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Volumn 16, Issue 4, 2002, Pages 378-387

It's not just about anatomy: In vivo bioluminescence imaging as an eyepiece into biology

Author keywords

Cancer; Gene expression; Luciferase; Molecular imaging; MRI

Indexed keywords

DNA; ETOPOSIDE; FLUCYTOSINE; FLUOROURACIL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GREEN FLUORESCENT PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; INTEIN; INTERLEUKIN 12; LUCIFERASE; MYELIN BASIC PROTEIN; MYOD PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTATE SPECIFIC ANTIGEN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 6;

EID: 0036793192     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.10178     Document Type: Review
Times cited : (249)

References (92)
  • 1
    • 0034006553 scopus 로고    scopus 로고
    • Imaging in cancer: A National Cancer Institute "extraordinary opportunity"
    • Hoffman JM. Imaging in cancer: a National Cancer Institute "extraordinary opportunity". Neoplasia 2000;2:5-8.
    • (2000) Neoplasia , vol.2 , pp. 5-8
    • Hoffman, J.M.1
  • 2
    • 0002179495 scopus 로고    scopus 로고
    • Molecular imaging of gene expression and efficacy following adenoviral-mediated brain tumor gene therapy
    • Rehemtulla A, Hall DE, Stegmanet LD, et al. Molecular imaging of gene expression and efficacy following adenoviral-mediated brain tumor gene therapy. Molec Imaging 2002;1:43-55.
    • (2002) Molec Imaging , vol.1 , pp. 43-55
    • Rehemtulla, A.1    Hall, D.E.2    Stegmanet, L.D.3
  • 3
    • 0034954524 scopus 로고    scopus 로고
    • In vivo molecular target assessment of matrix metalloproteinase inhibition
    • Bremer C, Tung CH, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001;7:743-748.
    • (2001) Nat Med , vol.7 , pp. 743-748
    • Bremer, C.1    Tung, C.H.2    Weissleder, R.3
  • 4
    • 0034652156 scopus 로고    scopus 로고
    • Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
    • Chinnaiyan AM, Prasad U, Shankar S, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci U S A 2000;97:1754-1759.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1754-1759
    • Chinnaiyan, A.M.1    Prasad, U.2    Shankar, S.3
  • 5
    • 0034486139 scopus 로고    scopus 로고
    • Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging
    • Rehemtulla A, Stegman LD, Cardozo SJ, et al. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia 2000;2:491-495.
    • (2000) Neoplasia , vol.2 , pp. 491-495
    • Rehemtulla, A.1    Stegman, L.D.2    Cardozo, S.J.3
  • 6
    • 0034047595 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Cancer therapeutics
    • Evelhoch JL, Gillies RJ, Karczmar GS, et al. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia 2000;2:152-165.
    • (2000) Neoplasia , vol.2 , pp. 152-165
    • Evelhoch, J.L.1    Gillies, R.J.2    Karczmar, G.S.3
  • 7
    • 0034087595 scopus 로고    scopus 로고
    • Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer
    • Kurhanewicz J, Vigneron DB, Nelson SJ. Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer. Neoplasia 2000;2:166-189.
    • (2000) Neoplasia , vol.2 , pp. 166-189
    • Kurhanewicz, J.1    Vigneron, D.B.2    Nelson, S.J.3
  • 8
    • 0033813154 scopus 로고    scopus 로고
    • HGF/SF activates glycolysis and oxidative phosphorylation in DA3 murine mammary cancer cells
    • Kaplan O, Firon M, Vivi A, Navon G, Tsarfaty I, et al. HGF/SF activates glycolysis and oxidative phosphorylation in DA3 murine mammary cancer cells. Neoplasia 2000;2:365-377.
    • (2000) Neoplasia , vol.2 , pp. 365-377
    • Kaplan, O.1    Firon, M.2    Vivi, A.3    Navon, G.4    Tsarfaty, I.5
  • 10
    • 0002808589 scopus 로고    scopus 로고
    • Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets
    • Bogdanov A, Matuszewski L, Bremer C, Petrovsky A, Weissleder R. Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets. Molec Imaging 2002;1:16-23.
    • (2002) Molec Imaging , vol.1 , pp. 16-23
    • Bogdanov, A.1    Matuszewski, L.2    Bremer, C.3    Petrovsky, A.4    Weissleder, R.5
  • 11
    • 0033652083 scopus 로고    scopus 로고
    • Improvement of MRI probes to allow efficient detection of gene expression
    • Hogemann D, Josephson L, Weissleder R, Basilion JP. Improvement of MRI probes to allow efficient detection of gene expression. Bioconjug Chem 2000;11:941-946.
