Inhibitory effects and molecular mechanisms of garlic organosulfur compounds on the production of inflammatory mediators

Molecular Nutrition and Food Research

Volumn 57, Issue 11, 2013, Pages 2049-2060

  You, Sixiang ^a,b   Nakanishi, Eri ^b   Kuwata, Hiroko ^b   Chen, Jihua ^b,d   Nakasone, Yasushi ^c   He, Xi ^a   He, Jianhua ^a   Liu, Xiangxin ^a   Zhang, Shirui ^a   Zhang, Bin ^a   Hou, De Xing ^a,b  

^a HUNAN AGRICULTURAL UNIVERSITY   (China)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c Kenkoukazoku Inc   (Japan)

^d CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Garlic organosulfur compounds; Inflammatory mediators; MAPK; NF B; TGF activated kinase

Indexed keywords

ALLYL COMPOUND; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; DIALLYL TRISULFIDE; HEME OXYGENASE 1; HMOX1 PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MAP KINASE KINASE KINASE 7; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NFE2L2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE; NQO1 PROTEIN, MOUSE; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; PTGS2 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFIDE; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CHEMISTRY; DISEASE MODEL; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; EDEMA; GARLIC; GARLIC ORGANOSULFUR COMPOUNDS; INFLAMMATION; INFLAMMATORY MEDIATORS; MAPK; METABOLISM; MOUSE; NF-ΚB; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TGF-Β-ACTIVATED KINASE; TUMOR CELL LINE;

GARLIC ORGANOSULFUR COMPOUNDS; INFLAMMATORY MEDIATORS; MAPK; NF-ΚB; TGF-Β-ACTIVATED KINASE;

ALLYL COMPOUNDS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EDEMA; GARLIC; HEME OXYGENASE-1; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAP KINASE KINASE KINASES; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SULFIDES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84886776250     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200843     Document Type: Article

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