RIP2/RICK-Dependent Cytokine Production Upon Yersinia enterocolitica Infection in Macrophages with TLR4 Deficiency

Scandinavian Journal of Immunology

Volumn 78, Issue 5, 2013, Pages 401-407

  Jeong, Y J ^a   Kim, C H ^b   Kim, J C ^b   Oh, S M ^a   Lee, K B ^a   Park, J H ^a   Kim, D J ^a  

^a Konyang University   (South Korea)

^b Agency for Defence Development   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; GEFITINIB; INTERLEUKIN 10; INTERLEUKIN 6; PROTEIN; PROTEIN RICK; PROTEIN RIP2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; YERSINIA ENTEROCOLITICA; YERSINIA INFECTION;

ANIMALS; ENZYME INHIBITORS; IMIDAZOLES; INTERLEUKIN-10; INTERLEUKIN-6; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; PROTEIN KINASE INHIBITORS; PYRIDINES; PYRIMIDINES; QUINAZOLINES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; YERSINIA ENTEROCOLITICA; YERSINIA INFECTIONS;

EID: 84886745426     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12100     Document Type: Article

References (30)

1. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124:783-801.
2. Newton K, Dixit VM. Signaling in innate immunity and inflammation. Cold Spring Harb Perspect Biol 2012;4:a006049.
3. Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373-84.
4. Kanneganti T-D, Lamkanfi M, Núñez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007;27:549-59.
5. Davis BK, Wen H, Ting JP-Y. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol 2011;29:707-35.
6. Girardin SE, Boneca IG, Carneiro LAM et al. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 2003;300:1584-7.
7. Girardin SE, Boneca IG, Viala J et al. Nod2 is a general sensor of peptidoglycan through Muramyl Dipeptide (MDP) Detection. J Biol Chem 2003;278:8869-72.
8. Inohara N, Chamaillard M, McDonald C et al. NOD-LRR PROTEINS: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 2005;74:355-83.
9. Kim YG, Park JH, Shaw MH et al. The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to toll-like receptor ligands. Immunity 2008;28:246-57.
10. Park J-H, Kim Y-G, Núñez G. RICK promotes inflammation and lethality after Gram-Negative bacterial infection in mice stimulated with lipopolysaccharide. Infect Immun 2009;77:1569-78.
11. Chin AI, Dempsey PW, Bruhn K et al. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 2002;416:190-4.
12. Balamayooran T, Batra S, Balamayooran G et al. Receptor-interacting protein 2 controls pulmonary host defense to Escherichia coli infection via the regulation of interleukin-17A. Infect Immun 2011;79:4588-99.
13. Pandey AK, Yang Y, Jiang Z et al. NOD2, RIP2 and IRF5 play a critical role in the type i interferon response to Mycobacterium tuberculosis. PLoS Pathog 2009;5:e1000500.
14. Archer KA, Ader F, Kobayashi KS et al. Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila. Infect Immun 2010;78:2477-87.
15. Bottone EJ. Yersinia enterocolitica: overview and epidemiologic correlates. Microbes Infect 1999;1:323-33.
16. Galindo CL, Rosenzweig JA, Kirtley ML et al. Pathogenesis of Y. enterocolitica and Y. pseudotuberculosis in Human Yersiniosis. J Pathog 2011;2011:182051.
17. Sing A, Tvardovskaia N, Rost D et al. Contribution of Toll-like receptors 2 and 4 in an oral Yersinia enterocolitica mouse infection model. Int J Med Microbiol 2003;293:341-8.
18. Sing A, Reithmeier-Rost D, Granfors K, Hill J, Roggenkamp A, Heesemann J. A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence. Proc Natl Acad Sci USA 2005;102:16049-54.
19. Jeong YJ, Kim CH, Song EJ et al. Nucleotide-binding oligomerization domain 2 (Nod2) is dispensable for the innate immune responses of macrophages against Yersinia enterocolitica. J Microbiol 2012;50:489-95.
20. Celada A, Gray PW, Rinderknecht E et al. Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity. J Exp Med 1984;160:55.
21. Dobrovolskaia MA, Vogel SN. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect 2002;4:903-14.
22. Argast GM, Fausto N, Campbell JS. Inhibition of RIP2/RIck/CARDIAK activity by pyridinyl imidazole inhibitors of p38 MAPK. Mol Cell Biochem 2005;268:129-40.
23. Tigno-Aranjuez JT, Asara JM, Abbott DW. Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses. Genes Dev 2010;24:2666-77.
24. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011;34:637-50.
25. Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010;140:805-20.
26. Smythies LE, Sellers M, Clements RH et al. Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest 2005;115:66-75.
27. Franchi L, Kamada N, Nakamura Y et al. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol 2012;13:449-56.
28. Kobayashi KS, Chamaillard M, Ogura Y et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005;307:731-4.
29. Marijke Keestra A, Winter MG, Klein-Douwel D et al. A salmonella virulence factor activates the NOD1/NOD2 signaling pathway. MBio 2011;2:e00266-11.
30. Viala J, Chaput C, Boneca IG et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 2004;5:1166-74.