    • (2000) Bioconjug Chem , vol.11 , pp. 941-946
    • Hogemann, D.1    Josephson, L.2    Weissleder, R.3    Basilion, J.P.4
  • 12
    • 0034006104 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Tumor biology and physiology
    • Gillies RJ, Bhujwalla ZM, Evelhoch J. et al. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2000;2:139-151.
    • (2000) Neoplasia , vol.2 , pp. 139-151
    • Gillies, R.J.1    Bhujwalla, Z.M.2    Evelhoch, J.3
  • 13
    • 0035052324 scopus 로고    scopus 로고
    • Vascular differences detected by MRI for metastatic versus non-metastatic breast and prostate cancer xenografts
    • Bhujwalla ZM, Artemov D, Natarajan K, Ackerstaff E, Solalyappan M. Vascular differences detected by MRI for metastatic versus non-metastatic breast and prostate cancer xenografts. Neoplasia 2001;3:143-153.
    • (2001) Neoplasia , vol.3 , pp. 143-153
    • Bhujwalla, Z.M.1    Artemov, D.2    Natarajan, K.3    Ackerstaff, E.4    Solalyappan, M.5
  • 14
    • 0034038709 scopus 로고    scopus 로고
    • Imaging prostate cancer invasion with multi-nuclear magnetic resonance methods: The Metabolic Boyden Chamber
    • Pilatus U, Ackerstaff E, Artemov D, Mori N, Gillies RJ, Bhujwalla ZM. Imaging prostate cancer invasion with multi-nuclear magnetic resonance methods: the Metabolic Boyden Chamber. Neoplasia 2000;2:273-279.
    • (2000) Neoplasia , vol.2 , pp. 273-279
    • Pilatus, U.1    Ackerstaff, E.2    Artemov, D.3    Mori, N.4    Gillies, R.J.5    Bhujwalla, Z.M.6
  • 16
    • 0033578358 scopus 로고    scopus 로고
    • Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy
    • Stegman LD, Rehemtulla A, Beattie B, et al. Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy. Proc Natl Acad Sci U S A 1999;96:9821-9826.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9821-9826
    • Stegman, L.D.1    Rehemtulla, A.2    Beattie, B.3
  • 17
    • 0035216077 scopus 로고    scopus 로고
    • Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo
    • Ponomarev V, Doubrovin M, Lyddane C, et al. Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo. Neoplasia 2001;3:480-488.
    • (2001) Neoplasia , vol.3 , pp. 480-488
    • Ponomarev, V.1    Doubrovin, M.2    Lyddane, C.3
  • 18
    • 0034048929 scopus 로고    scopus 로고
    • Imaging transgene expression with radionuclide imaging technologies
    • Gambhir SS, Herschman HR, Cherry SR, et al. Imaging transgene expression with radionuclide imaging technologies. Neoplasia 2000;2:118-138.
    • (2000) Neoplasia , vol.2 , pp. 118-138
    • Gambhir, S.S.1    Herschman, H.R.2    Cherry, S.R.3
  • 19
    • 0033205584 scopus 로고    scopus 로고
    • A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase
    • Tjuvajev JG, Joshi A, Callegari J, et al. A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia 1999;1:315-320.
    • (1999) Neoplasia , vol.1 , pp. 315-320
    • Tjuvajev, J.G.1    Joshi, A.2    Callegari, J.3
  • 20
    • 13044260220 scopus 로고    scopus 로고
    • Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography
    • Gambhir SS, Barrio JR, Wu L, et al. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc Natl Acad Sci U S A 1999;96:2333-2338.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2333-2338
    • Gambhir, S.S.1    Barrio, J.R.2    Wu, L.3
  • 21
    • 0034087594 scopus 로고    scopus 로고
    • Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors
    • Mankoff DA, Dehdashtiand F, Shields AF. Characterizing tumors using metabolic imaging: PET imaging of cellular proliferation and steroid receptors. Neoplasia 2000;2:71-88.
    • (2000) Neoplasia , vol.2 , pp. 71-88
    • Mankoff, D.A.1    Dehdashtiand, F.2    Shields, A.F.3
  • 22
    • 0002843419 scopus 로고    scopus 로고
    • Characterization of a novel 99mTc-carbonyl complex as a functional probe of MDR1 P-glycoprotein transport activity
    • Dyszlewski M, Blake HM, Dahlheimer JL, Pica CM, Piwnica-Worms D. Characterization of a novel 99mTc-carbonyl complex as a functional probe of MDR1 P-glycoprotein transport activity. Molec Imaging 2002;1:24-36.
