Chalcone-benzoxaborole hybrid molecules as potent antitrypanosomal agents

Journal of Medicinal Chemistry

Volumn 55, Issue 7, 2012, Pages 3553-3557

  Qiao, Zhitao ^a   Wang, Qi ^a   Zhang, Fenglong ^a   Wang, Zhongli ^a   Bowling, Tana ^b   Nare, Bakela ^b   Jacobs, Robert T ^b   Zhang, Jiong ^a   Ding, Dazhong ^a   Liu, Yangang ^a   Zhou, Huchen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SCYNEXIS Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIHYDRO 1 HYDROXY 6 (3 HYDROXY 3 PHENYLPROP 1 ENYL) 2,1 BENZOXABOROLE; ANTITRYPANOSOMAL AGENT; CHALCONE BENZOXABOROLE DERIVATIVE; CHALCONE DERIVATIVE; UNCLASSIFIED DRUG; [1 (1,3 DIHYDRO 1 HYDROXY 2,1 BENZOXABOROL 6 YL) 3 (4 AMINO 3 METHOXYPHENYL)]PROPENONE;

AFRICAN TRYPANOSOMIASIS; ANIMAL MODEL; ARTICLE; DRUG POTENCY; IC 50; MOUSE; NONHUMAN; PARASITEMIA; STRUCTURE ACTIVITY RELATION; SURVIVAL RATE; TRYPANOSOMA BRUCEI;

EID: 84859792163     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2012408     Document Type: Article

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