-
1
-
-
34247249906
-
Vascular disrupting agents in clinical development
-
Hinnen P, Eskens FALM. Vascular disrupting agents in clinical development. Br J Cancer 2007;96:1159-65.
-
(2007)
Br J Cancer
, vol.96
, pp. 1159-1165
-
-
Hinnen, P.1
Eskens, F.A.L.M.2
-
3
-
-
0032532391
-
Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4
-
Iyer S, Chaplin DJ, Rosenthal DS, Boulares AH, Li L, Smulson ME. Induction of apoptosis in proliferating human endothelial cells by the tumor-specific antiangiogenesis agent combretastatin A-4. Cancer Res 1998;58:4510-4.
-
(1998)
Cancer Res
, vol.58
, pp. 4510-4514
-
-
Iyer, S.1
Chaplin, D.J.2
Rosenthal, D.S.3
Boulares, A.H.4
Li, L.5
Smulson, M.E.6
-
4
-
-
0030951899
-
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
-
Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, Chaplin DJ. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 1997;57:1829-34.
-
(1997)
Cancer Res
, vol.57
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
Prise, V.E.3
Tozer, G.M.4
Pettit, G.R.5
Chaplin, D.J.6
-
5
-
-
0042386691
-
Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging
-
Galbraith SM, Maxwell RJ, Lodge MA, Tozer GM, Wilson J, Taylor NJ, et al. Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol 2003;21:2831-42.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2831-2842
-
-
Galbraith, S.M.1
Maxwell, R.J.2
Lodge, M.A.3
Tozer, G.M.4
Wilson, J.5
Taylor, N.J.6
-
6
-
-
33750299899
-
Phase II study of combretastatin A4 phosphate (CA4P) in patients with advanced anaplastic thyroid carcinoma (ATC)
-
Cooney MM, Savvides P, Agarwala S, Wang D, Flick S, Bergant S, et al. Phase II study of combretastatin A4 phosphate (CA4P) in patients with advanced anaplastic thyroid carcinoma (ATC). J Clin Oncol ASCO Meeting Abstr 2006;24:5580.
-
(2006)
J Clin Oncol ASCO Meeting Abstr
, vol.24
, pp. 5580
-
-
Cooney, M.M.1
Savvides, P.2
Agarwala, S.3
Wang, D.4
Flick, S.5
Bergant, S.6
-
7
-
-
76449086344
-
Combretastatin A-4 phosphate (CA4P) carboplatin an paclitaxel in patients with platinum-resistant ovarian cancer
-
Zweifel M, Jayson G, Reed N, Osborne R, Hassan B, Shreeves G, et al. Combretastatin A-4 phosphate (CA4P) carboplatin an paclitaxel in patients with platinum-resistant ovarian cancer. J Clin Oncol ASCO Meeting Abstr 2009;27:5502.
-
(2009)
J Clin Oncol ASCO Meeting Abstr
, vol.27
, pp. 5502
-
-
Zweifel, M.1
Jayson, G.2
Reed, N.3
Osborne, R.4
Hassan, B.5
Shreeves, G.6
-
8
-
-
68049108414
-
Vascular disrupting agents: A novel mechanism of action in the battle against non-small cell lung cancer
-
Gridelli C, Rossi A, Maione P, Rossi E, Castaldo V, Sacco PC, et al. Vascular disrupting agents: A novel mechanism of action in the battle against non-small cell lung cancer. Oncologist 2009;14:612-20.
-
(2009)
Oncologist
, vol.14
, pp. 612-620
-
-
Gridelli, C.1
Rossi, A.2
Maione, P.3
Rossi, E.4
Castaldo, V.5
Sacco, P.C.6
-
9
-
-
0042887593
-
Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
-
Anderson HL, Yap JT, Miller MP, Robbins A, Jones T, Price PM. Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate. J Clin Oncol 2003;21:2823-30.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2823-2830
-
-
Anderson, H.L.1
Yap, J.T.2
Miller, M.P.3
Robbins, A.4
Jones, T.5
Price, P.M.6
-
10
-
-
0035884395
-
The susceptibility of tumors to the antivascular dug combretastatin A4 phosphate correlates with vascular permeability
-
Beauregard DA, Hill SA, Chaplin DJ, Brindle KM. The susceptibility of tumors to the antivascular dug combretastatin A4 phosphate correlates with vascular permeability. Cancer Res 2001;61:6811-15.
