Distribution Studies of Drugs and Metabolites in Tissue by Mass Spectrometric Imaging

Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Volumn , Issue , 2011, Pages 449-482

  Reich, Richard F ^a   Magparangalan, Daniel P ^a   Garrett, Timothy J ^a   Yost, Richard A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Distribution studies of drugs and metabolites in tissue by MS imaging pharmacological activity and ADMET (adsorption, distribution, metabolism, elimination, and toxicity) properties of drug candidates in vivo; Mass spectrometric imaging (MSI), and higher molecular specificity applications of MSI in detection of tissue drug metabolites; MSI methodology, using mass spectrometer as imaging instruments sophisticated data acquisition system, for data acquired in analysis

Indexed keywords

EID: 84886550932     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470929278.ch14     Document Type: Chapter

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