메뉴 건너뛰기




Volumn 15, Issue 2, 2012, Pages 197-204

Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84856263167     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3019     Document Type: Article
Times cited : (189)

References (50)
  • 1
    • 68049117331 scopus 로고    scopus 로고
    • Glioblastoma multiforme: A review of where we have been and where we are going
    • Adamson, C. et al. Glioblastoma multiforme: a review of where we have been and where we are going. Expert Opin. Investig. Drugs 18, 1061-1083 (2009).
    • (2009) Expert Opin. Investig. Drugs , vol.18 , pp. 1061-1083
    • Adamson, C.1
  • 2
    • 68149181745 scopus 로고    scopus 로고
    • Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy
    • Affronti, M.L. et al. Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy. Cancer 115, 3501-3511 (2009).
    • (2009) Cancer , vol.115 , pp. 3501-3511
    • Affronti, M.L.1
  • 3
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen, P.Y. & Kesari, S. Malignant gliomas in adults. N. Engl. J. Med. 359, 492-507 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 4
    • 35349028239 scopus 로고    scopus 로고
    • Advances in Brain Tumor Surgery
    • DOI 10.1016/j.ncl.2007.07.006, PII S0733861907000783, Brain Tumors in Adults
    • Asthagiri, A.R., Pouratian, N., Sherman, J., Ahmed, G. & Shaffrey, M.E. Advances in brain tumor surgery. Neurol. Clin. 25, 975-1003, viii-ix (2007). (Pubitemid 47600574)
    • (2007) Neurologic Clinics , vol.25 , Issue.4 , pp. 975-1003
    • Asthagiri, A.R.1    Pouratian, N.2    Sherman, J.3    Ahmed, G.4    Shaffrey, M.E.5
  • 5
    • 67649097904 scopus 로고    scopus 로고
    • Outcome of newly diagnosed glioblastoma patients treated by radiotherapy plus concomitant and adjuvant temozolomide: A long-term analysis
    • Erpolat, O.P. et al. Outcome of newly diagnosed glioblastoma patients treated by radiotherapy plus concomitant and adjuvant temozolomide: a long-term analysis. Tumori 95, 191-197 (2009).
    • (2009) Tumori , vol.95 , pp. 191-197
    • Erpolat, O.P.1
  • 6
    • 42349090207 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients
    • Minniti, G. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients. J. Neurooncol. 88, 97-103 (2008).
    • (2008) J. Neurooncol. , vol.88 , pp. 97-103
    • Minniti, G.1
  • 8
    • 34047260282 scopus 로고    scopus 로고
    • Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
    • DOI 10.1158/0008-5472.CAN-06-4102
    • Jain, R.K., Tong, R.T. & Munn, L.L. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res. 67, 2729-2735 (2007). (Pubitemid 46548961)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2729-2735
    • Jain, R.K.1    Tong, R.T.2    Munn, L.L.3
  • 9
    • 70350502604 scopus 로고    scopus 로고
    • Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors
    • Sarin, H. Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors. J. Transl. Med. 7, 77 (2009).
    • (2009) J. Transl. Med. , vol.7 , pp. 77
    • Sarin, H.1
  • 10
    • 40949093112 scopus 로고    scopus 로고
    • Therapeutic stem-cells for cancer treatment: Hopes and hurdles in tactical warfare
    • DOI 10.1016/S1470-2045(08)70099-8, PII S1470204508700998
    • Corsten, M.F. & Shah, K. Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare. Lancet Oncol. 9, 376-384 (2008). (Pubitemid 351411654)
    • (2008) The Lancet Oncology , vol.9 , Issue.4 , pp. 376-384
    • Corsten, M.F.1    Shah, K.2
  • 11
    • 80051678161 scopus 로고    scopus 로고
    • Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts
    • Balyasnikova, I.V., Ferguson, S.D., Han, Y., Liu, F. & Lesniak, M.S. Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts. Cancer Lett. 310, 148-159 (2011).