-
(2001)
Cancer Res
, vol.61
, pp. 6811-6815
-
-
Beauregard, D.A.1
Hill, S.A.2
Chaplin, D.J.3
Brindle, K.M.4
-
11
-
-
47849090992
-
Quantitative imaging biomarkers in the clinical development of targeted therapeutics: Current and future perspectives
-
O'Connor JPB, Jackson A, Asselin M, Buckley DL, Parker GJM, Jackson GC. Quantitative imaging biomarkers in the clinical development of targeted therapeutics: Current and future perspectives. Lancet Oncol 2008;9:766-76.
-
(2008)
Lancet Oncol
, vol.9
, pp. 766-776
-
-
O'Connor, J.P.B.1
Jackson, A.2
Asselin, M.3
Buckley, D.L.4
Parker, G.J.M.5
Jackson, G.C.6
-
12
-
-
33745955010
-
Positron emission tomography as an imaging biomarker
-
Weber WA. Positron emission tomography as an imaging biomarker. J Clin Oncol 2006;24:3282-92.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3282-3292
-
-
Weber, W.A.1
-
13
-
-
33644689155
-
Diffusion-weighted magnetic resonance imaging allows noninvasive in vivo monitoring of the effects of combretastatin A-4 phosphate after repeated administration
-
Thoeny HC, De Keyzer F, Chen F, Vandecaveye V, Verbeken EK, Ahmed B, et al. Diffusion-weighted magnetic resonance imaging allows noninvasive in vivo monitoring of the effects of combretastatin A-4 phosphate after repeated administration. Neoplasia 2005;7:779-87.
-
(2005)
Neoplasia
, vol.7
, pp. 779-787
-
-
Thoeny, H.C.1
De Keyzer, F.2
Chen, F.3
Vandecaveye, V.4
Verbeken, E.K.5
Ahmed, B.6
-
14
-
-
27144541488
-
Effect of vascular targeting agent in rat tumor model: Dynamiccontrast enhanced versus diffusion-weighted MR imaging
-
Thoeny HC, Keyzer FD, Vandecaveye V, Chen F, Sun X, Bosmans H, et al. Effect of vascular targeting agent in rat tumor model: Dynamiccontrast enhanced versus diffusion-weighted MR imaging. Radiology 2005;237:492-9.
-
(2005)
Radiology
, vol.237
, pp. 492-499
-
-
Thoeny, H.C.1
Keyzer, F.D.2
Vandecaveye, V.3
Chen, F.4
Sun, X.5
Bosmans, H.6
-
15
-
-
34748865456
-
Diffusion magnetic resonance imaging: A biomarker for treatment response in oncology
-
DOI 10.1200/JCO.2007.11.9610
-
Hamstra DA, Rehemtulla A, Ross BD. Diffusion magnetic resonance imaging: A biomarker for treatment response in oncology. J Clin Oncol 2007;25:4104-9. (Pubitemid 47495868)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.26
, pp. 4104-4109
-
-
Hamstra, D.A.1
Rehemtulla, A.2
Ross, B.D.3
-
16
-
-
70350172813
-
Reproducibility and changes in the apparent diffusion coeffi- cients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial
-
Koh DM, Blackledge M, Collins DJ, Padhani AR, Wallace T, Wilton B, et al. Reproducibility and changes in the apparent diffusion coeffi- cients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial. Eur Radiol 2009;19:2728-38.
