249149058 scopus 로고    scopus 로고
    • EGFRvIII and DNA double-strand break repair: A molecular mechanism for radioresistance in glioblastoma
    • B. Mukherjee EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma Cancer Res. 69 2009 4252 4259
    • (2009) Cancer Res. , vol.69 , pp. 4252-4259
    • Mukherjee, B.1
  • 60
    • 20244388526 scopus 로고    scopus 로고
    • Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR
    • C. Panousis Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR Br. J. Cancer 92 2005 1069 1077
    • (2005) Br. J. Cancer , vol.92 , pp. 1069-1077
    • Panousis, C.1
  • 61
    • 77953924458 scopus 로고    scopus 로고
    • Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806
    • F.T. Lee Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806 J. Nucl. Med. 51 2010 967 972
    • (2010) J. Nucl. Med. , vol.51 , pp. 967-972
    • Lee, F.T.1
  • 62
    • 80051682063 scopus 로고    scopus 로고
    • Immuno-PET of cancer: A revival of antibody imaging
    • O.C. Boerman, and W.J. Oyen Immuno-PET of cancer: a revival of antibody imaging J. Nucl. Med. 52 2011 1171 1172
    • (2011) J. Nucl. Med. , vol.52 , pp. 1171-1172
    • Boerman, O.C.1    Oyen, W.J.2
  • 63
    • 77955388676 scopus 로고    scopus 로고
    • EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma
    • C.G. Hadjipanayis EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma Cancer Res. 70 2010 6303 6312
    • (2010) Cancer Res. , vol.70 , pp. 6303-6312
    • Hadjipanayis, C.G.1
  • 64
    • 84860380115 scopus 로고    scopus 로고
    • Use of magnetic perfusion-weighted imaging to determine epidermal growth factor receptor variant III expression in glioblastoma
    • E.S. Tykocinski Use of magnetic perfusion-weighted imaging to determine epidermal growth factor receptor variant III expression in glioblastoma Neuro Oncol. 14 2012 613 623
    • (2012) Neuro Oncol. , vol.14 , pp. 613-623
    • Tykocinski, E.S.1
  • 65
    • 79953298958 scopus 로고    scopus 로고
    • Next-generation mTOR inhibitors in clinical oncology: How pathway complexity informs therapeutic strategy
    • S.A. Wander Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy J. Clin. Invest. 121 2011 1231 1241
    • (2011) J. Clin. Invest. , vol.121 , pp. 1231-1241
    • Wander, S.A.1
  • 66
    • 78149479091 scopus 로고    scopus 로고
    • MTOR signaling in glioblastoma: Lessons learned from bench to bedside
    • D. Akhavan mTOR signaling in glioblastoma: lessons learned from bench to bedside Neuro Oncol. 12 2010 882 889
    • (2010) Neuro Oncol. , vol.12 , pp. 882-889
    • Akhavan, D.1
  • 67
    • 79953709986 scopus 로고    scopus 로고
    • Targeting the mTOR kinase domain: The second generation of mTOR inhibitors
    • Y.J. Zhang Targeting the mTOR kinase domain: the second generation of mTOR inhibitors Drug Discov. Today 16 2011 325 331
    • (2011) Drug Discov. Today , vol.16 , pp. 325-331
    • Zhang, Y.J.1
  • 68
    • 50349083186 scopus 로고    scopus 로고
    • Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma
    • L.H. Wei Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma Clin. Cancer Res. 14 2008 3416 3426
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3416-3426
    • Wei, L.H.1
  • 69
    • 81155160947 scopus 로고    scopus 로고
    • 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma
    • 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma Neuroimage 59 2012 193 201
    • (2012) Neuroimage , vol.59 , pp. 193-201
    • Chaumeil, M.M.1
  • 70
    • 84861844809 scopus 로고    scopus 로고
    • 13C MR spectroscopic imaging
    • 13C MR spectroscopic imaging Br. J. Radiol. 85 2012 697 708
    • (2012) Br. J. Radiol. , vol.85 , pp. 697-708
    • Brindle, K.1
  • 71
    • 79251575938 scopus 로고    scopus 로고
    • Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma
    • K.L. Pitter Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma PLoS ONE 6 2011 e14545
    • (2011) PLoS ONE , vol.6 , pp. 14545
    • Pitter, K.L.1
  • 72
    • 27844477765 scopus 로고    scopus 로고
    • Combining cytotoxic and immune-mediated gene therapy to treat brain tumors
    • J.F. Curtin Combining cytotoxic and immune-mediated gene therapy to treat brain tumors Curr. Top. Med. Chem. 5 2005 1151 1170
    • (2005) Curr. Top. Med. Chem. , vol.5 , pp. 1151-1170
    • Curtin, J.F.1
  • 73
    • 52149084321 scopus 로고    scopus 로고
    • Searching for a cure: Gene therapy for glioblastoma
    • P. Dent Searching for a cure: gene therapy for glioblastoma Cancer Biol. Ther. 7 2008 1335 1340
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1335-1340
    • Dent, P.1
  • 74
    • 0033222263 scopus 로고    scopus 로고
    • HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: Part I. HSV-1 structure, replication and pathogenesis
    • A. Jacobs HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis Neoplasia 1 1999 387 401
    • (1999) Neoplasia , vol.1 , pp. 387-401
    • Jacobs, A.1
  • 75
    • 0035300468 scopus 로고    scopus 로고
    • Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo
    • A. Jacobs Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo Cancer Res. 61 2001 2983 2995
    • (2001) Cancer Res. , vol.61 , pp. 2983-2995