    • (2002) Molec Imaging , vol.1 , pp. 24-36
    • Dyszlewski, M.1    Blake, H.M.2    Dahlheimer, J.L.3    Pica, C.M.4    Piwnica-Worms, D.5
  • 23
    • 0002016402 scopus 로고    scopus 로고
    • Imaging expression of cytosine deaminase - Herpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET
    • Hackman T, Doubrovin M, Balatoni J, et al. Imaging expression of cytosine deaminase - herpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET. Molec Imaging 2002;1:36-42.
    • (2002) Molec Imaging , vol.1 , pp. 36-42
    • Hackman, T.1    Doubrovin, M.2    Balatoni, J.3
  • 24
    • 0002704698 scopus 로고    scopus 로고
    • Radioimmunoscintigraphy of tumors autocrine for human Met and hepatocyte growth factor/scatter factor
    • Hay RV, Cao B, Skinner RS, et al. Radioimmunoscintigraphy of tumors autocrine for human Met and hepatocyte growth factor/ scatter factor. Molec Imaging 2002;1:56-62.
    • (2002) Molec Imaging , vol.1 , pp. 56-62
    • Hay, R.V.1    Cao, B.2    Skinner, R.S.3
  • 25
    • 0034885978 scopus 로고    scopus 로고
    • Using positron emission tomography with [(18)F]FDG to predict tumor behavior in experimental colorectal cancer
    • Burt BM, Humm JL, Kooby DA, et al. Using positron emission tomography with [(18)F]FDG to predict tumor behavior in experimental colorectal cancer. Neoplasia 2001;3:189-195.
    • (2001) Neoplasia , vol.3 , pp. 189-195
    • Burt, B.M.1    Humm, J.L.2    Kooby, D.A.3
  • 26
    • 0033287181 scopus 로고    scopus 로고
    • Changes in vascularization of human breast cancer xenografts responding to antiestrogen therapy
    • Kristensen CA, Hamberg LM, Hunter GJ, et al. Changes in vascularization of human breast cancer xenografts responding to antiestrogen therapy. Neoplasia 1999;1:518-525.
    • (1999) Neoplasia , vol.1 , pp. 518-525
    • Kristensen, C.A.1    Hamberg, L.M.2    Hunter, G.J.3
  • 27
    • 0034088968 scopus 로고    scopus 로고
    • High resolution X-ray computed tomography: An emerging tool for small animal cancer research
    • Paulus MJ, Gleason SS, Kennel SJ, Hunsicker PR, Johnson DK. High resolution X-ray computed tomography: an emerging tool for small animal cancer research. Neoplasia 2000;2:62-70.
    • (2000) Neoplasia , vol.2 , pp. 62-70
    • Paulus, M.J.1    Gleason, S.S.2    Kennel, S.J.3    Hunsicker, P.R.4    Johnson, D.K.5
  • 28
    • 0034486945 scopus 로고    scopus 로고
    • Imaging proteolysis by living human breast cancer cells
    • Sameni M, Moin K, Sloane BF. Imaging proteolysis by living human breast cancer cells. Neoplasia 2000;2:496-504.
    • (2000) Neoplasia , vol.2 , pp. 496-504
    • Sameni, M.1    Moin, K.2    Sloane, B.F.3
  • 29
    • 0033139768 scopus 로고    scopus 로고
    • Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: Implications for noninvasive imaging of transgene expression
    • Jacobs A, Dubrovin M, Hewett J, et al. Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia 1999;1:154-161.
    • (1999) Neoplasia , vol.1 , pp. 154-161
    • Jacobs, A.1    Dubrovin, M.2    Hewett, J.3
  • 30
    • 0343938561 scopus 로고    scopus 로고
    • Optical coherence tomography: An emerging technology for biomedical imaging and optical biopsy
    • Fujimoto JG, Pitris C, Boppart SA, Brezinski ME. Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. Neoplasia 2000;2:9-25.
    • (2000) Neoplasia , vol.2 , pp. 9-25
    • Fujimoto, J.G.1    Pitris, C.2    Boppart, S.A.3    Brezinski, M.E.4
  • 31
    • 0033624632 scopus 로고    scopus 로고
    • Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy
    • Tromberg BJ, Shah N, Lanning R, et al. Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy. Neoplasia 2000;2:26-40.