-
(2009)
Eur Radiol
, vol.19
, pp. 2728-2738
-
-
Koh, D.M.1
Blackledge, M.2
Collins, D.J.3
Padhani, A.R.4
Wallace, T.5
Wilton, B.6
-
17
-
-
0033065833
-
Positron emission tomography of murine liver metastases and the effects of treatment by combretastatin A-4
-
Zhao S, Moore JV, Waller ML, McGown AT, Hadfield JA, Pettit GR, et al. Positron emission tomography of murine liver metastases and the effects of treatment by combretastatin A-4. Eur J Nucl Med 1999;26:231-8.
-
(1999)
Eur J Nucl Med
, vol.26
, pp. 231-238
-
-
Zhao, S.1
Moore, J.V.2
Waller, M.L.3
McGown, A.T.4
Hadfield, J.A.5
Pettit, G.R.6
-
18
-
-
35148825036
-
Antitumor and antivascular effects of AVE8062 in ovarian carcinoma
-
Kim TJ, Ravoori M, Landen CN, Kamat AA, Han LY, Lu C, et al. Antitumor and antivascular effects of AVE8062 in ovarian carcinoma. Cancer Res 2007;67:9337-45.
-
(2007)
Cancer Res
, vol.67
, pp. 9337-9345
-
-
Kim, T.J.1
Ravoori, M.2
Landen, C.N.3
Kamat, A.A.4
Han, L.Y.5
Lu, C.6
-
20
-
-
0042763165
-
Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR
-
Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, et al. Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc Natl Acad Sci U S A 2003;100:10158-63.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10158-10163
-
-
Ardenkjaer-Larsen, J.H.1
Fridlund, B.2
Gram, A.3
Hansson, G.4
Hansson, L.5
Lerche, M.H.6
-
21
-
-
35948970970
-
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
-
Day SE, Kettunen MI, Gallagher FA, Hu DE, Lerche M, Wolber J, et al. Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 2007;13: 1382-7.
-
(2007)
Nat Med
, vol.13
, pp. 1382-1387
-
-
Day, S.E.1
Kettunen, M.I.2
Gallagher, F.A.3
Hu, D.E.4
Lerche, M.5
Wolber, J.6
-
22
-
-
66449129568
-
A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized 13C-labeled pyruvate utilization as methods for detecting tumor response to treatment
-
Witney TH, Kettunen MI, Day SE, Hu DE, Lerche M, Wolber J, et al. A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized 13C-labeled pyruvate utilization as methods for detecting tumor response to treatment. Neoplasia 2009;11:574-82.
-
(2009)
Neoplasia
, vol.11
, pp. 574-582
-
-
Witney, T.H.1
Kettunen, M.I.2
Day, S.E.3
Hu, D.E.4
Lerche, M.5
Wolber, J.6
-
23
-
-
73949133557
-
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]- fumarate is a marker of cell necrosis and treatment response in tumors
-
Gallagher FA, Kettunen MI, Hu D, Jensen PR, Zandt R, Karlsson M, et al. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]- fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci USA 2009;106(47):19801-6.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.47
, pp. 19801-19806
-
-
Gallagher, F.A.1
Kettunen, M.I.2
Hu, D.3
Jensen, P.R.4
Zandt, R.5
Karlsson, M.6
-
24
-
-
78650460580
-
Towards clinical studies of hyperpolarized carbon-13 metabolic imaging
-
Hawai'i
-
Vigneron D, Kurhanewicz J, Nelson S, Larson P, Hu S, von Morze C, et al. Towards clinical studies of hyperpolarized carbon-13 metabolic imaging. In: Proceedings of the 17th annual scientific meeting of the ISMRM; 2009; Hawai'i.
-
(2009)
Proceedings of the 17th annual scientific meeting of the ISMRM
-
-
Vigneron, D.1
Kurhanewicz, J.2
Nelson, S.3
Larson, P.4
Hu, S.5
Von Morze, C.6
-
25
-
-
45149112158
-
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate
-
Gallagher FA, Kettunen MI, Day SE, Hu DE, Ardenkjaer-Larsen JH, Zandt R, et al. Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate. Nature 2008;453:940-4.
