Regulation of the structurally dynamic N-terminal domain of progesterone receptor by protein-induced folding

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30285-30299

  Kumar, Raj ^a   Moure, Carmen M ^b   Khan, Shagufta H ^a   Callaway, Celetta ^b   Grimm, Sandra L ^b   Goswami, Devrishi ^c   Griffin, Patrick R ^c   Edwards, Dean P ^b  

^a Janet Weis Children s Hospital   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISORDER-ORDER TRANSITIONS; FOLDED CONFORMATION; MECHANISM OF ACTION; N-TERMINAL DOMAINS; PROGESTERONE RECEPTOR; STRUCTURAL REORGANIZATION; TARGET PROTEINS; TRANSCRIPTIONAL ACTIVATIONS;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

DEUTERIUM; HYDROGEN; PROGESTERONE RECEPTOR; TATA BINDING PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

HYDROGEN DEUTERIUM EXCHANGE MASS; INTRINSICALLY DISORDERED PROTEINS; MASS SPECTROMETRY (MS); N-TERMINAL TRANSCRIPTION ACTIVATION DOMAIN AF1; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN FOLDING; STEROID HORMONE RECEPTOR; TATA-BINDING PROTEIN;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; HUMANS; NUCLEAR RECEPTOR COACTIVATOR 1; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PROGESTERONE; SEQUENCE DELETION; TATA-BOX BINDING PROTEIN; TRANSCRIPTIONAL ACTIVATION;

EID: 84886930646     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.491787     Document Type: Article

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