    • (2000) Neoplasia , vol.2 , pp. 26-40
    • Tromberg, B.J.1    Shah, N.2    Lanning, R.3
  • 32
    • 0034005797 scopus 로고    scopus 로고
    • Intravital fluorescence videomicroscopy to study tumor angiogenesis and microcirculation
    • Vajkoczy P, Ullrich A, Menger MD. Intravital fluorescence videomicroscopy to study tumor angiogenesis and microcirculation. Neoplasia 2000;2:53-61.
    • (2000) Neoplasia , vol.2 , pp. 53-61
    • Vajkoczy, P.1    Ullrich, A.2    Menger, M.D.3
  • 33
    • 0034050985 scopus 로고    scopus 로고
    • Fluorescence spectroscopy of neoplastic and non-neoplastic tissues
    • Ramanujam N. Fluorescence spectroscopy of neoplastic and non-neoplastic tissues. Neoplasia 2000;2:89-117.
    • (2000) Neoplasia , vol.2 , pp. 89-117
    • Ramanujam, N.1
  • 34
    • 0035093491 scopus 로고    scopus 로고
    • Co-regulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro
    • Pedersen MW, Holm S, Lund EL, Hojgaard L, Kristjansen PE. Co-regulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro. Neoplasia 2001;3:80-87.
    • (2001) Neoplasia , vol.3 , pp. 80-87
    • Pedersen, M.W.1    Holm, S.2    Lund, E.L.3    Hojgaard, L.4    Kristjansen, P.E.5
  • 35
    • 0034878286 scopus 로고    scopus 로고
    • Quantitative estimates of vascularity in solid tumors by non-invasive near-infrared spectroscopy
    • Kragh M, Quistorff B, Lund EL, Kristjansen PE. Quantitative estimates of vascularity in solid tumors by non-invasive near-infrared spectroscopy. Neoplasia 2001;3;324-330.
    • (2001) Neoplasia , vol.3 , pp. 324-330
    • Kragh, M.1    Quistorff, B.2    Lund, E.L.3    Kristjansen, P.E.4
  • 36
    • 0035215945 scopus 로고    scopus 로고
    • Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation
    • Vordermark D, Shibata T, Brown JM. Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation. Neoplasia 2001;3:527-534.
    • (2001) Neoplasia , vol.3 , pp. 527-534
    • Vordermark, D.1    Shibata, T.2    Brown, J.M.3
  • 38
    • 0034005650 scopus 로고    scopus 로고
    • Use of reporter genes for optical measurements of neoplastic disease in vivo
    • Contag CH, Jenkins D, Contag PR, Negrin RS. Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia 2000;2:41-52.
    • (2000) Neoplasia , vol.2 , pp. 41-52
    • Contag, C.H.1    Jenkins, D.2    Contag, P.R.3    Negrin, R.S.4
  • 39
    • 0003138605 scopus 로고    scopus 로고
    • Conventional and high-speed intravital multiphoton laser scanning microscopy of microvasculature, lymphatics, and leukocyte-endothelial interactions
    • Padera TP, Stoll BR, So PTC, Jain RK. Conventional and high-speed intravital multiphoton laser scanning microscopy of microvasculature, lymphatics, and leukocyte-endothelial interactions. Molec Imaging 2002;1:9-15.
    • (2002) Molec Imaging , vol.1 , pp. 9-15
    • Padera, T.P.1    Stoll, B.R.2    So, P.T.C.3    Jain, R.K.4
  • 40
    • 0034523747 scopus 로고    scopus 로고
    • Developments toward diagnostic breast cancer imaging using near-infrared optical measurements and fluorescent contrast agents
    • Hawrysz DJ, Sevick-Muraca EM. Developments toward diagnostic breast cancer imaging using near-infrared optical measurements and fluorescent contrast agents. Neoplasia 2000;2:388-417.