    • Jacobs, A.1
  • 76
    • 33644659341 scopus 로고    scopus 로고
    • A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model
    • F. Niola A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model Cancer Biol. Ther. 5 2006 174 179
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 174-179
    • Niola, F.1
  • 77
    • 38649141851 scopus 로고    scopus 로고
    • Immunization against the transgene but not the TetON switch reduces expression from gutless adenoviral vectors in the brain
    • W. Xiong Immunization against the transgene but not the TetON switch reduces expression from gutless adenoviral vectors in the brain Mol. Ther. 16 2008 343 351
    • (2008) Mol. Ther. , vol.16 , pp. 343-351
    • Xiong, W.1
  • 78
    • 73149094257 scopus 로고    scopus 로고
    • Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth
    • J. George Combination of taxol and Bcl-2 siRNA induces apoptosis in human glioblastoma cells and inhibits invasion, angiogenesis and tumour growth J. Cell. Mol. Med. 13 2009 4205 4218
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 4205-4218
    • George, J.1
  • 79
    • 33847728953 scopus 로고    scopus 로고
    • Imaging-guided gene therapy of experimental gliomas
    • A.H. Jacobs Imaging-guided gene therapy of experimental gliomas Cancer Res. 67 2007 1706 1715
    • (2007) Cancer Res. , vol.67 , pp. 1706-1715
    • Jacobs, A.H.1
  • 81
    • 41949137108 scopus 로고    scopus 로고
    • Switching on the lights for gene therapy
    • A. Winkeler Switching on the lights for gene therapy PLoS ONE 2 2007 e528
    • (2007) PLoS ONE , vol.2 , pp. 528
    • Winkeler, A.1
  • 82
    • 30644457691 scopus 로고    scopus 로고
    • Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
    • F. Colombo Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results Cancer Gene Ther. 12 2005 835 848
    • (2005) Cancer Gene Ther. , vol.12 , pp. 835-848
    • Colombo, F.1
  • 83
    • 0141870056 scopus 로고    scopus 로고
    • Imaging-guided convection-enhanced delivery and gene therapy of glioblastoma
    • J. Voges Imaging-guided convection-enhanced delivery and gene therapy of glioblastoma Annal. Neurol. 54 2003 479 487
    • (2003) Annal. Neurol. , vol.54 , pp. 479-487
    • Voges, J.1
  • 84
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • T. Reya Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1
  • 85
    • 67650079215 scopus 로고    scopus 로고
    • Tumor microvasculature supports proliferation and expansion of glioma-propagating cells
    • T. Borovski Tumor microvasculature supports proliferation and expansion of glioma-propagating cells Int. J. Cancer 125 2009 1222 1230
    • (2009) Int. J. Cancer , vol.125 , pp. 1222-1230
    • Borovski, T.1
  • 86
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • S. Bao Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 2006 756 760
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1
  • 87
    • 78650905948 scopus 로고    scopus 로고
    • Non-invasive in vivo imaging of tumor-associated CD133/prominin
    • C. Tsurumi Non-invasive in vivo imaging of tumor-associated CD133/prominin PLoS ONE 5 2010 e15605
    • (2010) PLoS ONE , vol.5 , pp. 15605
    • Tsurumi, C.1
  • 88
    • 79959969874 scopus 로고    scopus 로고
    • Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
    • C.E. Eyler Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2 Cell 146 2011 53 66
    • (2011) Cell , vol.146 , pp. 53-66
    • Eyler, C.E.1
  • 89
    • 75349105363 scopus 로고    scopus 로고
    • NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
    • X. Fan NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts Stem Cells 28 2010 5 16
    • (2010) Stem Cells , vol.28 , pp. 5-16
    • Fan, X.1
  • 90
    • 63849134637 scopus 로고    scopus 로고
    • Multimodal imaging of neural progenitor cell fate in rodents
    • Y. Waerzeggers Multimodal imaging of neural progenitor cell fate in rodents Mol. Imaging 7 2008 77 91
    • (2008) Mol. Imaging , vol.7 , pp. 77-91
    • Waerzeggers, Y.1
  • 91
    • 79951773437 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of cell tropism, trafficking mechanism, and therapeutic impact of human mesenchymal stem cells in a murine glioma model
    • L.Y. Chien In vivo magnetic resonance imaging of cell tropism, trafficking mechanism, and therapeutic impact of human mesenchymal stem cells in a murine glioma model Biomaterials 32 2011 3275 3284
    • (2011) Biomaterials , vol.32 , pp. 3275-3284
    • Chien, L.Y.1
  • 92
    • 80051516653 scopus 로고    scopus 로고
    • Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-A glioma model
    • T. Doucette Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model Neoplasia 13 2011 716 725
    • (2011) Neoplasia , vol.13 , pp. 716-725
    • Doucette, T.1
  • 93
    • 84856263167 scopus 로고    scopus 로고
    • Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas
    • T.M. Kauer Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas Nature Neurosci. 15 2012 197 204
    • (2012) Nature Neurosci. , vol.15 , pp. 197-204
    • Kauer, T.M.1
  • 94
    • 66849103743 scopus 로고    scopus 로고
    • Phase 0 clinical trials: An answer to drug development stagnation?