    • (2011) Cancer Lett. , vol.310 , pp. 148-159
    • Balyasnikova, I.V.1    Ferguson, S.D.2    Han, Y.3    Liu, F.4    Lesniak, M.S.5
  • 12
    • 0037115671 scopus 로고    scopus 로고
    • Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand
    • Ehtesham, M. et al. Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res. 62, 7170-7174 (2002). (Pubitemid 36025232)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7170-7174
    • Ehtesham, M.1    Kabos, P.2    Gutierrez, M.A.R.3    Chung, N.H.C.4    Griffith, T.S.5    Black, K.L.6    Yu, J.S.7
  • 13
    • 33745563200 scopus 로고    scopus 로고
    • Apoptosis in human glioblastoma cells produced using embryonic stem cell-derived astrocytes expressing tumor necrosis factor-related apoptosis-inducing ligand
    • Germano, I.M., Uzzaman, M., Benveniste, R.J., Zaurova, M. & Keller, G. Apoptosis in human glioblastoma cells produced using embryonic stem cell-derived astrocytes expressing tumor necrosis factor-related apoptosis-inducing ligand. J. Neurosurg. 105, 88-95 (2006). (Pubitemid 43979102)
    • (2006) Journal of Neurosurgery , vol.105 , Issue.1 , pp. 88-95
    • Germano, I.M.1    Uzzaman, M.2    Benveniste, R.J.3    Zaurova, M.4    Keller, G.5
  • 14
    • 70349849517 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy
    • Menon, L.G. et al. Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy. Stem Cells 27, 2320-2330 (2009).
    • (2009) Stem Cells , vol.27 , pp. 2320-2330
    • Menon, L.G.1
  • 15
    • 84860639631 scopus 로고    scopus 로고
    • Mesenchymal stem cells engineered for cancer therapy
    • doi:10.1016/j.addr.2011.06.010 29 June
    • Shah, K. Mesenchymal stem cells engineered for cancer therapy. Adv. Drug Deliv. Rev. doi:10.1016/j.addr.2011.06.010 (29 June 2011).
    • (2011) Adv. Drug Deliv. Rev.
    • Shah, K.1
  • 16
    • 70449461053 scopus 로고    scopus 로고
    • Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold
    • Pan, L., Ren, Y., Cui, F. & Xu, Q. Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold. J. Neurosci. Res. 87, 3207-3220 (2009).
    • (2009) J. Neurosci. Res. , vol.87 , pp. 3207-3220
    • Pan, L.1    Ren, Y.2    Cui, F.3    Xu, Q.4
  • 17
    • 0036842501 scopus 로고    scopus 로고
    • The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue
    • DOI 10.1038/nbt751
    • Park, K.I., Teng, Y.D. & Snyder, E.Y. The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue. Nat. Biotechnol. 20, 1111-1117 (2002). (Pubitemid 35285439)
    • (2002) Nature Biotechnology , vol.20 , Issue.11 , pp. 1111-1117
    • Park, K.I.1    Teng, Y.D.2    Snyder, E.Y.3
  • 20
    • 38449100741 scopus 로고    scopus 로고
    • Biomimetic material systems for neural progenitor cell-based therapy
    • DOI 10.2741/2721
    • Potter, W., Kalil, R.E. & Kao, W.J. Biomimetic material systems for neural progenitor cell-based therapy. Front. Biosci. 13, 806-821 (2008). (Pubitemid 351594730)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.3 , pp. 806-821
    • Potter, W.1    Kalil, R.E.2    Kao, W.J.3
  • 21
    • 56249143130 scopus 로고    scopus 로고
    • Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide
    • Hingtgen, S. et al. Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol. Cancer Ther. 7, 3575-3585 (2008).
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3575-3585
    • Hingtgen, S.1
  • 22
    • 43749114031 scopus 로고    scopus 로고
    • Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model
    • Shah, K. et al. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J. Neurosci. 28, 4406-4413 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 4406-4413
    • Shah, K.1
  • 23
    • 26444560914 scopus 로고    scopus 로고
    • S translation and TRAIL sensitivity in glioblastoma multiforme cells
    • DOI 10.1128/MCB.25.20.8809-8823.2005
    • Panner, A., James, C.D., Berger, M.S. & Pieper, R.O. mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. Mol. Cell. Biol. 25, 8809-8823 (2005). (Pubitemid 41429073)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.20 , pp. 8809-8823
    • Panner, A.1    James, C.D.2    Berger, M.S.3    Pieper, R.O.4
  • 24
    • 0032079348 scopus 로고    scopus 로고
    • APO2 ligand: A novel lethal weapon against malignant glioma?
    • DOI 10.1016/S0014-5793(98)00409-8, PII S0014579398004098
    • Rieger, J., Naumann, U., Glaser, T., Ashkenazi, A. & Weller, M. APO2 ligand: a novel lethal weapon against malignant glioma? FEBS Lett. 427, 124-128 (1998). (Pubitemid 28210109)
    • (1998) FEBS Letters , vol.427 , Issue.1 , pp. 124-128
    • Rieger, J.1    Naumann, U.2    Glaser, T.3    Ashkenazi, A.4    Weller, M.5
  • 25
    • 68949122336 scopus 로고    scopus 로고
    • Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection
    • Akbar, U. et al. Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection. J. Neurooncol. 94, 203-212 (2009).