    • (2000) Neoplasia , vol.2 , pp. 388-417
    • Hawrysz, D.J.1    Sevick-Muraca, E.M.2
  • 41
    • 12644305918 scopus 로고    scopus 로고
    • Governing step of metastasis visualized in vitro
    • Chishima T, Yang M, Miyagi Y, et al. Governing step of metastasis visualized in vitro, Proc Natl Acad Sci U S A 1997;94:11573-11576.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11573-11576
    • Chishima, T.1    Yang, M.2    Miyagi, Y.3
  • 42
    • 0032409738 scopus 로고    scopus 로고
    • Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis
    • Hoffman RM. Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis. Cancer Metastasis Rev 1998;17:271-277.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 271-277
    • Hoffman, R.M.1
  • 43
    • 0032693955 scopus 로고    scopus 로고
    • Visualizing the kinetics of tumor-cell clearance in living animals
    • Sweeney TJ, Mailander V. Tucker AA, et al. Visualizing the kinetics of tumor-cell clearance in living animals. Proc Natl Acad Sci U S A 1999;96:12044-12049.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12044-12049
    • Sweeney, T.J.1    Mailander, V.2    Tucker, A.A.3
  • 44
    • 12944327946 scopus 로고    scopus 로고
    • Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases
    • Yang M, Baranov E, Jiang P, et al. Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A 2000;97:1206-1211.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1206-1211
    • Yang, M.1    Baranov, E.2    Jiang, P.3
  • 45
    • 0033870411 scopus 로고    scopus 로고
    • Haemoglobin interferes with the ex vivo luciferase luminescence assay: Consequence for detection of luciferase reporter gene expression in vivo
    • Colin M, Moritz S, Schneider H, Capeau J, Coutelle C, Brahimi-Horn MC. Haemoglobin interferes with the ex vivo luciferase luminescence assay: consequence for detection of luciferase reporter gene expression in vivo. Gene Ther 2000;7:1333-1336.
    • (2000) Gene Ther , vol.7 , pp. 1333-1336
    • Colin, M.1    Moritz, S.2    Schneider, H.3    Capeau, J.4    Coutelle, C.5    Brahimi-Horn, M.C.6
  • 46
    • 0037083555 scopus 로고    scopus 로고
    • A simple method to overcome the interference of hemoglobin in the detection of reporter genes in vivo
    • Reynier P, Lesage D, Cao A, Briane D, Coudert R, Taillandier E. A simple method to overcome the interference of hemoglobin in the detection of reporter genes in vivo. Anal Biochem 2002;301:217-224.
    • (2002) Anal Biochem , vol.301 , pp. 217-224
    • Reynier, P.1    Lesage, D.2    Cao, A.3    Briane, D.4    Coudert, R.5    Taillandier, E.6
  • 47
    • 0034327889 scopus 로고    scopus 로고
    • Luminometric quantitation of photinus pyralis firefly luciferase and Escherichia coli beta-galactosidase in blood-contaminated organ lysates
    • Smith AD, Trempe JP. Luminometric quantitation of photinus pyralis firefly luciferase and Escherichia coli beta-galactosidase in blood-contaminated organ lysates. Anal Biochem 2000;286:164-172.
    • (2000) Anal Biochem , vol.286 , pp. 164-172
    • Smith, A.D.1    Trempe, J.P.2
  • 50
    • 0029939559 scopus 로고    scopus 로고
    • Chemistries and colors of bioluminescent reactions: A review
    • Hastings JW. Chemistries and colors of bioluminescent reactions: a review. Gene 1996;173:5-11.
    • (1996) Gene , vol.173 , pp. 5-11
    • Hastings, J.W.1
  • 52
    • 0035470983 scopus 로고    scopus 로고
    • In vivo imaging of light-emitting probes
    • Rice BW, Cable MD, Nelson MB. In vivo imaging of light-emitting probes. J Biomed Opt 2001;6:432-440.
    • (2001) J Biomed Opt , vol.6 , pp. 432-440
    • Rice, B.W.1    Cable, M.D.2    Nelson, M.B.3
  • 53
    • 0035210676 scopus 로고    scopus 로고
    • Detection of GDNF secretion in glial cell culture and from transformed cell implants in the brains of live animals
    • Liu H, Iacono RP, Szalay AA. Detection of GDNF secretion in glial cell culture and from transformed cell implants in the brains of live animals. Mol Genet Genomics 2001;266:614-623.
    • (2001) Mol Genet Genomics , vol.266 , pp. 614-623
    • Liu, H.1    Iacono, R.P.2    Szalay, A.A.3
  • 54
    • 0037086089 scopus 로고    scopus 로고
    • Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice
    • Vooijs M, Jonkers J, Lyons S, Berns A. Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice. Cancer Res 2002;62:1862-1867.
    • (2002) Cancer Res , vol.62 , pp. 1862-1867
    • Vooijs, M.1    Jonkers, J.2    Lyons, S.3    Berns, A.4
  • 55
    • 0036118348 scopus 로고    scopus 로고
    • Optical imaging of cancer metastasis to bone marrow: A mouse model of minimal residual disease
    • Wetterwald A. van der Pluijm G, Que I. Optical imaging of cancer metastasis to bone marrow: a mouse model of minimal residual disease. Am J Pathol 2002;160:1143-1153.