    • P.M. LoRusso Phase 0 clinical trials: an answer to drug development stagnation? J. Clin. Oncol. 27 2009 2586 2588
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2586-2588
    • Lorusso, P.M.1
  • 95
    • 0025281789 scopus 로고
    • Response criteria for phase II studies of supratentorial malignant glioma
    • D.R. MacDonald Response criteria for phase II studies of supratentorial malignant glioma J. Clin. Oncol. 8 1990 1277 1280
    • (1990) J. Clin. Oncol. , vol.8 , pp. 1277-1280
    • Macdonald, D.R.1
  • 96
    • 77951625266 scopus 로고    scopus 로고
    • Updated response assessment criteria for high-grade gliomas: Response assessment in neuro-oncology working group
    • P.Y. Wen Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group J. Clin. Oncol. 28 2010 1963 1972
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1963-1972
    • Wen, P.Y.1
  • 97
    • 79957571056 scopus 로고    scopus 로고
    • MicroPET/CT imaging of an orthotopic model of human glioblastoma multiforme and evaluation of pulsed low-dose irradiation
    • S.S. Park MicroPET/CT imaging of an orthotopic model of human glioblastoma multiforme and evaluation of pulsed low-dose irradiation Int. J. Radiat. Oncol. Biol. Phys. 80 2011 885 892
    • (2011) Int. J. Radiat. Oncol. Biol. Phys. , vol.80 , pp. 885-892
    • Park, S.S.1
  • 98
    • 67650033114 scopus 로고    scopus 로고
    • Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT
    • S. Nimmagadda Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT J. Nucl. Med. 50 2009 1124 1130
    • (2009) J. Nucl. Med. , vol.50 , pp. 1124-1130
    • Nimmagadda, S.1
  • 99
    • 78651338642 scopus 로고    scopus 로고
    • The value of 99mTc-tetrofosmin brain SPECT in predicting survival in patients with glioblastoma multiforme
    • G.A. Alexiou The value of 99mTc-tetrofosmin brain SPECT in predicting survival in patients with glioblastoma multiforme J. Nucl. Med. 51 2010 1923 1926
    • (2010) J. Nucl. Med. , vol.51 , pp. 1923-1926
    • Alexiou, G.A.1
  • 100
    • 35448942790 scopus 로고    scopus 로고
    • 18F] fluorodeoxyglucose PET in the follow-up of glioblastoma multiforme
    • 18F] fluorodeoxyglucose PET in the follow-up of glioblastoma multiforme J. Neurooncol. 84 2007 305 314
    • (2007) J. Neurooncol. , vol.84 , pp. 305-314
    • Potzi, C.1
  • 101
    • 84863422770 scopus 로고    scopus 로고
    • Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI
    • T. Viel Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI J. Nucl. Med. 53 7 2012 1135 1145
    • (2012) J. Nucl. Med. , vol.53 , Issue.7 , pp. 1135-1145
    • Viel, T.1
  • 102
    • 77953049771 scopus 로고    scopus 로고
    • Perfusion MRI of brain tumours: A comparative study of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast imaging
    • H. Jarnum Perfusion MRI of brain tumours: a comparative study of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast imaging Neuroradiology 52 2010 307 317
    • (2010) Neuroradiology , vol.52 , pp. 307-317
    • Jarnum, H.1
  • 103
    • 84859541317 scopus 로고    scopus 로고
    • Role of diffusion tensor magnetic resonance tractography in predicting the extent of resection in glioma surgery
    • A. Castellano Role of diffusion tensor magnetic resonance tractography in predicting the extent of resection in glioma surgery Neuro Oncol. 14 2012 192 202
    • (2012) Neuro Oncol. , vol.14 , pp. 192-202
    • Castellano, A.1
  • 104
    • 72449174017 scopus 로고    scopus 로고
    • 18F] Galacto-RGD positron emission tomography
    • 18F] Galacto-RGD positron emission tomography Neuro Oncol. 11 2009 861 870
    • (2009) Neuro Oncol. , vol.11 , pp. 861-870
    • Schnell, O.1


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