-
(2008)
Nature
, vol.453
, pp. 940-944
-
-
Gallagher, F.A.1
Kettunen, M.I.2
Day, S.E.3
Hu, D.E.4
Ardenkjaer-Larsen, J.H.5
Zandt, R.6
-
26
-
-
0000191753
-
Lactate dehydrogenase
-
Bergmeyer HU, editor. Weinheim: Verlag Chemie GmbH;
-
Vassault A. Lactate dehydrogenase. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. Weinheim: Verlag Chemie GmbH; 1983. p. 118-26.
-
(1983)
Methods of Enzymatic Analysis
, pp. 118-126
-
-
Vassault, A.1
-
27
-
-
0001262581
-
Pyruvate, phosphoenolpyruvate and D-glycerate- 2-phosphate
-
Bergmeyer HU, editor. Verlag Chemie GmbH
-
Czok R, Lamprecht W. Pyruvate, phosphoenolpyruvate and D-glycerate- 2-phosphate. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. Verlag Chemie GmbH; 1974. p. 1446-51.
-
(1974)
Methods of Enzymatic Analysis.
, pp. 1446-1451
-
-
Czok, R.1
Lamprecht, W.2
-
28
-
-
0000831018
-
L-(+)-lactate: Determination with lactate dehydrogenase and NAD
-
Bergmeyer HU, editor. Verlag Chemie GmbH;
-
Gutmann I, Wahlefeld AW. L-(+)-lactate: Determination with lactate dehydrogenase and NAD. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. Verlag Chemie GmbH; 1974. p. 1464-8.
-
(1974)
Methods of Enzymatic Analysis.
, pp. 1464-1468
-
-
Gutmann, I.1
Wahlefeld, A.W.2
-
29
-
-
0003443852
-
L-malate and fumarate
-
Bergmeyer HU, editor. Verlag Chemie GmbH;
-
Goldberg ND, Passonneau JV. L-malate and fumarate. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis: Verlag Chemie GmbH; 1974. p. 1600-3.
-
(1974)
Methods of Enzymatic Analysis
, pp. 1600-1603
-
-
Goldberg, N.D.1
Passonneau, J.V.2
-
30
-
-
70649115375
-
Increase in tumour permeability following TGF-b type I receptorinhibitor treatment observed by dynamic contrast-enhanced MRI
-
Minowa T, Kawano K, Kuribayashi H, Shiraishi K, Sugino T, Hattori Y, et al. Increase in tumour permeability following TGF-b type I receptorinhibitor treatment observed by dynamic contrast-enhanced MRI. Br J Cancer 2009;101:1884-90.
-
(2009)
Br J Cancer
, vol.101
, pp. 1884-1890
-
-
Minowa, T.1
Kawano, K.2
Kuribayashi, H.3
Shiraishi, K.4
Sugino, T.5
Hattori, Y.6
-
31
-
-
33748376678
-
Preclinical evaluation of tumor microvascular response to a novel antiangiogenic/antitumor agent RO0281501 by dynamic contrastenhanced MRI at 1.5T
-
Muruganandham M, Lupu M, Dyke J, Matei C, Linn M, Packman K, et al. Preclinical evaluation of tumor microvascular response to a novel antiangiogenic/antitumor agent RO0281501 by dynamic contrastenhanced MRI at 1.5T. Mol Cancer Ther 2006;5:1950-7.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1950-1957
-
-
Muruganandham, M.1
Lupu, M.2
Dyke, J.3
Matei, C.4
Linn, M.5
Packman, K.6
-
33
-
-
78650472608
-
Haemorrhage
-
Reimer P, Parizel PM, Stichnoth FA, editors. 2nd ed.Berlin, Germany: Springer
-
Allkemper T. Haemorrhage. In: Reimer P, Parizel PM, Stichnoth FA, editors. Clinical MR Imaging: A Practical Approach. 2nd ed.Berlin, Germany:Springer; 2006. p. 64-76.