    • (2002) Am J Pathol , vol.160 , pp. 1143-1153
    • Wetterwald, A.1    Van der Pluijm, G.2    Que, I.3
  • 57
    • 0036363666 scopus 로고    scopus 로고
    • Imaging of light emission from the expression of luciferases in living cells and organisms: A review
    • Greer III LF, Szalay AA. Imaging of light emission from the expression of luciferases in living cells and organisms: a review. Luminescence 2002;17:43-74.
    • (2002) Luminescence , vol.17 , pp. 43-74
    • Greer L.F. III1    Szalay, A.A.2
  • 58
    • 0034849299 scopus 로고    scopus 로고
    • Imaging transgene expression in live animals
    • Honigman A, Zeira E, Ohana P. et al. Imaging transgene expression in live animals. Mol Ther 2001;4:239-249.
    • (2001) Mol Ther , vol.4 , pp. 239-249
    • Honigman, A.1    Zeira, E.2    Ohana, P.3
  • 59
    • 0032216620 scopus 로고    scopus 로고
    • An evaluation of exact and approximate 3-D reconstruction algorithms for a high-resolution, small-animal PET scanner
    • Farquhar TH, Chatziioannouand HA, Cherry SR. An evaluation of exact and approximate 3-D reconstruction algorithms for a high-resolution, small-animal PET scanner. IEEE Trans Med Imaging 1998;17:1073-1080.
    • (1998) IEEE Trans Med Imaging , vol.17 , pp. 1073-1080
    • Farquhar, T.H.1    Chatziioannouand, H.A.2    Cherry, S.R.3
  • 60
    • 0031742514 scopus 로고    scopus 로고
    • Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir
    • Gambhir SS, Barrio JR, Wu L, et al. Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J Nucl Med 1998;39:2003-2011.
    • (1998) J Nucl Med , vol.39 , pp. 2003-2011
    • Gambhir, S.S.1    Barrio, J.R.2    Wu, L.3
  • 61
    • 17144471900 scopus 로고    scopus 로고
    • Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
    • Tjuvajev JG, Avril N, Oku T, et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 1998;58:4333-4341.
    • (1998) Cancer Res , vol.58 , pp. 4333-4341
    • Tjuvajev, J.G.1    Avril, N.2    Oku, T.3
  • 62
    • 0034760638 scopus 로고    scopus 로고
    • Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice
    • Wu JC, Sundaresan G, Iyer M, Gambhir SS, et al. Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Mol Ther 2001;4:297-306.
    • (2001) Mol Ther , vol.4 , pp. 297-306
    • Wu, J.C.1    Sundaresan, G.2    Iyer, M.3    Gambhir, S.S.4
  • 63
    • 0028118111 scopus 로고
    • Tumor spectrum analysis in p53-mutant mice
    • Jacks T, Remington L, Williams BO, et al. Tumor spectrum analysis in p53-mutant mice. Curr Biol 1994;4:1-17.
    • (1994) Curr Biol , vol.4 , pp. 1-17
    • Jacks, T.1    Remington, L.2    Williams, B.O.3
  • 64
    • 0032954092 scopus 로고    scopus 로고
    • Insights into cancer from transgenic mouse models
    • Macleod KF, Jacks T. Insights into cancer from transgenic mouse models. J Pathol 1999;187:43-60.
    • (1999) J Pathol , vol.187 , pp. 43-60
    • Macleod, K.F.1    Jacks, T.2
  • 65
    • 0037169361 scopus 로고    scopus 로고
    • Cancer modeling in the modem era: Progress and challenges
    • Van Dyke T, Jacks T. Cancer modeling in the modem era: progress and challenges. Cell 2002;108:135-144.
    • (2002) Cell , vol.108 , pp. 135-144
    • Van Dyke, T.1    Jacks, T.2
  • 67
    • 0035881597 scopus 로고    scopus 로고
    • Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit
    • Costa GL, Sandora MR, Nakajima A, et al. Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. J Immunol 2001;167:2379-2387.
    • (2001) J Immunol , vol.167 , pp. 2379-2387
    • Costa, G.L.1    Sandora, M.R.2    Nakajima, A.3
  • 68
    • 0035003202 scopus 로고    scopus 로고
    • Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis
    • Nakajima A, Seroogy CM, Sandora MR, et al. Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. J Clin Invest 2001;107:1293-1301.
    • (2001) J Clin Invest , vol.107 , pp. 1293-1301
    • Nakajima, A.1    Seroogy, C.M.2    Sandora, M.R.3
  • 69
    • 0028235084 scopus 로고
    • Real time measurement of gene expression in living endocrine cells
    • Frawley LS, Faught WJ, Nicholson J, Moomaw B. Real time measurement of gene expression in living endocrine cells. Endocrinology 1994;135:468-471.