    • (2009) J. Neurooncol. , vol.94 , pp. 203-212
    • Akbar, U.1
  • 26
    • 67349280964 scopus 로고    scopus 로고
    • Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models
    • de Oliveira, M.S. et al. Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models. J. Neurooncol. 93, 191-201 (2009).
    • (2009) J. Neurooncol. , vol.93 , pp. 191-201
    • De Oliveira, M.S.1
  • 27
    • 69249217640 scopus 로고    scopus 로고
    • Biomaterials for promoting brain protection, repair and regeneration
    • Orive, G., Anitua, E., Pedraz, J.L. & Emerich, D.F. Biomaterials for promoting brain protection, repair and regeneration. Nat. Rev. Neurosci. 10, 682-692 (2009).
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 682-692
    • Orive, G.1    Anitua, E.2    Pedraz, J.L.3    Emerich, D.F.4
  • 28
    • 69549117128 scopus 로고    scopus 로고
    • Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors
    • Xu, X., Yang, G., Zhang, H. & Prestwich, G.D. Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors. Prostaglandins Other Lipid Mediat. 89, 140-146 (2009).
    • (2009) Prostaglandins Other Lipid Mediat. , vol.89 , pp. 140-146
    • Xu, X.1    Yang, G.2    Zhang, H.3    Prestwich, G.D.4
  • 29
    • 39749098711 scopus 로고    scopus 로고
    • Cell Delivery Mechanisms for Tissue Repair
    • DOI 10.1016/j.stem.2008.02.005, PII S1934590908000696
    • Mooney, D.J. & Vandenburgh, H. Cell delivery mechanisms for tissue repair. Cell Stem Cell 2, 205-213 (2008). (Pubitemid 351298597)
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 205-213
    • Mooney, D.J.1    Vandenburgh, H.2
  • 30
    • 55049116156 scopus 로고    scopus 로고
    • Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography
    • Terrovitis, J. et al. Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography. J. Am. Coll. Cardiol. 52, 1652-1660 (2008).
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 1652-1660
    • Terrovitis, J.1
  • 31
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A. & Dixit, V.M. Death receptors: signaling and modulation. Science 281, 1305-1308 (1998). (Pubitemid 28406815)
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 32
    • 63849148548 scopus 로고    scopus 로고
    • Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
    • Sasportas, L.S. et al. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc. Natl. Acad. Sci. USA 106, 4822-4827 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4822-4827
    • Sasportas, L.S.1
  • 33
    • 77950978854 scopus 로고    scopus 로고
    • A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy
    • Hingtgen, S.D., Kasmieh, R., van de Water, J., Weissleder, R. & Shah, K. A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. Stem Cells 28, 832-841 (2010).
    • (2010) Stem Cells , vol.28 , pp. 832-841
    • Hingtgen, S.D.1    Kasmieh, R.2    Van De Water, J.3    Weissleder, R.4    Shah, K.5
  • 34
    • 80051686709 scopus 로고    scopus 로고
    • Modulation of chop-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
    • Tian, X. et al. Modulation of chop-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J. Biol. Chem. 286, 29408-29416 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 29408-29416
    • Tian, X.1
  • 35
    • 78449235291 scopus 로고    scopus 로고
    • Cisplatin-enhanced sensitivity of glioblastoma multiforme U251 cells to adenovirus-delivered TRAIL in vitro
    • Chen, J., Sun, X., Yang, W., Jiang, G. & Li, X. Cisplatin-enhanced sensitivity of glioblastoma multiforme U251 cells to adenovirus-delivered TRAIL in vitro. Tumour Biol. 31, 613-622 (2010).
    • (2010) Tumour Biol. , vol.31 , pp. 613-622
    • Chen, J.1    Sun, X.2    Yang, W.3    Jiang, G.4    Li, X.5
  • 36
    • 79955843451 scopus 로고    scopus 로고
    • Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions
    • Kahana, S. et al. Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions. Cell. Signal. 23, 1348-1357 (2011).
    • (2011) Cell. Signal. , vol.23 , pp. 1348-1357
    • Kahana, S.1
  • 37
    • 63249129117 scopus 로고    scopus 로고
    • Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2
    • Siegelin, M.D., Gaiser, T., Habel, A. & Siegelin, Y. Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2. Neurosci. Lett. 454, 223-228 (2009).