-
(2006)
Clinical MR Imaging: A Practical Approach
, pp. 64-76
-
-
Allkemper, T.1
-
34
-
-
51149108751
-
The effect of combretastatin A4 disodium phosphate and 5,6- dimethyxanthenone-4-acetic acid on water diffusion and blood perfusion in tumors
-
Chen G, Horsman MR, Pedersen M, Pang Q, Stodkilde-Jorgensen H. The effect of combretastatin A4 disodium phosphate and 5,6- dimethyxanthenone-4-acetic acid on water diffusion and blood perfusion in tumors. Acta Oncol 2008;47:1071-6.
-
(2008)
Acta Oncol
, vol.47
, pp. 1071-1076
-
-
Chen, G.1
Horsman, M.R.2
Pedersen, M.3
Pang, Q.4
Stodkilde-Jorgensen, H.5
-
35
-
-
0031770618
-
The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
-
Horsman MR, Ehrnrooth E, Ladekari M, Overgaard J. The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys 2000;42:895-8.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.42
, pp. 895-898
-
-
Horsman, M.R.1
Ehrnrooth, E.2
Ladekari, M.3
Overgaard, J.4
-
37
-
-
0035262598
-
Targeting tumour vasculature: The development of combretastatin A4
-
Griggs J, Metcalfe JC, Hesketh R. Targeting tumour vasculature: The development of combretastatin A4. Lancet Oncol 2001;2:82-7.
-
(2001)
Lancet Oncol
, vol.2
, pp. 82-87
-
-
Griggs, J.1
Metcalfe, J.C.2
Hesketh, R.3
-
38
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer 2009;45: 228-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
Schwartz, L.H.4
Sargent, D.5
Ford, R.6
-
39
-
-
77950623466
-
Magnetization transfer measurement of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma
-
Kettunen MI, Hu D, Witney TH, McLaughlin R, Gallagher FA, Bohndiek SE, et al. Magnetization transfer measurement of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma. Magn Reson Med 2010;63:872-80.
-
(2010)
Magn Reson Med
, vol.63
, pp. 872-880
-
-
Kettunen, M.I.1
Hu, D.2
Witney, T.H.3
McLaughlin, R.4
Gallagher, F.A.5
Bohndiek, S.E.6
-
40
-
-
33644629183
-
Coming up for air: HIF-1 and mitochondrial oxygen consumption
-
Simon MC. Coming up for air: HIF-1 and mitochondrial oxygen consumption. Cell Metab 2006;3:150-1.
-
(2006)
Cell Metab
, vol.3
, pp. 150-151
-
-
Simon, M.C.1
-
41
-
-
78650509373
-
Detecting response to treatment in human breast adenocarcinoma using a co-administration of hyperpolarized [1-13C]pyruvate and [14-13C2]fumarate
-
Stockholm
-
Witney TH, Kettunen MI, Hu D, Gallagher FA, Brindle KM. Detecting response to treatment in human breast adenocarcinoma using a co-administration of hyperpolarized [1-13C]pyruvate and [1,4-13C2]fumarate. In: 18th Scientific Meeting, International Society for Magnetic Resonance in Medicine; 2010; Stockholm.
-
(2010)
18th Scientific Meeting International Society for Magnetic Resonance in Medicine
-
-
Witney, T.H.1
Kettunen, M.I.2
Hu, D.3
Gallagher, F.A.4
Brindle, K.M.5
-
42
-
-
0034119889
-
Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging
-
Lyng H, Haraldseth O, Rofstad EK. Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging. Magn Reson Med 2000;43: 828-36.
-
(2000)
Magn Reson Med
, vol.43
, pp. 828-836
-
-
Lyng, H.1
Haraldseth, O.2
Rofstad, E.K.3
|