    • (1994) Endocrinology , vol.135 , pp. 468-471
    • Frawley, L.S.1    Faught, W.J.2    Nicholson, J.3    Moomaw, B.4
  • 72
    • 0028918751 scopus 로고
    • Real time imaging of transcriptional activity in live mouse preimplantation embryos using a secreted luciferase
    • Thompson EM, Adenot P, Tsuji FI, Renard JP. Real time imaging of transcriptional activity in live mouse preimplantation embryos using a secreted luciferase. Proc Natl Acad Sci U S A 1995;92:1317-1321.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1317-1321
    • Thompson, E.M.1    Adenot, P.2    Tsuji, F.I.3    Renard, J.P.4
  • 73
    • 0028900378 scopus 로고
    • Real-time analysis of the transcriptional regulation of HIV and hCMV promoters in single mammalian cells
    • White MR, Masuko M, Amet L, et al. Real-time analysis of the transcriptional regulation of HIV and hCMV promoters in single mammalian cells. J Cell Sci 1995;108:441-455.
    • (1995) J Cell Sci , vol.108 , pp. 441-455
    • White, M.R.1    Masuko, M.2    Amet, L.3
  • 74
    • 0029813659 scopus 로고    scopus 로고
    • Real-time imaging of transcription in living cells and tissues
    • White MR, Wood CD, Millar CD. Real-time imaging of transcription in living cells and tissues. Biochem Soc Trans 1996;24;411S.
    • (1996) Biochem Soc Trans , vol.24
    • White, M.R.1    Wood, C.D.2    Millar, C.D.3
  • 75
    • 0026918135 scopus 로고
    • A novel circadian phenotype based on firefly luciferase expression in transgenic plants
    • Millar AJ, Short SR, Chua NH, Kay SA. A novel circadian phenotype based on firefly luciferase expression in transgenic plants. Plant Cell 1992;4:1075-1087.
    • (1992) Plant Cell , vol.4 , pp. 1075-1087
    • Millar, A.J.1    Short, S.R.2    Chua, N.H.3    Kay, S.A.4
  • 76
    • 0028902249 scopus 로고
    • Circadian clock mutants in Arabidopsis identified by luciferase imaging
    • Millar AJ, Carre IA, Strayer CA, Chua NH, Kay SA. Circadian clock mutants in Arabidopsis identified by luciferase imaging. Science 1995;267:1161-1163.
    • (1995) Science , vol.267 , pp. 1161-1163
    • Millar, A.J.1    Carre, I.A.2    Strayer, C.A.3    Chua, N.H.4    Kay, S.A.5
  • 77
    • 0032858233 scopus 로고    scopus 로고
    • Site-directed mutagenesis of firefly luciferase active site amino acids: A proposed model for bioluminescence color
    • Branchini BR, Magyar RA, Murtiasha MH, Anderson SM, Helgerson LC, Zimmer M. Site-directed mutagenesis of firefly luciferase active site amino acids: a proposed model for bioluminescence color. Biochemistry 1999;38:13223-13230.
    • (1999) Biochemistry , vol.38 , pp. 13223-13230
    • Branchini, B.R.1    Magyar, R.A.2    Murtiasha, M.H.3    Anderson, S.M.4    Helgerson, L.C.5    Zimmer, M.6
  • 78
    • 0025879184 scopus 로고
    • Isolation and characterization of mutants of firefly luciferase which produce different colors of light
    • Kajiyama N, Nakano E. Isolation and characterization of mutants of firefly luciferase which produce different colors of light. Protein Eng 1991;4:691-693.
    • (1991) Protein Eng , vol.4 , pp. 691-693
    • Kajiyama, N.1    Nakano, E.2
  • 79
    • 0037039437 scopus 로고    scopus 로고
    • Optical imaging of Renilla luciferase reporter gene expression in living mice
    • Bhaumik S, Gambhir SS. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci U S A 2002:99;377-382.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 377-382
    • Bhaumik, S.1    Gambhir, S.S.2
  • 80
    • 0031769343 scopus 로고    scopus 로고
    • Dual-function reporter protein for analysis of gene expression in living cells
    • Day RN, Kawecki M, Berry D. Dual-function reporter protein for analysis of gene expression in living cells. Biotechniques 1998;25:848-850, 852-854, 856.
    • (1998) Biotechniques , vol.25 , pp. 848-850
    • Day, R.N.1    Kawecki, M.2    Berry, D.3
  • 81
    • 0033629903 scopus 로고    scopus 로고
    • Visualizing and quantifying protein secretion using a Renilla luciferase-GFP fusion protein
    • Liu J, Wang Y, Szalay AA, Escher A. Visualizing and quantifying protein secretion using a Renilla luciferase-GFP fusion protein, Luminescence 2000;15:45-49.
