Spin echo measurements of the extravasation and tumor cell uptake of hyperpolarized [1-13C]lactate and [1-13C]pyruvate

Magnetic Resonance in Medicine

Volumn 70, Issue 5, 2013, Pages 1200-1209

  Kettunen, Mikko I ^a,b   Kennedy, Brett W C ^a,b   Hu, De En ^a,b   Brindle, Kevin M ^a,b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

diffusion; monocarboxylate transporter; perfusion; relaxation; transport

Indexed keywords

FINANCE; MAMMALS; MOLECULES; RATE CONSTANTS; RELAXATION TIME; SPIN POLARIZATION; TUMORS;

FREE INDUCTION DECAY SIGNALS (FID); INTRAVENOUS INJECTIONS; MONOCARBOXYLATE TRANSPORTER; PERFUSION; RELAXATION; SIMULTANEOUS ACQUISITION; SPIN-ECHO MEASUREMENTS; TRANSPORT;

DIFFUSION;

CARBON 13; CARRIER PROTEIN; CYCLOPROPANE DERIVATIVE; HP 001; HP 001 C 13; LACTIC ACID; LACTIC ACID C 13; PYRUVIC ACID; PYRUVIC ACID C 13; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DIFFUSION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EXTRAVASATION; DRUG TISSUE LEVEL; FEMALE; ISOTOPE LABELING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

DIFFUSION; MONOCARBOXYLATE TRANSPORTER; PERFUSION; RELAXATION; TRANSPORT;

ANIMALS; CARBON ISOTOPES; CELL LINE, TUMOR; FEMALE; LACTIC ACID; LYMPHOMA; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED C57BL; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPIN LABELS;

EID: 84886769763     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.24591     Document Type: Article

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