    • (2009) Neurosci. Lett. , vol.454 , pp. 223-228
    • Siegelin, M.D.1    Gaiser, T.2    Habel, A.3    Siegelin, Y.4
  • 38
    • 78651066526 scopus 로고    scopus 로고
    • Irradiation enhances the tumor tropism and therapeutic potential of tumor necrosis factor-related apoptosis-inducing ligand-secreting human umbilical cord blood-derived mesenchymal stem cells in glioma therapy
    • Kim, S.M. et al. Irradiation enhances the tumor tropism and therapeutic potential of tumor necrosis factor-related apoptosis-inducing ligand-secreting human umbilical cord blood-derived mesenchymal stem cells in glioma therapy. Stem Cells 28, 2217-2228 (2010).
    • (2010) Stem Cells , vol.28 , pp. 2217-2228
    • Kim, S.M.1
  • 39
    • 77953232760 scopus 로고    scopus 로고
    • Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors
    • van Eekelen, M. et al. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene 29, 3185-3195 (2010).
    • (2010) Oncogene , vol.29 , pp. 3185-3195
    • Van Eekelen, M.1
  • 40
    • 65949084271 scopus 로고    scopus 로고
    • A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR
    • Ren, B. et al. A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. Cancer Res. 69, 3856-3865 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 3856-3865
    • Ren, B.1
  • 41
    • 34249034598 scopus 로고    scopus 로고
    • Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL1
    • DOI 10.1593/neo.07223
    • Kock, N., Kasmieh, R., Weissleder, R. & Shah, K. Tumor therapy mediated by lentiviral expression of shBcl-2 and S-TRAIL. Neoplasia 9, 435-442 (2007). (Pubitemid 46799987)
    • (2007) Neoplasia , vol.9 , Issue.5 , pp. 435-442
    • Kock, N.1    Kasmieh, R.2    Weissledery, R.3    Shah, K.4
  • 42
    • 0344420263 scopus 로고    scopus 로고
    • Contrasting in Vivo and in Vitro Fates of Glioblastoma Cell Subpopulations with Amplified EGFR
    • DOI 10.1002/gcc.10300
    • Pandita, A., Aldape, K.D., Zadeh, G., Guha, A. & James, C.D. Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes Chromosom. Cancer 39, 29-36 (2004). (Pubitemid 37475250)
    • (2004) Genes Chromosomes and Cancer , vol.39 , Issue.1 , pp. 29-36
    • Pandita, A.1    Aldape, K.D.2    Zadeh, G.3    Guha, A.4    James, C.D.5
  • 43
    • 63849225752 scopus 로고    scopus 로고
    • Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
    • Wakimoto, H. et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 69, 3472-3481 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 3472-3481
    • Wakimoto, H.1
  • 44
    • 78651385352 scopus 로고    scopus 로고
    • A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models
    • Bagci-Onder, T., Wakimoto, H., Anderegg, M., Cameron, C. & Shah, K. A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models. Cancer Res. 71, 154-163 (2011).
    • (2011) Cancer Res. , vol.71 , pp. 154-163
    • Bagci-Onder, T.1    Wakimoto, H.2    Anderegg, M.3    Cameron, C.4    Shah, K.5
  • 45
    • 79958021185 scopus 로고    scopus 로고
    • The risk of putting something where it does not belong: Mesenchymal stem cells produce masses in the brain
    • Snyder, E.Y. The risk of putting something where it does not belong: Mesenchymal stem cells produce masses in the brain. Exp. Neurol. 230, 75-77 (2011).
    • (2011) Exp. Neurol. , vol.230 , pp. 75-77
    • Snyder, E.Y.1
  • 48
    • 79958059544 scopus 로고    scopus 로고
    • Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis
    • Grigoriadis, N. et al. Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis. Exp. Neurol. 230, 78-89 (2011).
    • (2011) Exp. Neurol. , vol.230 , pp. 78-89
    • Grigoriadis, N.1
  • 49
    • 80053536433 scopus 로고    scopus 로고
    • Human adipose tissue-derived mesenchymal stem cells: Characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas
    • published online doi:10.1016/j.ejca.2011.04.033 8 June
    • Choi, S.A. et al. Human adipose tissue-derived mesenchymal stem cells: characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas. Eur. J. Cancer published online, doi:10.1016/j.ejca.2011.04.033 (8 June 2011).
    • (2011) Eur. J. Cancer
    • Choi, S.A.1
  • 50
    • 79952710923 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: A new revolution for clinical neurology?
    • Mattis, V.B. & Svendsen, C.N. Induced pluripotent stem cells: a new revolution for clinical neurology? Lancet Neurol. 10, 383-394 (2011).
    • (2011) Lancet Neurol. , vol.10 , pp. 383-394
    • Mattis, V.B.1    Svendsen, C.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.