    • (2000) Luminescence , vol.15 , pp. 45-49
    • Liu, J.1    Wang, Y.2    Szalay, A.A.3    Escher, A.4
  • 82
    • 0035140197 scopus 로고    scopus 로고
    • A study of protein-protein interactions in living cells using luminescence resonance energy transfer (LRET) from Renilla luciferase to Aequorea GFP
    • Wang Y, Wang G, O'Kane DJ, Szalay AA. A study of protein-protein interactions in living cells using luminescence resonance energy transfer (LRET) from Renilla luciferase to Aequorea GFP. Mol Gen Genet 2001;256:578-587.
    • (2001) Mol Gen Genet , vol.256 , pp. 578-587
    • Wang, Y.1    Wang, G.2    O'Kane, D.J.3    Szalay, A.A.4
  • 83
    • 0037022597 scopus 로고    scopus 로고
    • Noninvasive quantitative imaging of protein-protein interactions in living subjects
    • Ray P, Pimenta H, Paulmurugan R, et al. Noninvasive quantitative imaging of protein-protein interactions in living subjects. Proc Natl Acad Sci U S A 2002;99:3105-3110.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3105-3110
    • Ray, P.1    Pimenta, H.2    Paulmurugan, R.3
  • 84
    • 0028080347 scopus 로고
    • A proposed mechanism for the self-splicing of proteins
    • Clarke ND. A proposed mechanism for the self-splicing of proteins. Proc Natl Acad Sci U S A 1994;91:11084-11088.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11084-11088
    • Clarke, N.D.1
  • 85
    • 0028234763 scopus 로고
    • The ins and outs of protein splicing elements
    • Colston MJ, Davis EO. The ins and outs of protein splicing elements. Mol Microbiol 1994;12:359-363.
    • (1994) Mol Microbiol , vol.12 , pp. 359-363
    • Colston, M.J.1    Davis, E.O.2
  • 86
    • 0028607524 scopus 로고
    • Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins
    • Pietrokovski S. Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins. Protein Sci 1994;3:2340-2350.
    • (1994) Protein Sci , vol.3 , pp. 2340-2350
    • Pietrokovski, S.1
  • 87
    • 0035356577 scopus 로고    scopus 로고
    • Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing
    • Ozawa T, Kaihara A, Sato M, Tachihara K, Umezawa Y. Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing. Anal Chem 2001;11:2516-2521.
    • (2001) Anal Chem , vol.11 , pp. 2516-2521
    • Ozawa, T.1    Kaihara, A.2    Sato, M.3    Tachihara, K.4    Umezawa, Y.5
  • 88
    • 0030584666 scopus 로고    scopus 로고
    • Firefly luciferase: The structure is known, but the mystery remains
    • Baldwin TO. Firefly luciferase: the structure is known, but the mystery remains. Structure 1996;4;223-228.
    • (1996) Structure , vol.4 , pp. 223-228
    • Baldwin, T.O.1
  • 89
    • 0030584662 scopus 로고    scopus 로고
    • Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes
    • Conti E, Franks NP, Brick P. Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure 1996;4:287-298.
    • (1996) Structure , vol.4 , pp. 287-298
    • Conti, E.1    Franks, N.P.2    Brick, P.3
  • 90
    • 0033173841 scopus 로고    scopus 로고
    • Model of the active site of firefly luciferase
    • Sandalova TP, Ugarova NN. Model of the active site of firefly luciferase. Biochemistry (Mosc) 1999;64:962-967.
    • (1999) Biochemistry (Mosc) , vol.64 , pp. 962-967
    • Sandalova, T.P.1    Ugarova, N.N.2
  • 91
    • 0035807838 scopus 로고    scopus 로고
    • Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters
    • Iyer M, Wu L, Carey M, Wang Y, Smallwood A, Gambhir SS. Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters. Proc Natl Acad Sci U S A 2001;98:14595-14600.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14595-14600
    • Iyer, M.1    Wu, L.2    Carey, M.3    Wang, Y.4    Smallwood, A.5    Gambhir, S.S.6
  • 92
    • 0036192826 scopus 로고    scopus 로고
    • Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer
    • Zhang L, Adams JY, Billick E, et al. Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer. Mol Ther 2002;5:223-232.
    • (2002) Mol Ther , vol.5 , pp. 223-232
    • Zhang, L.1    Adams, J.Y.2    Billick, E.3


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